metformin and aspirin

metformin has been researched along with aspirin in 125 studies

Research

Studies (125)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.80)18.7374
1990's1 (0.80)18.2507
2000's14 (11.20)29.6817
2010's69 (55.20)24.3611
2020's40 (32.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, Z; He, Y; Huang, W; Ji, C; Lee, KH; Li, S; Li, Y; Ming, Y; Morris-Natschke, SL; Niu, H; Wei, Z; Xin, G; Xing, Z; Yang, X; Yu, K; Zhang, B; Zhang, J; Zhang, X1
Paoletti, R; Sirtori, CR; Tremoli, E1
Nightingale, SL1
Misumi, S; Mita, Y; Mori, M; Nagai, T; Tomizawa, T; Tonooka, N1
Nattrass, M1
Stiefelhagen, P1
Boomsma, CM; Macklon, NS1
Tan, TY; Tien, JC1
Byrne, S; Gallagher, P; Kennedy, J; O'Mahony, D; Ryan, C1
Arici, A; Bromer, JG; Cetinkaya, MB1
Chang, RJ; de Ziegler, D; Meldrum, DR; Pellicer, A; Schoolcraft, WB; Scott, RT1
Barling, RS; Echouffo-Tcheugui, JB; Griffin, SJ; Kinmonth, AL; Prevost, AT; Simmons, RK; Wareham, NJ; Williams, KM1
Bhagra, S; Eurich, DT; Jhund, PS; Lewsey, JD; MacDonald, MR; Majumdar, SR; McAlister, FA; McMurray, JJ; Petrie, JR; Petrie, MC1
Billestrup, N; Jacobsen, PK; Lajer, M; Mandrup-Poulsen, T; Parving, HH; Pedersen, N; Reinhard, H; Rossing, P1
Monroe, JR1
Brela, J; Carey, ME; Crasto, W; Daly, H; Davies, MJ; Gray, LJ; Jarvis, J; Khunti, K; Lawrence, IG; McNally, PG; Skinner, TC; Troughton, J1
Ha, T; Koo, YX; Lim, ST; Ong, WS; Quek, R; Tai, DW; Tan, DS; Tan, IB; Tao, M1
Han, F; Han, L; Sun, X; Wang, B; Yi, J1
Ong, CT; Sung, SF; Tong, SH; Wu, CS1
Albini, A; Li, VW; Li, WW; Noonan, DM; Tosetti, F1
Cacciapuoti, F1
Chen, WY; Holmes, MD1
Darzynkiewicz, Z; Halicka, HD; Hsieh, TC; Lee, YS; Li, J; Wu, JM; Zhao, H1
Fujii, G; Iigo, M; Komiya, M; Mutoh, M; Takahashi, M1
Gronich, N; Rennert, G1
Bosco, AA; Carvalho, Md; Duarte, RC; Dusse, LM; Fernandes, AP; Gomes, KB; Gonçalves, LH; Silva, MV1
DiPaola, RS; Tan, XL; Yang, CS; Yue, W1
Burkewitz, K; Mair, WB; Zhang, Y1
Aroldi, F; Bertocchi, P; Di Biasi, B; Meriggi, F; Prochilo, T; Sabatini, T; Zaniboni, A1
Chen, S; Lai, X; Wen, A; Xiao, T; Zhang, J; Zhu, X1
Blagosklonny, MV1
De Censi, A; Principi, M1
Cuzick, J; Sestak, I1
Adolfsson, J; Clements, M; Grönberg, H; Karlsson, R; Nordström, T1
Blümer, RM; Bujak, AL; Crane, JD; Day, EA; Ford, RJ; Fullerton, MD; Gerstein, HC; Kemp, BE; Marcinko, K; Oakhill, JS; Pinkosky, SL; Scott, JW; Smith, BK; Steinberg, GR1
Aksenov, V; Hans, H; Lone, A; Rollo, CD1
Bourre, B; Lefaucheur, R; Maltête, D; Ozkul-Wermester, O; Wallon, D1
Carpizo, D; DiPaola, RS; Huang, H; Lin, Y; Tan, XL; Xu, Q; Yang, CS; Yue, W; Zheng, X1
Haak, HR; Herings, RM; van de Poll-Franse, LV; van Herk-Sukel, MP; Vissers, PA; Zanders, MM1
O'Neil, BH; Sehdev, A1
DiPaola, RS; Lin, Y; Tan, XL; Wang, T; Xu, Q; Yang, CS; Yue, W; Zachariah, E1
Chen, C; Li, L; Li, M; Li, Y; Ou, M; Xu, X1
Albini, A; Bertolini, F; Calleri, A; Dallaglio, K; Gregato, G; Labanca, V; Mancuso, P; Noonan, DM; Orecchioni, S; Reggiani, F; Rossi, T; Talarico, G1
Lee, DK; Szabo, E1
Bhattarai, D; Choi, Y; Hyeon Han, S; Jang, Y; Lee, K; Singh, S1
Aneja, P; Horgan, AM; Knox, JJ; Le, LW; McKeever, E; McNamara, MG1
Calzone, KA; Lubet, R; Patel, J; Rodriguez, L; Walcott, FL1
Li, M; Liang, X; Su, Y; Wang, J; Wang, W; Zhang, F1
Abdulhasan, M; Andresen, P; Bolnick, A; Dai, J; Howard, M; Kilburn, B; Puscheck, EE; Rappolee, DA; Shamir, AM; Xie, Y1
Greenberg, AJ; Mucci, LA; Stopsack, KH1
Amin, S; Boffetta, P; Lucas, AL1
Dai, JJ; Gu, DN; Huang, Q; Jiang, MJ; Tian, L1
Hansen, RA; Rahman, MM; Scalese, MJ1
Nelson, SM1
Jaffa, FM; Johnson, E; Kalyani, RR; Shubrook, JH; Skolnik, N1
Enokido, Y; Hanada, N; Inaba, M; Kuwata, K; Mizuno, S; Morishita, T; Suzuki, Y; Wakamatsu, N; Yamada, K1
Chambers, AC; Cotton, DE; Gash, KJ; Thomas, MG; Williams, AC1
Abdul, MIM; Baig, MR; Gillani, SW; Sulaiman, SAS1
Abdallah, DM; Abdelmonsif, DA; El-Hadidy, WF; Sultan, AS1
Benyerbah, N; Ispas-Szabo, P; Mateescu, MA; Sakeer, K1
Du, C; Liu, Y; Luo, F; Wang, Y; Zhang, N; Zhao, M1
Amaral, MEA; Campos, MM; de Azevedo Junior, WF; Leite, CE; Nery, LR1
Doi, N; Jinnouchi, H; Masuda, I; Matsumoto, C; Morimoto, T; Nakayama, M; Ogawa, H; Okada, S; Saito, Y; Sakuma, M; Soejima, H; Waki, M1
Yoshida, GJ1
Tseng, CH1
Doctor, N; Yang, Y1
Moyad, MA2
Bachleitner-Hofmann, T; Briata, IM; Caviglia, S; Clavarezza, M; DeCensi, A; Gnant, M; Haefeli, WE; Mislej, EM; Oppezzi, M; Paleari, L; Petrera, M; Puntoni, M; Roth, W; Scherer, D; Stabuc, B; Ulrich, CM1
Gonzalez, S; Hillson, O; Rallis, C1
Brassill, MJ; Brosnan, E; Carmody, L; Clarke, H; Coogan Kelly, C; Culliney, L; Durkan, M; Egan, AM; Fenlon, M; Ferry, P; Hanlon, G; Higgins, T; Hoashi, S; Khamis, A; Kinsley, B; Kinsley, T; Kirwan, B; Liew, A; McGurk, C; McHugh, C; Murphy, MS; Murphy, P; Nolan, M; O'Halloran, D; O'Mahony, L; O'Sullivan, E; P Dunne, F; Peter, M; Roberts, G; Smyth, A; Todd, M; Tuthill, A; Wan Mahmood, WA; Yousif, O1
Mohebbati, R; Niazmand, S; Paseban, M; Sahebkar, A; Sathyapalan, T1
Dulak, J; Florczyk-Soluch, U; Frołow, M; Józkowicz, A; Kachamakova-Trojanowska, N; Klóska, D; Markiewicz, J; Niżankowski, R; Nowak, WN; Stępniewski, J; Taha, H; Walter, Z1
Lagergren, J; Santoni, G; Xie, SH; Zheng, J1
Chen, J; Gao, X; Ji, L; Luo, Y; Yang, W; Zhou, X; Zhu, Y; Zou, X1
Dludla, PV; Louw, J; Mahlangu, TJ; Mkandla, Z; Mutize, T; Mxinwa, V; Nkambule, BB; Nyambuya, TM; Tiano, L1
Dixon-Suen, S; Jordan, SJ; Majidi, A; Na, R; Webb, PM1
Manoharan, R; Natarajan, SR; Ponnusamy, L; Thangaraj, K1
Dludla, PV; Mokgalaboni, K; Mxinwa, V; Ngcobo, SR; Nkambule, BB; Nyambuya, TM; Tiano, L1
Burov, SV; Haq, S; Harless, W; Markvicheva, E; Qorri, B; Sambi, M; Samuel, V; Szewczuk, MR1
Dixit, G; Li, Z; Ozcan, C1
Prasad, V; Tran, AA1
Ho, JM; Lam, AS; Sung, JJ; Tsoi, KK; Yau, ST1
Cho, MH; Jeong, SM; Shin, DW; Yoo, TG1
Cho, JH; Cho, M; Jeong, SM; Kang, J; Kim, J; Shin, DW1
Arimoto, J; Ashikari, K; Fuyuki, A; Higurashi, T; Matsuura, T; Misawa, N; Nakajima, A; Ohkubo, H; Takatsu, T; Yoshihara, T1
El-Serag, HB; Moayyedi, P1
Nana-Sinkam, P; Shojaee, S1
Dludla, PV; Nkambule, BB; Nyambuya, TM1
Carinci, F; de Lusignan, S; Feher, MD; Hinton, W; Hobbs, FDR; Joy, M; Khunti, K; Mathew, M; Munro, N; Seidu, S1
Ai, W; Dai, Q; Guo, S; Guo, X; Li, X; Liao, W; Pan, Q; Qiu, Y; Shen, JZ; Sun, Y; Yang, W; Zhang, K; Zhang, R; Zheng, H1
Cho, MH; Chun, S; Jeong, SM; Koo, HY; Park, J; Shin, DW1
Chen, H; Chen, J; Chen, S; Li, W; Li, Z; Zhang, Y1
Neumann, NR; Thompson, DC; Vasiliou, V1
Arai, J; Arai, M; Hasatani, K; Hayakawa, Y; Honda, T; Ikeya, T; Kawahara, T; Kawai, T; Kiyotoki, S; Koike, K; Niikura, R; Nishida, T; Sumiyoshi, T; Suzuki, N; Tsuji, Y; Yamada, A; Yoshida, N1
Bang, CS; Kim, HH; Kim, J; Kim, JY; Kim, TJ; Lee, KJ; Park, CH; Seo, SI; Shin, WG; You, SC1
Acheampong, T; Agovino, M; Athilat, S; Lee Argov, EJ; Rodriguez, CB; Tehranifar, P; Terry, MB; Wei, Y1
Borad, MJ; Brusselaers, N; Harmsen, WS; Marcano-Bonilla, L; Patel, T; Petersen, GM; Roberts, LR; Sadr-Azodi, O; Schleck, CD; Therneau, TM1
Gao, B; Gao, W; Ji, Q; Wan, H; Xu, F; Zhang, X; Zhou, R1
Aoki, T; Arai, J; Arai, M; Fujishiro, M; Hasatani, K; Hayakawa, Y; Honda, T; Ikeya, T; Ishibashi, R; Kawahara, T; Kiyotoki, S; Niikura, R; Nishida, T; Ooki, D; Sumiyoshi, T; Suzuki, N; Tsuji, Y; Yamamichi, N; Yoshida, N1
Aleotti, F; Archibugi, L; Arcidiacono, PG; Belfiori, G; Capurso, G; Costamagna, G; Crippa, S; dell'Anna, G; Falconi, M; Gasbarrini, A; Larghi, A; Mariani, A; Nista, E; Petrone, MC; Schepis, T; Tacelli, M; Zaccari, P1
Jing, Y; Kong, P; Sun, Y; Zhou, C; Zhuang, J; Zu, J1
Boiani, NF; Borrely, SI; Garcia, VSG; Silva, TT; Tominaga, FK1
Morrison, FJ; Su, M; Turchin, A1
Attakora, J; Donkoh, IE; Ephraim, RKD; Essuman, G; Okyere, I; Okyere, P; Serwaa, D1
Alwafi, H; Blais, JE; Chan, EW; Cheung, KS; Leung, WK; Shami, JJP; Wan, E; Wei, Y; Wong, CKH; Wong, ICK; Wong, MCS; Yan, VKC1
Chan, KE; Chee, D; Fu, CE; Goh, XL; Huang, DQ; Kim, BK; Lee, SW; Lim, WH; Loomba, R; Muthiah, MD; Ng, CH; Nguyen, MH; Syn, N; Tamaki, N; Tan, C; Tan, DJH; Tan, EX; Xiao, J; Yong, JN; Zeng, RW1
Broder, JC; Ernst, ME; Espinoza, S; Gibbs, P; Lockery, JE; Loomans-Kropp, HA; Orchard, SG; Polekhina, G; Wolfe, R; Woods, RL; Zoungas, S1
Burns, A; Hartman, Y; Hunter, JB; Killeen, DE; Lora Gonzalez, MA; Manickavel, S; Walsh, E; Warram, J1
Andreassen, BK; Botteri, E; Löfling, LL; Støer, NC; Ursin, G1
Aminizadeh, E; Büchler, MW; Chang, DH; Golriz, M; Khajeh, E; Klotz, R; Longerich, T; Mehrabi, A; Merle, U; Moghadam, AD; Ramouz, A; Springfeld, C1
Li, H; Li, X; Yang, F; Zhang, L; Zhao, R1

Reviews

37 review(s) available for metformin and aspirin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
New strategies in the development of anti-atherosclerotic drugs.
    Artery, 1980, Volume: 8, Issue:6

    Topics: 4-Aminobenzoic Acid; Animals; Arteriosclerosis; Aspirin; Coronary Disease; Fatty Acids, Nonesterified; Hepatomegaly; Humans; Hydrogen Peroxide; Hypolipoproteinemias; Lovastatin; Male; Metformin; Microbodies; Naphthalenes; Oligopeptides; para-Aminobenzoates; Platelet Aggregation; Rats

1980
What can the clinician do to improve implantation?
    Reproductive biomedicine online, 2006, Volume: 13, Issue:6

    Topics: Aromatase Inhibitors; Ascorbic Acid; Aspirin; Embryo Implantation; Embryo Transfer; Enzyme Inhibitors; Female; Glucocorticoids; Gonadotropin-Releasing Hormone; Humans; Hypoglycemic Agents; Metformin; Nitric Oxide Donors; Ovulation Induction; Patient Selection; Pregnancy; Progesterone; Reproductive Techniques, Assisted

2006
Non-surgical interventions for threatened and recurrent miscarriages.
    Singapore medical journal, 2007, Volume: 48, Issue:12

    Topics: Abortion, Habitual; Abortion, Threatened; Antiphospholipid Syndrome; Aspirin; Bed Rest; Chorionic Gonadotropin; Education, Medical, Continuing; Evidence-Based Medicine; Female; Gestational Age; Heparin; Humans; Incidence; Metformin; Monitoring, Physiologic; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Outcome; Prenatal Diagnosis; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Singapore

2007
Pretreatments before the induction of ovulation in assisted reproduction technologies: evidence-based medicine in 2007.
    Annals of the New York Academy of Sciences, 2008, Volume: 1127

    Topics: Adrenal Cortex Hormones; Aspirin; Contraceptives, Oral; Evidence-Based Medicine; Female; Fertilization in Vitro; Growth Hormone; Humans; Infertility; Male; Metformin; Ovulation; Ovulation Induction; Pregnancy; Randomized Controlled Trials as Topic; Reproductive Techniques, Assisted

2008
Cancer prevention by targeting angiogenesis.
    Nature reviews. Clinical oncology, 2012, Volume: 9, Issue:9

    Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Autophagy; Cellular Senescence; Chemoprevention; Disease Progression; Fenretinide; Humans; Hypoglycemic Agents; Inflammation; Metformin; Neoplasms; Polyphenols

2012
Hiding in plain view: the potential for commonly used drugs to reduce breast cancer mortality.
    Breast cancer research : BCR, 2012, Dec-10, Volume: 14, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Breast Neoplasms; Digoxin; Drug Repositioning; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Off-Label Use

2012
Prevention and intervention trials for colorectal cancer.
    Japanese journal of clinical oncology, 2013, Volume: 43, Issue:7

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents; Aspirin; Clinical Trials as Topic; Colorectal Neoplasms; Disease Models, Animal; Evidence-Based Medicine; Fatty Acids, Omega-3; Humans; Hypoglycemic Agents; Japan; Lactoferrin; Metformin; Molecular Targeted Therapy; Prevalence; Primary Prevention; Randomized Controlled Trials as Topic

2013
Beyond aspirin-cancer prevention with statins, metformin and bisphosphonates.
    Nature reviews. Clinical oncology, 2013, Volume: 10, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Density Conservation Agents; Diphosphonates; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Neoplasms

2013
Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment.
    Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:4

    Topics: AMP-Activated Protein Kinases; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Repositioning; Humans; Hypoglycemic Agents; Inflammation; Metformin; Pancreatic Neoplasms; TOR Serine-Threonine Kinases

2014
AMPK at the nexus of energetics and aging.
    Cell metabolism, 2014, Jul-01, Volume: 20, Issue:1

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Aspirin; Energy Metabolism; Humans; Metabolic Diseases; Metformin; Mitochondria; Neoplasms; Resveratrol; Stilbenes

2014
Blind Snipers: Relevant Off Target Effects of Non-chemotherapeutic Agents in Oncology: Review of the Literature.
    Reviews on recent clinical trials, 2014, Volume: 9, Issue:2

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Glycosides; Humans; Hypoglycemic Agents; Metformin; Neoplasms; Psychotropic Drugs

2014
Combined cancer therapy with non-conventional drugs: all roads lead to AMPK.
    Mini reviews in medicinal chemistry, 2014, Volume: 14, Issue:8

    Topics: AMP-Activated Protein Kinases; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Cell Line, Tumor; Cell Proliferation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Neoplasms

2014
Koschei the immortal and anti-aging drugs.
    Cell death & disease, 2014, Dec-04, Volume: 5

    Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Caloric Restriction; Exercise; Folklore; Gene Expression; Glucose; Humans; Insulin Resistance; Longevity; Metformin; Propranolol; Russia; Sirolimus; TOR Serine-Threonine Kinases

2014
Update on breast cancer risk prediction and prevention.
    Current opinion in obstetrics & gynecology, 2015, Volume: 27, Issue:1

    Topics: Age of Onset; Aromatase Inhibitors; Aspirin; Biomarkers, Tumor; Breast Neoplasms; Diphosphonates; Female; Humans; Metformin; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome

2015
The Role of Aspirin, Vitamin D, Exercise, Diet, Statins, and Metformin in the Prevention and Treatment of Colorectal Cancer.
    Current treatment options in oncology, 2015, Volume: 16, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemoprevention; Colorectal Neoplasms; Diet; Exercise; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Observational Studies as Topic; Risk Assessment; Risk Reduction Behavior; Vitamin D

2015
Repurposing Drugs for Cancer Prevention.
    Current topics in medicinal chemistry, 2016, Volume: 16, Issue:19

    Topics: Anticarcinogenic Agents; Aspirin; Drug Repositioning; Humans; Metformin; Neoplasms; Pioglitazone; Thiazolidinediones

2016
An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs.
    Current topics in medicinal chemistry, 2016, Volume: 16, Issue:19

    Topics: Antineoplastic Agents; Aspirin; Digoxin; Diphosphonates; Drug Approval; Drug Discovery; Drug Repositioning; Humans; Itraconazole; Metformin; Nelfinavir; Thalidomide

2016
Hereditary cancer syndromes as model systems for chemopreventive agent development.
    Seminars in oncology, 2016, Volume: 43, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Adenomatous Polyposis Coli; Adenosine Triphosphatases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Chemoprevention; Colorectal Neoplasms, Hereditary Nonpolyposis; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; DNA Repair Enzymes; DNA-Binding Proteins; Drug Discovery; Female; Genes, APC; Genes, BRCA1; Genes, BRCA2; Hereditary Breast and Ovarian Cancer Syndrome; Humans; Hypoglycemic Agents; Li-Fraumeni Syndrome; Metformin; Mismatch Repair Endonuclease PMS2; Mutation; MutL Protein Homolog 1; MutS Homolog 2 Protein; Nuclear Proteins; Penetrance; Poly(ADP-ribose) Polymerase Inhibitors; Selective Estrogen Receptor Modulators; Tumor Suppressor Protein p53

2016
Finding New Tricks for Old Drugs: Tumoricidal Activity of Non-Traditional Antitumor Drugs.
    AAPS PharmSciTech, 2016, Volume: 17, Issue:3

    Topics: Animals; Antineoplastic Agents; Aspirin; Clinical Trials as Topic; Flavonoids; Humans; Metformin; Neoplasms; Retrospective Studies

2016
Common medications and prostate cancer mortality: a review.
    World journal of urology, 2017, Volume: 35, Issue:6

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metformin; Middle Aged; Nonprescription Drugs; Observational Studies as Topic; Prescription Drugs; Prostatic Neoplasms; Survival Analysis

2017
The Role of Common Pharmaceutical Agents on the Prevention and Treatment of Pancreatic Cancer.
    Gut and liver, 2016, Sep-15, Volume: 10, Issue:5

    Topics: Adrenergic beta-Antagonists; Anticarcinogenic Agents; Antineoplastic Agents; Aspirin; Dipeptidyl-Peptidase IV Inhibitors; Diphosphonates; Drug Repositioning; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Pancreatic Neoplasms

2016
Aspirin in pancreatic cancer: chemopreventive effects and therapeutic potentials.
    Biochimica et biophysica acta, 2016, Volume: 1866, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Aspirin; Cancer Pain; Humans; Metformin; Pancreatic Neoplasms

2016
Prevention and management of ovarian hyperstimulation syndrome.
    Thrombosis research, 2017, Volume: 151 Suppl 1

    Topics: Aspirin; Calcium Gluconate; Cyclooxygenase Inhibitors; Disease Management; Dopamine Agonists; Female; Gonadotropin-Releasing Hormone; Humans; Hypoglycemic Agents; Metformin; Ovarian Hyperstimulation Syndrome; Ovulation Induction

2017
Potentiating the effects of radiotherapy in rectal cancer: the role of aspirin, statins and metformin as adjuncts to therapy.
    British journal of cancer, 2017, Jul-11, Volume: 117, Issue:2

    Topics: Aspirin; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metformin; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Radiation Tolerance; Rectal Neoplasms; Risk Factors

2017
Preventing Lethal Prostate Cancer with Diet, Supplements, and Rx: Heart Healthy Continues to Be Prostate Healthy and "First Do No Harm" Part I.
    Current urology reports, 2018, Oct-27, Volume: 19, Issue:12

    Topics: Aspirin; Cardiovascular Diseases; Diet; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Style; Male; Metformin; Obesity; Prospective Studies; Prostatic Neoplasms; Risk Reduction Behavior

2018
Prospects of Pharmacological Interventions to Organismal Aging.
    Biomolecular concepts, 2018, Dec-31, Volume: 9, Issue:1

    Topics: Aging; Animals; Aspirin; Growth Hormone; Humans; Metformin; Resveratrol; Signal Transduction; TOR Serine-Threonine Kinases

2018
Common medications and survival in women with ovarian cancer: A systematic review and meta-analysis.
    Gynecologic oncology, 2020, Volume: 157, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Ovarian Neoplasms; Risk Factors; Survival Analysis

2020
Preventing Lethal Prostate Cancer with Diet, Supplements, and Rx: Heart Healthy Continues to Be Prostate Healthy and "First Do No Harm" Part III.
    Current urology reports, 2020, May-04, Volume: 21, Issue:5

    Topics: Adult; Aspirin; Cardiovascular Diseases; Child; Diet; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Style; Male; Metformin; Obesity; Prostatic Neoplasms

2020
Therapeutic aspects of AMPK in breast cancer: Progress, challenges, and future directions.
    Biochimica et biophysica acta. Reviews on cancer, 2020, Volume: 1874, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Aspirin; Biological Products; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Clinical Trials as Topic; Disease Models, Animal; Disease Progression; Enzyme Activators; Female; Humans; Metformin; Phosphorylation; Signal Transduction; Sorafenib; Treatment Outcome

2020
The impact of metformin and aspirin on T-cell mediated inflammation: A systematic review of in vitro and in vivo findings.
    Life sciences, 2020, Aug-15, Volume: 255

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Inflammation; Metformin; T-Lymphocytes

2020
Current Status of Chemoprevention in Barrett's Esophagus.
    Gastrointestinal endoscopy clinics of North America, 2021, Volume: 31, Issue:1

    Topics: Adenocarcinoma; Aspirin; Barrett Esophagus; Chemoprevention; Drug Therapy, Combination; Esophageal Neoplasms; Hormone Replacement Therapy; Humans; Metformin; Proton Pump Inhibitors

2021
The effect of concomitant use of statins, NSAIDs, low-dose aspirin, metformin and beta-blockers on outcomes in patients receiving immune checkpoint inhibitors: a systematic review and meta-analysis.
    Oncoimmunology, 2021, Volume: 10, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immune Checkpoint Inhibitors; Metformin

2021
AMPK activators for the prevention and treatment of neurodegenerative diseases.
    Expert opinion on drug metabolism & toxicology, 2021, Volume: 17, Issue:10

    Topics: AMP-Activated Protein Kinases; Animals; Aspirin; Enzyme Activators; Humans; Metformin; Momordica charantia; Neurodegenerative Diseases; Neuroprotective Agents

2021
Aspirin, metformin, and statin use on the risk of gastric cancer: A nationwide population-based cohort study in Korea with systematic review and meta-analysis.
    Cancer medicine, 2022, Volume: 11, Issue:4

    Topics: Aspirin; Cohort Studies; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Republic of Korea; Stomach Neoplasms

2022
Meta-analysis: Chemoprevention of hepatocellular carcinoma with statins, aspirin and metformin.
    Alimentary pharmacology & therapeutics, 2023, Volume: 57, Issue:6

    Topics: Aspirin; Carcinoma, Hepatocellular; Chemoprevention; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Metformin

2023
Impact of concomitant medications on the efficacy of immune checkpoint inhibitors: an umbrella review.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Analgesics, Opioid; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Esophageal Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immune Checkpoint Inhibitors; Kidney Neoplasms; Liver Neoplasms; Melanoma; Meta-Analysis as Topic; Metformin; Steroids; Systematic Reviews as Topic

2023

Trials

9 trial(s) available for metformin and aspirin

ArticleYear
The ADDITION-Cambridge trial protocol: a cluster -- randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients.
    BMC public health, 2009, May-12, Volume: 9

    Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Early Diagnosis; Humans; Hypoglycemic Agents; Mass Screening; Metformin; Middle Aged; Sodium Chloride Symporter Inhibitors

2009
Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: the Microalbuminuria Education and Medication Optimisation (MEMO) study.
    Diabetes research and clinical practice, 2011, Volume: 93, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Antihypertensive Agents; Aspirin; Blood Pressure; Cholesterol; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Male; Metformin; Middle Aged; Risk Factors

2011
Acetylsalicylic acid therapy: influence of metformin use and other variables on urinary 11-dehydrothromboxane B2 levels.
    Clinica chimica acta; international journal of clinical chemistry, 2014, Feb-15, Volume: 429

    Topics: Aspirin; Biological Transport; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Hypoglycemic Agents; Insulin Resistance; Intestinal Absorption; Male; Metformin; Middle Aged; Oxidative Stress; Risk Factors; Thromboxane B2

2014
Combined effect of metformin with ascorbic acid versus acetyl salicylic acid on diabetes-related cardiovascular complication; a 12-month single blind multicenter randomized control trial.
    Cardiovascular diabetology, 2017, 08-14, Volume: 16, Issue:1

    Topics: Adult; Ascorbic Acid; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Single-Blind Method

2017
Effect of Aspirin on Cancer Chemoprevention in Japanese Patients With Type 2 Diabetes: 10-Year Observational Follow-up of a Randomized Controlled Trial.
    Diabetes care, 2018, Volume: 41, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiovascular Diseases; Chemoprevention; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Incidence; Japan; Male; Metformin; Middle Aged; Neoplasms

2018
The ASAMET trial: a randomized, phase II, double-blind, placebo-controlled, multicenter, 2 × 2 factorial biomarker study of tertiary prevention with low-dose aspirin and metformin in stage I-III colorectal cancer patients.
    BMC cancer, 2018, Dec-04, Volume: 18, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Biomarkers, Tumor; Colorectal Neoplasms; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Follow-Up Studies; Humans; Hypoglycemic Agents; Metformin; Tertiary Prevention

2018
The efficacy of aspirin and metformin combination therapy in patients with rectal aberrant crypt foci: a double-blinded randomized controlled trial.
    BMC cancer, 2020, Oct-29, Volume: 20, Issue:1

    Topics: Aberrant Crypt Foci; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Double-Blind Method; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Metformin; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic

2020
Efficacy and safety of alogliptin versus acarbose in Chinese type 2 diabetes patients with high cardiovascular risk or coronary heart disease treated with aspirin and inadequately controlled with metformin monotherapy or drug-naive: A multicentre, randomi
    Diabetes, obesity & metabolism, 2022, Volume: 24, Issue:6

    Topics: Acarbose; Adult; Aspirin; Coronary Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Glycated Hemoglobin; Heart Disease Risk Factors; Humans; Hypoglycemic Agents; Metformin; Piperidines; Prospective Studies; Treatment Outcome; Uracil

2022
Association of metformin, aspirin, and cancer incidence with mortality risk in adults with diabetes.
    JNCI cancer spectrum, 2023, 03-01, Volume: 7, Issue:2

    Topics: Aged; Aspirin; Diabetes Mellitus, Type 2; Humans; Incidence; Metformin; Neoplasms

2023

Other Studies

79 other study(ies) available for metformin and aspirin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Novel potent antiplatelet thrombotic agent derived from biguanide for ischemic stroke.
    European journal of medicinal chemistry, 2020, Aug-15, Volume: 200

    Topics: Administration, Oral; Animals; Biguanides; Brain Ischemia; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Stroke; Structure-Activity Relationship; Thrombosis

2020
From the Food and Drug Administration.
    JAMA, 1993, Dec-08, Volume: 270, Issue:22

    Topics: Aspirin; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Labeling; Drugs, Investigational; Heart Diseases; Humans; Metformin; Product Surveillance, Postmarketing; United States; United States Food and Drug Administration

1993
Diabetes mellitus with left transverse sinus thrombosis and right transverse sinus aplasia.
    Diabetes research and clinical practice, 2001, Volume: 51, Issue:1

    Topics: Aged; Aspirin; Cerebral Angiography; Cranial Sinuses; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diet, Diabetic; Female; Fibrinolytic Agents; Headache; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Metformin; Sinus Thrombosis, Intracranial; Ticlopidine; Tomography, X-Ray Computed; Urokinase-Type Plasminogen Activator

2001
Management of hyperglycaemia in the patient with acute myocardial infarction.
    Diabetic medicine : a journal of the British Diabetic Association, 2003, Volume: 20 Suppl 3

    Topics: Aspirin; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Metformin; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Thrombolytic Therapy

2003
[Stroke is not equal to stroke. Keep track of the causes].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adult; Antihypertensive Agents; Aspirin; Carotid Artery, Common; Carotid Artery, External; Carotid Stenosis; Diabetes Mellitus, Type 2; Echocardiography; Echocardiography, Doppler; Electrocardiography; Female; Fibrinolytic Agents; Heart Aneurysm; Heart Diseases; Humans; Hypertension; Hypoglycemic Agents; Intracranial Embolism; Male; Metformin; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Thrombosis; Ultrasonography, Doppler, Color

2003
STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation.
    International journal of clinical pharmacology and therapeutics, 2008, Volume: 46, Issue:2

    Topics: Abbreviations as Topic; Age Factors; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bendroflumethiazide; Clopidogrel; Delphi Technique; Digoxin; Diuretics; Drug Prescriptions; Drug Therapy; Drug Utilization Review; Drug-Related Side Effects and Adverse Reactions; Glomerular Filtration Rate; Health Services for the Aged; Humans; Ireland; Metformin; Practice Patterns, Physicians'; Reproducibility of Results; Risk Factors; Ticlopidine; Time Factors; United Kingdom

2008
Adjuncts for ovarian stimulation: when do we adopt "orphan indications" for approved drugs?
    Fertility and sterility, 2009, Volume: 92, Issue:1

    Topics: Androgens; Aspirin; Contraceptives, Oral; Dopamine Agonists; Estrogens; Female; Fertilization in Vitro; Human Growth Hormone; Humans; Leuprolide; Metformin; Orphan Drug Production; Ovulation Induction; Polycystic Ovary Syndrome

2009
Treatment of type 2 diabetes and outcomes in patients with heart failure: a nested case-control study from the U.K. General Practice Research Database.
    Diabetes care, 2010, Volume: 33, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Case-Control Studies; Diabetes Mellitus, Type 2; Digoxin; Female; Heart Failure; Humans; Hypoglycemic Agents; Male; Metformin; United Kingdom

2010
Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes.
    Diabetologia, 2010, Volume: 53, Issue:10

    Topics: Angiotensin Receptor Antagonists; Aspirin; Cell Count; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, Reducing; Endothelial Cells; Exercise Therapy; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukocytes, Mononuclear; Life Style; Male; Metformin; Stem Cells; Treatment Outcome

2010
What are these lesions that spread from the lips. Fixed drug eruption.
    JAAPA : official journal of the American Academy of Physician Assistants, 2010, Volume: 23, Issue:10

    Topics: Adult; Aspirin; Biopsy, Needle; Drug Eruptions; Female; Humans; Hypoglycemic Agents; Metformin; Nonprescription Drugs

2010
Effect of concomitant statin, metformin, or aspirin on rituximab treatment for diffuse large B-cell lymphoma.
    Leukemia & lymphoma, 2011, Volume: 52, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Lymphoma, Large B-Cell, Diffuse; Male; Metformin; Middle Aged; Prednisone; Rituximab; Treatment Outcome; Vincristine; Young Adult

2011
Effect of aspirin on the expression of hepatocyte NF-κB and serum TNF-α in streptozotocin-induced type 2 diabetic rats.
    Journal of Korean medical science, 2011, Volume: 26, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver; Male; Metformin; NF-kappa B; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2011
Multiple cerebral infarctions related to famotidine-induced eosinophilia.
    Journal of neurology, 2012, Volume: 259, Issue:10

    Topics: Acarbose; Adrenergic alpha-1 Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Cerebral Infarction; Diabetes Mellitus, Type 2; Diffusion Magnetic Resonance Imaging; Drug-Related Side Effects and Adverse Reactions; Eosinophilia; Famotidine; Humans; Hypertension; Hypoglycemic Agents; Labetalol; Male; Metformin; Middle Aged; Nifedipine; Peptic Ulcer; Prazosin; Sulfonylurea Compounds

2012
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2012, Volume: 23, Issue:8

    Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6

2012
Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling.
    Aging, 2012, Volume: 4, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Aspirin; Ataxia Telangiectasia Mutated Proteins; Berberine; Cell Cycle Proteins; Cell Line, Tumor; Cellular Senescence; Cholecalciferol; Deoxyglucose; DNA Damage; DNA-Binding Proteins; Down-Regulation; Enzyme Activation; Flow Cytometry; Histones; Humans; Laser Scanning Cytometry; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Oxidative Stress; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Resveratrol; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins

2012
Prevention of colorectal adenomas.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2015, Volume: 17 Suppl 1

    Topics: Adenoma; Aspirin; Colorectal Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Ligands; Lignin; Metformin; Phytoestrogens; Silymarin

2015
The risk of prostate cancer for men on aspirin, statin or antidiabetic medications.
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:6

    Topics: Aspirin; Cohort Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Metformin; Middle Aged; Prostatic Neoplasms; Retrospective Studies; Risk Factors; Sweden

2015
Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity.
    The Biochemical journal, 2015, May-15, Volume: 468, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Aspirin; Cardiotonic Agents; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Synergism; Enzyme Activation; Hepatocytes; Humans; Hypoglycemic Agents; Insulin Resistance; Lipogenesis; Liver; Male; Metformin; Mice; Mice, Inbred C57BL

2015
Impacts of metformin and aspirin on life history features and longevity of crickets: trade-offs versus cost-free life extension?
    Age (Dordrecht, Netherlands), 2015, Volume: 37, Issue:2

    Topics: Animals; Aspirin; Female; Gryllidae; Longevity; Male; Metformin

2015
Stroke mimicking relapse in a patient with CLIPPERS syndrome.
    Acta neurologica Belgica, 2015, Volume: 115, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aspirin; Brain Stem; Encephalomyelitis; Gadolinium; Humans; Hypoglycemic Agents; Inflammation; Magnetic Resonance Imaging; Male; Metformin; Middle Aged; Recurrence; Simvastatin; Stroke

2015
Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.
    Oncotarget, 2015, Aug-28, Volume: 6, Issue:25

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Aspirin; Bcl-2-Like Protein 11; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Survival; Cyclin D1; Female; Humans; Membrane Proteins; Metformin; Mice; Mice, SCID; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Wound Healing

2015
Are metformin, statin and aspirin use still associated with overall mortality among colorectal cancer patients with diabetes if adjusted for one another?
    British journal of cancer, 2015, Jul-28, Volume: 113, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Colorectal Neoplasms; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Metformin; Middle Aged; Registries; Risk Factors; Survival Analysis

2015
Transcriptomic analysis of pancreatic cancer cells in response to metformin and aspirin: an implication of synergy.
    Scientific reports, 2015, Aug-21, Volume: 5

    Topics: Aspirin; Cell Line, Tumor; Down-Regulation; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Metformin; Pancreatic Neoplasms; Reproducibility of Results; RNA, Messenger; Signal Transduction

2015
[Impact of sitagliptin on aspirin resistance in patients with Type 2 diabetes mellitus].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2015, Volume: 40, Issue:11

    Topics: Aspirin; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Drug Resistance; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Metformin; Oxidative Stress; Sitagliptin Phosphate

2015
Aspirin and atenolol enhance metformin activity against breast cancer by targeting both neoplastic and microenvironment cells.
    Scientific reports, 2016, Jan-05, Volume: 6

    Topics: Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Atenolol; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Electron Transport Complex I; Female; Humans; Metformin; NAD; Neoplasm Metastasis; Stem Cells; Triple Negative Breast Neoplasms; Tumor Burden; Tumor Microenvironment; Xenograft Model Antitumor Assays

2016
Effects of Statin, Aspirin or Metformin Use on Recurrence-Free and Overall Survival in Patients with Biliary Tract Cancer.
    Hepato-gastroenterology, 2015, Volume: 62, Issue:139

    Topics: Aged; Aspirin; Biliary Tract Neoplasms; Cardiovascular Agents; Comorbidity; Disease Progression; Disease-Free Survival; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Kaplan-Meier Estimate; Male; Metformin; Multivariate Analysis; Neoplasm Recurrence, Local; Proportional Hazards Models; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome

2015
Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos.
    Journal of assisted reproduction and genetics, 2016, Volume: 33, Issue:8

    Topics: AMP-Activated Protein Kinases; Animals; Aspirin; Dietary Supplements; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Fertility Agents; Indoles; Metformin; Mice; Sorbitol; Stem Cells; Stress, Physiological

2016
Dipeptidyl Peptidase-4 Inhibitor-Associated Risk of Bleeding: An Evaluation of Reported Adverse Events.
    The Annals of pharmacotherapy, 2017, Volume: 51, Issue:7

    Topics: Adverse Drug Reaction Reporting Systems; Aspirin; Clopidogrel; Dipeptidyl-Peptidase IV Inhibitors; Hemorrhage; Humans; Hypoglycemic Agents; Metformin; Odds Ratio; Platelet Aggregation Inhibitors; Retrospective Studies; Risk; Ticlopidine

2017
Reducing CV risk in diabetes: An ADA update.
    The Journal of family practice, 2017, Volume: 66, Issue:5

    Topics: Antihypertensive Agents; Aspirin; Benzhydryl Compounds; Cardiovascular Diseases; Contraindications; Creatinine; Diabetes Complications; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Drug Chronotherapy; Ezetimibe; Fenofibrate; Glucosides; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Hypolipidemic Agents; Life Style; Liraglutide; Metformin; Niacin; PCSK9 Inhibitors; Platelet Aggregation Inhibitors; Risk Reduction Behavior; Thiazolidinediones

2017
The effect of rapamycin, NVP-BEZ235, aspirin, and metformin on PI3K/AKT/mTOR signaling pathway of PIK3CA-related overgrowth spectrum (PROS).
    Oncotarget, 2017, Jul-11, Volume: 8, Issue:28

    Topics: Adult; Aspirin; Child, Preschool; Class I Phosphatidylinositol 3-Kinases; DNA Mutational Analysis; Dose-Response Relationship, Drug; Female; Fibroblasts; Genetic Association Studies; Growth Disorders; Humans; Imidazoles; Male; Metformin; Mutation; Phenotype; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinolines; Signal Transduction; TOR Serine-Threonine Kinases

2017
Targeting AMPK, mTOR and β-Catenin by Combined Metformin and Aspirin Therapy in HCC: An Appraisal in Egyptian HCC Patients.
    Molecular diagnosis & therapy, 2018, Volume: 22, Issue:1

    Topics: Adult; AMP-Activated Protein Kinases; Antineoplastic Combined Chemotherapy Protocols; Aspirin; beta Catenin; Carcinoma, Hepatocellular; Cell Survival; Egypt; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; Metformin; Middle Aged; Phosphorylation; TOR Serine-Threonine Kinases; Up-Regulation

2018
Ampholytic starch excipients for high loaded drug formulations: Mechanistic insights.
    International journal of pharmaceutics, 2018, Jan-15, Volume: 535, Issue:1-2

    Topics: Acetaminophen; Aspirin; Drug Compounding; Excipients; Mesalamine; Metformin; Starch; Tablets; Viscosity

2018
Aspirin and metformin exhibit antitumor activity in murine breast cancer.
    Oncology reports, 2018, Volume: 39, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aspirin; Breast Neoplasms; Cell Proliferation; Female; Humans; Hypoglycemic Agents; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; Signal Transduction; Transforming Growth Factor beta; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2018
Pre-clinical effects of metformin and aspirin on the cell lines of different breast cancer subtypes.
    Investigational new drugs, 2018, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Aspirin; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Synergism; Humans; Metformin; Receptors, Estrogen

2018
Comment on "Targeting AMPK, mTOR and β-Catenin by Combined Metformin and Aspirin Therapy in HCC: An Appraisal in Egyptian HCC Patients".
    Molecular diagnosis & therapy, 2018, Volume: 22, Issue:4

    Topics: Aspirin; beta Catenin; Egypt; Humans; Metformin; TOR Serine-Threonine Kinases

2018
Metformin and risk of hepatocellular carcinoma in patients with type 2 diabetes.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:11

    Topics: Aged; Aspirin; Carcinoma, Hepatocellular; Cohort Studies; Databases, Factual; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Incidence; Liver Neoplasms; Male; Metformin; Middle Aged; Propensity Score; Proportional Hazards Models; Risk Factors; Risk Reduction Behavior; Taiwan

2018
Separation and Analysis of Aspirin and Metformin HCl Using Green Subcritical Water Chromatography.
    Molecules (Basel, Switzerland), 2018, Sep-05, Volume: 23, Issue:9

    Topics: Aspirin; Chromatography, High Pressure Liquid; Metformin

2018
An Irish National Diabetes in Pregnancy Audit: aiming for best outcomes for women with diabetes.
    Diabetic medicine : a journal of the British Diabetic Association, 2020, Volume: 37, Issue:12

    Topics: Abortion, Spontaneous; Adult; Aspirin; Cesarean Section; Clinical Audit; Delivery of Health Care; Delivery, Obstetric; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Fetal Macrosomia; Folic Acid; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Infant, Newborn; Infusion Pumps, Implantable; Insulin; Insulin Infusion Systems; Intensive Care Units, Neonatal; Ireland; Live Birth; Mass Screening; Metformin; Platelet Aggregation Inhibitors; Preconception Care; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome; Premature Birth; Retrospective Studies; Stillbirth; Vitamin B Complex

2020
Comparison of the Neuroprotective Effects of Aspirin, Atorvastatin, Captopril and Metformin in Diabetes Mellitus.
    Biomolecules, 2019, 03-27, Volume: 9, Issue:4

    Topics: Animals; Aspirin; Atorvastatin; Captopril; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Metformin; Neuroprotective Agents; Rats; Rats, Wistar; Streptozocin

2019
Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity
    Mediators of inflammation, 2019, Volume: 2019

    Topics: AC133 Antigen; Antigens, CD34; Aspirin; Atorvastatin; Cells, Cultured; Culture Media, Conditioned; Hematopoietic Stem Cells; Heme Oxygenase-1; Humans; Immunoassay; Isothiocyanates; Leukocytes, Mononuclear; Metformin; Neovascularization, Physiologic; Phenotype; Resveratrol; Sulfoxides

2019
Metformin use and risk of gastric adenocarcinoma in a Swedish population-based cohort study.
    British journal of cancer, 2019, Volume: 121, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diabetes Mellitus; Female; Helicobacter Infections; Helicobacter pylori; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metformin; Middle Aged; Proportional Hazards Models; Risk Factors; Stomach Neoplasms; Sweden

2019
A Decision-Support Software to Improve the Standard Care in Chinese Type 2 Diabetes.
    Journal of diabetes research, 2019, Volume: 2019

    Topics: Antihypertensive Agents; Aspirin; Blood Glucose; Blood Pressure; Cardiovascular Diseases; China; Decision Support Systems, Clinical; Diabetes Mellitus, Type 2; Guideline Adherence; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Quality Improvement; Quality of Health Care; Secondary Prevention; Software

2019
Elevated T-helper 2 cytokine levels in high fat diet-fed C57BL/6 mice are attenuated by short-term 6-week treatment with a combination of low-dose aspirin and metformin.
    Cytokine, 2020, Volume: 128

    Topics: Animals; Aspirin; Cytokines; Drug Therapy, Combination; Glucose Intolerance; Male; Metformin; Mice; Mice, Inbred C57BL; Th1 Cells; Th17 Cells; Th2 Cells

2020
A Triple Combination of Metformin, Acetylsalicylic Acid, and Oseltamivir Phosphate Impacts Tumour Spheroid Viability and Upends Chemoresistance in Triple-Negative Breast Cancer.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Aldehyde Dehydrogenase 1 Family; Antineoplastic Agents; Apoptosis; Aspirin; Breast Neoplasms; CD24 Antigen; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Hyaluronan Receptors; Metformin; Oseltamivir; Retinal Dehydrogenase; Spheroids, Cellular; Tamoxifen; Triple Negative Breast Neoplasms; Tumor Cells, Cultured

2020
Activation of AMP-Activated Protein Kinases Prevents Atrial Fibrillation.
    Journal of cardiovascular translational research, 2021, Volume: 14, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrillation; Atrial Remodeling; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Female; Fibrosis; Heart Rate; Male; Metformin; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Myocytes, Cardiac; Primary Prevention

2021
Drug repurposing for cancer treatments: a well-intentioned, but misguided strategy.
    The Lancet. Oncology, 2020, Volume: 21, Issue:9

    Topics: Aspirin; Drug Repositioning; Humans; Metformin; Neoplasms; Vitamin D

2020
Use of metformin and aspirin is associated with delayed cancer incidence.
    Cancer epidemiology, 2020, Volume: 69

    Topics: Aged; Aged, 80 and over; Aspirin; Delayed Diagnosis; Female; Humans; Incidence; Male; Metformin; Middle Aged; Neoplasms; Retrospective Studies

2020
Association of Aspirin, Metformin, and Statin Use with Gastric Cancer Incidence and Mortality: A Nationwide Cohort Study.
    Cancer prevention research (Philadelphia, Pa.), 2021, Volume: 14, Issue:1

    Topics: Adult; Aged; Aspirin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Metformin; Middle Aged; Mortality; Republic of Korea; Retrospective Studies; Stomach Neoplasms

2021
The Associations of Aspirin, Statins, and Metformin With Lung Cancer Risk and Related Mortality: A Time-Dependent Analysis of Population-Based Nationally Representative Data.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2021, Volume: 16, Issue:1

    Topics: Aspirin; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Neoplasms; Metformin

2021
One Metformin a Day, Keeps Lung Cancer Away! Or Does It?
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2021, Volume: 16, Issue:1

    Topics: Aspirin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Lung Neoplasms; Metformin

2021
The aberrant expression of CD69 on peripheral T-helper cells in diet-induced inflammation is ameliorated by low-dose aspirin and metformin treatment.
    Cellular immunology, 2021, Volume: 363

    Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Disease Models, Animal; Gene Expression; Hypoglycemic Agents; Inflammation; Lectins, C-Type; Male; Metformin; Mice; Mice, Inbred C57BL; T-Lymphocytes, Helper-Inducer

2021
Dashboards to reduce inappropriate prescribing of metformin and aspirin: A quality assurance programme in a primary care sentinel network.
    Primary care diabetes, 2021, Volume: 15, Issue:6

    Topics: Aspirin; Diabetes Mellitus, Type 2; Humans; Inappropriate Prescribing; Metformin; Primary Health Care

2021
Metformin Targets Foxo1 to Control Glucose Homeostasis.
    Biomolecules, 2021, 06-11, Volume: 11, Issue:6

    Topics: Animals; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Forkhead Box Protein O1; Gluconeogenesis; Glucose; Hepatocytes; Homeostasis; Humans; Insulin Resistance; Liver; Male; Metformin; Mice; Mice, Knockout; Middle Aged; Phosphorylation; Signal Transduction; Streptozocin

2021
Population-wide impacts of aspirin, statins, and metformin use on prostate cancer incidence and mortality.
    Scientific reports, 2021, 08-09, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cohort Studies; Health Surveys; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Incidence; Longitudinal Studies; Male; Metformin; Middle Aged; Proportional Hazards Models; Prostatic Neoplasms; Republic of Korea

2021
Chemoprevention of Oesophageal Squamous-Cell Carcinoma and Adenocarcinoma: A Multicentre Retrospective Cohort Study.
    Digestion, 2022, Volume: 103, Issue:3

    Topics: Adenocarcinoma; Aspirin; Case-Control Studies; Chemoprevention; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Proton Pump Inhibitors; Retrospective Studies; Risk Factors

2022
Current regular aspirin use and mammographic breast density: a cross-sectional analysis considering concurrent statin and metformin use.
    Cancer causes & control : CCC, 2022, Volume: 33, Issue:3

    Topics: Adult; Aspirin; Breast Density; Breast Neoplasms; Cross-Sectional Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mammography; Metformin; Middle Aged; Pregnancy; Risk Factors

2022
Aspirin, Statins, Non-aspirin NSAIDs, Metformin, and the Risk of Biliary Cancer: A Swedish Population-Based Cohort Study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2022, 04-01, Volume: 31, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biliary Tract Neoplasms; Cohort Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Risk Factors; Sweden

2022
Chemoprevention for Colorectal Cancers: Are Chemopreventive Effects Different Between Left and Right Sided Colorectal Cancers?
    Digestive diseases and sciences, 2022, Volume: 67, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Metformin; Retrospective Studies

2022
Risk factors for the occurrence of ampullary tumors: A case-control study.
    United European gastroenterology journal, 2022, Volume: 10, Issue:7

    Topics: Adenoma; Ampulla of Vater; Aspirin; Carcinoma; Case-Control Studies; Common Bile Duct Neoplasms; Duodenal Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulins; Metformin; Pancreatic Neoplasms; Proton Pump Inhibitors; Risk Factors

2022
Bioinformatic Data Mining for Candidate Drugs Affecting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) in Cancer Patients.
    Disease markers, 2022, Volume: 2022

    Topics: Androgen Antagonists; Androgens; Aspirin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Caspases; Computational Biology; Data Mining; Humans; Leukocytes, Mononuclear; Metformin; Multiple Myeloma; Progesterone; Thrombin; Vitamin D

2022
Acute and chronic ecotoxicological effects of pharmaceuticals and their mixtures in Daphnia similis.
    Chemosphere, 2022, Volume: 309, Issue:Pt 1

    Topics: Animals; Anti-Bacterial Agents; Aspirin; Ciprofloxacin; Daphnia; Fluoxetine; Hypoglycemic Agents; Metformin; Pharmaceutical Preparations; Water; Water Pollutants, Chemical

2022
COVID-19 outcomes in patients taking cardioprotective medications.
    PloS one, 2022, Volume: 17, Issue:10

    Topics: Aspirin; COVID-19; COVID-19 Drug Treatment; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Retrospective Studies; SARS-CoV-2

2022
Conservative therapy is associated with worse clinical features and biochemical derangements than renal replacement therapy: a retrospective study in Kumasi, Ghana.
    BMC nephrology, 2022, 10-26, Volume: 23, Issue:1

    Topics: Adult; Aspirin; Bisoprolol; Conservative Treatment; Furosemide; Ghana; Humans; Irbesartan; Kidney Failure, Chronic; Lisinopril; Metformin; Middle Aged; Nifedipine; Ranitidine; Renal Replacement Therapy; Retrospective Studies; Sodium

2022
Low-dose aspirin does not lower the risk of colorectal cancer in patients with type 2 diabetes taking metformin.
    Journal of internal medicine, 2023, Volume: 293, Issue:3

    Topics: Adult; Aspirin; Cohort Studies; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin

2023
Metformin Reduces Tumor Growth in a Murine Flank Schwannoma Model.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2023, 10-01, Volume: 44, Issue:9

    Topics: Animals; Aspirin; Metformin; Mice; Mice, Nude; Neurilemmoma; Neuroma, Acoustic; Rats

2023
Low-dose aspirin, statins, and metformin and survival in patients with breast cancers: a Norwegian population-based cohort study.
    Breast cancer research : BCR, 2023, 08-30, Volume: 25, Issue:1

    Topics: Aspirin; Breast Neoplasms; Cohort Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Norway; Receptors, Estrogen

2023
Association of perioperative use of statins, metformin, and aspirin with recurrence after curative liver resection in patients with hepatocellular carcinoma: A propensity score matching analysis.
    Cancer medicine, 2023, Volume: 12, Issue:19

    Topics: Aspirin; Carcinoma, Hepatocellular; Hepatectomy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Metformin; Propensity Score; Retrospective Studies

2023