Page last updated: 2024-08-23

metergoline and fenfluramine

metergoline has been researched along with fenfluramine in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-199048 (73.85)18.7374
1990's16 (24.62)18.2507
2000's0 (0.00)29.6817
2010's1 (1.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Quock, RM; Weick, BG1
Clineschmidt, BV; McGuffin, JC; Pflueger, AB; Totaro, JA1
Di Renzo, G; Quattrone, A; Schettini, G; Scopacasa, F; Tedeschi, G1
Clineschmidt, BV; McGuffin, JC1
Quock, RM1
Clineschmidt, BV; Hanson, HM; McGuffin, JC; Pflueger, AB1
Hall, WG; Rosenblatt, JS; Williams, CL1
Bendotti, C; Borsini, F; Ferraris, A; Garattini, S; Mennini, T; Samanin, R1
Cocchi, D; Gil-Ad, I; Locatelli, V; Mantegazza, P; Müller, EE; Panerai, AE; Secchi, C1
Di Renzo, GF; Preziosi, P; Quattrone, A; Schettini, G1
Beal, GA; Quock, RM1
Baran, L; Maj, J; Palider, W1
Grignaschi, G; Samanin, R1
Campling, GM; Cowen, PJ; Ellis, PM; Gartside, SE; Ware, CJ1
Bizzi, A; Garattini, S; Grignaschi, G; Neill, JC; Padura, IM; Samanin, R1
Bendotti, C; Neill, JC; Samanin, R1
Cooper, SJ; Neill, JC1
Barone, D; Bendotti, C; Caccia, S; Garattini, S; Mennini, T; Samanin, R1
Gibbs, J; Nicolaïdis, S; Stallone, D1
Goodall, E; Silverstone, T3
Berendsen, HH; Broekkamp, CL; Oosterloo, SK; van Delft, AM1
Betti, R; Casanueva, FF; Cella, SG; Müller, EE1
Wielosz, M1
Liebelt, HJ; Menadue, MF; Willoughby, JO1
Berettera, C; Garattini, S; Invernizzi, R; Samanin, R1
Foresta, C; Mioni, R; Scandellari, C1
Rothwell, NJ; Stock, MJ1
Bendotti, C; Borsini, F; Samanin, R1
Garattini, S; Samanin, R; Thurlby, PL1
Cervo, L; Rochat, C; Samanin, R1
Invernizzi, R; Kmieciak-Kolada, K; Samanin, R1
Aleotti, A; Bendotti, C; Borsini, F; Garattini, S; Samanin, R1
Costa, E; Harsing, LG; Yang, HY1
Di Renzo, G; Preziosi, P; Quattrone, A; Schettini, G1
Curzon, G1
Burton, MJ; Fletcher, PJ1
Garattini, S; Samanin, R1
Miranda, GF; Roncucci, R; Verry, M1
Aguglia, U; Annunziato, L; Direnzo, GF; Quattrone, A; Scopacasa, F; Tedeschi, G1
Fornal, C; Radulovacki, M1
Borsini, F; Rech, RH; Samanin, R1
Cervo, L; Rochat, C; Romandini, S; Samanin, R1
Lazarova, M; Samanin, R1
Broekkamp, CL; Garrigou, D; LLoyd, KG1
Bunting, PR; Clineschmidt, BV1
Huot, S; Palfreyman, MG1
Bendotti, C; Borsini, F; Ferraris, A; Mennini, T; Samanin, R2
Fuller, RW; Stamm, NB; Yen, TT1
Blundell, JE; Latham, CJ1
Fletcher, PJ; Higgins, GA; Joharchi, N; Sellers, EM; Wang, Y1
Fletcher, PJ2
Bonanno, G; Raiteri, M; Vallebuona, F1
Grignaschi, G; Samanin, R; Sironi, F1
Nicolaidis, S; Orosco, M; Rouah-Rosilio, M1
Rowland, NE1
Anelli, M; Caccia, S; Fracasso, C; Grignaschi, G; Mantelli, B; Samanin, R1
Higgins, GA; Sellers, EM; Wang, Y1
Clifton, PG; Dourish, CT; Vickers, SP1
Costall, B; Neill, JC; Wilson, AW1
Bowersox, SS; Gao, D; Pettus, M; Wang, YX1
Boisvert, JP; Boschuetz, TJ; Choi, S; Mueller, CR; Resch, JM1

Reviews

2 review(s) available for metergoline and fenfluramine

ArticleYear
Serotoninergic mechanisms in human feeding: the pharmacological evidence.
    Appetite, 1986, Volume: 7 Suppl

    Topics: Amitriptyline; Antipsychotic Agents; Cyproheptadine; Diet; Feeding Behavior; Fenfluramine; Food Preferences; Humans; Hunger; Metergoline; Methysergide; Nervous System Physiological Phenomena; Obesity; Satiety Response; Serotonin; Synaptic Transmission; Tryptophan; Zimeldine

1986
Differential effects of pharmacological agents acting on monoaminergic systems on drug-induced anorexia.
    Progress in neuro-psychopharmacology, 1980, Volume: 4, Issue:4-5

    Topics: Amphetamine; Animals; Appetite Depressants; Dogs; Dopamine Antagonists; Fenfluramine; Hydroxydopamines; Metergoline; Methysergide; Mice; Norepinephrine; Raphe Nuclei; Rats; Serotonin Antagonists

1980

Trials

1 trial(s) available for metergoline and fenfluramine

ArticleYear
The interaction of metergoline, a 5-HT receptor blocker, and dexfenfluramine in human feeding.
    Clinical neuropharmacology, 1988, Volume: 11 Suppl 1

    Topics: Drug Interactions; Eating; Ergolines; Fenfluramine; Humans; Male; Metergoline; Taste

1988

Other Studies

62 other study(ies) available for metergoline and fenfluramine

ArticleYear
p-Chloroamphetamine-induced hyperthermia pharmacologically distinct from fenfluramine-induced hyperthermia.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:1

    Topics: Amphetamines; Animals; Body Temperature; Brain Stem; Cyproheptadine; Fenclonine; Fenfluramine; Fluoxetine; Haloperidol; Hydrazines; Lysergic Acid Diethylamide; Male; Metergoline; p-Chloroamphetamine; Rabbits; Serotonin; Time Factors

1979
Fenfluramine-induced enhancement of confinement motor activity: an indirect 5-hydroxytryptamine-like action?
    Neuropharmacology, 1975, Volume: 14, Issue:4

    Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Animals; Brain Chemistry; Carbidopa; Catecholamines; Cinanserin; Female; Fenclonine; Fenfluramine; Metergoline; Methylphenidate; Motor Activity; Rats

1975
Increased plasma prolactin levels induced in rats by d-fenfluramine: relation to central serotonergic stimulation.
    European journal of pharmacology, 1978, May-15, Volume: 49, Issue:2

    Topics: Animals; Fenclonine; Fenfluramine; Male; Metergoline; Prolactin; Quipazine; Rats; Serotonin; Stimulation, Chemical

1978
Pharmacological differentiation of the central 5-hydroxytryptamine-like actions of MK-212 (6-chloro-2[1-piperazinyl]-pyrazine),p-methoxyamphetamine and fenfluramine in an in vivo model system.
    European journal of pharmacology, 1978, Aug-15, Volume: 50, Issue:4

    Topics: Amphetamines; Animals; Dextroamphetamine; Drug Interactions; Fenclonine; Fenfluramine; Fluoxetine; In Vitro Techniques; Male; Metergoline; Muscle Contraction; Piperazines; Pyrazines; Rats; Serotonin; Time Factors

1978
Methergoline: a selective anti-tryptamine action in the rabbit hyperthermia model.
    Proceedings of the Western Pharmacology Society, 1978, Volume: 21

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Body Temperature; Cinanserin; Cyproheptadine; Ergolines; Fenfluramine; Male; Metergoline; Rabbits; Tryptamines

1978
Anorexigenic and ancillary actions of MK-212 (6-chloro-2-(1-piperazinyl)-pyrazine; CPP).
    Psychopharmacology, 1977, Nov-24, Volume: 55, Issue:1

    Topics: Animals; Appetite Depressants; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Eating; Female; Fenfluramine; Male; Metergoline; Motor Activity; Piperazines; Pyrazines; Rats; Self Administration

1977
Inhibition of suckling in weaning-age rats: a possible serotonergic mechanism.
    Journal of comparative and physiological psychology, 1979, Volume: 93, Issue:3

    Topics: Animal Population Groups; Animals; Animals, Suckling; Cinanserin; Feeding Behavior; Fenfluramine; Metergoline; Methysergide; Quipazine; Rats; Serotonin; Sucking Behavior

1979
Chlorophenylpiperazine: a central serotonin agonist causing powerful anorexia in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 308, Issue:2

    Topics: Animals; Appetite Depressants; Brain; Catecholamines; Dextroamphetamine; Feeding Behavior; Female; Fenfluramine; Metergoline; Piperazines; Rats; Serotonin; Synaptosomes

1979
Drug-induced changes of brain serotoninergic tone and insulin-induced growth hormone release in the dog.
    Neuroendocrinology, 1978, Volume: 25, Issue:2

    Topics: Animals; Brain; Clemastine; Clomipramine; Cyproheptadine; Dogs; Female; Fenfluramine; Growth Hormone; Insulin; Male; Metergoline; Methysergide; Pimozide; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1978
Effect of quipazine and D-fenfluramine, two serotonin-like drugs, on TSH secretion in basal and cold stimulated conditions in the rat.
    Life sciences, 1978, Jun-05, Volume: 22, Issue:21

    Topics: Animals; Cold Temperature; Fenfluramine; Male; Metergoline; Quinolines; Quipazine; Rats; Serotonin; Thyrotropin

1978
Fenfluramine-induced hyperthermia and stimulation in the rabbit.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 13, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Cinanserin; Cyproheptadine; Dose-Response Relationship, Drug; Fenfluramine; Fever; Haloperidol; Male; Metergoline; Phenyl Ethers; Propylamines; Rabbits; Receptors, Adrenergic; Receptors, Drug; Serotonin

1976
The effects of serotonergic and antiserotonergic drugs on the flexor reflex of spinal rat: a proposed model to evaluate the action on the central serotonin receptor.
    Journal of neural transmission, 1976, Volume: 38, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anthracenes; Clonidine; Cyproheptadine; Decerebrate State; Fenfluramine; Hindlimb; Lysergic Acid Diethylamide; Male; Metergoline; Muscle Contraction; p-Chloroamphetamine; Piperidines; Rats; Reflex; Serotonin; Tryptophan

1976
Role of 5-HT receptors in the effect of d-fenfluramine on feeding patterns in the rat.
    European journal of pharmacology, 1992, Mar-03, Volume: 212, Issue:2-3

    Topics: Animals; Feeding Behavior; Fenfluramine; Male; Metergoline; Pindolol; Rats; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Stereoisomerism

1992
Does metergoline selectively attenuate 5-HT mediated prolactin release?
    Psychopharmacology, 1991, Volume: 105, Issue:1

    Topics: Adolescent; Adult; Animals; Brain Chemistry; Fenfluramine; Haloperidol; Humans; Male; Metergoline; Prolactin; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists

1991
Role of 5-HT receptors in the effect of d-fenfluramine on gastric emptying and feeding behaviour as examined in the runway test.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Animals; Behavior, Animal; Feeding Behavior; Fenfluramine; Gastric Emptying; Male; Metergoline; Piperidines; Proglumide; Rats; Receptors, Serotonin; Ritanserin; Serotonin Antagonists

1991
Studies on the role of 5-HT receptors in satiation and the effect of d-fenfluramine in the runway test.
    European journal of pharmacology, 1990, Nov-06, Volume: 190, Issue:1-2

    Topics: Amidines; Animals; Feeding Behavior; Fenfluramine; Male; Metergoline; Piperidines; Rats; Receptors, Serotonin; Ritanserin; Satiation; Serotonin Antagonists

1990
Evidence that d-fenfluramine anorexia is mediated by 5-HT1 receptors.
    Psychopharmacology, 1989, Volume: 97, Issue:2

    Topics: Amidines; Animals; Appetite Depressants; Fenfluramine; Male; Metergoline; Pindolol; Piperidines; Rats; Receptors, Serotonin; Ritanserin; Serotonin Antagonists

1989
Evidence that central 5-HT2 receptors do not play an important role in the anorectic activity of D-fenfluramine in the rat.
    Neuropharmacology, 1989, Volume: 28, Issue:5

    Topics: Animals; Appetite Depressants; Brain Chemistry; Eating; Fenfluramine; Histamine H2 Antagonists; Male; Metergoline; Norfenfluramine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Spiperone

1989
Cholecystokinin-induced anorexia depends on serotoninergic function.
    The American journal of physiology, 1989, Volume: 256, Issue:5 Pt 2

    Topics: Amidines; Animals; Anorexia; Cholecystokinin; Dose-Response Relationship, Drug; Eating; Feeding and Eating Disorders; Fenfluramine; Male; Metergoline; Rats; Serotonin

1989
Effect of metergoline, fenfluramine, and 8-OHDPAT on catalepsy induced by haloperidol or morphine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Catalepsy; Drug Interactions; Fenfluramine; Haloperidol; Male; Metergoline; Mice; Morphine; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes

1988
Activation of the cholinergic system and growth hormone release in the dog: functional interactions with other neurotransmitters.
    Acta endocrinologica, 1985, Volume: 108, Issue:1

    Topics: Animals; Behavior, Animal; Cimetidine; Clemastine; Diphenhydramine; Dogs; Domperidone; Female; Fenfluramine; Growth Hormone; Male; Metergoline; Naloxone; Phentolamine; Physostigmine; Pimozide; Pizotyline; Propranolol; Radioimmunoassay; Receptors, Cholinergic; Synaptic Transmission

1985
Increased sensitivity to serotonergic agonists after repeated electroconvulsive shock in rats.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:5

    Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; Brain; Chlorides; Cyproheptadine; Electroshock; Fenfluramine; Lithium; Lithium Chloride; Male; Metergoline; Motor Activity; Piperazines; Rats; Serotonin; Synaptic Transmission

1985
Differential effect of d-fenfluramine and metergoline on food intake in human subjects.
    Appetite, 1988, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Anorexia; Appetite; Eating; Ergolines; Fenfluramine; Humans; Male; Metergoline; Satiety Response; Serotonin Antagonists; Time Factors

1988
Activation of 5-HT 1 serotonin receptors in the medial basal hypothalamus stimulates prolactin secretion in the unanaesthetized rat.
    Neuroendocrinology, 1988, Volume: 47, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Fenfluramine; Hypothalamus, Middle; Ketanserin; Male; Metergoline; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin

1988
d- and l-isomers of fenfluramine differ markedly in their interaction with brain serotonin and catecholamines in the rat.
    European journal of pharmacology, 1986, Jan-14, Volume: 120, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carboxy-Lyases; Catecholamines; Female; Fenfluramine; Metergoline; Rats; Serotonin; Stereoisomerism

1986
Evidence for serotoninergic system involvement in opioid control of luteinizing hormone secretion in man.
    Clinical endocrinology, 1986, Volume: 25, Issue:5

    Topics: Adult; Ergolines; Fenfluramine; Humans; Luteinizing Hormone; Male; Metergoline; Naloxone; Prolactin; Serotonin

1986
Effect of diet and fenfluramine on thermogenesis in the rat: possible involvement of serotonergic mechanisms.
    International journal of obesity, 1987, Volume: 11, Issue:4

    Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Fenfluramine; Guanosine Diphosphate; Hexamethonium Compounds; Male; Metergoline; Oxygen Consumption; Protein Deficiency; Rats; Rats, Inbred Strains; Serotonin

1987
Salbutamol, d-amphetamine and d-fenfluramine reduce sucrose intake in freely fed rats by acting on different neurochemical mechanisms.
    International journal of obesity, 1985, Volume: 9, Issue:4

    Topics: Albuterol; Amidines; Animals; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Eating; Epinephrine; Female; Fenfluramine; Hypothalamus; Metergoline; Propranolol; Rats; Sucrose

1985
Effects of serotonin antagonists on the performance of a simple food acquisition task in rats treated with fenfluramine isomers.
    Pharmacological research communications, 1985, Volume: 17, Issue:12

    Topics: Amidines; Animals; Dose-Response Relationship, Drug; Feeding Behavior; Fenfluramine; Male; Metergoline; Rats; Serotonin Antagonists

1985
Changes of physical morphine dependence in rats chronically treated with drugs acting on brain 5-hydroxytryptamine.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:2

    Topics: Animals; Brain Chemistry; Fenfluramine; Humans; Male; Metergoline; Morphine Dependence; Rats; Serotonin

1980
Is receptor activation involved in the mechanism by which (+)-fenfluramine and (+)-norfenfluramine deplete 5-hydroxytryptamine in the rat brain?
    British journal of pharmacology, 1982, Volume: 75, Issue:3

    Topics: Animals; Brain; Drug Synergism; Female; Fenfluramine; Hydroxyindoleacetic Acid; In Vitro Techniques; Metergoline; Norfenfluramine; Rats; Receptors, Serotonin; Reserpine; Serotonin

1982
D-Fenfluramine and D-norfenfluramine reduce food intake by acting on different serotonin mechanisms in the rat brain.
    Pharmacological research communications, 1982, Volume: 14, Issue:7

    Topics: Amidines; Animals; Brain; Brain Chemistry; Clomipramine; Depression, Chemical; Feeding Behavior; Female; Fenclonine; Fenfluramine; Metergoline; Norfenfluramine; Rats; Reserpine; Serotonin; Serotonin Antagonists

1982
Accumulation of hypothalamic endorphins after repeated injections of anorectics which release serotonin.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:3

    Topics: Animals; Appetite Depressants; beta-Endorphin; Endorphins; Enkephalin, Methionine; Fenclonine; Fenfluramine; Hypothalamus; Male; Metergoline; Peptides; Pituitary Gland; Rats; Rats, Inbred Strains; Serotonin

1982
Serotonergic involvement in neuroendocrine function.
    Pharmacological research communications, 1980, Volume: 12, Issue:3

    Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Dopamine; Fenclonine; Fenfluramine; Male; Metergoline; Prolactin; Quipazine; Raphe Nuclei; Rats; Serotonin

1980
Some behavioural interactions between 5-hydroxytryptamine and dopamine.
    Advances in experimental medicine and biology, 1981, Volume: 133

    Topics: Animals; Behavior, Animal; Dextroamphetamine; Dopamine; Fenclonine; Fenfluramine; Metergoline; Motor Activity; p-Chloroamphetamine; Rats; Serotonin; Tryptophan

1981
Effects of manipulations of peripheral serotonin on feeding and drinking in the rat.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:6

    Topics: Animals; Avoidance Learning; Drinking; Feeding Behavior; Fenfluramine; Male; Metergoline; Methysergide; Rats; Serotonin; Taste; Time Factors

1984
d-Fenfluramine and salbutamol: two drugs causing anorexia through different neurochemical mechanisms.
    International journal of obesity, 1984, Volume: 8 Suppl 1

    Topics: Albuterol; Animals; Appetite; Appetite Depressants; Clomipramine; Dextroamphetamine; Eating; Feeding Behavior; Fenfluramine; Metergoline; Norfenfluramine; Rats; Serotonin; Serotonin Antagonists

1984
Two novel agents affecting eating through an action on monoaminergic systems.
    International journal of obesity, 1984, Volume: 8 Suppl 1

    Topics: Animals; Appetite Depressants; Dextroamphetamine; Drug Tolerance; Eating; Female; Fenfluramine; Lethal Dose 50; Metergoline; Methysergide; Penfluridol; Phentolamine; Piperazines; Piperidines; Propranolol; Pyridines; Rats; Rats, Inbred Strains; Serotonin

1984
Prolactin secretion in man: a useful tool to evaluate the activity of drugs on central 5-hydroxytryptaminergic neurones. Studies with fenfluramine.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:5

    Topics: Adult; Brain; Dose-Response Relationship, Drug; Female; Fenfluramine; Humans; Male; Metergoline; Prolactin; Receptors, Serotonin

1983
Sleep suppressant action of fenfluramine in rats. I. Relation to postsynaptic serotonergic stimulation.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Fenfluramine; Flupenthixol; Humans; Male; Metergoline; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Sleep; Stereotyped Behavior; Synapses; Wakefulness

1983
Effects of d-amphetamine and d-fenfluramine on performance of rats in a food maze.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:4

    Topics: Animals; Behavior, Animal; Conditioning, Psychological; Dextroamphetamine; Drug Interactions; Drug Synergism; Fenfluramine; Food; Male; Metergoline; Rats; Reinforcement, Psychology; Serotonin Antagonists

1984
Differences in the effects of d-fenfluramine and morphine on various responses of rats to painful stimuli.
    Psychopharmacology, 1982, Volume: 76, Issue:2

    Topics: Animals; Fenfluramine; Male; Metergoline; Morphine; Pain; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism

1982
Serotonin mediation of the protective effect of clonidine against pentylenetetrazol-induced seizures in rats.
    Life sciences, 1983, May-16, Volume: 32, Issue:20

    Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Fenfluramine; Male; Metergoline; Methysergide; Pentylenetetrazole; Rats; Seizures; Serotonin

1983
Serotonin-mimetic and antidepressant drugs on passive avoidance learning by olfactory bulbectomised rats.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:5

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Clonidine; Ergolines; Fenfluramine; Fluoxetine; Imipramine; Male; Metergoline; Mianserin; Olfactory Bulb; Quipazine; Rats; Serotonin; Serotonin Antagonists

1980
Effects of gamma-vinyl GABA on food intake of rats.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Dextroamphetamine; Feeding Behavior; Fenfluramine; Food Deprivation; Hydroxydopamines; Male; Metergoline; Motor Activity; Rats; Rats, Inbred Strains; Time Factors; Transaminases; Vigabatrin

1982
Hyper- and hyposensitivity of central serotonin receptors:[3H]serotonin binding and functional studies in the rat.
    Brain research, 1980, May-12, Volume: 189, Issue:2

    Topics: Animals; Brain; Eating; Female; Fenfluramine; Humans; Metergoline; Rats; Receptors, Serotonin; Serotonin; Stereotyped Behavior

1980
Lowering of blood pressure by direct- and indirect-acting serotonin agonists in spontaneously hypertensive rats.
    Clinical and experimental hypertension, 1981, Volume: 3, Issue:3

    Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Fenfluramine; Hypertension; Male; Metergoline; Piperazines; Quinolines; Quipazine; Rats; Time Factors

1981
Repeated treatment with d-fenfluramine or metergoline alters cortex binding of 3H-serotonin and serotenergic sensitivity in rats.
    European journal of pharmacology, 1980, Jan-25, Volume: 61, Issue:2

    Topics: Animals; Appetite Depressants; Binding Sites; Cerebral Cortex; Ergolines; Female; Fenfluramine; Metergoline; Piperazines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Time Factors

1980
Characterisation of adjustments to the structure of feeding behaviour following pharmacological treatment: effects of amphetamine and fenfluramine and the antagonism produced by pimozide and methergoline.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:5

    Topics: Amphetamine; Animals; Ergolines; Feeding Behavior; Fenfluramine; Male; Metergoline; Mice; Pimozide; Rats

1980
Further studies to examine the nature of dexfenfluramine-induced suppression of heroin self-administration.
    Psychopharmacology, 1995, Volume: 120, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Eating; Fenfluramine; Heroin; Male; Metergoline; Rats; Rats, Wistar; Ritanserin; Self Administration; Time Factors

1995
Effects of d-fenfluramine and metergoline on responding for conditioned reward and the response potentiating effect of nucleus accumbens d-amphetamine.
    Psychopharmacology, 1995, Volume: 118, Issue:2

    Topics: Animals; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Fenfluramine; Male; Metergoline; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Serotonin; Serotonin Antagonists; Sodium Chloride; Stereoisomerism; Time Factors

1995
In vitro and in vivo effects of d-fenfluramine: no apparent relation between 5-hydroxytryptamine release and hypophagia.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:2

    Topics: Animals; Eating; Fenfluramine; Fluoxetine; Hypothalamus; In Vitro Techniques; Male; Metergoline; Microdialysis; Rats; Rats, Sprague-Dawley; Serotonin; Synaptosomes

1995
The 5-HT1B receptor mediates the effect of d-fenfluramine on eating caused by intra-hypothalamic injection of neuropeptide Y.
    European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Drug Interactions; Eating; Ergolines; Fenfluramine; Hyperphagia; Hypothalamus; Injections, Intraperitoneal; Injections, Subcutaneous; Ketanserin; Male; Metergoline; Neuropeptide Y; Paraventricular Hypothalamic Nucleus; Pindolol; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Antagonists

1995
Serotoninergic modulation of sodium appetite in the rat.
    Physiology & behavior, 1994, Volume: 55, Issue:5

    Topics: Animals; Appetite; Brain; Dose-Response Relationship, Drug; Female; Fenfluramine; Metergoline; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin; Serotonin; Sodium, Dietary; Water-Electrolyte Balance

1994
Tolerance to the anorectic effect of dexfenfluramine in rats: role of serotonin, cholecystokinin, and neuropeptide Y.
    Physiology & behavior, 1994, Volume: 55, Issue:2

    Topics: Animals; Appetite Depressants; Brain; Brain Chemistry; Cholecystokinin; Drug Tolerance; Eating; Female; Fenfluramine; Food Deprivation; Male; Metergoline; Neuropeptide Y; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Weight Loss

1994
Reciprocal interaction of 5-hydroxytryptamine and cholecystokinin in the control of feeding patterns in rats.
    British journal of pharmacology, 1993, Volume: 109, Issue:2

    Topics: Animals; Benzodiazepinones; Brain; Cholecystokinin; Devazepide; Feeding Behavior; Fenfluramine; Male; Metergoline; Rats; Rats, Sprague-Dawley; Satiety Response; Serotonin

1993
Preliminary findings with the indirect 5-HT agonist dexfenfluramine on heroin discrimination and self-administration in rats.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:4

    Topics: Animals; Discrimination Learning; Discrimination, Psychological; Fenfluramine; Generalization, Stimulus; Heroin; Heroin Dependence; Male; Metergoline; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors

1993
Behavioural evidence that d-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype.
    Psychopharmacology, 1996, Volume: 125, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Appetite Depressants; Appetitive Behavior; Drug Interactions; Fenfluramine; Male; Metergoline; Piperazines; Pyridines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists

1996
Injection of 5-HT into the nucleus accumbens reduces the effects of d-amphetamine on responding for conditioned reward.
    Psychopharmacology, 1996, Volume: 126, Issue:1

    Topics: Amphetamine; Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Fenfluramine; Male; Metergoline; Nucleus Accumbens; Random Allocation; Rats; Rats, Sprague-Dawley; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

1996
An investigation into the effects of 5-HT agonists and receptor antagonists on ethanol self-administration in the rat.
    Alcohol (Fayetteville, N.Y.), 1998, Volume: 16, Issue:3

    Topics: Animals; Buspirone; Dose-Response Relationship, Drug; Ethanol; Female; Fenfluramine; Fluoxetine; Metergoline; Ondansetron; Piperazines; Rats; Rats, Sprague-Dawley; Ritanserin; Selective Serotonin Reuptake Inhibitors; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

1998
Antinociceptive properties of fenfluramine, a serotonin reuptake inhibitor, in a rat model of neuropathy.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Fenfluramine; Formaldehyde; Injections, Intraventricular; Injections, Spinal; Ligation; Male; Metergoline; Motor Activity; Naloxone; Narcotic Antagonists; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Spinal Nerves; Synaptic Transmission

1999
Serotonin mediated changes in corticotropin releasing factor mRNA expression and feeding behavior isolated to the hypothalamic paraventricular nuclei.
    Neuroscience letters, 2011, Jul-12, Volume: 498, Issue:3

    Topics: Animals; Appetite Regulation; Arcuate Nucleus of Hypothalamus; Corticotropin-Releasing Hormone; Drug Interactions; Feeding Behavior; Fenfluramine; Male; Metergoline; Microinjections; Neuropeptide Y; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin

2011