metformin has been researched along with ascorbic acid in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 14 (63.64) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ananthakrishnan, R; Jayamurthy, P; Krishnan, SL; Madhukrishnan, M; Manojkumar, TK; Neethu, S; Prabha, B; Radhakrishnan, KV; Rameshkumar, KB; Sherin, DR | 1 |
| Comar, KM; Sterling, RK | 1 |
| Boomsma, CM; Macklon, NS | 1 |
| Adeneye, AA; Agbaje, EO; Amole, OO; Elias, SO; Izegbu, MC | 1 |
| Aragão, DM; da Costa, JC; Garcia, RM; Guarize, L; Lanini, J; Scio, E | 1 |
| Bansod, K; Bhutada, P; Dixit, P; Mundhada, D; Mundhada, Y; Patil, S; Tawari, S; Umathe, S | 1 |
| Bagul, PK; Banerjee, SK; Bastia, T; Chakravarty, S; Madhusudana, K; Matapally, S; Middela, H; Padiya, R; Reddy, BR | 1 |
| Kuncha, M; Putcha, UK; Sahu, BD; Sistla, R | 1 |
| Abdul, MIM; Baig, MR; Gillani, SW; Sulaiman, SAS | 1 |
| Kumar, M; Nayak, PK; Shivavedi, N; Tej, GNVC | 1 |
| Aa, AB; Ga, A; Om, J; Ts, E | 1 |
| El-Aal, AA; El-Ghffar, EAA; Ghali, AA; Sirdah, MM; Zughbur, MR | 1 |
| An, H; An, X; Chen, Y; Dai, X; Guan, S; Huang, B; Huang, Q; Liang, L; Lu, M; Lu, X; Nie, H; Wang, H; Wang, J; Wang, Z; Zhang, H | 1 |
| Abraham, AG; Blake, A; Blancher, C; Burns, A; D'Costa, Z; Eyres, M; Goldin, R; Hubert, A; Hughes, D; Hughes, S; Jones, S; Lanfredini, S; Maughan, T; Mukherjee, S; O'Neill, E; Sabbagh, A; Schuh, A; Silva, M; Soonawalla, Z; Thapa, A; Vavoulis, D; Verrill, C; Willenbrock, F; Xu, H | 1 |
| Ahmed, MM; Al-Mokaddem, AK; Ali, MA; Aljuaydi, SH; Khalil, HMA; Khalil, MM | 1 |
| He, P; Li, Z; Long, Y; Peng, L; Qiu, J; Shen, W; Shi, X; Yang, T; Zhang, B; Zhang, X | 1 |
| Bagatini, MD; Barcelos, RCS; Benvegnú, DM; Bolzan, RC; da Silva Rosa Bonadiman, B; da Silva, GB; Dos Santos, D; Flores, ÉMM; Manica, A; Manica, D; Sandri, G; Suthovski, G; Tomazoni, F | 1 |
3 review(s) available for metformin and ascorbic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Review article: Drug therapy for non-alcoholic fatty liver disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Ascorbic Acid; Betaine; Cholagogues and Choleretics; Enzyme Inhibitors; Fatty Liver; Humans; Hypoglycemic Agents; Lipotropic Agents; Metformin; Pentoxifylline; Probucol; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E | 2006 |
What can the clinician do to improve implantation?
Topics: Aromatase Inhibitors; Ascorbic Acid; Aspirin; Embryo Implantation; Embryo Transfer; Enzyme Inhibitors; Female; Glucocorticoids; Gonadotropin-Releasing Hormone; Humans; Hypoglycemic Agents; Metformin; Nitric Oxide Donors; Ovulation Induction; Patient Selection; Pregnancy; Progesterone; Reproductive Techniques, Assisted | 2006 |
2 trial(s) available for metformin and ascorbic acid
| Article | Year |
|---|---|
Combined effect of metformin with ascorbic acid versus acetyl salicylic acid on diabetes-related cardiovascular complication; a 12-month single blind multicenter randomized control trial.
Topics: Adult; Ascorbic Acid; Aspirin; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Single-Blind Method | 2017 |
The effect of vitamin C and/or E supplementations on type 2 diabetic adult males under metformin treatment: A single-blinded randomized controlled clinical trial.
Topics: Adult; Antioxidants; Ascorbic Acid; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Dietary Supplements; Drug Synergism; Female; Follow-Up Studies; Glycated Hemoglobin; Hematologic Tests; Humans; Hypoglycemic Agents; Insulin Resistance; Kidney Function Tests; Lipids; Liver Function Tests; Male; Metformin; Middle Aged; Middle East; Oxidative Stress; Prognosis; Single-Blind Method; Vitamin E; Vitamins | 2018 |
17 other study(ies) available for metformin and ascorbic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair.
Topics: alpha-Glucosidases; Binding Sites; Cell Line; Cell Survival; Diabetes Mellitus, Type 2; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Molecular Dynamics Simulation; Muscle Cells; Myristicaceae; Phytochemicals; Plant Bark; Plant Extracts; Plant Stems; Protein Structure, Tertiary; Resorcinols | 2018 |
Effect of chronic co-administration of metformin and vitamin C on plasma glucose and lipid concentrations in normal rats.
Topics: Administration, Oral; Animals; Ascorbic Acid; Blood Glucose; Body Weight; Drug Therapy, Combination; Hypoglycemic Agents; Lipids; Metformin; Rats; Rats, Wistar; Vitamins | 2007 |
Hypoglycemic effects of Cecropia pachystachya in normal and alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Cecropia Plant; Diabetes Mellitus; Diabetes Mellitus, Type 2; Flavonoids; Free Radical Scavengers; Glucose Tolerance Test; Glucosides; Glyburide; Hypoglycemic Agents; Male; Medicine, Traditional; Metformin; Phenols; Plant Extracts; Rats; Rats, Wistar | 2010 |
Protection of cholinergic and antioxidant system contributes to the effect of berberine ameliorating memory dysfunction in rat model of streptozotocin-induced diabetes.
Topics: Acetylcholine; Administration, Oral; Analysis of Variance; Animals; Antioxidants; Ascorbic Acid; Berberine; Blood Glucose; Body Weight; Brain; Cholinesterase Inhibitors; Cholinesterases; Diabetes Mellitus, Experimental; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Glutathione; Hypoglycemic Agents; Indans; Lipid Peroxidation; Male; Maze Learning; Memory Disorders; Metformin; Piperidines; Rats; Rats, Wistar | 2011 |
Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats.
Topics: Animals; Ascorbic Acid; Blood Glucose; Body Weight; Catalase; Eating; Fructose; Glucose Tolerance Test; Glutathione; Insulin; Insulin Resistance; Liver; Male; Metabolic Syndrome; Metformin; NF-E2-Related Factor 2; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Triglycerides; Uric Acid | 2012 |
Effect of metformin against cisplatin induced acute renal injury in rats: a biochemical and histoarchitectural evaluation.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Cisplatin; Glutathione; Kidney; Kidney Function Tests; Lipid Peroxidation; Male; Metformin; Rats; Rats, Wistar; Reactive Oxygen Species | 2013 |
Metformin and ascorbic acid combination therapy ameliorates type 2 diabetes mellitus and comorbid depression in rats.
Topics: Animals; Ascorbic Acid; Biogenic Monoamines; Blood Glucose; Comorbidity; Corticosterone; Cytokines; Depression; Depressive Disorder; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Therapy, Combination; Insulin; Male; Metformin; Oxidative Stress; Rats; Rats, Inbred Strains | 2017 |
Preliminary phytochemical screening, antioxidant and antihyperglycaemic activity of Moringa oleifera leaf extracts.
Topics: Alloxan; Animals; Antioxidants; Ascorbic Acid; Biphenyl Compounds; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Ethanol; Female; Hypoglycemic Agents; Male; Metformin; Methanol; Moringa oleifera; Picrates; Plant Extracts; Plant Leaves; Rats, Wistar; Solvents; Water | 2017 |
Transcriptome and lipidome profile of human mesenchymal stem cells with reduced senescence and increased trilineage differentiation ability upon drug treatment.
Topics: Ascorbic Acid; Cell Differentiation; Cellular Senescence; Humans; Hypoglycemic Agents; Lipidomics; Mesenchymal Stem Cells; Metformin; Pyrazines; Reverse Transcriptase Inhibitors; Sirolimus; Thiones; Thiophenes; Transcriptome | 2021 |
TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.
Topics: 5-Methylcytosine; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Differentiation; Cell Line, Tumor; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Epigenome; Epigenomics; GATA6 Transcription Factor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Metformin; Mice, Nude; Mice, Transgenic; Pancreatic Neoplasms; Retrospective Studies; Smad4 Protein; Transcription, Genetic; Transcriptome; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2021 |
Differential effects of cancer modifying agents during radiation therapy on Ehrlich solid tumor-bearing mice: A comparative investigation of metformin and ascorbic acid.
Topics: Animals; Ascorbic Acid; Carcinoma, Ehrlich Tumor; Lipid Peroxidation; Metformin; Mice; Neoplasms | 2022 |
Mitochondrial respiration inhibitor enhances the anti-tumor effect of high-dose ascorbic acid in castration-resistant prostate cancer.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Humans; Male; Metformin; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Respiration; TOR Serine-Threonine Kinases | 2023 |
Evaluation of the effects of metformin on antioxidant biomarkers and mineral levels in patients with type II diabetes mellitus: A cross-sectional study.
Topics: Antioxidants; Ascorbic Acid; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Leukocytes, Mononuclear; Metformin; Minerals | 2023 |