metaphit has been researched along with 1,3-ditolylguanidine in 4 studies
| Studies (metaphit) | Trials (metaphit) | Recent Studies (post-2010) (metaphit) | Studies (1,3-ditolylguanidine) | Trials (1,3-ditolylguanidine) | Recent Studies (post-2010) (1,3-ditolylguanidine) |
|---|---|---|---|---|---|
| 68 | 0 | 4 | 357 | 0 | 71 |
| Protein | Taxonomy | metaphit (IC50) | 1,3-ditolylguanidine (IC50) |
|---|---|---|---|
| polyadenylate-binding protein 1 | Homo sapiens (human) | 19.8 | |
| Rev | Human immunodeficiency virus 1 | 8.312 | |
| Female germline-specific tumor suppressor gld-1 | Caenorhabditis elegans | 5.205 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.036 | |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | 0.1816 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brum, JM; Estafanous, FG; Murray, PA; Schubert, A; Tsuchida, H | 1 |
| Cuevas, J; Zhang, H | 1 |
| Cuevas, J; Guerrero, WR; Herrera, Y; Katnik, C; Pennypacker, KR | 1 |
| Behensky, A; Cuevas, J; Deng, W; Katnik, C | 1 |
4 other study(ies) available for metaphit and 1,3-ditolylguanidine
| Article | Year |
|---|---|
Sigma receptor activation does not mediate fentanyl-induced attenuation of muscarinic coronary contraction.
Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Coronary Vessels; Cyclazocine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fentanyl; Guanidines; Haloperidol; Muscarine; Muscarinic Agonists; Narcotic Antagonists; Narcotics; Pentazocine; Phencyclidine; Piperidines; Potassium Channel Blockers; Receptors, Dopamine; Receptors, sigma; Signal Transduction; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
sigma Receptor activation blocks potassium channels and depresses neuroexcitability in rat intracardiac neurons.
Topics: Action Potentials; Animals; Calcium; Dose-Response Relationship, Drug; Guanidines; Guanosine Diphosphate; Guanosine Triphosphate; Heart; Neurons; Phencyclidine; Potassium Channels; Rats; Receptors, sigma; Thionucleotides | 2005 |
Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia.
Topics: Analgesics, Opioid; Animals; Brain Ischemia; Calcium; Calcium Signaling; Cerebral Cortex; Cyclopentanes; Cytophotometry; Enzyme Inhibitors; Ethylenediamines; Female; Guanidines; Morpholines; Neurons; Pentazocine; Phencyclidine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Sodium Azide; Sodium Channel Agonists; Tetrodotoxin | 2006 |
Afobazole modulates neuronal response to ischemia and acidosis via activation of sigma-1 receptors.
Topics: Acidosis; Animals; Anti-Anxiety Agents; Benzimidazoles; Brain Ischemia; Calcium; Cell Survival; Cerebral Cortex; Ethylenediamines; Female; Guanidines; Indicators and Reagents; L-Lactate Dehydrogenase; Membrane Potentials; Morpholines; Narcotics; Neurons; Patch-Clamp Techniques; Pentazocine; Phencyclidine; Piperazines; Pregnancy; Rats; Receptors, sigma; Sigma-1 Receptor | 2011 |