Compounds > metformin

metformin and arsenic trioxide

metformin has been researched along with arsenic trioxide in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (88.89)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Flomenberg, N; Goldberg, A; Howell, A; Ko, YH; Lin, Z; Lisanti, MP; Martinez-Outschoorn, UE; Pavlides, S; Pestell, RG; Sotgia, F; Wang, C1
Ling, S; Sun, D; Tian, Y; Wang, L; Yang, X1
Dai, H; Ling, S; Shan, Q; Song, P; Wei, X; Xie, H; Xu, X; Yang, F; Zheng, S; Zhou, L; Zhuo, J1
Chen, K; Feng, T; Ling, S; Liu, J; Liu, P; Shan, Q; Song, P; Xiang, P; Xie, H; Xu, X; Zhang, X; Zheng, S; Zhou, L1
Asik, A; Balcı Okcanoglu, T; Biray Avci, C; Dogan Sigva, ZO; Gunduz, C; Kayabasi, C; Ozmen Yelken, B; Saydam, G; Yılmaz Susluer, S1
Durães, F; Maia, M; Pinto, MMM; Resende, DISP; Sousa, E1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

2 review(s) available for metformin and arsenic trioxide

ArticleYear
Xanthenes in Medicinal Chemistry - Synthetic strategies and biological activities.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Chemistry, Pharmaceutical; Fungi; Humans; Neoplasms; Neuroprotective Agents; Xanthenes

2021
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for metformin and arsenic trioxide

ArticleYear
Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.
    Cancer biology & therapy, 2011, Nov-15, Volume: 12, Issue:10

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Arsenic Trioxide; Arsenicals; Breast Neoplasms; Cell Line, Tumor; Coculture Techniques; Doxorubicin; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Fibroblasts; Fulvestrant; Humans; Hypoglycemic Agents; Intracellular Signaling Peptides and Proteins; Ketone Bodies; Lactic Acid; Metformin; Mitochondria; Oxides; Phosphoric Monoester Hydrolases; Poly(ADP-ribose) Polymerase Inhibitors; Tamoxifen; Tumor Microenvironment

2011
Metformin sensitizes hepatocellular carcinoma to arsenic trioxide-induced apoptosis by downregulating Bcl2 expression.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:4

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Proliferation; Drug Synergism; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Metformin; Oxides; Proto-Oncogene Proteins c-bcl-2

2015
Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1.
    Journal of hematology & oncology, 2017, 02-28, Volume: 10, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Arsenic Trioxide; Arsenicals; Bile Duct Neoplasms; Cell Line, Tumor; Cholangiocarcinoma; Drug Synergism; Heterografts; Humans; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 6; Oxides; p38 Mitogen-Activated Protein Kinases; Signal Transduction

2017
Metformin ameliorates arsenic trioxide hepatotoxicity via inhibiting mitochondrial complex I.
    Cell death & disease, 2017, 11-02, Volume: 8, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line; Chemical and Drug Induced Liver Injury; Electron Transport Complex I; Glucose; Glycolysis; Humans; Leukemia, Myeloid; Male; Metformin; Mice; NAD; Oxidative Phosphorylation; Oxides; Reactive Oxygen Species; Rotenone

2017
Antileukemic effect of paclitaxel in combination with metformin in HL-60 cell line.
    Gene, 2018, Mar-20, Volume: 647

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Drug Therapy, Combination; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Metformin; NF-kappa B; Oxides; Paclitaxel; Signal Transduction

2018
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010