Page last updated: 2024-09-02

metaphit and phencyclidine

metaphit has been researched along with phencyclidine in 54 studies

Compound Research Comparison

Studies (metaphit)	Trials (metaphit)	Recent Studies (post-2010) (metaphit)	Studies (phencyclidine)	Trials (phencyclidine)	Recent Studies (post-2010) (phencyclidine)
68	0	4	28,294	387	7,796

Protein Interaction Comparison

Protein	Taxonomy	phencyclidine (IC50)
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	0.1299
Lysosomal Pro-X carboxypeptidase	Homo sapiens (human)	0.091
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	0.1299
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	0.1299
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	0.1299
Glutamate receptor ionotropic, NMDA 1	Homo sapiens (human)	0.5563
Glutamate receptor ionotropic, NMDA 2A	Homo sapiens (human)	0.205
Glutamate receptor ionotropic, NMDA 2B	Homo sapiens (human)	1.2589
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	0.1299
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	0.1299
Sigma non-opioid intracellular receptor 1	Rattus norvegicus (Norway rat)	0.53
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	0.1299

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (51.85)	18.7374
1990's	11 (20.37)	18.2507
2000's	14 (25.93)	29.6817
2010's	1 (1.85)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Agrawal, AK; Greco, NJ; Jacobson, AE; Jamieson, GA; Jones, GD; Rice, KC; Tandon, NN; Tenner, TE; White, JG	1
Benuck, M; Jacobson, AE; Reith, ME; Rice, KC; Zimanyi, I	1
Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH; Philip, A; Rahman, MA	1
Danysz, W	1
Bolger, GT; Rice, KC	1
Bluth, LS; Bowen, WD; Jacobson, AE; Rice, KC	1
Debler, EA; Jacobson, AE; Lajtha, A; Lipovac, MN; Reith, ME; Rice, KC; Zlokovic, BV	1
Furukawa, H; Harrer, SM; Hiramatsu, M; Jacobson, AE; Kameyama, T; Maeda, Y; Nabeshima, T; Noda, A; Rice, KC; Tohyama, K	1
Jacobson, AE; Lessor, RA; Rice, KC; Schweri, MM	2
Jacobson, AE; Lajtha, A; Reith, ME; Rice, KC; Zimányi, I	1
Chun, BM; George, R; Jacobson, AE; Pechnick, RN; Rice, KC; Thurkauf, A; Wu, AA	1
French, ED; Jacobson, AE; Rice, KC	1
Domino, EF; Gole, D; Koek, W	1
Jacobson, AE; Johnson, KM; Lessor, RA; Rice, KC; Snell, LD; Yi, SJ	1
Nabeshima, T	1
Reith, ME	1
Chase, TN; Contreras, PC; Jackson, AE; Kuo, S; O'Donohue, TL; Rice, KC; Tamminga, CA; Tanimoto, K	1
Jacobson, AE; Koek, W; Rice, KC; Woods, JH	1
Huguenin, PN; Jacobson, AE; Mattson, MV; Rice, KC; Thurkauf, A	1
Bolger, GT; Rafferty, MF; Rice, KC; Skolnick, P; Weissman, BA	1
Jacobson, AE; Mattson, M; Rafferty, MF; Rice, KC	1
Contreras, PC; Jacobson, AE; Lessor, RA; O'Donohue, TL; Rafferty, MF; Rice, KC	1
Domino, EF; Head, R; Holsztynska, EJ; Jacobson, AE; Koek, W; Lessor, RA; Rafferty, MF; Rice, KC; Woods, JH	1
Jacobson, AE; Koek, W; Lessor, RA; Rice, KC; Woods, JH	1
Blake, J; Church, J; Davies, SN; Jacobson, AE; Lessor, RA; Lodge, D; Rice, KC	1
Contreras, PC; Freedman, R; Hoffer, B; Jacobson, AE; Johnson, S; Lessor, RA; O'Donohue, TL; Olsen, K; Rafferty, MF; Rice, KC	1
Freedman, R; Hoffer, BJ; Jacobson, AE; Lessor, RA; Palmer, MR; Rice, KC; Wang, Y	1
Kim, MB; Palmer, MR; Wang, Y	1
Berger, P; Jacobson, AE; Reith, ME; Rice, KC; Sershen, H	1
Freedman, R; Hoffer, B; Jacobson, AE; Lessor, RA; Mattson, MV; Palmer, M; Rice, KC; Wang, Y	1
Hoffer, B; Jacobson, AE; Lessor, R; Pang, K; Rice, KC; Wang, Y	1
Berger, P; Jacobsen, AE; Lessor, RA; Reith, MA; Rice, KC	1
Albanese, R; Hogan, MV; Reith, M; Wieraszko, A	1
Markovic, O; Susić, V	1
Brum, JM; Estafanous, FG; Murray, PA; Schubert, A; Tsuchida, H	1
Stanojlovic, O; Susic, V; Zivanovic, D	4
Stanojlović, OP; Susić, VT; Zivanović, DP	1
Holland, T; Killian, C; Lajtha, A; Lipovac, MN; Poleksic, A	1
Mikhaleva, I; Mirković, S; Stanojlović, O; Zivanović, D	1
Mirkovic, S; Stanojlovic, O; Susic, V; Zivanovic, D	1
Cuevas, J; Zhang, H	1
Mikhaleva, II; Mirković, SD; Stanojlović, OP; Zivanović, DP	1
Hivanović, D; Stanojlović, O; Susić, V	1
Hrncić, D; Stanojlović, O; Susić, V; Zivanović, D	1
Cuevas, J; Guerrero, WR; Herrera, Y; Katnik, C; Pennypacker, KR	1
Hrncić, D; Rasić, A; Stanojlović, O; Susić, V; Zivanović, D	1
Hrncić, DR; Stanojlović, OP; Susić, VT; Zivanović, DP	1
Djuric, D; Hrncić, D; Loncar-Stevanović, H; Rasić, A; Stanojlović, O; Susić, V	1
Djurić, D; Hrncić, D; Mladenović, D; Radosavljević, T; Rasić, A; Stanojlović, O; Susić, V; Vucević, D	1
Behensky, A; Cuevas, J; Deng, W; Katnik, C	1

Reviews

1 review(s) available for metaphit and phencyclidine

Article	Year
[Recent topics of phencyclidine, the drug induces psychosis]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1987, Volume: 107, Issue:8 Topics: Amino Acids; Animals; Humans; Neuropeptides; Phencyclidine; Psychoses, Substance-Induced; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Substance-Related Disorders	1987

Other Studies

53 other study(ies) available for metaphit and phencyclidine

Article	Year
Phencyclidine binds to blood platelets with high affinity and specifically inhibits their activation by adrenaline. The Biochemical journal, 1992, Jul-01, Volume: 285 ( Pt 1) Topics: Binding, Competitive; Blood Platelets; Cells, Cultured; Chromatography, Gel; Cyclic AMP; Dioxolanes; Dizocilpine Maleate; Epinephrine; Humans; Phencyclidine; Piperidines; Platelet Activation; Receptors, Neurotransmitter; Receptors, Phencyclidine	1992
Effect of metaphit on dopaminergic neurotransmission in rat striatal slices: involvement of the dopamine transporter and voltage-dependent sodium channel. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Batrachotoxins; Calcium; Carbon Radioisotopes; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Guanidine; Guanidines; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Phencyclidine; Rats; Rats, Inbred Strains; Sodium Channels; Synaptic Transmission; Tetrodotoxin; Tritium; Veratridine	1991
Isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter. Molecular pharmacology, 1991, Volume: 39, Issue:3 Topics: Animals; Benzamides; Binding, Competitive; Brain Stem; Carrier Proteins; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Ligands; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Thiocyanates	1991
Metaphit fails to antagonize PCP-induced passive avoidance deficit. Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:1 Topics: Animals; Avoidance Learning; Dizocilpine Maleate; In Vitro Techniques; Kinetics; Male; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes	1991
Interactions between phencyclidine and nifedipine at 45Ca2(+)-uptake sites on mouse brain neurons. Biochemical pharmacology, 1990, Jun-01, Volume: 39, Issue:11 Topics: Animals; Brain; Calcium; Calcium Channels; Kinetics; Male; Mice; Neurons; Nifedipine; Phencyclidine; Potassium	1990
Acylation of sigma receptors by Metaphit, an isothiocyanate derivative of phencyclidine. European journal of pharmacology, 1989, Feb-28, Volume: 161, Issue:2-3 Topics: Acylation; Animals; Behavior, Animal; Brain Chemistry; Electrophysiology; Guinea Pigs; In Vitro Techniques; Membranes; Phencyclidine; Piperidines; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Phencyclidine	1989
Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice. European journal of pharmacology, 1989, Jun-08, Volume: 165, Issue:1 Topics: Acoustic Stimulation; Animals; Injections; Injections, Intravenous; Mice; Mice, Inbred BALB C; Orbit; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Time Factors	1989
Effects of metaphit on phencyclidine and serotonin2 receptors. Neuroscience letters, 1989, Jul-31, Volume: 102, Issue:2-3 Topics: Animals; Behavior, Animal; Ketanserin; Male; Phencyclidine; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; Receptors, Phencyclidine; Receptors, Serotonin; Time Factors	1989
Metaphit inhibits dopamine transport and binding of [3H]methylphenidate, a proposed marker for the dopamine transport complex. Life sciences, 1989, Volume: 45, Issue:18 Topics: Animals; Biological Transport; Biomarkers; Corpus Striatum; Dopamine; In Vitro Techniques; Kinetics; Male; Methylphenidate; Phencyclidine; Rats; Rats, Inbred Strains; Synaptosomes	1989
Long-term blockade of the dopamine uptake complex by metaphit, an isothiocyanate derivative of phencyclidine. Synapse (New York, N.Y.), 1989, Volume: 3, Issue:3 Topics: Animals; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Hydrogen-Ion Concentration; Injections, Intraventricular; Kinetics; Male; Mazindol; Membrane Proteins; Mice; Nerve Tissue Proteins; Phencyclidine; Radioligand Assay	1989
Metaphit antagonizes phencyclidine-induced hypothermia in the rat. Life sciences, 1989, Volume: 45, Issue:5 Topics: Animals; Body Temperature; Cerebral Ventricles; Hypothermia; Injections, Intraventricular; Injections, Subcutaneous; Male; Phencyclidine; Rats; Rats, Inbred Strains; Reference Values	1989
Metaphit, a proposed phencyclidine (PCP) antagonist, prevents PCP-induced locomotor behavior through mechanisms unrelated to specific blockade of PCP receptors. European journal of pharmacology, 1987, Aug-21, Volume: 140, Issue:3 Topics: Animals; Body Weight; Brain Chemistry; Dextroamphetamine; Dopamine; Injections; Injections, Intravenous; Injections, Intraventricular; Male; Motor Activity; Nucleus Accumbens; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine	1987
Metaphit, a proposed phencyclidine receptor acylator: disruption of mouse motor behavior and absence of PCP antagonist activity. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1 Topics: Animals; Cerebral Ventricles; Injections, Intraventricular; Isothiocyanates; Male; Mice; Mice, Inbred Strains; Motor Activity; Pentobarbital; Phencyclidine; Receptors, Neurotransmitter; Receptors, Phencyclidine; Thiocyanates	1987
Phencyclidine (PCP)-like inhibition of N-methyl-D-aspartate-evoked striatal acetylcholine release, H-TCP binding and synaptosomal dopamine uptake by metaphit, a proposed PCP receptor acylator. Life sciences, 1987, Dec-14, Volume: 41, Issue:24 Topics: Acetylcholine; Acylation; Animals; Aspartic Acid; Corpus Striatum; Dopamine; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine; Synaptosomes; Tritium; Tritolyl Phosphates	1987
Cocaine receptors on monoamine transporters and sodium channels. NIDA research monograph, 1988, Volume: 88 Topics: Animals; Biological Transport; Brain Chemistry; Cocaine; Dopamine; Drug Tolerance; Humans; Phencyclidine; Phosphatidylinositols; Receptors, Drug; Serotonin; Sodium Channels; Structure-Activity Relationship	1988
PCP-induced alterations in cerebral glucose utilization in rat brain: blockade by metaphit, a PCP-receptor-acylating agent. Synapse (New York, N.Y.), 1987, Volume: 1, Issue:5 Topics: Acylation; Animals; Autoradiography; Brain; Carbon Radioisotopes; Deoxy Sugars; Deoxyglucose; Kinetics; Male; Organ Specificity; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine	1987
Phencyclidine (PCP)-like discriminative stimulus effects of metaphit and of 2-amino-5-phosphonovalerate in pigeons: generality across different training doses of PCP. Psychopharmacology, 1987, Volume: 93, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Chlordiazepoxide; Columbidae; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Pentobarbital; Phencyclidine; Valine	1987
Etoxadrol-meta-isothiocyanate: a potent, enantioselective, electrophilic affinity ligand for the phencyclidine-binding site. FEBS letters, 1988, Oct-10, Volume: 238, Issue:2 Topics: Acylation; Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Dioxolanes; Phencyclidine; Piperidines; Rats; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, mu; Receptors, Phencyclidine; Stereoisomerism	1988
Acylating phencyclidines irreversibly enhance brain calcium antagonist binding. Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:1 Topics: Animals; Brain; Male; Membranes; Mice; Mice, Inbred ICR; Nifedipine; Nitrendipine; Phencyclidine; Stimulation, Chemical	1986
A specific acylating agent for the [3H]phencyclidine receptors in rat brain. FEBS letters, 1985, Feb-25, Volume: 181, Issue:2 Topics: Acylation; Animals; Brain; Corpus Striatum; Hippocampus; Male; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine; Structure-Activity Relationship	1985
A specific alkylating ligand for phencyclidine (PCP) receptors antagonizes PCP behavioral effects. European journal of pharmacology, 1985, May-20, Volume: 111, Issue:3 Topics: Alkylating Agents; Animals; Behavior, Animal; Humans; Male; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stereotyped Behavior	1985
Effects of metaphit, a proposed phencyclidine receptor acylator, on catalepsy in pigeons. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3 Topics: Acylation; Animals; Catalepsy; Columbidae; Humans; Ketamine; Phencyclidine; Proadifen; Receptors, Neurotransmitter; Receptors, Phencyclidine	1985
Metaphit, a proposed phencyclidine receptor acylator: phencyclidine-like behavioral effects and evidence of absence of antagonist activity in pigeons and in rhesus monkeys. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:2 Topics: Acylation; Animals; Ataxia; Catalepsy; Columbidae; Discrimination Learning; Drug Synergism; Ketamine; Macaca mulatta; Phenazocine; Phencyclidine; Receptors, Neurotransmitter; Receptors, Phencyclidine; Species Specificity; Stereotyped Behavior	1986
Is Metaphit a phencyclidine antagonist? Studies with ketamine, phencyclidine and N-methylaspartate. Life sciences, 1986, Jun-30, Volume: 38, Issue:26 Topics: Action Potentials; Animals; Aspartic Acid; Depression, Chemical; Drug Interactions; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Quisqualic Acid; Rats; Receptors, Opioid; Receptors, sigma; Spinal Cord	1986
Metaphit, an acylating ligand for phencyclidine receptors: characterization of in vivo actions in the rat. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3 Topics: Acylation; Amphetamine; Animals; Ataxia; Caudate Nucleus; Dose-Response Relationship, Drug; Injections, Intraventricular; Ligands; Male; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Stereotyped Behavior	1986
Electrophysiological interactions of isomers of cyclazocine with the phencyclidine antagonist metaphit in rat cerebellar Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1986, Volume: 6, Issue:11 Topics: Animals; Cyclazocine; Electrophysiology; Male; Naloxone; Neurons; Phencyclidine; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine	1986
Interactions of metaphit with phencyclidine and sigma agonist actions in rat cerebellum: determination of specificity and selectivity. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1 Topics: Animals; Cerebellum; Dioxolanes; Drug Interactions; Electrophysiology; Isomerism; Male; Phencyclidine; Piperidines; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Substrate Specificity	1987
Metaphit prevents locomotor activation induced by various psychostimulants and interferes with the dopaminergic system in mice. Neuropharmacology, 1988, Volume: 27, Issue:1 Topics: Amphetamine; Animals; Biogenic Amines; Brain Chemistry; Cocaine; Dopamine; Male; Mice; Mice, Inbred BALB C; Motor Activity; Phencyclidine; Receptors, Dopamine	1988
Antagonism of phencyclidine action by metaphit in rat cerebellar Purkinje neurons: an electrophysiological study. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:8 Topics: Action Potentials; Animals; gamma-Aminobutyric Acid; Male; Phencyclidine; Purkinje Cells; Rats	1986
Interactions of phencyclidine with hippocampal circuitry: evidence for neuronal heterogeneity. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:5 Topics: Action Potentials; Animals; Hippocampus; Male; Neurons; Phencyclidine; Rats; Rats, Inbred Strains	1986
Metaphit, a receptor acylator, inactivates cocaine binding sites in striatum and antagonizes cocaine-induced locomotor stimulation in rodents. Neuropharmacology, 1986, Volume: 25, Issue:8 Topics: Animals; Binding Sites; Cocaine; Corpus Striatum; Female; Male; Motor Activity; Phencyclidine; Rats; Rats, Inbred Strains	1986
Metaphit irreversibly inhibits [3H]threo-(+/-)-methylphenidate binding to rat striatal tissue. Journal of neurochemistry, 1987, Volume: 48, Issue:1 Topics: Animals; Corpus Striatum; Male; Methylphenidate; Phencyclidine; Rats; Rats, Inbred Strains; Synaptosomes; Tritium	1987
Metaphit amplifies long-term potentiation (LTP) in the mouse hippocampus. Life sciences, 1995, Volume: 56, Issue:6 Topics: Animals; Evoked Potentials, Auditory; Female; Hippocampus; Male; Mice; Mice, Inbred C57BL; Noise; Phencyclidine; Seizures; Time Factors	1995
Potentiation of metaphit-induced audiogenic seizures by REM sleep deprivation in rats. Physiology & behavior, 1993, Volume: 54, Issue:2 Topics: Acoustic Stimulation; Animals; Body Weight; Brain; Dose-Response Relationship, Drug; Eating; Male; Motor Activity; Phencyclidine; Rats; Rats, Wistar; Seizures; Sleep Deprivation; Sleep, REM; Social Environment	1993
Sigma receptor activation does not mediate fentanyl-induced attenuation of muscarinic coronary contraction. Anesthesia and analgesia, 1996, Volume: 82, Issue:5 Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Coronary Vessels; Cyclazocine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fentanyl; Guanidines; Haloperidol; Muscarine; Muscarinic Agonists; Narcotic Antagonists; Narcotics; Pentazocine; Phencyclidine; Piperidines; Potassium Channel Blockers; Receptors, Dopamine; Receptors, sigma; Signal Transduction; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents	1996
APH, an N-methyl-D-aspartate receptor antagonist, blocks the metaphit-induced audiogenic seizures in rats. Journal of physiology, Paris, 1997, Volume: 91, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Anticonvulsants; Convulsants; Electroencephalography; Male; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures	1997
The anticonvulsant potency of (+/-)-2-Amino-7-phosphonoheptanoic acid and (+/-)-2-amino-5-phosphonovaleric acid against metaphit-induced audiogenic seizures in rats. Pharmacological research, 1998, Volume: 38, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Anticonvulsants; Excitatory Amino Acid Antagonists; Male; Phencyclidine; Rats; Rats, Wistar; Seizures	1998
Inhibition of metaphit-induced audiogenic seizures by APV in rats. Physiological research, 1999, Volume: 48, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Epilepsy, Reflex; Male; Phencyclidine; Rats; Rats, Wistar	1999
N-Methyl-D-aspartic acid- and metaphit-induced audiogenic seizures in rat model of seizures. Pharmacological research, 2000, Volume: 42, Issue:3 Topics: Animals; Disease Models, Animal; Electroencephalography; Male; N-Methylaspartate; Phencyclidine; Rats; Rats, Wistar; Seizures	2000
The effects of delta sleep-inducing peptide on incidence and severity in metaphit-induced epilepsy in rats. Pharmacological research, 2002, Volume: 45, Issue:3 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Delta Sleep-Inducing Peptide; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Reflex; Male; Phencyclidine; Rats; Rats, Wistar; Time Factors	2002
The possible role of glutamate uptake in metaphit-induced seizures. Neurochemical research, 2003, Volume: 28, Issue:5 Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Caudate Nucleus; Dextrans; Female; Glutamic Acid; Guinea Pigs; Hippocampus; Kinetics; Male; Parietal Lobe; Phencyclidine; Seizures	2003
Delta sleep-inducing peptide and its tetrapeptide analogue alleviate severity of metaphit seizures. Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:2 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Convulsants; Delta Sleep-Inducing Peptide; Electroencephalography; Epilepsy, Reflex; Epilepsy, Tonic-Clonic; Male; Phencyclidine; Rats; Rats, Wistar; Running; Seizures	2004
Ontogenetic study of metaphit-induced audiogenic seizures in rats. Brain research. Developmental brain research, 2005, Mar-22, Volume: 155, Issue:1 Topics: Acoustic Stimulation; Age Factors; Animals; Animals, Newborn; Brain; Convulsants; Disease Models, Animal; Drug Resistance; Epilepsy, Reflex; Female; Genetic Predisposition to Disease; Male; Neural Pathways; Phencyclidine; Rats; Rats, Wistar; Reaction Time; Seizures; Synaptic Transmission	2005
sigma Receptor activation blocks potassium channels and depresses neuroexcitability in rat intracardiac neurons. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:3 Topics: Action Potentials; Animals; Calcium; Dose-Response Relationship, Drug; Guanidines; Guanosine Diphosphate; Guanosine Triphosphate; Heart; Neurons; Phencyclidine; Potassium Channels; Rats; Receptors, sigma; Thionucleotides	2005
Antiepileptic activity of delta sleep-inducing peptide and its analogue in metaphit-provoked seizures in rats. Seizure, 2005, Volume: 14, Issue:4 Topics: Acoustic Stimulation; Animals; Behavior, Animal; Delta Sleep-Inducing Peptide; Drug Interactions; Electroencephalography; Epilepsy, Reflex; Frontal Lobe; Male; Mass Spectrometry; Phencyclidine; Rats; Rats, Inbred WF; Reaction Time; Time Factors	2005
[Inhibition of metaphit-induced audiogenic seizures by 2-amino-7-phosphonoheptanoic acid]. Glas. Srpska akademija nauka i umetnosti. Odeljenje medicinskih nauka, 2002, Issue:47 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Male; Phencyclidine; Rats; Rats, Wistar; Seizures	2002
Delta-sleep-inducing peptide potentiates anticonvulsive activity of valproate against metaphit-provoked audiogenic seizure in rats. Pharmacology, 2006, Volume: 77, Issue:2 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Delta Sleep-Inducing Peptide; Drug Combinations; Epilepsy, Reflex; Male; Motor Skills; Neurotransmitter Agents; Phencyclidine; Rats; Rats, Wistar; Valproic Acid	2006
Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3 Topics: Analgesics, Opioid; Animals; Brain Ischemia; Calcium; Calcium Signaling; Cerebral Cortex; Cyclopentanes; Cytophotometry; Enzyme Inhibitors; Ethylenediamines; Female; Guanidines; Morpholines; Neurons; Pentazocine; Phencyclidine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Sodium Azide; Sodium Channel Agonists; Tetrodotoxin	2006
Valproate and delta-sleep peptide display high efficacy against metaphit-induced audiogenic seizure in rats. Acta physiologica Hungarica, 2006, Volume: 93, Issue:4 Topics: Animals; Anticonvulsants; Delta Sleep-Inducing Peptide; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Reflex; Male; Phencyclidine; Rats; Rats, Wistar; Valproic Acid	2006
Anticonvulsant, but not antiepileptic, action of valproate on audiogenic seizures in metaphit-treated rats. Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:10 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Data Interpretation, Statistical; Electrodes, Implanted; Electroencephalography; Epilepsy, Reflex; Male; Phencyclidine; Rats; Rats, Wistar; Valproic Acid	2007
Interaction of Delta sleep-inducing peptide and valproate on metaphit audiogenic seizure model in rats. Cellular and molecular neurobiology, 2007, Volume: 27, Issue:7 Topics: Animals; Anticonvulsants; Delta Sleep-Inducing Peptide; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Electroencephalography; Epilepsy, Reflex; Male; Phencyclidine; Rats; Rats, Wistar; Valproic Acid	2007
Moderate body hypothermia alleviates behavioral and EEG manifestations of audiogenic seizures in metaphit-treated rats. Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:10 Topics: Acoustic Stimulation; Animals; Behavior, Animal; Body Temperature; Brain; Disease Models, Animal; Electroencephalography; Hypothermia, Induced; Male; Phencyclidine; Rats; Rats, Wistar; Seizures	2007
Afobazole modulates neuronal response to ischemia and acidosis via activation of sigma-1 receptors. The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:1 Topics: Acidosis; Animals; Anti-Anxiety Agents; Benzimidazoles; Brain Ischemia; Calcium; Cell Survival; Cerebral Cortex; Ethylenediamines; Female; Guanidines; Indicators and Reagents; L-Lactate Dehydrogenase; Membrane Potentials; Morpholines; Narcotics; Neurons; Patch-Clamp Techniques; Pentazocine; Phencyclidine; Piperazines; Pregnancy; Rats; Receptors, sigma; Sigma-1 Receptor	2011