metformin has been researched along with 4-phenylbutyric acid in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Huang, H; Kang, R; Luo, G; Wang, J; Yang, W; Zhao, Z | 1 |
| Ballester, MI; Berthier, A; García-Cabrero, AM; Heredia, M; Payá, M; Sánchez, MP; Sanz, P; Serratosa, JM | 1 |
| Sánchez, MP; Sánchez-Elexpuru, G; Sanz, P; Serratosa, JM | 1 |
1 review(s) available for metformin and 4-phenylbutyric acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 other study(ies) available for metformin and 4-phenylbutyric acid
| Article | Year |
|---|---|
Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Autophagy; Autophagy-Related Protein-1 Homolog; Cell Line, Tumor; Endoplasmic Reticulum Stress; Enzyme Activation; Gene Knockdown Techniques; Hepacivirus; Hepatitis C; Humans; Intracellular Signaling Peptides and Proteins; Mechanistic Target of Rapamycin Complex 1; Metformin; Models, Biological; Multiprotein Complexes; Phenylbutyrates; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Ribonucleotides; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins; Virus Replication | 2013 |
Pharmacological Interventions to Ameliorate Neuropathological Symptoms in a Mouse Model of Lafora Disease.
Topics: Animals; Brain; Disease Models, Animal; Fluorescent Antibody Technique; Gliosis; Glucans; Hippocampus; Inclusion Bodies; Lafora Disease; Metformin; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neuropsychological Tests; Phenylbutyrates; Protein Aggregates; Trehalose; Ubiquitin-Protein Ligases; Ubiquitinated Proteins | 2016 |
4-Phenylbutyric acid and metformin decrease sensitivity to pentylenetetrazol-induced seizures in a malin knockout model of Lafora disease.
Topics: Animals; Anticonvulsants; Brain; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Lafora Disease; Metformin; Mice; Mice, Inbred C57BL; Mice, Knockout; Pentylenetetrazole; Phenylbutyrates; Ubiquitin-Protein Ligases | 2017 |