metformin and D-fructopyranose

metformin has been researched along with D-fructopyranose in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.89)	18.7374
1990's	4 (7.55)	18.2507
2000's	14 (26.42)	29.6817
2010's	21 (39.62)	24.3611
2020's	13 (24.53)	2.80

Authors

Authors	Studies
Bartosiewicz, W; Czyzyk, A; Lao, B; Orlowska, K; Szczepanik, Z	1
Bhanot, S; McNeill, JH; Verma, S	2
Hector, R; Hobensack, CK; Luo, J; Quan, J; Reaven, GM; Sullivan, C; Tsai, J	1
Faure, P; Favier, A; Halimi, S; Richard, MJ; Rossini, E; Wiernsperger, N	1
Ewart, HS; Severson, D; Shimoni, Y	1
Chang, CT; Chen, CC; Chen, RH; Sheen, LY; Shih, HC; Wang, HJ; Wang, TY	1
Anuradha, CV; Anurag, P	1
Sanders, TA; Taylor, D; Werneke, U	1
Baret, G; Dalmaz, Y; Géloën, A; Grassi-Kassisse, D; Peyronnet, J; Wiernsperger, N	1
Anuradha, CV; Srividhya, S	1
Anuradha, CV; Ravichandran, MK; Srividhya, S	1
Fitchet, M; Gorska, M; Hamann, A; Masson, E; Moore, R; Sun, X; Toplak, H; Vercruysse, F	1
Gadde, KM; Hollander, P; Leung, A; Rosenstock, J; Strauss, R; Sun, X	1
Barclay, D; Faure, P; Halimi, S; Joyeux-Faure, M	1
Al-Zaman, Y; Aylwin, S	1
Chang, T; Desai, K; Jia, X; Wang, X; Wu, L	1
Kapoor, S	1
Anuradha, CV; Kannappan, S	1
Ellinger, LK; Ipema, HJ; Stachnik, JM	1
Benhamou, PY; Cottet-Rousselle, C; Fontaine, E; Halimi, S; Lablanche, S; Lamarche, F; Leverve, X	1
Bray, GA; Ryan, DH	1
Chien, KY; Hsu, KF; Hsu, MC; Huang, CC; Kuo, CH	1
Borroni, JS; Boudou, S; Carranza, A; Donoso, AS; Peredo, HA; Puyó, AM; Santander, Y	1
Bergheim, I; Bischoff, SC; Kanuri, G; Spruss, A; Stahl, C	1
Bagul, PK; Banerjee, SK; Bastia, T; Chakravarty, S; Madhusudana, K; Matapally, S; Middela, H; Padiya, R; Reddy, BR	1
Andrés-Hernando, A; Cicerchi, C; Garcia, G; Hodges, RS; Hunter, B; Ishimoto, T; Johnson, RJ; Lanaspa, MA; Li, N; Mant, CT; Rivard, CJ; Roncal-Jimenez, CA; Sánchez-Lozada, LG; Thomas, J	1
Adeli, K; Ji, J; Jiang, B; Liu, L; Lu, J; Meng, H; Meng, QH; Randell, E; Wang, D	1
Huang, F; Kou, J; Li, J; Liu, B; Liu, K; Qi, L; Sun, Y; Wang, M; Xiao, N	1
Curtin, CR; Ford, L; Heald, D; Manitpisitkul, P; Shalayda, K; Wang, SS	1
Bagul, PK; Banerjee, SK; Chakravarty, S; Jhelum, P; Kaur, G; Kumar, A; Kumar, KP; Maitra, S; Reddy, BR	1
Antu, KA; Mishra, A; Nair, A; Raghu, KG; Riya, MP; Srivastava, AK	1
Andrade, C	1
Agius, L; Al-Oanzi, ZH; Alshawi, A; Arden, C; Fountana, S; Moonira, T; Patman, G; Petrie, JL; Reeves, HL; Tudhope, SJ	1
Aguirre, JI; Cortizo, AM; Felice, JI; McCarthy, AD; Schurman, L; Sedlinsky, C	1
Kosuru, R; Singh, S	1
Centurión, D; Gutiérrez-Lara, EJ; Navarrete-Vázquez, G; Sánchez-López, A	1
Al-Salami, H; Brook, E; Fimognari, N; Lam, V; Mamo, JC; Mooranian, A; Nesbit, M; Takechi, R	1
Abd El Latif, HA; AinShoka, AA; El Shazly, KA; Zayed, EA	1
Latiff, AA; Mardiana, AA; Sahema, ZCT; Santhana, RL; Syed Ahmad Fuad, SB; Zaidun, NH	1
Bagul, PK; Banerjee, SK; Rai, RC	1
Amadi, JA; Amadi, PU; Njoku, UC; Osuoha, JO	1
Arunsak, B; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Jaiwongkam, T; Jinawong, K; Pongkan, W; Pratchayasakul, W; Tokuda, M	1
Gryciuk, ME; Maciejczyk, M; Mil, KM; Pawlukianiec, C; Zalewska, A; Żendzian-Piotrowska, M; Ładny, JR	1
Arita, K; Ito, T; Kambe, Y; Kasamo, Y; Kawahara, KI; Kikuchi, K; Maruyama, I; Otsuka, S; Takada, S; Yamakuchi, M; Yoshimoto, K	1
Ahmed, HMS; Ibrahim, IAAE; Ibrahim, WS; Mahmoud, AAA; Mahmoud, MF	1
Chen, YY; Cheng, PW; Ho, CY; Sun, GC; Tseng, CJ; Wu, TT; Yeh, TC	1
Erukainure, OL; Ijomone, OK; Islam, MS; Msomi, NZ; Olofinsan, KA; Salau, VF	1
Chen, J; Cheng, J; Guan, F; Huang, X; Li, M; Li, Y; Lin, G; Liu, Y; Ma, X; Su, Z; Xie, J; Xu, L; Yu, Q	1
Adeolu, AI; Amobi, CA; Chikezie, CC; Egedigwe-Ekeleme, AC; Eleazu, CO; Eleazu, KC; Igwe, VM; Kalu, AO; Kalu, WO; Kanu, S; Njemanze, CC; Obeten, UN; Obi, V; Odii, BC; Ogunwa, SC; Okoh, PN; Okorie, UC; Onyia, CJ; Onyia, S; Ossai, P; Ozor, G; Ugada, OJ	1
Brown, JD; Donahoo, WT; Hampp, C; Sarayani, A; Winterstein, AG	1
Chen, LM; Cheng, Y; Deng, XQ; Fang, T; Guo, H; Li, T; Qu, JR; Sun, B; Xu, CF	1
Anand, A; Batra, GK; Bhansali, S; Patil, AN; Sharma, S	1

Reviews

5 review(s) available for metformin and D-fructopyranose

Article	Year
Options for pharmacological management of obesity in patients treated with atypical antipsychotics. International clinical psychopharmacology, 2002, Volume: 17, Issue:4 Topics: Amantadine; Antipsychotic Agents; Cimetidine; Cyclobutanes; Fluoxetine; Fructose; Humans; Lactones; Metformin; Nizatidine; Obesity; Orlistat; Topiramate; Weight Gain	2002
Emerging concepts in the medical and surgical treatment of obesity. Frontiers of hormone research, 2008, Volume: 36 Topics: Adipose Tissue; Amyloid; Anticonvulsants; Antidepressive Agents; Anxiety; Appetite Regulation; Bariatric Surgery; Body Mass Index; Bupropion; Cholecystokinin; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Cyclobutanes; Depression; Diabetes Mellitus, Type 2; Female; Fluoxetine; Fructose; Ghrelin; Humans; Intra-Abdominal Fat; Islet Amyloid Polypeptide; Isoxazoles; Lactones; Leptin; Metabolic Syndrome; Metformin; Obesity; Obesity, Morbid; Orlistat; Oxyntomodulin; Peptide YY; Piperidines; Polycystic Ovary Syndrome; Pyrazoles; Rimonabant; Sertraline; Sleep Apnea, Obstructive; Surgical Procedures, Operative; Topiramate; Zonisamide	2008
Efficacy of metformin and topiramate in prevention and treatment of second-generation antipsychotic-induced weight gain. The Annals of pharmacotherapy, 2010, Volume: 44, Issue:4 Topics: Anti-Obesity Agents; Antipsychotic Agents; Fructose; Humans; Hypoglycemic Agents; Metformin; Obesity; Psychotic Disorders; Randomized Controlled Trials as Topic; Topiramate; Weight Gain	2010
Cardiometabolic Risks in Schizophrenia and Directions for Intervention, 3: Psychopharmacological Interventions. The Journal of clinical psychiatry, 2016, Volume: 77, Issue:9 Topics: Anti-Obesity Agents; Antipsychotic Agents; Aripiprazole; Cardiovascular Diseases; Fructose; Humans; Hypoglycemic Agents; Metabolic Syndrome; Metformin; Schizophrenia; Topiramate	2016
Pleiotropic Properties of Valsartan: Do They Result from the Antiglycooxidant Activity? Literature Review and Oxidative medicine and cellular longevity, 2021, Volume: 2021 Topics: Acetylcysteine; Animals; Antioxidants; Captopril; Chloramines; Chromans; Fructose; Glucose; Glycosylation; Humans; Metformin; Oxidation-Reduction; Pyruvaldehyde; Serum Albumin, Bovine; Thioctic Acid; Tosyl Compounds; Valsartan	2021

Trials

3 trial(s) available for metformin and D-fructopyranose

Article	Year
Efficacy and safety of topiramate in combination with metformin in the treatment of obese subjects with type 2 diabetes: a randomized, double-blind, placebo-controlled study. International journal of obesity (2005), 2007, Volume: 31, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Obesity Agents; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Fructose; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Topiramate; Treatment Outcome; Weight Loss	2007
A randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of topiramate controlled release in the treatment of obese type 2 diabetic patients. Diabetes care, 2007, Volume: 30, Issue:6 Topics: Adult; Aged; Anti-Obesity Agents; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diet, Reducing; Double-Blind Method; Exercise; Female; Fructose; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Placebos; Safety; Topiramate	2007
Pharmacokinetic interactions between topiramate and pioglitazone and metformin. Epilepsy research, 2014, Volume: 108, Issue:9 Topics: Adolescent; Adult; Analysis of Variance; Anticonvulsants; Area Under Curve; Dose-Response Relationship, Drug; Drug Interactions; Female; Fructose; Humans; Hypoglycemic Agents; Male; Metformin; Pioglitazone; Tandem Mass Spectrometry; Thiazolidinediones; Time Factors; Topiramate; Young Adult	2014

Other Studies

45 other study(ies) available for metformin and D-fructopyranose

Article	Year
The effect of short-term administration of antidiabetic biguanide derivatives on the blood lactate levels in healthy subjects. Diabetologia, 1978, Volume: 14, Issue:2 Topics: Adolescent; Adult; Biguanides; Blood Glucose; Buformin; Ethanol; Female; Fructose; Humans; Lactates; Male; Metformin; Middle Aged; Phenformin; Physical Exertion	1978
Antihypertensive effects of metformin in fructose-fed hyperinsulinemic, hypertensive rats. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3 Topics: Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Fructose; Hypertension; Insulin; Male; Metformin; Rats; Rats, Sprague-Dawley	1994
Decreased vascular reactivity in metformin-treated fructose-hypertensive rats. Metabolism: clinical and experimental, 1996, Volume: 45, Issue:9 Topics: Animals; Antihypertensive Agents; Fructose; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Male; Mesenteric Arteries; Metformin; Rats; Rats, Sprague-Dawley	1996
Nongenetic mouse models of non-insulin-dependent diabetes mellitus. Metabolism: clinical and experimental, 1998, Volume: 47, Issue:6 Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Sucrose; Disease Models, Animal; Fructose; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Tolbutamide	1998
An insulin sensitizer improves the free radical defense system potential and insulin sensitivity in high fructose-fed rats. Diabetes, 1999, Volume: 48, Issue:2 Topics: Animals; Dietary Carbohydrates; Free Radical Scavengers; Fructose; Hypoglycemic Agents; Insulin; Lipid Peroxides; Male; Metformin; Oxidoreductases; Rats; Rats, Wistar	1999
Insulin resistance and the modulation of rat cardiac K(+) currents. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:2 Topics: Animals; Cells, Cultured; Cycloheximide; Dietary Carbohydrates; Fructose; Heart; Heart Ventricles; Hyperinsulinism; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Resistance; Membrane Potentials; Metformin; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Vanadium Compounds	2000
Comparison of the metabolic effects of metformin and troglitazone on fructose-induced insulin resistance in male Sprague-Dawley rats. Journal of the Formosan Medical Association = Taiwan yi zhi, 2001, Volume: 100, Issue:3 Topics: Animals; Chromans; Fatty Acids, Nonesterified; Fructose; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Metformin; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone	2001
Metformin improves lipid metabolism and attenuates lipid peroxidation in high fructose-fed rats. Diabetes, obesity & metabolism, 2002, Volume: 4, Issue:1 Topics: Animals; Blood Glucose; Cholesterol; Dietary Carbohydrates; Fatty Acids, Nonesterified; Fructose; Hypoglycemic Agents; Insulin; Kidney; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Metformin; Rats; Rats, Wistar; Triglycerides	2002
Increased intraabdominal adipose tissue mass in fructose fed rats: correction by metformin. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2002, Volume: 110, Issue:6 Topics: Adipose Tissue; Animals; Diet; Fructose; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System	2002
Metformin improves liver antioxidant potential in rats fed a high-fructose diet. Asia Pacific journal of clinical nutrition, 2002, Volume: 11, Issue:4 Topics: Animals; Antioxidants; Dietary Carbohydrates; Fructose; Hypoglycemic Agents; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Metformin; Random Allocation; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances	2002
Metformin attenuates blood lipid peroxidation and potentiates antioxidant defense in high fructose-fed rats. Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB), 2002, Volume: 6, Issue:6 Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Dietary Sucrose; Fructose; Insulin; Insulin Resistance; Lipid Peroxidation; Metformin; Rats; Rats, Wistar	2002
Comparison of the effects of zinc alone and zinc associated with selenium and vitamin E on insulin sensitivity and oxidative stress in high-fructose-fed rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2007, Volume: 21, Issue:2 Topics: Animals; Antioxidants; Diet; Dietary Carbohydrates; Fructose; Glucose Clamp Technique; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Metformin; Micronutrients; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Wistar; Selenium; Vitamin E; Zinc	2007
Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats. Journal of hypertension, 2008, Volume: 26, Issue:4 Topics: Animals; Aorta; Dietary Carbohydrates; Fructose; Glutathione; Glycation End Products, Advanced; Hydrogen Peroxide; Hypertension; Hypoglycemic Agents; Lysine; Male; Mesenteric Arteries; Metformin; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Sprague-Dawley	2008
Strategies to control antipsychotic-induced weight gain. Psychoneuroendocrinology, 2008, Volume: 33, Issue:8 Topics: Anti-Obesity Agents; Antipsychotic Agents; Awareness; Body Weight; Bupropion; Clinical Competence; Fructose; Humans; Hypoglycemic Agents; Melatonin; Metformin; Obesity; Topiramate; Treatment Outcome; Weight Gain	2008
Insulin sensitizing actions of fenugreek seed polyphenols, quercetin & metformin in a rat model. The Indian journal of medical research, 2009, Volume: 129, Issue:4 Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Flavonoids; Fructose; Glucose Tolerance Test; Insulin; Insulin Resistance; Liver; Male; Metformin; Phenols; Plant Extracts; Polyphenols; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quercetin; Rats; Rats, Wistar; Seeds; Triglycerides; Trigonella	2009
Protection of pancreatic INS-1 β-cells from glucose- and fructose-induced cell death by inhibiting mitochondrial permeability transition with cyclosporin A or metformin. Cell death & disease, 2011, Mar-24, Volume: 2 Topics: Animals; Apoptosis; Biological Transport; Calcium; Cell Death; Cell Line; Cell Survival; Cyclosporine; Fructose; Glucose; Insulin-Secreting Cells; Metformin; Mitochondria; Permeability; Protective Agents; Rats	2011
Drug treatment of obesity. The Psychiatric clinics of North America, 2011, Volume: 34, Issue:4 Topics: Adolescent; Adult; Anti-Obesity Agents; Antidepressive Agents, Second-Generation; Body Weight; Bupropion; Child; Drug Approval; Drug Combinations; Energy Intake; Exenatide; Female; Fructose; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Lactones; Male; Metformin; Naltrexone; Narcotic Antagonists; Obesity; Orlistat; Patient Compliance; Peptides; Randomized Controlled Trials as Topic; Sympathomimetics; Topiramate; United States; United States Food and Drug Administration; Venoms	2011
Swim training reduces metformin levels in fructose-induced insulin resistant rats. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2012, Volume: 15, Issue:1 Topics: Animals; Fructose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Rats; Rats, Wistar; Swimming	2012
Metformin reduces vascular production of vasoconstrictor prostanoids in fructose overloaded rats. Autonomic & autacoid pharmacology, 2012, Volume: 32, Issue:1 Pt 2 Topics: Animals; Aorta, Thoracic; Fructose; Male; Mesenteric Arteries; Metabolic Syndrome; Metformin; Oxidation-Reduction; Prostaglandins; Rats; Rats, Sprague-Dawley; Vasoconstriction	2012
Metformin protects against the development of fructose-induced steatosis in mice: role of the intestinal barrier function. Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:7 Topics: Animals; Disease Models, Animal; Endotoxins; Fatty Liver; Fructose; Gene Expression; Hypoglycemic Agents; Insulin Resistance; Liver; Matrix Metalloproteinase 13; Matrix Metalloproteinase 9; Metformin; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Plasminogen Activator Inhibitor 1; RNA, Messenger; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Toll-Like Receptor 4; Triglycerides; Tumor Necrosis Factor-alpha	2012
Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. Pharmacological research, 2012, Volume: 66, Issue:3 Topics: Animals; Ascorbic Acid; Blood Glucose; Body Weight; Catalase; Eating; Fructose; Glucose Tolerance Test; Glutathione; Insulin; Insulin Resistance; Liver; Male; Metabolic Syndrome; Metformin; NF-E2-Related Factor 2; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Triglycerides; Uric Acid	2012
Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver. PloS one, 2012, Volume: 7, Issue:11 Topics: Adenylate Kinase; AMP Deaminase; Animals; Carbon-Carbon Double Bond Isomerases; Enzyme Activation; Fats; Fatty Liver; Fructose; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Isoenzymes; Male; Metformin; Oxidation-Reduction; Rats; Uric Acid	2012
The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. Cardiovascular diabetology, 2013, Apr-05, Volume: 12 Topics: Animals; Blood Glucose; Carotid Arteries; Carotid Artery Injuries; Carotid Stenosis; Cells, Cultured; Cholesterol; Fatty Acids, Nonesterified; Fructose; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Protective Agents; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Triglycerides; Vascular Access Devices; Wound Healing	2013
Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1. Pharmacological research, 2014, Volume: 89 Topics: Adipokines; Adipose Tissue; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Aorta; Culture Media, Conditioned; Diet; Fructose; Metformin; NF-kappa B; Palmitic Acid; Rats; Resveratrol; Ribonucleotides; Sirtuin 1; Sodium Salicylate; Stilbenes; Vasodilation	2014
Sirtuin 1 and 7 mediate resveratrol-induced recovery from hyper-anxiety in high-fructose-fed prediabetic rats. Journal of biosciences, 2016, Volume: 41, Issue:3 Topics: Animals; Antioxidants; Anxiety Disorders; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Epigenesis, Genetic; Fructose; Gene Expression Regulation; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Prediabetic State; Rats; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes	2016
Symplocos cochinchinensis enhances insulin sensitivity via the down regulation of lipogenesis and insulin resistance in high energy diet rat model. Journal of ethnopharmacology, 2016, Dec-04, Volume: 193 Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Dose-Response Relationship, Drug; Down-Regulation; Dyslipidemias; Ethanol; Fructose; Gene Expression Regulation, Enzymologic; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipogenesis; Liver; Magnoliopsida; Male; Metformin; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Solvents; Time Factors	2016
Opposite effects of a glucokinase activator and metformin on glucose-regulated gene expression in hepatocytes. Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:8 Topics: Active Transport, Cell Nucleus; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cells, Cultured; Diet, Western; Enzyme Activators; Fructose; Fructosediphosphates; Gene Expression Regulation, Enzymologic; Glucokinase; Glucose-6-Phosphatase; Glucose-6-Phosphate; Hepatocytes; Hypoglycemic Agents; Male; Metformin; Mice, Inbred C3H; Overweight; Promoter Regions, Genetic; Pyruvate Kinase; Rats, Wistar; Thiazoles	2017
Effects of fructose-induced metabolic syndrome on rat skeletal cells and tissue, and their responses to metformin treatment. Diabetes research and clinical practice, 2017, Volume: 126 Topics: Adipocytes; Animals; Bone and Bones; Bone Density; Cell Differentiation; Cells, Cultured; Fructose; Male; Mesenchymal Stem Cells; Metabolic Syndrome; Metformin; Osteogenesis; Rats; Rats, Wistar	2017
Pterostilbene ameliorates insulin sensitivity, glycemic control and oxidative stress in fructose-fed diabetic rats. Life sciences, 2017, Aug-01, Volume: 182 Topics: Animals; beta-Cyclodextrins; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fructose; Insulin Resistance; Male; Metabolic Syndrome; Metformin; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2017
Pharmacological evaluation of metformin and N-benzylbiguanide, a novel analogue of metformin, on the vasopressor responses to adrenergic system stimulation in pithed rats with fructose-induced insulin resistance. European journal of pharmacology, 2017, Nov-05, Volume: 814 Topics: Adrenergic Agonists; Animals; Biguanides; Blood Glucose; Blood Pressure; Fructose; Heart Rate; Hemodynamics; Insulin; Insulin Resistance; Male; Metformin; Rats; Rats, Wistar; Receptors, Adrenergic; Sympathetic Nervous System	2017
Probucol prevents blood-brain barrier dysfunction and cognitive decline in mice maintained on pro-diabetic diet. Diabetes & vascular disease research, 2019, Volume: 16, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Blood-Brain Barrier; Cerebral Cortex; Cognition; Cognition Disorders; Cytokines; Diabetes Mellitus, Experimental; Diet, High-Fat; Fructose; Glial Fibrillary Acidic Protein; Hippocampus; Hypoglycemic Agents; Inflammation Mediators; Insulin Resistance; Male; Maze Learning; Metformin; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Probucol	2019
Improvement of insulin resistance via increase of GLUT4 and PPARγ in metabolic syndrome-induced rats treated with omega-3 fatty acid or l-carnitine. Journal of biochemical and molecular toxicology, 2018, Volume: 32, Issue:11 Topics: Adiposity; Animals; Carnitine; Diet, Carbohydrate Loading; Diet, High-Fat; Dietary Supplements; Fatty Acids, Omega-3; Fructose; Glucose Transporter Type 4; Heart; Hypoglycemic Agents; Insulin Resistance; Intra-Abdominal Fat; Liver; Male; Metabolic Syndrome; Metformin; Myocardium; Organ Size; PPAR gamma; Random Allocation; Rats, Sprague-Dawley	2018
Effects of naringenin on vascular changes in prolonged hyperglycaemia in fructose-STZ diabetic rat model. Drug discoveries & therapeutics, 2019, Volume: 13, Issue:4 Topics: Animals; Diabetes Mellitus, Experimental; Drug Synergism; Flavanones; Fructose; Hyperglycemia; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Metformin; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin	2019
NLRP3 inflammasome drives inflammation in high fructose fed diabetic rat liver: Effect of resveratrol and metformin. Life sciences, 2020, Jul-15, Volume: 253 Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fructose; Hypoglycemic Agents; Inflammasomes; Inflammation; Insulin Resistance; Liver; Male; Metformin; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Resveratrol	2020
Potentiation of incretin hormones and modulation of metabolic enzymes as possible mechanisms behind the insulin sensitizing effects of cabbage-metformin treatment. Translational research : the journal of laboratory and clinical medicine, 2021, Volume: 230 Topics: Animal Feed; Animals; Brassica; Diet; Dietary Carbohydrates; Fructose; Hypoglycemic Agents; Incretins; Insulin Resistance; Male; Metformin; Rats; Rats, Wistar	2021
Not only metformin, but also D-allulose, alleviates metabolic disturbance and cognitive decline in prediabetic rats. Nutritional neuroscience, 2022, Volume: 25, Issue:6 Topics: Animals; Cognitive Dysfunction; Diet, High-Fat; Drinking Water; Fructose; Insulin Resistance; Insulins; Metformin; Obesity; Prediabetic State; Rats; Rats, Wistar	2022
1,5-Anhydro-D-fructose Protects against Rotenone-Induced Neuronal Damage In Vitro through Mitochondrial Biogenesis. International journal of molecular sciences, 2021, Sep-14, Volume: 22, Issue:18 Topics: Adenylate Kinase; Animals; Cell Death; Fructose; Gene Silencing; Metformin; Mitochondria; Neurons; Neuroprotective Agents; Organelle Biogenesis; PC12 Cells; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Rats; Rotenone	2021
Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance β-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin. Life sciences, 2021, Dec-01, Volume: 286 Topics: Animals; beta-Arrestin 2; Blood Glucose; Diet, High-Fat; Fructose; Glucose; Heart; Insulin; Insulin Resistance; Isoproterenol; Male; Metformin; Mice; Propranolol; Signal Transduction; Ventricular Remodeling	2021
Blocking of SGLT2 to Eliminate NADPH-Induced Oxidative Stress in Lenses of Animals with Fructose-Induced Diabetes Mellitus. International journal of molecular sciences, 2022, Jun-27, Volume: 23, Issue:13 Topics: Animals; Cataract; Diabetes Mellitus; Fructose; Metformin; NADP; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Resveratrol; Sodium-Glucose Transporter 2	2022
Ferulic acid mitigates diabetic cardiomyopathy via modulation of metabolic abnormalities in cardiac tissues of diabetic rats. Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:1 Topics: Acetylcholinesterase; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Fructose; Metformin; Oxidative Stress; Rats	2023
Metformin alleviates long-term high-fructose diet-induced skeletal muscle insulin resistance in rats by regulating purine nucleotide cycle. European journal of pharmacology, 2022, Oct-15, Volume: 933 Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylosuccinate Synthase; AMP-Activated Protein Kinases; Animals; Antioxidants; Diet; Fructose; Insulin; Insulin Resistance; Metabolic Syndrome; Metformin; Muscle, Skeletal; NF-E2-Related Factor 2; Purine Nucleotides; Rats	2022
Tert-butylhydroquinone abrogates fructose-induced insulin resistance in rats via mitigation of oxidant stress, NFkB-mediated inflammation in the liver but not the skeletal muscle of high fructose drinking rats. Journal of food biochemistry, 2022, Volume: 46, Issue:12 Topics: Animals; Fructose; Inflammation; Insulin Resistance; Liver; Male; Metabolic Syndrome; Metformin; Muscle, Skeletal; Oxidants; Rats	2022
Topiramate Utilization After Phentermine/Topiramate Approval for Obesity Management: Risk Minimization in the Era of Drug Repurposing. Drug safety, 2022, Volume: 45, Issue:12 Topics: Anti-Obesity Agents; Atorvastatin; Drug Approval; Drug Repositioning; Female; Fructose; Humans; Male; Metformin; Obesity; Phentermine; Pregnancy; Topiramate	2022
ChREBP-β/TXNIP aggravates frucose-induced renal injury through triggering ferroptosis of renal tubular epithelial cells. Free radical biology & medicine, 2023, Volume: 199 Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carrier Proteins; Epithelial Cells; Ferroptosis; Fructose; Glucose; Kidney Tubules; Metformin; Mice; Proteomics; Thioredoxins	2023
Scopoletin Improves Glucose Homeostasis in the High-Fructose High-Fat Diet-Induced Diabetes Model in Wistar Rats. Journal of medicinal food, 2023, Volume: 26, Issue:4 Topics: Animals; Blood Glucose; Diabetes Mellitus; Diet, High-Fat; Fructose; Glucose; Homeostasis; Hypoglycemic Agents; Insulin Resistance; Metformin; Rats; Rats, Wistar; Scopoletin	2023