metallothionein and 3-aminobenzamide

metallothionein has been researched along with 3-aminobenzamide* in 1 studies

Other Studies

1 other study(ies) available for metallothionein and 3-aminobenzamide

Article	Year
Evidence of a regulatory role of the level of poly (ADP-ribose) in chromosomal proteins in metallothionein gene expression by glucocorticoids but not by heavy metals. Biochimica et biophysica acta, 1987, Nov-20, Volume: 910, Issue:2 The induction capacity of dexamethasone, a synthetic glucocorticoid, for the synthesis of metallothionein was about the same as that of 3-aminobenzamide, which is an inhibitor of ADP-ribosylation of chromosomal proteins, in cultured mouse mammary tumor cells. Both inductions of metallothionein were temporally correlated with a decrease in the amount of endogenous poly (ADP-ribose) on nonhistone high-mobility-group 14 and 17 proteins. In contrast, the extent of cadmium-induced metallothionein synthesis was 2-3-times that of dexamethasone or 3-aminobenzamide. However, cadmium had essentially no effect on de-ADP-ribosylation of these proteins. Topics: Animals; Benzamides; Cadmium; Cell Line; Chromosomes; Dexamethasone; Genes; Genes, Regulator; Kinetics; Mammary Neoplasms, Experimental; Metallothionein; Mice; Nuclear Proteins; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose	1987

Article

Year

Evidence of a regulatory role of the level of poly (ADP-ribose) in chromosomal proteins in metallothionein gene expression by glucocorticoids but not by heavy metals.

Biochimica et biophysica acta, 1987, Nov-20, Volume: 910, Issue:2

The induction capacity of dexamethasone, a synthetic glucocorticoid, for the synthesis of metallothionein was about the same as that of 3-aminobenzamide, which is an inhibitor of ADP-ribosylation of chromosomal proteins, in cultured mouse mammary tumor cells. Both inductions of metallothionein were temporally correlated with a decrease in the amount of endogenous poly (ADP-ribose) on nonhistone high-mobility-group 14 and 17 proteins. In contrast, the extent of cadmium-induced metallothionein synthesis was 2-3-times that of dexamethasone or 3-aminobenzamide. However, cadmium had essentially no effect on de-ADP-ribosylation of these proteins.

Topics: Animals; Benzamides; Cadmium; Cell Line; Chromosomes; Dexamethasone; Genes; Genes, Regulator; Kinetics; Mammary Neoplasms, Experimental; Metallothionein; Mice; Nuclear Proteins; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose

1987