metformin has been researched along with acarbose in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 11 (64.71) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Choi, JS; Jung, HA; Min, BS; Paudel, P; Seong, SH | 1 |
| Chen, M; Ding, W; Dodd, RH; Lu, K; Ma, Y; Song, X; Sun, H; Wang, D; Wang, K; Wang, R; Yu, P; Yuan, P; Zhang, Y | 1 |
| Ananthakrishnan, R; Jayamurthy, P; Krishnan, SL; Madhukrishnan, M; Manojkumar, TK; Neethu, S; Prabha, B; Radhakrishnan, KV; Rameshkumar, KB; Sherin, DR | 1 |
| Chen, M; Jiang, H; Jin, Z; Ma, Y; Sun, H; Wang, K; Yu, P; Zhang, M; Zhang, Y; Zheng, H | 1 |
| Chen, H; Lei, Y; Liu, W; Ma, B; Xu, H; Xu, L; Zhang, X; Zhu, C | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Washburn, WN | 1 |
| Bisht, SS; Fatima, S; Jaiswal, N; Rahuja, N; Srivastava, AK; Tamrakar, AK; Tripathi, RP | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, T; Chen, Z; Jiang, X; Li, X; Wang, M; Wu, J; Zhang, B; Zheng, D | 1 |
2 review(s) available for metformin and acarbose
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Development of the renal glucose reabsorption inhibitors: a new mechanism for the pharmacotherapy of diabetes mellitus type 2.
Topics: Animals; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Glucose; Glucosides; Humans; Hypoglycemic Agents; Kidney; Sodium-Glucose Transporter 2 Inhibitors | 2009 |
15 other study(ies) available for metformin and acarbose
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Structure-related protein tyrosine phosphatase 1B inhibition by naringenin derivatives.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavanones; Hep G2 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Protein Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 1 | 2017 |
Synthesis of 6-hydroxyaurone analogues and evaluation of their α-glucosidase inhibitory and glucose consumption-promoting activity: Development of highly active 5,6-disubstituted derivatives.
Topics: alpha-Glucosidases; Benzofurans; Glucose; Glycoside Hydrolase Inhibitors; Hep G2 Cells; Humans; Molecular Docking Simulation; Saccharomyces cerevisiae | 2017 |
Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair.
Topics: alpha-Glucosidases; Binding Sites; Cell Line; Cell Survival; Diabetes Mellitus, Type 2; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Molecular Dynamics Simulation; Muscle Cells; Myristicaceae; Phytochemicals; Plant Bark; Plant Extracts; Plant Stems; Protein Structure, Tertiary; Resorcinols | 2018 |
New insights into the biological activities of Chrysanthemum morifolium: Natural flavonoids alleviate diabetes by targeting α-glucosidase and the PTP-1B signaling pathway.
Topics: Animals; Cell Line, Tumor; Cholesterol; Chrysanthemum; Cricetulus; Diabetes Mellitus, Experimental; Flavonoids; Glucose; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Male; Mice; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Signal Transduction; Streptozocin; Triglycerides | 2019 |
Novel Hydroxychalcone-Based Dual Inhibitors of Aldose Reductase and α-Glucosidase as Potential Therapeutic Agents against Diabetes Mellitus and Its Complications.
Topics: Aldehyde Reductase; alpha-Glucosidases; Animals; Antioxidants; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glucose; Hypoglycemic Agents; Rats | 2022 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Synthetic studies in butenonyl C-glycosides: Preparation of polyfunctional alkanonyl glycosides and their enzyme inhibitory activity.
Topics: alpha-Glucosidases; Animals; Blood Glucose; Enzyme Inhibitors; Glucose-6-Phosphatase; Glycogen Phosphorylase; Glycoside Hydrolase Inhibitors; Glycosides; Rats | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Synthesis and anti-hyperglycemic activity of hesperidin derivatives.
Topics: Administration, Oral; alpha-Glucosidases; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Flavanones; Glycoside Hydrolase Inhibitors; Hep G2 Cells; Hesperidin; Humans; Hypoglycemic Agents; Mice; Structure-Activity Relationship | 2012 |