Page last updated: 2024-09-03

met-enkephalinamide and naloxone

met-enkephalinamide has been researched along with naloxone in 11 studies

Compound Research Comparison

Studies
(met-enkephalinamide)
Trials
(met-enkephalinamide)
Recent Studies (post-2010)
(met-enkephalinamide)
Studies
(naloxone)
Trials
(naloxone)
Recent Studies (post-2010) (naloxone)
380120,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomymet-enkephalinamide (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's3 (27.27)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Renaud, FL; Roman, M; Salaman, A; Silva, WI1
Fuchs, BA; Loveless, SE; Munson, AE; Sikorski, EE; Srisuchart, B1
Chung, JM; Kim, J; Shin, HK; Willcockson, WS; Willis, WD1
Beckman, AL; Sartin, NF; Stanton, TL1
Duggan, AW; Zhao, ZQ1
Curtis, DR; Leah, JD; Malik, R1
Goh, JW; Sastry, BR1
Gilly, H; Pauser, G; Sodipo, JO1
Pauser, G1
Carpenter, DO; Elekes, K; Kemenes, G; Leung, M; Rózsa, KS; Salánki, J; Stefano, G1
Endoh, T; Suzuki, T1

Other Studies

11 other study(ies) available for met-enkephalinamide and naloxone

ArticleYear
Effect of chronic opioid treatment on phagocytosis in Tetrahymena.
    Neuropeptides, 1990, Volume: 16, Issue:3

    Topics: Animals; Drug Tolerance; Enkephalin, Methionine; Morphine; Naloxone; Phagocytosis; Tetrahymena; Time Factors

1990
Antitumor activity of enkephalin analogues in inhibiting PYB6 tumor growth in mice and immunological effects of methionine enkephalinamide.
    International journal of immunopharmacology, 1989, Volume: 11, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Antineoplastic Agents; Enkephalin, Methionine; Enkephalins; Female; Fibrosarcoma; Killer Cells, Natural; Lymphocyte Activation; Mice; Naloxone; Receptors, Opioid; Tumor Cells, Cultured

1989
Actions of opioids on primate spinothalamic tract neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1986, Volume: 6, Issue:9

    Topics: Animals; Dynorphins; Enkephalin, Methionine; Macaca fascicularis; Morphine; Naloxone; Narcotics; Neurons; Phenazocine; Phencyclidine; Spinal Cord; Thalamus

1986
Changes in body temperature and metabolic rate following microinjection of Met-enkephalinamide in the preoptic/anterior hypothalamus of rats.
    Regulatory peptides, 1985, Nov-28, Volume: 12, Issue:4

    Topics: Animals; Behavior, Animal; Body Temperature; Dose-Response Relationship, Drug; Enkephalin, Methionine; Male; Metabolic Clearance Rate; Microinjections; Naloxone; Preoptic Area; Rats; Rats, Inbred Strains; Thiorphan; Tiopronin

1985
Microelectrophoretic administration of naloxone near motoneurones fails to reproduce the effects of systemic naloxone in anaesthetized cats.
    Neuroscience letters, 1984, Apr-06, Volume: 45, Issue:3

    Topics: Animals; Cats; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Hindlimb; Membrane Potentials; Motor Neurons; Muscles; Naloxone; Neural Inhibition; Reflex, Stretch; Spinal Cord; Synaptic Transmission

1984
The effects of naloxone, morphine and methionine enkephalinamide on Ia afferent terminations in the cat spinal cord.
    Brain research, 1984, Jun-15, Volume: 303, Issue:2

    Topics: Afferent Pathways; Animals; Bicuculline; Cats; Electric Stimulation; Enkephalin, Methionine; gamma-Aminobutyric Acid; Morphine; Muscles; Naloxone; Piperidines; Procaine; Reflex, Monosynaptic; Synapses

1984
Actions of morphine and met-enkephalin-amide on nociceptor driven neurones in substantia gelatinosa and deeper dorsal horn.
    Neuropharmacology, 1983, Volume: 22, Issue:1

    Topics: Action Potentials; Animals; Cats; Electric Stimulation; Enkephalin, Methionine; Microelectrodes; Morphine; Naloxone; Neurons; Nociceptors; Spinal Cord; Substantia Gelatinosa

1983
Endorphins: mechanism of acupuncture analgesia.
    The American journal of Chinese medicine, 1981,Autumn, Volume: 9, Issue:3

    Topics: Acupuncture Therapy; Analgesia; Animals; Cats; Endorphins; Enkephalin, Methionine; Female; Male; Naloxone; Neurons, Afferent; Nociceptors; Peroneal Nerve; Tibial Nerve

1981
[Possible mechanisms of peripheral stimulation analgesia. Neurophysiologic and neuropharmacologic studies].
    Fortschritte der Medizin, 1981, Sep-03, Volume: 99, Issue:33

    Topics: Acupuncture Therapy; Animals; Cats; Endorphins; Enkephalin, Methionine; Enkephalins; Naloxone; Nociceptors

1981
Opioid peptides in the nervous system of Aplysia: a combined biochemical, immunocytochemical, and electrophysiological study.
    Cellular and molecular neurobiology, 1995, Volume: 15, Issue:2

    Topics: Analgesics, Opioid; Animals; Aplysia; Dose-Response Relationship, Drug; Electrophysiology; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ganglia, Invertebrate; Immunohistochemistry; Membrane Potentials; Naloxone; Narcotic Antagonists; Neurons; Organ Specificity; Patch-Clamp Techniques; Receptors, Opioid

1995
The effects of delta-opioid receptor agonists on synaptic transmission in hamster submandibular ganglion.
    The Bulletin of Tokyo Dental College, 1995, Volume: 36, Issue:2

    Topics: Animals; Autonomic Fibers, Preganglionic; Cricetinae; Dimethylphenylpiperazinium Iodide; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Ganglia, Parasympathetic; Ganglionic Stimulants; Naloxone; Narcotic Antagonists; Presynaptic Terminals; Receptors, Opioid, delta; Submandibular Gland; Synaptic Transmission

1995