metformin has been researched along with aspirin in 125 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.80) | 18.7374 |
| 1990's | 1 (0.80) | 18.2507 |
| 2000's | 14 (11.20) | 29.6817 |
| 2010's | 69 (55.20) | 24.3611 |
| 2020's | 40 (32.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chen, Z; He, Y; Huang, W; Ji, C; Lee, KH; Li, S; Li, Y; Ming, Y; Morris-Natschke, SL; Niu, H; Wei, Z; Xin, G; Xing, Z; Yang, X; Yu, K; Zhang, B; Zhang, J; Zhang, X | 1 |
| Paoletti, R; Sirtori, CR; Tremoli, E | 1 |
| Nightingale, SL | 1 |
| Misumi, S; Mita, Y; Mori, M; Nagai, T; Tomizawa, T; Tonooka, N | 1 |
| Nattrass, M | 1 |
| Stiefelhagen, P | 1 |
| Boomsma, CM; Macklon, NS | 1 |
| Tan, TY; Tien, JC | 1 |
| Byrne, S; Gallagher, P; Kennedy, J; O'Mahony, D; Ryan, C | 1 |
| Arici, A; Bromer, JG; Cetinkaya, MB | 1 |
| Chang, RJ; de Ziegler, D; Meldrum, DR; Pellicer, A; Schoolcraft, WB; Scott, RT | 1 |
| Barling, RS; Echouffo-Tcheugui, JB; Griffin, SJ; Kinmonth, AL; Prevost, AT; Simmons, RK; Wareham, NJ; Williams, KM | 1 |
| Bhagra, S; Eurich, DT; Jhund, PS; Lewsey, JD; MacDonald, MR; Majumdar, SR; McAlister, FA; McMurray, JJ; Petrie, JR; Petrie, MC | 1 |
| Billestrup, N; Jacobsen, PK; Lajer, M; Mandrup-Poulsen, T; Parving, HH; Pedersen, N; Reinhard, H; Rossing, P | 1 |
| Monroe, JR | 1 |
| Brela, J; Carey, ME; Crasto, W; Daly, H; Davies, MJ; Gray, LJ; Jarvis, J; Khunti, K; Lawrence, IG; McNally, PG; Skinner, TC; Troughton, J | 1 |
| Ha, T; Koo, YX; Lim, ST; Ong, WS; Quek, R; Tai, DW; Tan, DS; Tan, IB; Tao, M | 1 |
| Han, F; Han, L; Sun, X; Wang, B; Yi, J | 1 |
| Ong, CT; Sung, SF; Tong, SH; Wu, CS | 1 |
| Albini, A; Li, VW; Li, WW; Noonan, DM; Tosetti, F | 1 |
| Cacciapuoti, F | 1 |
| Chen, WY; Holmes, MD | 1 |
| Darzynkiewicz, Z; Halicka, HD; Hsieh, TC; Lee, YS; Li, J; Wu, JM; Zhao, H | 1 |
| Fujii, G; Iigo, M; Komiya, M; Mutoh, M; Takahashi, M | 1 |
| Gronich, N; Rennert, G | 1 |
| Bosco, AA; Carvalho, Md; Duarte, RC; Dusse, LM; Fernandes, AP; Gomes, KB; Gonçalves, LH; Silva, MV | 1 |
| DiPaola, RS; Tan, XL; Yang, CS; Yue, W | 1 |
| Burkewitz, K; Mair, WB; Zhang, Y | 1 |
| Aroldi, F; Bertocchi, P; Di Biasi, B; Meriggi, F; Prochilo, T; Sabatini, T; Zaniboni, A | 1 |
| Chen, S; Lai, X; Wen, A; Xiao, T; Zhang, J; Zhu, X | 1 |
| Blagosklonny, MV | 1 |
| De Censi, A; Principi, M | 1 |
| Cuzick, J; Sestak, I | 1 |
| Adolfsson, J; Clements, M; Grönberg, H; Karlsson, R; Nordström, T | 1 |
| Blümer, RM; Bujak, AL; Crane, JD; Day, EA; Ford, RJ; Fullerton, MD; Gerstein, HC; Kemp, BE; Marcinko, K; Oakhill, JS; Pinkosky, SL; Scott, JW; Smith, BK; Steinberg, GR | 1 |
| Aksenov, V; Hans, H; Lone, A; Rollo, CD | 1 |
| Bourre, B; Lefaucheur, R; Maltête, D; Ozkul-Wermester, O; Wallon, D | 1 |
| Carpizo, D; DiPaola, RS; Huang, H; Lin, Y; Tan, XL; Xu, Q; Yang, CS; Yue, W; Zheng, X | 1 |
| Haak, HR; Herings, RM; van de Poll-Franse, LV; van Herk-Sukel, MP; Vissers, PA; Zanders, MM | 1 |
| O'Neil, BH; Sehdev, A | 1 |
| DiPaola, RS; Lin, Y; Tan, XL; Wang, T; Xu, Q; Yang, CS; Yue, W; Zachariah, E | 1 |
| Chen, C; Li, L; Li, M; Li, Y; Ou, M; Xu, X | 1 |
| Albini, A; Bertolini, F; Calleri, A; Dallaglio, K; Gregato, G; Labanca, V; Mancuso, P; Noonan, DM; Orecchioni, S; Reggiani, F; Rossi, T; Talarico, G | 1 |
| Lee, DK; Szabo, E | 1 |
| Bhattarai, D; Choi, Y; Hyeon Han, S; Jang, Y; Lee, K; Singh, S | 1 |
| Aneja, P; Horgan, AM; Knox, JJ; Le, LW; McKeever, E; McNamara, MG | 1 |
| Calzone, KA; Lubet, R; Patel, J; Rodriguez, L; Walcott, FL | 1 |
| Li, M; Liang, X; Su, Y; Wang, J; Wang, W; Zhang, F | 1 |
| Abdulhasan, M; Andresen, P; Bolnick, A; Dai, J; Howard, M; Kilburn, B; Puscheck, EE; Rappolee, DA; Shamir, AM; Xie, Y | 1 |
| Greenberg, AJ; Mucci, LA; Stopsack, KH | 1 |
| Amin, S; Boffetta, P; Lucas, AL | 1 |
| Dai, JJ; Gu, DN; Huang, Q; Jiang, MJ; Tian, L | 1 |
| Hansen, RA; Rahman, MM; Scalese, MJ | 1 |
| Nelson, SM | 1 |
| Jaffa, FM; Johnson, E; Kalyani, RR; Shubrook, JH; Skolnik, N | 1 |
| Enokido, Y; Hanada, N; Inaba, M; Kuwata, K; Mizuno, S; Morishita, T; Suzuki, Y; Wakamatsu, N; Yamada, K | 1 |
| Chambers, AC; Cotton, DE; Gash, KJ; Thomas, MG; Williams, AC | 1 |
| Abdul, MIM; Baig, MR; Gillani, SW; Sulaiman, SAS | 1 |
| Abdallah, DM; Abdelmonsif, DA; El-Hadidy, WF; Sultan, AS | 1 |
| Benyerbah, N; Ispas-Szabo, P; Mateescu, MA; Sakeer, K | 1 |
| Du, C; Liu, Y; Luo, F; Wang, Y; Zhang, N; Zhao, M | 1 |
| Amaral, MEA; Campos, MM; de Azevedo Junior, WF; Leite, CE; Nery, LR | 1 |
| Doi, N; Jinnouchi, H; Masuda, I; Matsumoto, C; Morimoto, T; Nakayama, M; Ogawa, H; Okada, S; Saito, Y; Sakuma, M; Soejima, H; Waki, M | 1 |
| Yoshida, GJ | 1 |
| Tseng, CH | 1 |
| Doctor, N; Yang, Y | 1 |
| Moyad, MA | 2 |
| Bachleitner-Hofmann, T; Briata, IM; Caviglia, S; Clavarezza, M; DeCensi, A; Gnant, M; Haefeli, WE; Mislej, EM; Oppezzi, M; Paleari, L; Petrera, M; Puntoni, M; Roth, W; Scherer, D; Stabuc, B; Ulrich, CM | 1 |
| Gonzalez, S; Hillson, O; Rallis, C | 1 |
| Brassill, MJ; Brosnan, E; Carmody, L; Clarke, H; Coogan Kelly, C; Culliney, L; Durkan, M; Egan, AM; Fenlon, M; Ferry, P; Hanlon, G; Higgins, T; Hoashi, S; Khamis, A; Kinsley, B; Kinsley, T; Kirwan, B; Liew, A; McGurk, C; McHugh, C; Murphy, MS; Murphy, P; Nolan, M; O'Halloran, D; O'Mahony, L; O'Sullivan, E; P Dunne, F; Peter, M; Roberts, G; Smyth, A; Todd, M; Tuthill, A; Wan Mahmood, WA; Yousif, O | 1 |
| Mohebbati, R; Niazmand, S; Paseban, M; Sahebkar, A; Sathyapalan, T | 1 |
| Dulak, J; Florczyk-Soluch, U; Frołow, M; Józkowicz, A; Kachamakova-Trojanowska, N; Klóska, D; Markiewicz, J; Niżankowski, R; Nowak, WN; Stępniewski, J; Taha, H; Walter, Z | 1 |
| Lagergren, J; Santoni, G; Xie, SH; Zheng, J | 1 |
| Chen, J; Gao, X; Ji, L; Luo, Y; Yang, W; Zhou, X; Zhu, Y; Zou, X | 1 |
| Dludla, PV; Louw, J; Mahlangu, TJ; Mkandla, Z; Mutize, T; Mxinwa, V; Nkambule, BB; Nyambuya, TM; Tiano, L | 1 |
| Dixon-Suen, S; Jordan, SJ; Majidi, A; Na, R; Webb, PM | 1 |
| Manoharan, R; Natarajan, SR; Ponnusamy, L; Thangaraj, K | 1 |
| Dludla, PV; Mokgalaboni, K; Mxinwa, V; Ngcobo, SR; Nkambule, BB; Nyambuya, TM; Tiano, L | 1 |
| Burov, SV; Haq, S; Harless, W; Markvicheva, E; Qorri, B; Sambi, M; Samuel, V; Szewczuk, MR | 1 |
| Dixit, G; Li, Z; Ozcan, C | 1 |
| Prasad, V; Tran, AA | 1 |
| Ho, JM; Lam, AS; Sung, JJ; Tsoi, KK; Yau, ST | 1 |
| Cho, MH; Jeong, SM; Shin, DW; Yoo, TG | 1 |
| Cho, JH; Cho, M; Jeong, SM; Kang, J; Kim, J; Shin, DW | 1 |
| Arimoto, J; Ashikari, K; Fuyuki, A; Higurashi, T; Matsuura, T; Misawa, N; Nakajima, A; Ohkubo, H; Takatsu, T; Yoshihara, T | 1 |
| El-Serag, HB; Moayyedi, P | 1 |
| Nana-Sinkam, P; Shojaee, S | 1 |
| Dludla, PV; Nkambule, BB; Nyambuya, TM | 1 |
| Carinci, F; de Lusignan, S; Feher, MD; Hinton, W; Hobbs, FDR; Joy, M; Khunti, K; Mathew, M; Munro, N; Seidu, S | 1 |
| Ai, W; Dai, Q; Guo, S; Guo, X; Li, X; Liao, W; Pan, Q; Qiu, Y; Shen, JZ; Sun, Y; Yang, W; Zhang, K; Zhang, R; Zheng, H | 1 |
| Cho, MH; Chun, S; Jeong, SM; Koo, HY; Park, J; Shin, DW | 1 |
| Chen, H; Chen, J; Chen, S; Li, W; Li, Z; Zhang, Y | 1 |
| Neumann, NR; Thompson, DC; Vasiliou, V | 1 |
| Arai, J; Arai, M; Hasatani, K; Hayakawa, Y; Honda, T; Ikeya, T; Kawahara, T; Kawai, T; Kiyotoki, S; Koike, K; Niikura, R; Nishida, T; Sumiyoshi, T; Suzuki, N; Tsuji, Y; Yamada, A; Yoshida, N | 1 |
| Bang, CS; Kim, HH; Kim, J; Kim, JY; Kim, TJ; Lee, KJ; Park, CH; Seo, SI; Shin, WG; You, SC | 1 |
| Acheampong, T; Agovino, M; Athilat, S; Lee Argov, EJ; Rodriguez, CB; Tehranifar, P; Terry, MB; Wei, Y | 1 |
| Borad, MJ; Brusselaers, N; Harmsen, WS; Marcano-Bonilla, L; Patel, T; Petersen, GM; Roberts, LR; Sadr-Azodi, O; Schleck, CD; Therneau, TM | 1 |
| Gao, B; Gao, W; Ji, Q; Wan, H; Xu, F; Zhang, X; Zhou, R | 1 |
| Aoki, T; Arai, J; Arai, M; Fujishiro, M; Hasatani, K; Hayakawa, Y; Honda, T; Ikeya, T; Ishibashi, R; Kawahara, T; Kiyotoki, S; Niikura, R; Nishida, T; Ooki, D; Sumiyoshi, T; Suzuki, N; Tsuji, Y; Yamamichi, N; Yoshida, N | 1 |
| Aleotti, F; Archibugi, L; Arcidiacono, PG; Belfiori, G; Capurso, G; Costamagna, G; Crippa, S; dell'Anna, G; Falconi, M; Gasbarrini, A; Larghi, A; Mariani, A; Nista, E; Petrone, MC; Schepis, T; Tacelli, M; Zaccari, P | 1 |
| Jing, Y; Kong, P; Sun, Y; Zhou, C; Zhuang, J; Zu, J | 1 |
| Boiani, NF; Borrely, SI; Garcia, VSG; Silva, TT; Tominaga, FK | 1 |
| Morrison, FJ; Su, M; Turchin, A | 1 |
| Attakora, J; Donkoh, IE; Ephraim, RKD; Essuman, G; Okyere, I; Okyere, P; Serwaa, D | 1 |
| Alwafi, H; Blais, JE; Chan, EW; Cheung, KS; Leung, WK; Shami, JJP; Wan, E; Wei, Y; Wong, CKH; Wong, ICK; Wong, MCS; Yan, VKC | 1 |
| Chan, KE; Chee, D; Fu, CE; Goh, XL; Huang, DQ; Kim, BK; Lee, SW; Lim, WH; Loomba, R; Muthiah, MD; Ng, CH; Nguyen, MH; Syn, N; Tamaki, N; Tan, C; Tan, DJH; Tan, EX; Xiao, J; Yong, JN; Zeng, RW | 1 |
| Broder, JC; Ernst, ME; Espinoza, S; Gibbs, P; Lockery, JE; Loomans-Kropp, HA; Orchard, SG; Polekhina, G; Wolfe, R; Woods, RL; Zoungas, S | 1 |
| Burns, A; Hartman, Y; Hunter, JB; Killeen, DE; Lora Gonzalez, MA; Manickavel, S; Walsh, E; Warram, J | 1 |
| Andreassen, BK; Botteri, E; Löfling, LL; Støer, NC; Ursin, G | 1 |
| Aminizadeh, E; Büchler, MW; Chang, DH; Golriz, M; Khajeh, E; Klotz, R; Longerich, T; Mehrabi, A; Merle, U; Moghadam, AD; Ramouz, A; Springfeld, C | 1 |
| Li, H; Li, X; Yang, F; Zhang, L; Zhao, R | 1 |
37 review(s) available for metformin and aspirin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
New strategies in the development of anti-atherosclerotic drugs.
Topics: 4-Aminobenzoic Acid; Animals; Arteriosclerosis; Aspirin; Coronary Disease; Fatty Acids, Nonesterified; Hepatomegaly; Humans; Hydrogen Peroxide; Hypolipoproteinemias; Lovastatin; Male; Metformin; Microbodies; Naphthalenes; Oligopeptides; para-Aminobenzoates; Platelet Aggregation; Rats | 1980 |
What can the clinician do to improve implantation?
Topics: Aromatase Inhibitors; Ascorbic Acid; Aspirin; Embryo Implantation; Embryo Transfer; Enzyme Inhibitors; Female; Glucocorticoids; Gonadotropin-Releasing Hormone; Humans; Hypoglycemic Agents; Metformin; Nitric Oxide Donors; Ovulation Induction; Patient Selection; Pregnancy; Progesterone; Reproductive Techniques, Assisted | 2006 |
Non-surgical interventions for threatened and recurrent miscarriages.
Topics: Abortion, Habitual; Abortion, Threatened; Antiphospholipid Syndrome; Aspirin; Bed Rest; Chorionic Gonadotropin; Education, Medical, Continuing; Evidence-Based Medicine; Female; Gestational Age; Heparin; Humans; Incidence; Metformin; Monitoring, Physiologic; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Outcome; Prenatal Diagnosis; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Singapore | 2007 |
Pretreatments before the induction of ovulation in assisted reproduction technologies: evidence-based medicine in 2007.
Topics: Adrenal Cortex Hormones; Aspirin; Contraceptives, Oral; Evidence-Based Medicine; Female; Fertilization in Vitro; Growth Hormone; Humans; Infertility; Male; Metformin; Ovulation; Ovulation Induction; Pregnancy; Randomized Controlled Trials as Topic; Reproductive Techniques, Assisted | 2008 |
Cancer prevention by targeting angiogenesis.
Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Autophagy; Cellular Senescence; Chemoprevention; Disease Progression; Fenretinide; Humans; Hypoglycemic Agents; Inflammation; Metformin; Neoplasms; Polyphenols | 2012 |
Hiding in plain view: the potential for commonly used drugs to reduce breast cancer mortality.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Breast Neoplasms; Digoxin; Drug Repositioning; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Off-Label Use | 2012 |
Prevention and intervention trials for colorectal cancer.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents; Aspirin; Clinical Trials as Topic; Colorectal Neoplasms; Disease Models, Animal; Evidence-Based Medicine; Fatty Acids, Omega-3; Humans; Hypoglycemic Agents; Japan; Lactoferrin; Metformin; Molecular Targeted Therapy; Prevalence; Primary Prevention; Randomized Controlled Trials as Topic | 2013 |
Beyond aspirin-cancer prevention with statins, metformin and bisphosphonates.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Density Conservation Agents; Diphosphonates; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Neoplasms | 2013 |
Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment.
Topics: AMP-Activated Protein Kinases; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Repositioning; Humans; Hypoglycemic Agents; Inflammation; Metformin; Pancreatic Neoplasms; TOR Serine-Threonine Kinases | 2014 |
AMPK at the nexus of energetics and aging.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Aspirin; Energy Metabolism; Humans; Metabolic Diseases; Metformin; Mitochondria; Neoplasms; Resveratrol; Stilbenes | 2014 |
Blind Snipers: Relevant Off Target Effects of Non-chemotherapeutic Agents in Oncology: Review of the Literature.
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Glycosides; Humans; Hypoglycemic Agents; Metformin; Neoplasms; Psychotropic Drugs | 2014 |
Combined cancer therapy with non-conventional drugs: all roads lead to AMPK.
Topics: AMP-Activated Protein Kinases; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Cell Line, Tumor; Cell Proliferation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Neoplasms | 2014 |
Koschei the immortal and anti-aging drugs.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Caloric Restriction; Exercise; Folklore; Gene Expression; Glucose; Humans; Insulin Resistance; Longevity; Metformin; Propranolol; Russia; Sirolimus; TOR Serine-Threonine Kinases | 2014 |
Update on breast cancer risk prediction and prevention.
Topics: Age of Onset; Aromatase Inhibitors; Aspirin; Biomarkers, Tumor; Breast Neoplasms; Diphosphonates; Female; Humans; Metformin; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome | 2015 |
The Role of Aspirin, Vitamin D, Exercise, Diet, Statins, and Metformin in the Prevention and Treatment of Colorectal Cancer.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemoprevention; Colorectal Neoplasms; Diet; Exercise; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Observational Studies as Topic; Risk Assessment; Risk Reduction Behavior; Vitamin D | 2015 |
Repurposing Drugs for Cancer Prevention.
Topics: Anticarcinogenic Agents; Aspirin; Drug Repositioning; Humans; Metformin; Neoplasms; Pioglitazone; Thiazolidinediones | 2016 |
An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs.
Topics: Antineoplastic Agents; Aspirin; Digoxin; Diphosphonates; Drug Approval; Drug Discovery; Drug Repositioning; Humans; Itraconazole; Metformin; Nelfinavir; Thalidomide | 2016 |
Hereditary cancer syndromes as model systems for chemopreventive agent development.
Topics: Adaptor Proteins, Signal Transducing; Adenomatous Polyposis Coli; Adenosine Triphosphatases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Chemoprevention; Colorectal Neoplasms, Hereditary Nonpolyposis; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; DNA Repair Enzymes; DNA-Binding Proteins; Drug Discovery; Female; Genes, APC; Genes, BRCA1; Genes, BRCA2; Hereditary Breast and Ovarian Cancer Syndrome; Humans; Hypoglycemic Agents; Li-Fraumeni Syndrome; Metformin; Mismatch Repair Endonuclease PMS2; Mutation; MutL Protein Homolog 1; MutS Homolog 2 Protein; Nuclear Proteins; Penetrance; Poly(ADP-ribose) Polymerase Inhibitors; Selective Estrogen Receptor Modulators; Tumor Suppressor Protein p53 | 2016 |
Finding New Tricks for Old Drugs: Tumoricidal Activity of Non-Traditional Antitumor Drugs.
Topics: Animals; Antineoplastic Agents; Aspirin; Clinical Trials as Topic; Flavonoids; Humans; Metformin; Neoplasms; Retrospective Studies | 2016 |
Common medications and prostate cancer mortality: a review.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metformin; Middle Aged; Nonprescription Drugs; Observational Studies as Topic; Prescription Drugs; Prostatic Neoplasms; Survival Analysis | 2017 |
The Role of Common Pharmaceutical Agents on the Prevention and Treatment of Pancreatic Cancer.
Topics: Adrenergic beta-Antagonists; Anticarcinogenic Agents; Antineoplastic Agents; Aspirin; Dipeptidyl-Peptidase IV Inhibitors; Diphosphonates; Drug Repositioning; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Pancreatic Neoplasms | 2016 |
Aspirin in pancreatic cancer: chemopreventive effects and therapeutic potentials.
Topics: Animals; Anticarcinogenic Agents; Aspirin; Cancer Pain; Humans; Metformin; Pancreatic Neoplasms | 2016 |
Prevention and management of ovarian hyperstimulation syndrome.
Topics: Aspirin; Calcium Gluconate; Cyclooxygenase Inhibitors; Disease Management; Dopamine Agonists; Female; Gonadotropin-Releasing Hormone; Humans; Hypoglycemic Agents; Metformin; Ovarian Hyperstimulation Syndrome; Ovulation Induction | 2017 |
Potentiating the effects of radiotherapy in rectal cancer: the role of aspirin, statins and metformin as adjuncts to therapy.
Topics: Aspirin; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metformin; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Radiation Tolerance; Rectal Neoplasms; Risk Factors | 2017 |
Preventing Lethal Prostate Cancer with Diet, Supplements, and Rx: Heart Healthy Continues to Be Prostate Healthy and "First Do No Harm" Part I.
Topics: Aspirin; Cardiovascular Diseases; Diet; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Style; Male; Metformin; Obesity; Prospective Studies; Prostatic Neoplasms; Risk Reduction Behavior | 2018 |
Prospects of Pharmacological Interventions to Organismal Aging.
Topics: Aging; Animals; Aspirin; Growth Hormone; Humans; Metformin; Resveratrol; Signal Transduction; TOR Serine-Threonine Kinases | 2018 |
Common medications and survival in women with ovarian cancer: A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Ovarian Neoplasms; Risk Factors; Survival Analysis | 2020 |
Preventing Lethal Prostate Cancer with Diet, Supplements, and Rx: Heart Healthy Continues to Be Prostate Healthy and "First Do No Harm" Part III.
Topics: Adult; Aspirin; Cardiovascular Diseases; Child; Diet; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Style; Male; Metformin; Obesity; Prostatic Neoplasms | 2020 |
Therapeutic aspects of AMPK in breast cancer: Progress, challenges, and future directions.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Aspirin; Biological Products; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Clinical Trials as Topic; Disease Models, Animal; Disease Progression; Enzyme Activators; Female; Humans; Metformin; Phosphorylation; Signal Transduction; Sorafenib; Treatment Outcome | 2020 |
The impact of metformin and aspirin on T-cell mediated inflammation: A systematic review of in vitro and in vivo findings.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Inflammation; Metformin; T-Lymphocytes | 2020 |
Current Status of Chemoprevention in Barrett's Esophagus.
Topics: Adenocarcinoma; Aspirin; Barrett Esophagus; Chemoprevention; Drug Therapy, Combination; Esophageal Neoplasms; Hormone Replacement Therapy; Humans; Metformin; Proton Pump Inhibitors | 2021 |
The effect of concomitant use of statins, NSAIDs, low-dose aspirin, metformin and beta-blockers on outcomes in patients receiving immune checkpoint inhibitors: a systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immune Checkpoint Inhibitors; Metformin | 2021 |
AMPK activators for the prevention and treatment of neurodegenerative diseases.
Topics: AMP-Activated Protein Kinases; Animals; Aspirin; Enzyme Activators; Humans; Metformin; Momordica charantia; Neurodegenerative Diseases; Neuroprotective Agents | 2021 |
Aspirin, metformin, and statin use on the risk of gastric cancer: A nationwide population-based cohort study in Korea with systematic review and meta-analysis.
Topics: Aspirin; Cohort Studies; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Republic of Korea; Stomach Neoplasms | 2022 |
Meta-analysis: Chemoprevention of hepatocellular carcinoma with statins, aspirin and metformin.
Topics: Aspirin; Carcinoma, Hepatocellular; Chemoprevention; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Metformin | 2023 |
Impact of concomitant medications on the efficacy of immune checkpoint inhibitors: an umbrella review.
Topics: Analgesics, Opioid; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Esophageal Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immune Checkpoint Inhibitors; Kidney Neoplasms; Liver Neoplasms; Melanoma; Meta-Analysis as Topic; Metformin; Steroids; Systematic Reviews as Topic | 2023 |
9 trial(s) available for metformin and aspirin
| Article | Year |
|---|---|
The ADDITION-Cambridge trial protocol: a cluster -- randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients.
Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Early Diagnosis; Humans; Hypoglycemic Agents; Mass Screening; Metformin; Middle Aged; Sodium Chloride Symporter Inhibitors | 2009 |
Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: the Microalbuminuria Education and Medication Optimisation (MEMO) study.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Antihypertensive Agents; Aspirin; Blood Pressure; Cholesterol; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Male; Metformin; Middle Aged; Risk Factors | 2011 |
Acetylsalicylic acid therapy: influence of metformin use and other variables on urinary 11-dehydrothromboxane B2 levels.
Topics: Aspirin; Biological Transport; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Hypoglycemic Agents; Insulin Resistance; Intestinal Absorption; Male; Metformin; Middle Aged; Oxidative Stress; Risk Factors; Thromboxane B2 | 2014 |
Combined effect of metformin with ascorbic acid versus acetyl salicylic acid on diabetes-related cardiovascular complication; a 12-month single blind multicenter randomized control trial.
Topics: Adult; Ascorbic Acid; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Single-Blind Method | 2017 |
Effect of Aspirin on Cancer Chemoprevention in Japanese Patients With Type 2 Diabetes: 10-Year Observational Follow-up of a Randomized Controlled Trial.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Chemoprevention; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Incidence; Japan; Male; Metformin; Middle Aged; Neoplasms | 2018 |
The ASAMET trial: a randomized, phase II, double-blind, placebo-controlled, multicenter, 2 × 2 factorial biomarker study of tertiary prevention with low-dose aspirin and metformin in stage I-III colorectal cancer patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Biomarkers, Tumor; Colorectal Neoplasms; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Follow-Up Studies; Humans; Hypoglycemic Agents; Metformin; Tertiary Prevention | 2018 |
The efficacy of aspirin and metformin combination therapy in patients with rectal aberrant crypt foci: a double-blinded randomized controlled trial.
Topics: Aberrant Crypt Foci; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Double-Blind Method; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Metformin; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic | 2020 |
Efficacy and safety of alogliptin versus acarbose in Chinese type 2 diabetes patients with high cardiovascular risk or coronary heart disease treated with aspirin and inadequately controlled with metformin monotherapy or drug-naive: A multicentre, randomi
Topics: Acarbose; Adult; Aspirin; Coronary Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Glycated Hemoglobin; Heart Disease Risk Factors; Humans; Hypoglycemic Agents; Metformin; Piperidines; Prospective Studies; Treatment Outcome; Uracil | 2022 |
Association of metformin, aspirin, and cancer incidence with mortality risk in adults with diabetes.
Topics: Aged; Aspirin; Diabetes Mellitus, Type 2; Humans; Incidence; Metformin; Neoplasms | 2023 |
79 other study(ies) available for metformin and aspirin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Novel potent antiplatelet thrombotic agent derived from biguanide for ischemic stroke.
Topics: Administration, Oral; Animals; Biguanides; Brain Ischemia; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Stroke; Structure-Activity Relationship; Thrombosis | 2020 |
From the Food and Drug Administration.
Topics: Aspirin; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Labeling; Drugs, Investigational; Heart Diseases; Humans; Metformin; Product Surveillance, Postmarketing; United States; United States Food and Drug Administration | 1993 |
Diabetes mellitus with left transverse sinus thrombosis and right transverse sinus aplasia.
Topics: Aged; Aspirin; Cerebral Angiography; Cranial Sinuses; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diet, Diabetic; Female; Fibrinolytic Agents; Headache; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Metformin; Sinus Thrombosis, Intracranial; Ticlopidine; Tomography, X-Ray Computed; Urokinase-Type Plasminogen Activator | 2001 |
Management of hyperglycaemia in the patient with acute myocardial infarction.
Topics: Aspirin; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Metformin; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy | 2003 |
[Stroke is not equal to stroke. Keep track of the causes].
Topics: Adult; Antihypertensive Agents; Aspirin; Carotid Artery, Common; Carotid Artery, External; Carotid Stenosis; Diabetes Mellitus, Type 2; Echocardiography; Echocardiography, Doppler; Electrocardiography; Female; Fibrinolytic Agents; Heart Aneurysm; Heart Diseases; Humans; Hypertension; Hypoglycemic Agents; Intracranial Embolism; Male; Metformin; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Thrombosis; Ultrasonography, Doppler, Color | 2003 |
STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation.
Topics: Abbreviations as Topic; Age Factors; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bendroflumethiazide; Clopidogrel; Delphi Technique; Digoxin; Diuretics; Drug Prescriptions; Drug Therapy; Drug Utilization Review; Drug-Related Side Effects and Adverse Reactions; Glomerular Filtration Rate; Health Services for the Aged; Humans; Ireland; Metformin; Practice Patterns, Physicians'; Reproducibility of Results; Risk Factors; Ticlopidine; Time Factors; United Kingdom | 2008 |
Adjuncts for ovarian stimulation: when do we adopt "orphan indications" for approved drugs?
Topics: Androgens; Aspirin; Contraceptives, Oral; Dopamine Agonists; Estrogens; Female; Fertilization in Vitro; Human Growth Hormone; Humans; Leuprolide; Metformin; Orphan Drug Production; Ovulation Induction; Polycystic Ovary Syndrome | 2009 |
Treatment of type 2 diabetes and outcomes in patients with heart failure: a nested case-control study from the U.K. General Practice Research Database.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Case-Control Studies; Diabetes Mellitus, Type 2; Digoxin; Female; Heart Failure; Humans; Hypoglycemic Agents; Male; Metformin; United Kingdom | 2010 |
Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes.
Topics: Angiotensin Receptor Antagonists; Aspirin; Cell Count; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, Reducing; Endothelial Cells; Exercise Therapy; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukocytes, Mononuclear; Life Style; Male; Metformin; Stem Cells; Treatment Outcome | 2010 |
What are these lesions that spread from the lips. Fixed drug eruption.
Topics: Adult; Aspirin; Biopsy, Needle; Drug Eruptions; Female; Humans; Hypoglycemic Agents; Metformin; Nonprescription Drugs | 2010 |
Effect of concomitant statin, metformin, or aspirin on rituximab treatment for diffuse large B-cell lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Lymphoma, Large B-Cell, Diffuse; Male; Metformin; Middle Aged; Prednisone; Rituximab; Treatment Outcome; Vincristine; Young Adult | 2011 |
Effect of aspirin on the expression of hepatocyte NF-κB and serum TNF-α in streptozotocin-induced type 2 diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Male; Metformin; NF-kappa B; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2011 |
Multiple cerebral infarctions related to famotidine-induced eosinophilia.
Topics: Acarbose; Adrenergic alpha-1 Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Cerebral Infarction; Diabetes Mellitus, Type 2; Diffusion Magnetic Resonance Imaging; Drug-Related Side Effects and Adverse Reactions; Eosinophilia; Famotidine; Humans; Hypertension; Hypoglycemic Agents; Labetalol; Male; Metformin; Middle Aged; Nifedipine; Peptic Ulcer; Prazosin; Sulfonylurea Compounds | 2012 |
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6 | 2012 |
Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling.
Topics: Adaptor Proteins, Signal Transducing; Aspirin; Ataxia Telangiectasia Mutated Proteins; Berberine; Cell Cycle Proteins; Cell Line, Tumor; Cellular Senescence; Cholecalciferol; Deoxyglucose; DNA Damage; DNA-Binding Proteins; Down-Regulation; Enzyme Activation; Flow Cytometry; Histones; Humans; Laser Scanning Cytometry; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Oxidative Stress; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Resveratrol; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins | 2012 |
Prevention of colorectal adenomas.
Topics: Adenoma; Aspirin; Colorectal Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Ligands; Lignin; Metformin; Phytoestrogens; Silymarin | 2015 |
The risk of prostate cancer for men on aspirin, statin or antidiabetic medications.
Topics: Aspirin; Cohort Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Metformin; Middle Aged; Prostatic Neoplasms; Retrospective Studies; Risk Factors; Sweden | 2015 |
Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity.
Topics: AMP-Activated Protein Kinases; Animals; Aspirin; Cardiotonic Agents; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Synergism; Enzyme Activation; Hepatocytes; Humans; Hypoglycemic Agents; Insulin Resistance; Lipogenesis; Liver; Male; Metformin; Mice; Mice, Inbred C57BL | 2015 |
Impacts of metformin and aspirin on life history features and longevity of crickets: trade-offs versus cost-free life extension?
Topics: Animals; Aspirin; Female; Gryllidae; Longevity; Male; Metformin | 2015 |
Stroke mimicking relapse in a patient with CLIPPERS syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aspirin; Brain Stem; Encephalomyelitis; Gadolinium; Humans; Hypoglycemic Agents; Inflammation; Magnetic Resonance Imaging; Male; Metformin; Middle Aged; Recurrence; Simvastatin; Stroke | 2015 |
Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Aspirin; Bcl-2-Like Protein 11; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Survival; Cyclin D1; Female; Humans; Membrane Proteins; Metformin; Mice; Mice, SCID; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Wound Healing | 2015 |
Are metformin, statin and aspirin use still associated with overall mortality among colorectal cancer patients with diabetes if adjusted for one another?
Topics: Aged; Aged, 80 and over; Aspirin; Colorectal Neoplasms; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Metformin; Middle Aged; Registries; Risk Factors; Survival Analysis | 2015 |
Transcriptomic analysis of pancreatic cancer cells in response to metformin and aspirin: an implication of synergy.
Topics: Aspirin; Cell Line, Tumor; Down-Regulation; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Metformin; Pancreatic Neoplasms; Reproducibility of Results; RNA, Messenger; Signal Transduction | 2015 |
[Impact of sitagliptin on aspirin resistance in patients with Type 2 diabetes mellitus].
Topics: Aspirin; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Drug Resistance; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Metformin; Oxidative Stress; Sitagliptin Phosphate | 2015 |
Aspirin and atenolol enhance metformin activity against breast cancer by targeting both neoplastic and microenvironment cells.
Topics: Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Atenolol; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Electron Transport Complex I; Female; Humans; Metformin; NAD; Neoplasm Metastasis; Stem Cells; Triple Negative Breast Neoplasms; Tumor Burden; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2016 |
Effects of Statin, Aspirin or Metformin Use on Recurrence-Free and Overall Survival in Patients with Biliary Tract Cancer.
Topics: Aged; Aspirin; Biliary Tract Neoplasms; Cardiovascular Agents; Comorbidity; Disease Progression; Disease-Free Survival; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Kaplan-Meier Estimate; Male; Metformin; Multivariate Analysis; Neoplasm Recurrence, Local; Proportional Hazards Models; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome | 2015 |
Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos.
Topics: AMP-Activated Protein Kinases; Animals; Aspirin; Dietary Supplements; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Fertility Agents; Indoles; Metformin; Mice; Sorbitol; Stem Cells; Stress, Physiological | 2016 |
Dipeptidyl Peptidase-4 Inhibitor-Associated Risk of Bleeding: An Evaluation of Reported Adverse Events.
Topics: Adverse Drug Reaction Reporting Systems; Aspirin; Clopidogrel; Dipeptidyl-Peptidase IV Inhibitors; Hemorrhage; Humans; Hypoglycemic Agents; Metformin; Odds Ratio; Platelet Aggregation Inhibitors; Retrospective Studies; Risk; Ticlopidine | 2017 |
Reducing CV risk in diabetes: An ADA update.
Topics: Antihypertensive Agents; Aspirin; Benzhydryl Compounds; Cardiovascular Diseases; Contraindications; Creatinine; Diabetes Complications; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Drug Chronotherapy; Ezetimibe; Fenofibrate; Glucosides; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Hypolipidemic Agents; Life Style; Liraglutide; Metformin; Niacin; PCSK9 Inhibitors; Platelet Aggregation Inhibitors; Risk Reduction Behavior; Thiazolidinediones | 2017 |
The effect of rapamycin, NVP-BEZ235, aspirin, and metformin on PI3K/AKT/mTOR signaling pathway of PIK3CA-related overgrowth spectrum (PROS).
Topics: Adult; Aspirin; Child, Preschool; Class I Phosphatidylinositol 3-Kinases; DNA Mutational Analysis; Dose-Response Relationship, Drug; Female; Fibroblasts; Genetic Association Studies; Growth Disorders; Humans; Imidazoles; Male; Metformin; Mutation; Phenotype; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinolines; Signal Transduction; TOR Serine-Threonine Kinases | 2017 |
Targeting AMPK, mTOR and β-Catenin by Combined Metformin and Aspirin Therapy in HCC: An Appraisal in Egyptian HCC Patients.
Topics: Adult; AMP-Activated Protein Kinases; Antineoplastic Combined Chemotherapy Protocols; Aspirin; beta Catenin; Carcinoma, Hepatocellular; Cell Survival; Egypt; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; Metformin; Middle Aged; Phosphorylation; TOR Serine-Threonine Kinases; Up-Regulation | 2018 |
Ampholytic starch excipients for high loaded drug formulations: Mechanistic insights.
Topics: Acetaminophen; Aspirin; Drug Compounding; Excipients; Mesalamine; Metformin; Starch; Tablets; Viscosity | 2018 |
Aspirin and metformin exhibit antitumor activity in murine breast cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aspirin; Breast Neoplasms; Cell Proliferation; Female; Humans; Hypoglycemic Agents; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; Signal Transduction; Transforming Growth Factor beta; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2018 |
Pre-clinical effects of metformin and aspirin on the cell lines of different breast cancer subtypes.
Topics: Antineoplastic Agents; Aspirin; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Synergism; Humans; Metformin; Receptors, Estrogen | 2018 |
Comment on "Targeting AMPK, mTOR and β-Catenin by Combined Metformin and Aspirin Therapy in HCC: An Appraisal in Egyptian HCC Patients".
Topics: Aspirin; beta Catenin; Egypt; Humans; Metformin; TOR Serine-Threonine Kinases | 2018 |
Metformin and risk of hepatocellular carcinoma in patients with type 2 diabetes.
Topics: Aged; Aspirin; Carcinoma, Hepatocellular; Cohort Studies; Databases, Factual; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Incidence; Liver Neoplasms; Male; Metformin; Middle Aged; Propensity Score; Proportional Hazards Models; Risk Factors; Risk Reduction Behavior; Taiwan | 2018 |
Separation and Analysis of Aspirin and Metformin HCl Using Green Subcritical Water Chromatography.
Topics: Aspirin; Chromatography, High Pressure Liquid; Metformin | 2018 |
An Irish National Diabetes in Pregnancy Audit: aiming for best outcomes for women with diabetes.
Topics: Abortion, Spontaneous; Adult; Aspirin; Cesarean Section; Clinical Audit; Delivery of Health Care; Delivery, Obstetric; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Fetal Macrosomia; Folic Acid; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Infant, Newborn; Infusion Pumps, Implantable; Insulin; Insulin Infusion Systems; Intensive Care Units, Neonatal; Ireland; Live Birth; Mass Screening; Metformin; Platelet Aggregation Inhibitors; Preconception Care; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome; Premature Birth; Retrospective Studies; Stillbirth; Vitamin B Complex | 2020 |
Comparison of the Neuroprotective Effects of Aspirin, Atorvastatin, Captopril and Metformin in Diabetes Mellitus.
Topics: Animals; Aspirin; Atorvastatin; Captopril; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Metformin; Neuroprotective Agents; Rats; Rats, Wistar; Streptozocin | 2019 |
Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity
Topics: AC133 Antigen; Antigens, CD34; Aspirin; Atorvastatin; Cells, Cultured; Culture Media, Conditioned; Hematopoietic Stem Cells; Heme Oxygenase-1; Humans; Immunoassay; Isothiocyanates; Leukocytes, Mononuclear; Metformin; Neovascularization, Physiologic; Phenotype; Resveratrol; Sulfoxides | 2019 |
Metformin use and risk of gastric adenocarcinoma in a Swedish population-based cohort study.
Topics: Adenocarcinoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Helicobacter Infections; Helicobacter pylori; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metformin; Middle Aged; Proportional Hazards Models; Risk Factors; Stomach Neoplasms; Sweden | 2019 |
A Decision-Support Software to Improve the Standard Care in Chinese Type 2 Diabetes.
Topics: Antihypertensive Agents; Aspirin; Blood Glucose; Blood Pressure; Cardiovascular Diseases; China; Decision Support Systems, Clinical; Diabetes Mellitus, Type 2; Guideline Adherence; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Quality Improvement; Quality of Health Care; Secondary Prevention; Software | 2019 |
Elevated T-helper 2 cytokine levels in high fat diet-fed C57BL/6 mice are attenuated by short-term 6-week treatment with a combination of low-dose aspirin and metformin.
Topics: Animals; Aspirin; Cytokines; Drug Therapy, Combination; Glucose Intolerance; Male; Metformin; Mice; Mice, Inbred C57BL; Th1 Cells; Th17 Cells; Th2 Cells | 2020 |
A Triple Combination of Metformin, Acetylsalicylic Acid, and Oseltamivir Phosphate Impacts Tumour Spheroid Viability and Upends Chemoresistance in Triple-Negative Breast Cancer.
Topics: Aldehyde Dehydrogenase 1 Family; Antineoplastic Agents; Apoptosis; Aspirin; Breast Neoplasms; CD24 Antigen; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Hyaluronan Receptors; Metformin; Oseltamivir; Retinal Dehydrogenase; Spheroids, Cellular; Tamoxifen; Triple Negative Breast Neoplasms; Tumor Cells, Cultured | 2020 |
Activation of AMP-Activated Protein Kinases Prevents Atrial Fibrillation.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrillation; Atrial Remodeling; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Female; Fibrosis; Heart Rate; Male; Metformin; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Myocytes, Cardiac; Primary Prevention | 2021 |
Drug repurposing for cancer treatments: a well-intentioned, but misguided strategy.
Topics: Aspirin; Drug Repositioning; Humans; Metformin; Neoplasms; Vitamin D | 2020 |
Use of metformin and aspirin is associated with delayed cancer incidence.
Topics: Aged; Aged, 80 and over; Aspirin; Delayed Diagnosis; Female; Humans; Incidence; Male; Metformin; Middle Aged; Neoplasms; Retrospective Studies | 2020 |
Association of Aspirin, Metformin, and Statin Use with Gastric Cancer Incidence and Mortality: A Nationwide Cohort Study.
Topics: Adult; Aged; Aspirin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Metformin; Middle Aged; Mortality; Republic of Korea; Retrospective Studies; Stomach Neoplasms | 2021 |
The Associations of Aspirin, Statins, and Metformin With Lung Cancer Risk and Related Mortality: A Time-Dependent Analysis of Population-Based Nationally Representative Data.
Topics: Aspirin; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Neoplasms; Metformin | 2021 |
One Metformin a Day, Keeps Lung Cancer Away! Or Does It?
Topics: Aspirin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Lung Neoplasms; Metformin | 2021 |
The aberrant expression of CD69 on peripheral T-helper cells in diet-induced inflammation is ameliorated by low-dose aspirin and metformin treatment.
Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Disease Models, Animal; Gene Expression; Hypoglycemic Agents; Inflammation; Lectins, C-Type; Male; Metformin; Mice; Mice, Inbred C57BL; T-Lymphocytes, Helper-Inducer | 2021 |
Dashboards to reduce inappropriate prescribing of metformin and aspirin: A quality assurance programme in a primary care sentinel network.
Topics: Aspirin; Diabetes Mellitus, Type 2; Humans; Inappropriate Prescribing; Metformin; Primary Health Care | 2021 |
Metformin Targets Foxo1 to Control Glucose Homeostasis.
Topics: Animals; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Forkhead Box Protein O1; Gluconeogenesis; Glucose; Hepatocytes; Homeostasis; Humans; Insulin Resistance; Liver; Male; Metformin; Mice; Mice, Knockout; Middle Aged; Phosphorylation; Signal Transduction; Streptozocin | 2021 |
Population-wide impacts of aspirin, statins, and metformin use on prostate cancer incidence and mortality.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cohort Studies; Health Surveys; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Incidence; Longitudinal Studies; Male; Metformin; Middle Aged; Proportional Hazards Models; Prostatic Neoplasms; Republic of Korea | 2021 |
Chemoprevention of Oesophageal Squamous-Cell Carcinoma and Adenocarcinoma: A Multicentre Retrospective Cohort Study.
Topics: Adenocarcinoma; Aspirin; Case-Control Studies; Chemoprevention; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Proton Pump Inhibitors; Retrospective Studies; Risk Factors | 2022 |
Current regular aspirin use and mammographic breast density: a cross-sectional analysis considering concurrent statin and metformin use.
Topics: Adult; Aspirin; Breast Density; Breast Neoplasms; Cross-Sectional Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mammography; Metformin; Middle Aged; Pregnancy; Risk Factors | 2022 |
Aspirin, Statins, Non-aspirin NSAIDs, Metformin, and the Risk of Biliary Cancer: A Swedish Population-Based Cohort Study.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biliary Tract Neoplasms; Cohort Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Risk Factors; Sweden | 2022 |
Chemoprevention for Colorectal Cancers: Are Chemopreventive Effects Different Between Left and Right Sided Colorectal Cancers?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Metformin; Retrospective Studies | 2022 |
Risk factors for the occurrence of ampullary tumors: A case-control study.
Topics: Adenoma; Ampulla of Vater; Aspirin; Carcinoma; Case-Control Studies; Common Bile Duct Neoplasms; Duodenal Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulins; Metformin; Pancreatic Neoplasms; Proton Pump Inhibitors; Risk Factors | 2022 |
Bioinformatic Data Mining for Candidate Drugs Affecting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) in Cancer Patients.
Topics: Androgen Antagonists; Androgens; Aspirin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Caspases; Computational Biology; Data Mining; Humans; Leukocytes, Mononuclear; Metformin; Multiple Myeloma; Progesterone; Thrombin; Vitamin D | 2022 |
Acute and chronic ecotoxicological effects of pharmaceuticals and their mixtures in Daphnia similis.
Topics: Animals; Anti-Bacterial Agents; Aspirin; Ciprofloxacin; Daphnia; Fluoxetine; Hypoglycemic Agents; Metformin; Pharmaceutical Preparations; Water; Water Pollutants, Chemical | 2022 |
COVID-19 outcomes in patients taking cardioprotective medications.
Topics: Aspirin; COVID-19; COVID-19 Drug Treatment; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Retrospective Studies; SARS-CoV-2 | 2022 |
Conservative therapy is associated with worse clinical features and biochemical derangements than renal replacement therapy: a retrospective study in Kumasi, Ghana.
Topics: Adult; Aspirin; Bisoprolol; Conservative Treatment; Furosemide; Ghana; Humans; Irbesartan; Kidney Failure, Chronic; Lisinopril; Metformin; Middle Aged; Nifedipine; Ranitidine; Renal Replacement Therapy; Retrospective Studies; Sodium | 2022 |
Low-dose aspirin does not lower the risk of colorectal cancer in patients with type 2 diabetes taking metformin.
Topics: Adult; Aspirin; Cohort Studies; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin | 2023 |
Metformin Reduces Tumor Growth in a Murine Flank Schwannoma Model.
Topics: Animals; Aspirin; Metformin; Mice; Mice, Nude; Neurilemmoma; Neuroma, Acoustic; Rats | 2023 |
Low-dose aspirin, statins, and metformin and survival in patients with breast cancers: a Norwegian population-based cohort study.
Topics: Aspirin; Breast Neoplasms; Cohort Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Norway; Receptors, Estrogen | 2023 |
Association of perioperative use of statins, metformin, and aspirin with recurrence after curative liver resection in patients with hepatocellular carcinoma: A propensity score matching analysis.
Topics: Aspirin; Carcinoma, Hepatocellular; Hepatectomy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Metformin; Propensity Score; Retrospective Studies | 2023 |