metformin has been researched along with androstenedione in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (18.18) | 18.2507 |
| 2000's | 20 (60.61) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Açbay, O; Gündoğdu, S | 1 |
| Bergiele, A; Diamanti-Kandarakis, E; Kouli, C; Tsianateli, T | 1 |
| Koivunen, RM; Martikainen, HK; Morin-Papunen, LC; Ruokonen, A | 1 |
| Bayram, F; Keleştimur, F; Sahin, Y; Unlühizarci, K | 1 |
| Cianci, A; De Leo, V; Ditto, A; la Marca, A; Morgante, G | 1 |
| Bayram, F; Keleştimur, F; Sahin, Y; Tutuş, A; Unlühizarci, K | 1 |
| Awadalla, SG; Cameron, D; Fontaine, RN; Glueck, CJ; Phillips, H; Wang, P | 1 |
| Evans, WS; Kauma, SW; Nestler, JE; Ratts, VS; Stovall, DW; Vandermolen, DT | 1 |
| Attia, GR; Carr, BR; Rainey, WE | 1 |
| Koivunen, RM; Martikainen, HK; Morin-Papunen, LC; Ruokonen, A; Tapanainen, JS | 1 |
| Huang, Z; Li, J; Shen, H; Song, J; Zhang, Y | 1 |
| Durmusoglu, F; Elter, K; Imir, G | 1 |
| De Pergola, G; Lorusso, F; Loverro, G; Mei, L; Nicolardi, V; Selvaggi, L | 1 |
| Gambineri, A; Heiman, ML; Pagotto, U; Pasquali, R; Tschöp, M; Vicennati, V | 1 |
| Cianci, A; De Leo, V; la Marca, A; Morgante, G; Palumbo, M; Petraglia, F | 1 |
| Brincat, M; Galea, R; Hole, D; Mansfield, R; Mason, H | 1 |
| Bellows, AB; Eagleson, CA; Gingrich, MB; Hu, K; Marshall, JC | 1 |
| Battaglia, C; Gamba, O; Genazzani, AD; Malavasi, B; Strucchi, C; Tortolani, F | 1 |
| Fleming, R; Harborne, L; Ling, D; MacLaughlin, DT; Norman, J; Sattar, N; Seifer, DB | 1 |
| Choktanasiri, W; Rojanasakul, A; Sophonsritsuk, A; Tingthanatikul, Y; Wansumrith, S; Weerakiet, S | 1 |
| Koivunen, R; Morin-Papunen, L; Perheentupa, A; Piltonen, T; Ruokonen, A; Tapanainen, JS | 1 |
| Fleming, R; Harborne, LR; Norman, JE; Sattar, N | 1 |
| Liu, Y; Lv, L; Sun, Y; Tan, K | 1 |
| Arslan, M; Ayvaz, G; Cakir, N; Karakoç, A; Tiras, B; Törüner, FB; Yilmaz, M | 1 |
| Adya, R; Chen, J; Farhatullah, S; Heutling, D; Kaur, J; Lehnert, H; Lewandowski, KC; O'Hare, JP; Randeva, HS; Tan, BK | 1 |
| De Cicco, S; Guido, M; Lanzone, A; Proto, C; Romualdi, D; Tagliaferri, V | 1 |
| Atkin, SL; Coady, AM; Kilpatrick, ES; Sathyapalan, T; Smith, KA | 1 |
| Belfiore, A; D'Orrico, B; Fava, A; Fruci, B; Guzzi, P; Malaguarnera, R; Mazza, A; Veltri, P | 1 |
| Baracat, EC; Carbonel, AA; do Amaral, VC; Fuchs, LF; Macedo, LA; Maria Soares, J; Simões, MJ; Simões, RS; Simoncini, T | 1 |
| Aksoy, AN; Dokuyucu, R; Gozukara, IO; Kucur, SK; Kurt, RK; Ozcan, O; Ozgur, T; Pınar, N | 1 |
| Carlsen, SM; Salvesen, Ø; Shetelig Løvvik, T; Stridsklev, S; Vanky, E | 1 |
| He, B; Li, C; Xing, C | 1 |
1 review(s) available for metformin and androstenedione
| Article | Year |
|---|---|
Insulin Sensitizers for Improving the Endocrine and Metabolic Profile in Overweight Women With PCOS.
Topics: Adult; Androstenedione; Blood Glucose; Female; Glucagon-Like Peptide-1 Receptor; Hormones; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Menstruation; Metabolome; Metformin; Network Meta-Analysis; Overweight; Polycystic Ovary Syndrome; Randomized Controlled Trials as Topic; Sex Hormone-Binding Globulin; Testosterone; Thiazolidinediones | 2020 |
17 trial(s) available for metformin and androstenedione
| Article | Year |
|---|---|
Therapeutic effects of metformin on insulin resistance and hyperandrogenism in polycystic ovary syndrome.
Topics: Adult; Androstenedione; Blood Glucose; Female; Glucose Clamp Technique; Humans; Hyperandrogenism; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Obesity; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone | 1998 |
Metformin therapy improves the menstrual pattern with minimal endocrine and metabolic effects in women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Blood Glucose; Cohort Studies; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Humans; Hypoglycemic Agents; Insulin; Luteinizing Hormone; Menstruation; Metformin; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Sex Hormone-Binding Globulin; Testosterone; Time Factors | 1998 |
Effects of metformin on gonadotropin-induced ovulation in women with polycystic ovary syndrome.
Topics: Adult; Androstenedione; Clomiphene; Drug Therapy, Combination; Estradiol; Female; Fertility Agents, Female; Follicle Stimulating Hormone; Humans; Hypoglycemic Agents; Luteinizing Hormone; Metformin; Ovulation; Polycystic Ovary Syndrome; Pregnancy; Prospective Studies; Treatment Outcome | 1999 |
Metformin increases the ovulatory rate and pregnancy rate from clomiphene citrate in patients with polycystic ovary syndrome who are resistant to clomiphene citrate alone.
Topics: Adolescent; Adult; Androstenedione; Body Mass Index; Clomiphene; Dehydroepiandrosterone Sulfate; Double-Blind Method; Drug Resistance; Female; Follicle Stimulating Hormone; Humans; Infertility, Female; Luteinizing Hormone; Metformin; Ovulation Induction; Placebos; Polycystic Ovary Syndrome; Pregnancy; Testosterone | 2001 |
Clinical, endocrine and metabolic effects of metformin added to ethinyl estradiol-cyproterone acetate in non-obese women with polycystic ovarian syndrome: a randomized controlled study.
Topics: Adolescent; Adult; Androstenedione; Body Constitution; Body Mass Index; Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Sex Hormone-Binding Globulin | 2002 |
Clinical and endocrinological effects of 6 months of metformin treatment in young hyperinsulinemic patients affected by polycystic ovary syndrome.
Topics: Adolescent; Adult; Androstenedione; Apolipoprotein A-I; Apolipoproteins B; Body Constitution; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Glucose Tolerance Test; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Insulin; Longitudinal Studies; Menstrual Cycle; Metformin; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone; Treatment Outcome; Triglycerides | 2002 |
Plasma ghrelin, obesity, and the polycystic ovary syndrome: correlation with insulin resistance and androgen levels.
Topics: Adult; Androgens; Androstenedione; Diet, Reducing; Female; Ghrelin; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Peptide Hormones; Polycystic Ovary Syndrome | 2002 |
Obese patients with polycystic ovary syndrome: evidence that metformin does not restore sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by ovarian steroids.
Topics: Adult; Androstenedione; Estrone; Feedback, Physiological; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Hypoglycemic Agents; Luteinizing Hormone; Metformin; Obesity; Polycystic Ovary Syndrome; Pulsatile Flow; Testosterone | 2003 |
Metformin administration modulates and restores luteinizing hormone spontaneous episodic secretion and ovarian function in nonobese patients with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Area Under Curve; Blood Glucose; C-Peptide; Estradiol; Female; Follicle Stimulating Hormone; Humans; Insulin; Luteinizing Hormone; Menstrual Cycle; Metformin; Obesity; Ovary; Polycystic Ovary Syndrome; Testosterone | 2004 |
Metformin reduces serum mullerian-inhibiting substance levels in women with polycystic ovary syndrome after protracted treatment.
Topics: Adult; Androstenedione; Anti-Mullerian Hormone; Female; Glycoproteins; Humans; Hypoglycemic Agents; Metformin; Ovary; Polycystic Ovary Syndrome; Prospective Studies; Testicular Hormones | 2005 |
Metformin and weight loss in obese women with polycystic ovary syndrome: comparison of doses.
Topics: Administration, Oral; Androstenedione; Blood Glucose; Dehydroepiandrosterone Sulfate; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Luteinizing Hormone; Metformin; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Weight Loss | 2005 |
Effects of metformin combined with cyproterone acetate on clinical features, endocrine and metabolism of non-obese women with polycystic ovarian syndrome.
Topics: Adolescent; Adult; Androgen Antagonists; Androstenedione; Body Mass Index; Cyproterone Acetate; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome | 2005 |
The effects of rosiglitazone and metformin on menstrual cyclicity and hirsutism in polycystic ovary syndrome.
Topics: Adult; Androstenedione; Female; Glucose Tolerance Test; Hirsutism; Humans; Hypoglycemic Agents; Insulin; Menstrual Cycle; Metformin; Polycystic Ovary Syndrome; Rosiglitazone; Testosterone; Thiazolidinediones; Treatment Outcome | 2005 |
Insulin and metformin regulate circulating and adipose tissue chemerin.
Topics: Adipose Tissue; Adolescent; Adult; Androstenedione; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estradiol; Female; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Omentum; Organ Culture Techniques; Polycystic Ovary Syndrome; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone; Up-Regulation; Young Adult | 2009 |
Atorvastatin therapy decreases androstenedione and dehydroepiandrosterone sulphate concentrations in patients with polycystic ovary syndrome: randomized controlled study.
Topics: Adrenal Glands; Adult; Androstenedione; Atorvastatin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Double-Blind Method; Female; Heptanoic Acids; Humans; Hyperandrogenism; Insulin; Metformin; Ovary; Placebos; Polycystic Ovary Syndrome; Pyrroles; Testosterone; Treatment Outcome; United Kingdom | 2012 |
In PCOS patients the addition of low-dose spironolactone induces a more marked reduction of clinical and biochemical hyperandrogenism than metformin alone.
Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Female; Hirsutism; Humans; Hyperandrogenism; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Spironolactone; Testosterone; Young Adult | 2014 |
Cervical Length and Androgens in Pregnant Women With Polycystic Ovary Syndrome: Has Metformin Any Effect?
Topics: Adolescent; Adult; Androgens; Androstenedione; Cervical Length Measurement; Dehydroepiandrosterone Sulfate; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Young Adult | 2016 |
15 other study(ies) available for metformin and androstenedione
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Can metformin reduce insulin resistance in polycystic ovary syndrome?
Topics: Adult; Androstenedione; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Fasting; Female; Follicle Stimulating Hormone; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Luteinizing Hormone; Metformin; Placebos; Polycystic Ovary Syndrome; Testosterone; Triglycerides | 1996 |
The treatment of insulin resistance does not improve adrenal cytochrome P450c17alpha enzyme dysregulation in polycystic ovary syndrome.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenedione; Blood Glucose; Cytochrome P-450 Enzyme System; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Isoenzymes; Metformin; Polycystic Ovary Syndrome | 1999 |
The effects of metformin on insulin resistance and ovarian steroidogenesis in women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Buserelin; Case-Control Studies; Female; Follicle Stimulating Hormone; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Luteinizing Hormone; Metformin; Polycystic Ovary Syndrome; Statistics, Nonparametric | 1999 |
Polycystic ovary syndrome, infertility, familial thrombophilia, familial hypofibrinolysis, recurrent loss of in vitro fertilized embryos, and miscarriage.
Topics: Abortion, Habitual; Adult; Amenorrhea; Androstenedione; Embryo Transfer; Female; Fertilization in Vitro; Fibrinolysis; Humans; Hypoglycemic Agents; Infertility, Female; Metformin; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Polymorphism, Genetic; Pregnancy; Testosterone; Thrombophilia; Treatment Outcome | 2000 |
Metformin directly inhibits androgen production in human thecal cells.
Topics: 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Female; Gene Expression Regulation, Enzymologic; Humans; Metformin; Phosphoproteins; Progesterone; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Testosterone; Theca Cells; Transcription, Genetic | 2001 |
Ovarian steroidogenic response to human chorionic gonadotrophin in obese women with polycystic ovary syndrome: effect of metformin.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Blood Glucose; Chorionic Gonadotropin; Estradiol; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Obesity; Ovary; Polycystic Ovary Syndrome; Steroids; Testosterone | 2001 |
[Effects of metformin on the plasminogen activator system, endocrine, metabolic profiles in patients with polycystic ovary syndrome and clomiphene resistant cases].
Topics: Adult; Androstenedione; Blood Glucose; Cholesterol; Cholesterol, LDL; Clomiphene; Drug Resistance; Estradiol; Female; Fertility Agents, Female; Follicle Stimulating Hormone; Hormones; Humans; Hypoglycemic Agents; Insulin; Luteinizing Hormone; Metformin; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Polycystic Ovary Syndrome; Pregnancy; Testosterone; Treatment Outcome | 2002 |
Insulin-lowering treatment reduces aromatase activity in response to follicle-stimulating hormone in women with polycystic ovary syndrome.
Topics: Adult; Androstenedione; Aromatase; Aromatase Inhibitors; Estradiol; Female; Follicle Stimulating Hormone; Humans; Insulin Antagonists; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Testosterone | 2002 |
Metformin has direct effects on human ovarian steroidogenesis.
Topics: Adult; Androstenedione; Estradiol; Female; Granulosa Cells; Humans; Hypoglycemic Agents; Metformin; Middle Aged; Ovarian Follicle; Progesterone; Theca Cells | 2003 |
Efficacy of metformin on ovulation induction in Asian women with polycystic ovary syndrome.
Topics: Adult; Androstenedione; Body Mass Index; Clomiphene; Coitus; Female; Humans; Hypoglycemic Agents; Infertility, Female; Insemination, Artificial; Insulin; Metformin; Ovarian Follicle; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Progesterone; Ultrasonography; Waist-Hip Ratio | 2004 |
Serum anti-Müllerian hormone levels remain high until late reproductive age and decrease during metformin therapy in women with polycystic ovary syndrome.
Topics: Adult; Aging; Androstenedione; Anti-Mullerian Hormone; Case-Control Studies; Estradiol; Female; Follicle Stimulating Hormone; Glycoproteins; Humans; Hypoglycemic Agents; Inhibins; Luteinizing Hormone; Metformin; Ovarian Follicle; Polycystic Ovary Syndrome; Testicular Hormones; Testosterone | 2005 |
The metabolic status modulates the effect of metformin on the antimullerian hormone-androgens-insulin interplay in obese women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androgens; Androstenedione; Anti-Mullerian Hormone; Body Mass Index; Female; Follicular Phase; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Metformin; Obesity; Polycystic Ovary Syndrome; Testosterone; Waist-Hip Ratio; Young Adult | 2011 |
Effects of metformin on the adrenal cortex of androgenized rats.
Topics: Adrenal Cortex; Androstenedione; Animals; Female; Hypoglycemic Agents; Metformin; Organ Size; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Testosterone Propionate | 2015 |
Effect of colchicine on polycystic ovary syndrome: an experimental study.
Topics: Androstenedione; Animals; C-Reactive Protein; Colchicine; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Female; Humans; Metformin; Ovarian Follicle; Ovary; Polycystic Ovary Syndrome; Random Allocation; Rats; Rats, Wistar; Testosterone; Tubulin Modulators | 2016 |