metformin has been researched along with adenine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Becker, ML; Hofman, A; Stricker, BH; Uitterlinden, AG; van Schaik, RH; Visser, LE | 1 |
| Alivanis, P; Aperis, G; Arvanitis, A; Paliouras, C; Zervos, A | 1 |
| Kazazis, C | 1 |
| Hidaka, K; Iseki, K; Kobayashi, M; Komazawa, H; Ogura, J; Yamaguchi, H | 1 |
| Cao, L; Gao, L; Jiang, T; Shi, JQ; Tan, L; Tan, MS; Wang, HF; Yu, JT; Zhang, QQ; Zhang, YD; Zhu, XC | 1 |
| Cai, N; Chen, D; Feng, Y; Pan, Z; Tang, Q; Tian, N; Wang, C; Wang, Q; Wang, X; Wu, Y; Xia, D; Xu, D; Xu, H; Yan, M; Zhang, JJ; Zhang, X; Zhou, K; Zhou, Y | 1 |
| Hayakawa, N; Hishiki, T; Kubo, A; Minamishima, S; Minamishima, YA; Morisaki, H; Nakamura, T; Oyaizu-Toramaru, T; Suematsu, M; Suhara, T; Yamaguchi, K | 1 |
| Brand, K; D'Haese, PC; De Broe, ME; De Maré, A; Gottwald-Hostalek, U; Kamel, S; Lalau, JD; Neven, E; Opdebeeck, B; Verhulst, A; Vervaet, B | 1 |
| Komori, H; Morokado, F; Nakanishi, T; Nishizawa, K; Tamai, I; Yoda, N | 1 |
| Adham, SA; Al Suleimani, Y; Al Za'abi, M; Ali, BH; Ali, H; Ashique, M; Manoj, P; Nemmar, A | 1 |
| Corremans, R; D'Haese, PC; De Broe, ME; Leysen, H; Maudsley, S; Neven, E; Verhulst, A; Vervaet, BA | 1 |
14 other study(ies) available for metformin and adenine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study.
Topics: Adenine; Aged; Aged, 80 and over; Bile; Blood Glucose; Cohort Studies; Creatinine; Diabetes Mellitus; Drug Resistance, Multiple; Epithelial Cells; Female; Genetic Variation; Genotype; Glomerular Filtration Rate; Glycated Hemoglobin; Guanine; Hepatocytes; Humans; Kidney; Male; Metformin; Organic Cation Transport Proteins; Polymorphism, Single Nucleotide; White People | 2009 |
Lactic acidosis after concomitant treatment with metformin and tenofovir in a patient with HIV infection.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adenine; Aged; Anti-HIV Agents; Diabetes Mellitus, Type 2; Drug Interactions; HIV Infections; Humans; Hypoglycemic Agents; Male; Metformin; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir | 2011 |
A case of lactic acidosis (LA) after administration of tenofovir and metformin in a diabetic patient with recently diagnosed HIV infection.
Topics: Acidosis, Lactic; Adenine; Anti-HIV Agents; Diabetes Mellitus, Type 2; HIV Infections; Humans; Hypoglycemic Agents; Male; Metformin; Organophosphonates; Reverse Transcriptase Inhibitors | 2011 |
Renal uptake of substrates for organic anion transporters Oat1 and Oat3 and organic cation transporters Oct1 and Oct2 is altered in rats with adenine-induced chronic renal failure.
Topics: Adenine; Animals; Anti-Bacterial Agents; Body Weight; Gene Expression; Hypoglycemic Agents; Kidney; Kidney Failure, Chronic; Male; Metformin; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Penicillin G; Rats; Rats, Wistar; RNA, Messenger; Serum | 2013 |
Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy.
Topics: Adenine; AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Brain; Brain Ischemia; Disease Models, Animal; Hypoglycemic Agents; Male; Metformin; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2014 |
Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo.
Topics: Adenine; Adenylate Kinase; Animals; Apoptosis; Autophagy; Cellular Senescence; Enzyme Activation; Female; Gene Expression Regulation; Intervertebral Disc Degeneration; Male; Metformin; Neuroprotective Agents; Nucleus Pulposus; Oxidative Stress; Rats, Sprague-Dawley; RNA, Small Interfering; tert-Butylhydroperoxide | 2016 |
Targeting Oxygen-Sensing Prolyl Hydroxylase for Metformin-Associated Lactic Acidosis Treatment.
Topics: Acidosis, Lactic; Adenine; Animals; Disease Models, Animal; Enzyme Inhibitors; Gluconeogenesis; Kidney; Liver; Male; Metformin; Mice, Inbred C57BL; Oxygen; Procollagen-Proline Dioxygenase; Renal Insufficiency, Chronic; RNA, Messenger; Survival Analysis; Up-Regulation | 2017 |
Metformin prevents the development of severe chronic kidney disease and its associated mineral and bone disorder.
Topics: Adenine; Animals; Chronic Kidney Disease-Mineral and Bone Disorder; Disease Models, Animal; Humans; Hypoglycemic Agents; Male; Metformin; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Severity of Illness Index; Treatment Outcome; Vascular Calcification; Warfarin | 2018 |
Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.
Topics: Adenine; Animals; Antiporters; Cephalexin; Creatinine; Disease Models, Animal; Down-Regulation; Humans; Hyperuricemia; Kidney; Male; Metformin; Organic Cation Transport Proteins; Organic Cation Transporter 2; Oxonic Acid; Pharmacokinetics; Rats; Rats, Wistar; RNA, Messenger; Uric Acid | 2019 |
The Effect of Metformin in Diabetic and Non-Diabetic Rats with Experimentally-Induced Chronic Kidney Disease.
Topics: Adenine; Animals; Diabetes Mellitus, Experimental; Kidney; MAP Kinase Signaling System; Metformin; Rats; Rats, Wistar; Renal Insufficiency, Chronic | 2021 |
Progression of established non-diabetic chronic kidney disease is halted by metformin treatment in rats.
Topics: Adenine; Animals; Canagliflozin; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Male; Metformin; Proteomics; Rats; Renal Insufficiency, Chronic | 2022 |