mesulergine has been researched along with ketanserin in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (9.62) | 18.7374 |
| 1990's | 30 (57.69) | 18.2507 |
| 2000's | 8 (15.38) | 29.6817 |
| 2010's | 9 (17.31) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glennon, RA | 1 |
| Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J | 1 |
| Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP | 1 |
| Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB | 1 |
| Brown, AM; Collin, LL; Ellis, CE; Forbes, IT; Gittins, SA; Gloger, I; Hagan, J; Middlemiss, DN; Riley, G; Thomas, DR | 1 |
| Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO | 1 |
| Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R | 1 |
| Caliendo, G; De Angelis, F; Esposito, A; Fiorino, F; Frecentese, F; Magli, E; Massarelli, P; Nencini, C; Perissutti, E; Santagada, V; Severino, B; Viti, B | 1 |
| Budillon, A; Caliendo, G; De Angelis, F; Di Cintio, A; Di Gennaro, E; Esposito, A; Fiorino, F; Frecentese, F; Incisivo, GM; Magli, E; Massarelli, P; Nencini, C; Perissutti, E; Santagada, V; Severino, B | 1 |
| Caliendo, G; Ciano, A; Esposito, A; Fiorino, F; Frecentese, F; Incisivo, GM; Magli, E; Massarelli, P; Nencini, C; Perissutti, E; Santagada, V; Severino, B | 1 |
| Bielenica, A; Caliendo, G; Capasso, R; Ciano, A; Corvino, A; Di Vaio, P; Fiorino, F; Frecentese, F; Izzo, AA; Kędzierska, E; Magli, E; Massarelli, P; Nencini, C; Orzelska-Gòrka, J; Perissutti, E; Rossi, I; Santagada, V; Severino, B | 1 |
| Bielenica, A; Corvino, A; Fiorino, F; Kędzierska, E; Kmiecik, S; Koliński, A; Koliński, M; Kozioł, AE; Magli, E; Massarelli, P; Rossi, I; Sawczenko, A; Severino, B; Struga, M | 1 |
| Caliendo, G; Capasso, R; Ciano, A; Corvino, A; Di Vaio, P; Fiorino, F; Frecentese, F; Izzo, AA; Kędzierska, E; Kotlińska, JH; Magli, E; Massarelli, P; Orzelska-Gòrka, J; Perissutti, E; Rossi, I; Saccone, I; Santagada, V; Severino, B | 1 |
| Choudhary, MS; Craigo, S; Roth, BL | 2 |
| Griebel, G; Haefely, WE; Jenck, F; Martin, JR; Moreau, JL; Widmer, U | 1 |
| Bartyzel, P; Glennon, RA; Leonhardt, S; Raghupathi, R; Teitler, M | 1 |
| Dahlgren, IL; Klint, T; Larsson, K | 1 |
| Adham, N; Branchek, TA; Hartig, PR; Kao, HT; Olsen, MA; Weinshank, RL | 1 |
| Gershon, MD; Hsiung, SC; Kirchgessner, AL; Liu, KP; Tamir, H; Yu, PY | 1 |
| Canton, H; Colpaert, FC; Verrièle, L | 1 |
| Brazell, C; Dourish, CT; King, BH; Middlemiss, DN | 1 |
| Engel, G; Hoyer, D; Kalkman, HO | 1 |
| Hoyer, D; Palacios, JM; Pazos, A; Probst, A | 1 |
| Hoyer, D; Palacios, JM; Pazos, A | 1 |
| Fiorella, D; Johnson, RG; Rabin, RA | 1 |
| Grignaschi, G; Samanin, R; Sironi, F | 1 |
| Katusić, ZS; Krstić, MK | 1 |
| Grotewiel, MS; Sanders-Bush, E | 1 |
| Sillar, KT; Wedderburn, JF | 1 |
| Doble, A; Flamand, F; Malgouris, C | 1 |
| Aulakh, CS; Hulihan-Giblin, BA; Mazzola-Pomietto, P; Murphy, DL | 1 |
| Almaula, N; Ballesteros, JA; Ebersole, BJ; Sealfon, SC; Weinstein, H | 1 |
| Hartman, JL; Northup, JK | 1 |
| Carey, JE; Chen, C; Elliott, JM; Flanigan, TP; Kumar, C; McDonald, B; Newberry, NR; Newton, RA; Phipps, SL | 1 |
| Cadavid, MI; Calleja, JM; Dominguez, R; Honrubia, MA; Loza, MI; Lozoya, E; Maayani, S; Manaut, F; Rodriguez, J; Sanz, F; Seijas, JA; Villaverde, MC | 1 |
| Cenarruzabeitia, E; Del Rio, J; Lasheras, B; Ramírez, MJ | 1 |
| Elliott, JM; Newton, RA | 1 |
| López-Giménez, JF; Mengod, G; Palacios, JM; Vilaró, MT | 3 |
| Alloui, A; Bardin, L; Chassaing, C; Courade, JP; Eschalier, A | 1 |
| Brunden, K; Doucette, C; Graham, E; Hanniford, D; Harrington, J; Poole, MF; Sherf, B; Song, J; Stricker-Krongrad, A; Ting, A | 1 |
| Hietala, J; Laakso, A; Majasuo, H; Pälvimäki, EP; Penttilä, J; Syvälahti, E | 1 |
| Bell, W; Deng, C; du Bois, TM; Huang, XF | 1 |
| Booth, RG; Kondabolu, K; Kuipers, A; Morgan, D; Robertson, KL; Rowland, NE; Sakhuja, R | 1 |
| Andreeva, LA; Khashaba, EY; Kost, NV; Meshavkin, VK; Myasoedov, NF; Sokolov, OY; Voevodina, ME; Zolotarev, YA | 1 |
1 review(s) available for mesulergine and ketanserin
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
51 other study(ies) available for mesulergine and ketanserin
| Article | Year |
|---|---|
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1993 |
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection | 1993 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid | 1997 |
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine | 1998 |
Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719.
Topics: Adenylyl Cyclases; Cell Line; Cloning, Molecular; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Piperidines; Protein Binding; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Sulfonamides | 1998 |
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution | 2001 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles | 2005 |
Physical binding pocket induction for affinity prediction.
Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A | 2009 |
Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands.
Topics: Animals; Combinatorial Chemistry Techniques; Drug Evaluation, Preclinical; Indoles; Ligands; Male; Microwaves; Piperazine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin | 2010 |
Synthesis of 1-naphtylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents.
Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Ligands; Male; Molecular Structure; Naphthalenes; Piperazines; Prostatic Neoplasms; Receptor, Serotonin, 5-HT1A; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
New potent 5-HT(2A) receptor ligands containing an N'-cyanopicolinamidine nucleus: Synthesis and in vitro pharmacological evaluation.
Topics: Amides; Animals; Drug Design; Ligands; Male; Picolinic Acids; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Stereoisomerism; Substrate Specificity | 2012 |
Synthesis, in vitro and in vivo pharmacological evaluation of serotoninergic ligands containing an isonicotinic nucleus.
Topics: Animals; Body Temperature; Humans; Ligands; Locomotion; Male; Mice; Niacinamide; Piperazine; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A | 2016 |
5-HT2 receptor affinity, docking studies and pharmacological evaluation of a series of 1,3-disubstituted thiourea derivatives.
Topics: Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Male; Mice; Molecular Docking Simulation; Protein Binding; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2C; Thiourea | 2016 |
New 5-HT
Topics: Animals; Binding Sites; Biological Assay; Ileum; Ligands; Maze Learning; Molecular Structure; Picolines; Protein Binding; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists | 2017 |
Identification of receptor domains that modify ligand binding to 5-hydroxytryptamine2 and 5-hydroxytryptamine1c serotonin receptors.
Topics: Base Sequence; Binding, Competitive; Ergolines; Haloperidol; In Vitro Techniques; Ketanserin; Molecular Sequence Data; Oligodeoxyribonucleotides; Receptors, Serotonin; Recombinant Fusion Proteins; Spiperone; Structure-Activity Relationship; Transfection | 1992 |
Behavioral profile of the 5HT1A receptor antagonist (S)-UH-301 in rodents and monkeys.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Brain; Cerebral Ventricles; Conditioning, Operant; Conflict, Psychological; Ergolines; Exploratory Behavior; Feeding Behavior; Injections, Intraventricular; Ketanserin; Learning; Mice; Mice, Inbred DBA; Motor Activity; N-Methylaspartate; Rats; Receptors, Serotonin; Seizures; Serotonin; Serotonin Antagonists | 1992 |
Binding of phenylalkylamine derivatives at 5-HT1C and 5-HT2 serotonin receptors: evidence for a lack of selectivity.
Topics: Animals; Binding Sites; Binding, Competitive; Ergolines; Ketanserin; Male; Molecular Structure; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Structure-Activity Relationship; Tritium | 1992 |
The selective 5-HT2 receptor antagonist amperozide attenuates 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane-induced inhibition of male rat sexual behavior.
Topics: Alprenolol; Amphetamines; Animals; Ergolines; Ketanserin; Male; Piperazines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Sexual Behavior, Animal | 1992 |
Site-directed mutagenesis of a single residue changes the binding properties of the serotonin 5-HT2 receptor from a human to a rat pharmacology.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; DNA; Ergolines; Humans; Ketanserin; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Serotonin; Sequence Homology, Nucleic Acid; Species Specificity; Transfection | 1992 |
Identification of serotonin receptors recognized by anti-idiotypic antibodies.
Topics: Androstadienes; Animals; Antibodies, Anti-Idiotypic; Antiparkinson Agents; Brain; Carrier Proteins; Cell Line; Chromatography, Affinity; Enzyme-Linked Immunosorbent Assay; Ergolines; Fibroblasts; Fluorescent Antibody Technique; HeLa Cells; Humans; Immunohistochemistry; Iodine Radioisotopes; Iodocyanopindolol; Ketanserin; Mineralocorticoid Receptor Antagonists; Pindolol; Rabbits; Receptors, Serotonin; Serotonin; Thyroid Neoplasms; Tritium | 1991 |
Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sites.
Topics: Animals; Antipsychotic Agents; Binding Sites; Choroid Plexus; Clozapine; Ergolines; In Vitro Techniques; Ketanserin; Kinetics; Receptors, Serotonin; Swine | 1990 |
MK-212 increases rat plasma ACTH concentration by activation of the 5-HT1C receptor subtype.
Topics: Adrenocorticotropic Hormone; Animals; Antiparkinson Agents; Ergolines; Ketanserin; Male; Metergoline; Pindolol; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1989 |
Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (-)[125I]iodocyanopindolol, [3H]mesulergine and [3H]ketanserin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Choroid Plexus; Ergolines; In Vitro Techniques; Iodocyanopindolol; Ketanserin; Male; Membranes; Pindolol; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Swine; Tetrahydronaphthalenes | 1985 |
Serotonin receptors in the human brain. II. Characterization and autoradiographic localization of 5-HT1C and 5-HT2 recognition sites.
Topics: Aged; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Cerebral Cortex; Choroid Plexus; Ergolines; Female; Humans; Ketanserin; Male; Membranes; Middle Aged; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Swine; Tissue Distribution; Tritium | 1986 |
Mesulergine, a selective serotonin-2 ligand in the rat cortex, does not label these receptors in porcine and human cortex: evidence for species differences in brain serotonin-2 receptors.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Ergolines; Humans; In Vitro Techniques; Ketanserin; Kinetics; Ligands; Male; Piperidines; Rats; Receptors, Serotonin; Species Specificity; Swine; Tritium | 1984 |
Effects of chronic cocaine administration on the serotonergic system in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Cocaine; Ergolines; Hydroxyindoleacetic Acid; Ketanserin; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin | 1993 |
The 5-HT1B receptor mediates the effect of d-fenfluramine on eating caused by intra-hypothalamic injection of neuropeptide Y.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Drug Interactions; Eating; Ergolines; Fenfluramine; Hyperphagia; Hypothalamus; Injections, Intraperitoneal; Injections, Subcutaneous; Ketanserin; Male; Metergoline; Neuropeptide Y; Paraventricular Hypothalamic Nucleus; Pindolol; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Antagonists | 1995 |
Further evidence that the tachycardiac response to 5-hydroxytryptamine in rats is not mediated via typical 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Ergolines; Female; Heart Rate; Ketanserin; Male; Methiothepin; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin | 1994 |
Regulation of serotonin2A receptors in heterologous expression systems.
Topics: 3T3 Cells; Animals; Antiparkinson Agents; Binding, Competitive; Cell Line; Dogs; DOM 2,5-Dimethoxy-4-Methylamphetamine; Ergolines; Gene Expression Regulation; Ketanserin; Kidney; Kinetics; Mice; Pituitary Neoplasms; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1994 |
Modulation of rhythmic swimming activity in post-embryonic Xenopus laevis tadpoles by 5-hydroxytryptamine acting at 5HT1a receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Cyproheptadine; Ergolines; Ketanserin; Metamorphosis, Biological; Methysergide; Motor Activity; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming; Xenopus laevis | 1994 |
Autoradiographic studies of RP 62203, a potent 5-HT2 receptor antagonist. In vitro and ex vivo selectivity profile.
Topics: Animals; Antiparkinson Agents; Autoradiography; Cerebellum; Choroid Plexus; Cyclic S-Oxides; Ergolines; Guinea Pigs; In Vitro Techniques; Ketanserin; Male; Naphthalenes; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Serotonin Antagonists; Thalamus | 1993 |
A single point mutation (Phe340-->Leu340) of a conserved phenylalanine abolishes 4-[125I]iodo-(2,5-dimethoxy)phenylisopropylamine and [3H]mesulergine but not [3H]ketanserin binding to 5-hydroxytryptamine2 receptors.
Topics: Amino Acid Sequence; Amphetamines; Animals; Base Sequence; Cell Line, Transformed; Chlorocebus aethiops; Ergolines; Hydrolysis; Ketanserin; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylinositols; Point Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Lack of cross-tolerance for hypophagia induced by DOI versus m-CPP suggests separate mediation by 5-HT2A and 5-HT2C receptors, respectively.
Topics: Amphetamines; Animals; Binding, Competitive; Drug Tolerance; Eating; Ergolines; Frontal Lobe; Injections, Intraperitoneal; Ketanserin; Male; Piperazines; Propane; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Time Factors | 1995 |
Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors: direct and indirect effects on ligand affinity mediated by the same locus.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Ergolines; Hallucinogens; Humans; Ketanserin; Kinetics; Ligands; Lysergic Acid Diethylamide; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylinositols; Point Mutation; Protein Structure, Secondary; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Transfection | 1996 |
Functional reconstitution in situ of 5-hydroxytryptamine2c (5HT2c) receptors with alphaq and inverse agonism of 5HT2c receptor antagonists.
Topics: Animals; Binding, Competitive; Cattle; Cell Line; Decapodiformes; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Ketanserin; Mianserin; Photoreceptor Cells, Invertebrate; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Cell Surface; Receptors, Serotonin; Recombinant Proteins; Serotonin | 1996 |
Characterisation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors expressed in the human neuroblastoma cell line SH-SY5Y: comparative stimulation by hallucinogenic drugs.
Topics: Adrenergic alpha-Agonists; Amphetamines; Antiparkinson Agents; Calcium; Choroid Plexus; Electrophysiology; Ergolines; Ergotamine; Frontal Lobe; Hallucinogens; Humans; Hydrolysis; Ketanserin; Lysergic Acid Diethylamide; Mescaline; Methoxydimethyltryptamines; Neuroblastoma; Phosphatidylinositols; Piperazines; Quipazine; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium; Tumor Cells, Cultured | 1996 |
Synthesis, affinity at 5-HT2A, 5-HT2B and 5-HT2C serotonin receptors and structure-activity relationships of a series of cyproheptadine analogues.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Choroid Plexus; Cyproheptadine; Ergolines; Gastric Fundus; In Vitro Techniques; Ketanserin; Kinetics; Male; Models, Molecular; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Swine | 1997 |
5-HT2 receptor regulation of acetylcholine release induced by dopaminergic stimulation in rat striatal slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Benzazepines; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Ergolines; Haloperidol; In Vitro Techniques; Ketanserin; Male; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Physalaemin; Potassium; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Substance P | 1997 |
Mianserin-induced down-regulation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors stably expressed in the human neuroblastoma cell line SH-SY5Y.
Topics: Cell Membrane; DNA, Complementary; Down-Regulation; Ergolines; Humans; Ketanserin; Kinetics; Mianserin; Neuroblastoma; Phosphatidylinositols; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serotonin; Time Factors; Transfection; Tumor Cells, Cultured | 1997 |
Selective visualization of rat brain 5-HT2A receptors by autoradiography with [3H]MDL 100,907.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Cyclic S-Oxides; Ergolines; Fluorobenzenes; Guanylyl Imidodiphosphate; In Situ Hybridization; In Vitro Techniques; Ketanserin; Male; Naphthalenes; Piperidines; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists | 1997 |
[3H]MDL 100,907 labels 5-HT2A serotonin receptors selectively in primate brain.
Topics: Aged; Aged, 80 and over; Animals; Binding Sites; Binding, Competitive; Brain; Cyclic S-Oxides; Ergolines; Female; Fluorobenzenes; Humans; In Situ Hybridization; Ketanserin; Macaca fascicularis; Male; Naphthalenes; Piperidines; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Tritium | 1998 |
5-HT receptor subtypes involved in the spinal antinociceptive effect of acetaminophen in rats.
Topics: Acetaminophen; Analgesics; Animals; Ergolines; Granisetron; Injections, Spinal; Ketanserin; Male; Pain Threshold; Penbutolol; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Time Factors; Vocalization, Animal | 2001 |
Development of homogeneous high-affinity agonist binding assays for 5-HT2 receptor subtypes.
Topics: Amphetamines; Binding, Competitive; Calcium Signaling; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ergolines; Humans; Ketanserin; Lysergic Acid Diethylamide; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 2005 |
Combined treatment with citalopram and buspirone: effects on serotonin 5-HT2A and 5-HT2C receptors in the rat brain.
Topics: Amphetamines; Animals; Anti-Anxiety Agents; Antidepressive Agents; Autoradiography; Brain Chemistry; Buspirone; Cerebral Cortex; Choroid Plexus; Citalopram; Ergolines; Hydrolysis; Image Processing, Computer-Assisted; Ketanserin; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists | 2006 |
Fatty acids differentially affect serotonin receptor and transporter binding in the rat brain.
Topics: Analysis of Variance; Animals; Brain; Ergolines; Fatty Acids; Ketanserin; Male; Paroxetine; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 2006 |
Molecular and behavioral pharmacology of two novel orally-active 5HT2 modulators: potential utility as antipsychotic medications.
Topics: Amphetamines; Animals; Antipsychotic Agents; Cell Line, Transformed; Dose-Response Relationship, Drug; Ergolines; Food Preferences; Glycolates; Head Movements; Humans; Ketanserin; Mice; Mice, Inbred C57BL; Motor Activity; Protein Binding; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium | 2013 |
Multiple conformations of 5-HT2A and 5-HT 2C receptors in rat brain: an autoradiographic study with [125I](±)DOI.
Topics: Aminopyridines; Animals; Autoradiography; Brain; Ergolines; Indoles; Ketanserin; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin | 2013 |
Neurotensin-like peptides as potential antipsychotics: modulation of the serotonin system.
Topics: Animals; Antipsychotic Agents; Cell Membrane; Ergolines; Frontal Lobe; Ketanserin; Male; Mice; Neurotensin; Oligopeptides; Piperazines; Platelet Aggregation; Radioligand Assay; Rats; Serotonin; Serotonin Antagonists; Statistics, Nonparametric | 2014 |