Page last updated: 2024-08-23

metergoline and prazosin

metergoline has been researched along with prazosin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19906 (35.29)18.7374
1990's3 (17.65)18.2507
2000's3 (17.65)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Akunne, HC; Belliotti, TR; Brink, WA; Corbin, AE; Georgic, LM; Heffner, TG; Pugsley, TA; Shih, YH; Whetzel, SZ; Wise, LD; Wustrow, DJ; Zoski, KT1
Andricopulo, AD; Moda, TL; Montanari, CA1
Ang, KK; Arkin, MR; Chen, S; Doyle, PS; Engel, JC; McKerrow, JH1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Martin, I; Rinjard, P; Teste, JF1
Ramage, AG1
Barrett, JE; Hoffmann, SM; Nader, MA1
Baran, H; Hornykiewicz, O; Hörtnagl, H; Sapetschnig, G; Sperk, G1
Russell, RD; Stripling, JS1
Buczko, W; De Gaetano, G; Gambino, MC1
Benington, JH; Heller, HC1
Connoley, IP; Heal, DJ; Liu, YL; Stock, MJ1
Centurión, D; Gupta, S; MaassenVanDenBrink, A; Mehotra, S; Sánchez-López, A; Villalón, CM1
Adan, RA; Janhunen, SK; la Fleur, SE; van der Zwaal, EM1
Ishola, IO; Olayemi, SO; Umeh, EA; Yemitan, OK1

Other Studies

17 other study(ies) available for metergoline and prazosin

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: discovery of a potential atypical antipsychotic agent.
    Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; CHO Cells; Corpus Striatum; Cricetinae; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Hippocampus; Magnetic Resonance Spectroscopy; Oxazines; Rats; Receptors, Dopamine D4

1999
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Animals; Cattle; Cell Line; Cell Line, Tumor; Chagas Disease; Drug Evaluation, Preclinical; Hepatocytes; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted; Muscle, Skeletal; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma cruzi

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
Electrotherapy in mice: dopaminergic and noradrenergic effects in the Tail Suspension Test.
    Fundamental & clinical pharmacology, 1990, Volume: 4, Issue:1

    Topics: Animals; Antidepressive Agents; Dopamine Antagonists; Electric Stimulation Therapy; Immobilization; Male; Metergoline; Methysergide; Mice; Motor Activity; Norepinephrine; Prazosin

1990
Are drugs that act both on serotonin receptors and alpha 1-adrenoceptors more potent hypotensive agents than those that act only on alpha 1-adrenoceptors?
    Journal of cardiovascular pharmacology, 1988, Volume: 11 Suppl 1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Cats; Cinanserin; Ergolines; Ketanserin; Male; Metergoline; Piperidines; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes

1988
Behavioral effects of (+-) 3,4-methylenedioxyamphetamine (MDA) and (+-) 3,4-methylenedioxymethamphetamine (MDMA) in the pigeon: interactions with noradrenergic and serotonergic systems.
    Psychopharmacology, 1989, Volume: 98, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Ketanserin; Male; Metergoline; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Prazosin; Reinforcement Schedule; Serotonin; Sympathetic Nervous System

1989
Alpha 2-adrenoceptors modulate kainic acid-induced limbic seizures.
    European journal of pharmacology, 1985, Jul-17, Volume: 113, Issue:2

    Topics: Animals; Brain Chemistry; Clonidine; Diazepam; Haloperidol; Kainic Acid; Male; Metergoline; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seizures

1985
Monoaminergic and local anesthetic components of cocaine's effects on kindled seizure expression.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:3

    Topics: Amphetamine; Anesthetics, Local; Animals; Biogenic Amines; Cocaine; Drug Interactions; Haloperidol; Kindling, Neurologic; Lidocaine; Male; Metergoline; Prazosin; Propranolol; Rats; Seizures; Yohimbine

1985
Prolongation of rat tail bleeding time by ketanserin: mechanisms of action.
    European journal of pharmacology, 1984, Aug-17, Volume: 103, Issue:3-4

    Topics: Animals; Bleeding Time; Blood Coagulation; Blood Platelets; Blood Pressure; Drug Interactions; Fenclonine; Ketanserin; Male; Metergoline; Piperidines; Platelet Aggregation; Prazosin; Rats; Serotonin; Serotonin Antagonists; Sympatholytics; Tail

1984
Monoaminergic and cholinergic modulation of REM-sleep timing in rats.
    Brain research, 1995, May-29, Volume: 681, Issue:1-2

    Topics: Animals; Biogenic Monoamines; Cholinergic Antagonists; Electroencephalography; Male; Metergoline; Parasympathetic Nervous System; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Ritanserin; Serotonin Antagonists; Sleep, REM; Sympatholytics

1995
Pharmacological characterisation of the thermogenic effect of bupropion.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bupropion; Butaclamol; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Female; Isoquinolines; Metergoline; Naphthyridines; Oxygen Consumption; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Dopamine D1; Serotonin Antagonists; Thermogenesis; Time Factors

2004
Potential vascular alpha1-adrenoceptor blocking properties of an array of 5-HT receptor ligands in the rat.
    European journal of pharmacology, 2006, Mar-27, Volume: 535, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Buspirone; Clozapine; Decerebrate State; Dose-Response Relationship, Drug; Drug Interactions; Ergotamine; Heart Rate; Ketanserin; Lisuride; Male; Metergoline; Methiothepin; Methysergide; Phenylephrine; Piperazines; Pizotyline; Prazosin; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Serotonin Receptor Agonists; Yohimbine

2006
Inverse agonism at α2A adrenoceptors augments the hypophagic effect of sibutramine in rats.
    Obesity (Silver Spring, Md.), 2011, Volume: 19, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Cyclobutanes; Energy Intake; Feeding Behavior; Hyperphagia; Locomotion; Male; Metergoline; Norepinephrine; Obesity; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Satiety Response; Serotonin Receptor Agonists

2011
Antidepressant and anxiolytic effects of the methanol root extract of Capparis thonningii: involvement of monoaminergic, cholinergic and GABAergic systems.
    Drug research, 2015, Volume: 65, Issue:4

    Topics: Adrenergic Antagonists; Animals; Anti-Anxiety Agents; Antidepressive Agents; Atropine; Behavior, Animal; Biogenic Monoamines; Capparis; Cholinergic Agents; Cholinergic Neurons; Cyproheptadine; Dopamine Antagonists; Female; Flumazenil; GABA Agents; gamma-Aminobutyric Acid; Immobility Response, Tonic; Male; Metergoline; Methanol; Mice; Muscarinic Antagonists; Plant Extracts; Plant Roots; Prazosin; Serotonin Antagonists; Sulpiride; Yohimbine

2015