metformin and apigenin

metformin has been researched along with apigenin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Fan, Z; Lu, K; Ma, Y; Pan, G; Xiao, N; Yang, K; Yao, Q; Yu, P; Zhang, Y; Zhao, L; Zhao, X1
Chen, M; Jiang, H; Jin, Z; Ma, Y; Sun, H; Wang, K; Yu, P; Zhang, M; Zhang, Y; Zheng, H1
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Balk, B; Bujok, K; Fromm, MF; Glaeser, H; Mandery, K; Schmidt, I1
Jia, Y; Lee, JH; Lee, SJ; Seo, WD; Wu, C1
Cheng, Y; Hao, T; Liu, Y; Wang, D; Wang, J; Wang, L; Zhang, X1
Feng, JH; Inci, G; Jung, JS; Kang, BG; Kim, CH; Kim, SC; Lee, JY; Lim, SS; Park, SH; Suh, HW; Warkad, MS1
Alahmadi, AA; Alahmadi, BA; Ali, SS; Alzahrani, AA; Arab, RA; El-Shitany, NAE1

Other Studies

8 other study(ies) available for metformin and apigenin

ArticleYear
Total synthesis of 8-(6″-umbelliferyl)-apigenin and its analogs as anti-diabetic reagents.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: 3T3-L1 Cells; Adipocytes; Alkylation; Animals; Apigenin; Chemistry Techniques, Synthetic; Drug Design; Glucose; Hypoglycemic Agents; Mice

2016
New insights into the biological activities of Chrysanthemum morifolium: Natural flavonoids alleviate diabetes by targeting α-glucosidase and the PTP-1B signaling pathway.
    European journal of medicinal chemistry, 2019, Sep-15, Volume: 178

    Topics: Animals; Cell Line, Tumor; Cholesterol; Chrysanthemum; Cricetulus; Diabetes Mellitus, Experimental; Flavonoids; Glucose; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Male; Mice; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Signal Transduction; Streptozocin; Triglycerides

2019
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
Inhibition of hepatic uptake transporters by flavonoids.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, May-12, Volume: 46, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; Apigenin; Atorvastatin; Biological Transport; Flavanones; Flavonoids; Food-Drug Interactions; HEK293 Cells; Hepatocytes; Heptanoic Acids; Humans; Inhibitory Concentration 50; Kaempferols; Liver-Specific Organic Anion Transporter 1; Metformin; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transporter 1; Pyrroles; Quercetin; Rutin; Solute Carrier Organic Anion Transporter Family Member 1B3; Sulfobromophthalein; Tritium

2012
Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: AMP-Activated Protein Kinases; Apigenin; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Cyclic AMP Response Element-Binding Protein; Enzyme Activators; Forkhead Box Protein O1; Forkhead Transcription Factors; Gluconeogenesis; Glucose; Glucose Transporter Type 4; Glucosides; Hep G2 Cells; Histone Deacetylases; Humans; Insulin Resistance; Metformin; Naphthalimides; Phosphorylation; Pyrones; Thiophenes; Transcription Factors

2015
Scutellarin Exerts Hypoglycemic and Renal Protective Effects in db/db Mice via the Nrf2/HO-1 Signaling Pathway.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Animals; Apigenin; Glucuronates; Heme Oxygenase-1; Hypoglycemic Agents; Kidney; Metformin; Mice; NF-E2-Related Factor 2; Signal Transduction

2019
Metformin-induced ROS upregulation as amplified by apigenin causes profound anticancer activity while sparing normal cells.
    Scientific reports, 2021, 07-07, Volume: 11, Issue:1

    Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Antineoplastic Agents; Apigenin; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Drug Synergism; Fibroblasts; Forkhead Box Protein O3; Humans; Metformin; Models, Biological; Reactive Oxygen Species; Signal Transduction

2021
Both
    Biomolecules, 2020, 01-05, Volume: 10, Issue:1

    Topics: Animals; Antioxidants; Chamomile; Female; Hypothyroidism; Matricaria; Metformin; Oxidative Stress; Plant Extracts; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Thyroid Gland; Thyroid Hormones

2020