mesulergine has been researched along with ergoline in 212 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (33.02) | 18.7374 |
| 1990's | 100 (47.17) | 18.2507 |
| 2000's | 31 (14.62) | 29.6817 |
| 2010's | 11 (5.19) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beauchamp, RD; Greeley, GH; Ishizuka, J; Thompson, JC; Townsend, CM | 1 |
| Esterle, TM; Sanders-Bush, E | 1 |
| Gorospe, E; Hoffman, BJ; Leonhardt, S; Teitler, M | 1 |
| Donatsch, P; Ettlin, RA; Prentice, DE; Qureshi, S; Siegel, RA | 1 |
| Pawlikowski, M; Pisarek, H; Stepien, H | 1 |
| Aulakh, CS; Hill, JL; Murphy, DL | 1 |
| Choudhary, MS; Craigo, S; Roth, BL | 2 |
| Crompton, MR; De Paermentier, F; Horton, RW; Lowther, S | 1 |
| Griebel, G; Haefely, WE; Jenck, F; Martin, JR; Moreau, JL; Widmer, U | 1 |
| Havlik, S; Peroutka, SJ | 1 |
| Emanuelsson, H | 1 |
| Bartyzel, P; Glennon, RA; Leonhardt, S; Raghupathi, R; Teitler, M | 1 |
| Murthy, JN; Pluchino, RS; Pranzatelli, MR | 1 |
| Pisarek, H; Stepien, H | 1 |
| Dahlgren, IL; Klint, T; Larsson, K | 1 |
| Miller, KJ; Teitler, M | 1 |
| Adham, N; Branchek, TA; Hartig, PR; Kao, HT; Olsen, MA; Weinshank, RL | 1 |
| Breeding, M; Sanders-Bush, E | 1 |
| Kagaya, A; Mikuni, M; Takahashi, K | 1 |
| Katoh, F; Kuroda, Y; Mikuni, M; Takahashi, K | 1 |
| Boulenguez, P; Chauveau, J; Delaage, M; Lanoir, J; Morel, A; Segu, L | 1 |
| Brown, AM; Kaumann, AJ; Patch, TL | 1 |
| Hicks, PB; Young, KA; Zavodny, R | 1 |
| Gershon, MD; Hsiung, SC; Kirchgessner, AL; Liu, KP; Tamir, H; Yu, PY | 1 |
| Robertson, DW; Threlkeld, PG; Wong, DT | 1 |
| McQuade, RD; Taylor, LA; Tedford, CE | 1 |
| Goldstein, M; Gopinathan, G; Lieberman, AN; Pasternack, P | 1 |
| Canton, H; Colpaert, FC; Verrièle, L | 1 |
| Lucot, JB | 1 |
| Pranzatelli, MR | 1 |
| Axel, R; Huang, KN; Jessell, TM; Julius, D; Livelli, TJ | 1 |
| Le, H; Lübbert, H; Mengod, G; Nguyen, H; Palacios, JM; Waeber, C | 1 |
| Hamik, A; Peroutka, SJ; Switzer, JA | 1 |
| Herrick-Davis, K; Titeler, M | 2 |
| Palacios, JM; Waeber, C | 1 |
| Dietl, MM; Hoyer, D; Palacios, JM; Waeber, C | 1 |
| Brazell, C; Dourish, CT; King, BH; Middlemiss, DN | 1 |
| Chojnacka-Wójcik, E; Jaros, T; Kłodzińska, A; Maj, J | 1 |
| Chiodini, PG; Dallabonzana, D; Liuzzi, A; Oppizzi, G; Verde, GG | 1 |
| Glennon, RA; McKenney, JD; Pierson, ME | 1 |
| Curzon, G; Kennett, GA | 1 |
| Engel, G; Hoyer, D; Kalkman, HO | 1 |
| Hoyer, D; Palacios, JM; Pazos, A; Probst, A | 1 |
| Heuring, RE; Peroutka, SJ | 1 |
| Palacios, JM; Pazos, A; Probst, A | 1 |
| Goldstein, M; Gopinathan, G; Lieberman, AN; Neophytides, A | 1 |
| Huang, JC; Peroutka, SJ | 1 |
| Amedro, J; Brown, L; Smith, D; Williams, G | 1 |
| Hoyer, D; Palacios, JM; Pazos, A; Probst, A; Waeber, C | 1 |
| Hoyer, D; Palacios, JM; Schoeffter, P; Waeber, C | 1 |
| Markstein, R; Palacios, JM; Pazos, A | 1 |
| Rinne, UK | 2 |
| Churg, A; Fleetham, JA; McElvaney, NG; Wilcox, PG | 1 |
| Lang, AE | 1 |
| Begaud, B; Dang Tran, L; Montastruc, JL; Montastruc, P | 1 |
| Dupont, E; Jakobsen, J; Mikkelsen, B | 1 |
| Crosignani, PG; Ferrari, C | 1 |
| Lees, AJ; Stern, GM; Wright, A | 1 |
| Chang, RJ; Goodman, LA; Hesla, JS; Molitch, ME; Rodman, EF | 1 |
| Ståhle, L; Ungerstedt, U | 1 |
| Montastruc, JL; Rascol, A; Rascol, O; Senard, JM | 1 |
| Engel, G; Hoyer, D; Palacios, JM; Pazos, A; Srivatsa, S | 1 |
| Blackwell, RE | 1 |
| Jankovic, J; Jansson, B; Orman, J | 1 |
| Pfeiffer, RF | 1 |
| Buchhave, J; Eskildsen, PC; Hommel, E | 1 |
| Glaeske, C; Pfeiffer, RF; Wilken, K | 1 |
| Bratty, PJ; Burton, K; Calne, DB; Larsen, TA; Martin, WR; Robinson, RG; Schulzer, M | 1 |
| Buvat, J; Dewailly, D; Fossati, P; Fourlinnie, JC; Lemaitre, G; Mazzuca, M; Thomas, P; Wemeau, JL | 1 |
| Pepperell, RJ | 1 |
| Gopinathan, G; Lieberman, AN; Neophytides, A | 1 |
| Hietanen, M; Huttunen, J; Teräväinen, H | 1 |
| Agnati, L; Fuxe, K; Goldstein, M; Helmer-Matyjek, E; Kuga, S; Mascagni, F | 1 |
| Baas, H; Fischer, PA; Japp, G; Schneider, E | 2 |
| Besser, GM; Bouloux, PM; Grossman, A; Loneragan, R; Rees, LH; Wass, JA | 1 |
| Adams, CB; Besser, GM; Charlesworth, M; Doniach, I; Grossman, A; Ross, R; Wass, JA | 1 |
| Brabant, G; Brennecke, I; Friedrich, H; Herrmann, H; Hesch, RD; von zur Mühlen, A; Wagner, TO | 1 |
| Burton, K; Calne, DB | 1 |
| Enz, A | 1 |
| Bystritsky, A; Engel, J; Goldstein, M; Lieberman, A; Mino, S; Regev, I | 1 |
| Closse, A; Jaton, AL | 1 |
| Esplugues, J; Morales-Olivas, FJ; Palop, V; Rubio, E | 1 |
| Jellinger, K | 1 |
| Biesemeyer, H; Ludin, HP; Ringwald, E | 1 |
| Markstein, R | 1 |
| Beckman, J; Burton, K; Calne, DB; Martin, WR | 1 |
| Jensen, I; Pakkenberg, H | 1 |
| Borges, JL; Boyett, RL; Elton, RL; Evans, WS; Kaiser, DL; MacLeod, RM; Rogol, AD; Schran, HF; Thorner, MO | 1 |
| Markó, M | 1 |
| Klÿn, JG; Lamberts, SW; Oosterom, R | 1 |
| Hoyer, D; Palacios, JM; Pazos, A | 2 |
| Donatsch, P; Enz, A; Nordmann, R | 1 |
| Agid, Y; Bonnet, AM; Esteguy, M; Guimaraes, J; Lhermitte, F | 1 |
| Fischer, PA; Hubener, K; Schneider, E | 2 |
| Kvist Poulsen, H; Møller Pedersen, S; Rasmussen, P; Riber Petersen, M | 1 |
| Closse, A | 1 |
| Reynolds, GP; Riederer, P | 1 |
| Fiorella, D; Johnson, RG; Rabin, RA | 1 |
| Fiorella, D; Rabin, RA; Winter, JC | 1 |
| Grignaschi, G; Samanin, R; Sironi, F | 1 |
| Aulakh, CS; Hulihan-Giblin, BA; Park, YD | 1 |
| Katusić, ZS; Krstić, MK | 1 |
| Hietala, J; Kuoppamäki, M; Seppälä, T; Syvälahti, E | 1 |
| de Boer, T; Klomp, J; Olijve, W; Stam, NJ; van Alebeek, C; van Delft, AM; Vanderheyden, P | 1 |
| Barker, EL; Sanders-Bush, E; Schmidt, D; Westphal, RS | 1 |
| Grotewiel, MS; Sanders-Bush, E | 1 |
| Esposito, E; Pagannone, S; Prisco, S | 1 |
| Sanders-Bush, E; Westphal, RS | 1 |
| Hietala, J; Kuoppamäki, M; Pälvimäki, EP; Syvälahti, E | 1 |
| Callahan, PM; Cunningham, KA | 1 |
| Sillar, KT; Wedderburn, JF | 1 |
| Borsini, F; Ceci, A; Cesana, R; Ciprandi, C | 1 |
| Aulakh, CS; Goldman, D; Hulihan-Giblin, BA; Park, YD | 1 |
| Gregory, CM; Pranzatelli, MR | 1 |
| Di Scala, G; Hoyer, D; Rigo, M; Rocha, B; Sandner, G | 1 |
| Davis, JM; Dubey, MP; Pandey, GN; Pandey, SC; Piano, MR; Schwertz, DW | 1 |
| Barone, P; Fillion, G; Millet, S; Moret, C; Prudhomme, N | 1 |
| Beer, MS; Hawkins, LM; Middlemiss, DN; Stanton, JA | 1 |
| Craig, DA; Martin, GR | 1 |
| Doble, A; Flamand, F; Malgouris, C | 1 |
| Briley, M; Palmier, C; Pauwels, PJ | 1 |
| Cynader, MS; Dyck, RH | 1 |
| Murthy, JN; Pranzatelli, MR; Tailor, PT | 1 |
| Bruinvels, AT; Hoyer, D; Palacios, JM | 1 |
| Aulakh, CS; Hulihan-Giblin, BA; Mazzola-Pomietto, P; Murphy, DL | 1 |
| Almaula, N; Ballesteros, JA; Ebersole, BJ; Sealfon, SC; Weinstein, H | 1 |
| Akiyoshi, J; Fujii, I; Isogawa, K; Nagayama, H; Yamada, K | 1 |
| Hartman, JL; Northup, JK | 1 |
| Kellermann, O; Launay, JM; Loric, S; Maroteaux, L | 1 |
| Hietala, J; Kuoppamäki, M; Laakso, A; Pälvimäki, EP; Syvälahti, E | 1 |
| Li, TK; Lumeng, L; Pandey, SC | 1 |
| Baron, BM; Freedman, J; Siegel, BW; Vaal, MJ | 1 |
| Cooke, BA; Dirami, G; Teerds, KJ | 1 |
| Carey, JE; Chen, C; Elliott, JM; Flanigan, TP; Kumar, C; McDonald, B; Newberry, NR; Newton, RA; Phipps, SL | 1 |
| Imada-Shirakata, Y; Kotera, T; Okuma, M; Ueda, S | 1 |
| Curtis, MJ; Ellwood, AJ | 1 |
| Cynader, MS; Gu, Q; Wang, Y | 1 |
| Cadavid, MI; Calleja, JM; Dominguez, R; Honrubia, MA; Loza, MI; Lozoya, E; Maayani, S; Manaut, F; Rodriguez, J; Sanz, F; Seijas, JA; Villaverde, MC | 1 |
| Cenarruzabeitia, E; Del Rio, J; Lasheras, B; Ramírez, MJ | 1 |
| De Vries, P; Heiligers, JP; Saxena, PR; Villalón, CM | 1 |
| Elliott, JM; Newton, RA | 1 |
| Egan, C; Herrick-Davis, K; Teitler, M | 1 |
| Castillo, MJ; Castro, ME; del Arco, C; del Olmo, E; Pazos, A; Romón, T | 1 |
| López-Giménez, JF; Mengod, G; Palacios, JM; Vilaró, MT | 4 |
| Giovannini, MG; Pepeu, G; Zhelyazkova-Savova, M | 2 |
| Boess, FG; Bourson, A; Kapps, V; Rudler, A; Sleight, AJ; Zwingelstein, C | 1 |
| Ijzerman, AP; Kuipers, W; Oliveira, L; Vriend, G | 1 |
| Grill, HJ; Kaplan, JM; Song, S | 1 |
| Belden, M; Carvey, PM; Goetz, CG; Pappert, EJ; Stebbins, GT | 1 |
| Cooke, BA; Dirami, G | 1 |
| Di Giovanni, G; Di Mascio, M; Di Matteo, V; Esposito, E | 1 |
| Couvaris, C; Daifotis, Z; Galanopoulou, P; Giannakopoulos, G | 1 |
| Centurión, D; De Vries, P; Heiligers, JP; Sánchez-López, A; Saxena, PR; Villalón, CM | 1 |
| Applegate, CD; Tecott, LH | 1 |
| Bloem, LJ; Hurley, JH; Liu, J; Pavalko, F; Simon, JR; Tian, M; Yu, L | 1 |
| Carvey, PM; Goetz, CG; Leurgans, S; Ling, ZD; Pappert, EJ; Raman, R; Vu, TQ | 1 |
| Gauthier, C; Grinde, E; Herrick-Davis, K; Teitler, M | 1 |
| Coupar, IM; Hemedah, M; Mitchelson, FJ | 2 |
| Conklin, DS; Fitzgerald, LW; Hartig, PR; Iyer, G; Kostich, WA; Krause, CM; Largent, BL; Marshall, AP; Patterson, JP; Tran, DP | 1 |
| Grinde, E; Herrick-Davis, K; Niswender, CM | 1 |
| Alberts, GL; Gill, GS; Im, WB; Pregenzer, JF; Zaworski, PG | 1 |
| Cassano, GB; Dell'Osso, L; Giannaccini, G; Lucacchini, A; Marazziti, D; Rossi, A; Zavaglia, KM | 1 |
| Barwick, VS; Hicks, PB; Jones, DH; Richter, JT; Young, KA | 1 |
| Gordon, M; Heinz-Esser, K; Kanwal, JS; Peng, JP | 1 |
| Cussac, D; Millan, MJ; Newman-Tancredi, A; Quentric, Y | 1 |
| Aloyo, VJ; Harvey, JA | 1 |
| Cordi, AA; Ragonnet, C; Vayssettes-Courchay, C; Verbeuren, TJ | 1 |
| Brotchie, JM; Fox, SH | 1 |
| Ebersole, BJ; Rosendorff, A; Sealfon, SC | 1 |
| Honda, M; Ono, H | 1 |
| Berg, KA; Clarke, WP; Cropper, JD; Emeson, RB; Niswender, CM; Sanders-Bush, E | 1 |
| Jurzak, M; Leysen, JE; Luyten, WH; Oekelen, DV; Van de Wiel, D; Van Hecke, G | 1 |
| Alberts, GL; Chio, CL; Im, WB | 1 |
| Alloui, A; Bardin, L; Chassaing, C; Courade, JP; Eschalier, A | 1 |
| Chen, Y; Hertz, L; Kong, EK; Peng, L; Yu, AC | 1 |
| Martín-Cora, FJ; Pazos, A | 1 |
| Clifton, PG; Dourish, CT; Kennett, GA; Lee, MD; Somerville, EM | 1 |
| Feuerbach, D; Loetscher, E; Mahé, C; Müller, W; Schoeffter, P; Seiler, MP | 1 |
| Christopoulos, A; Devlin, MG; Guida, E; Ryan, OM; Sexton, PM; Smith, NJ | 1 |
| Goldman, D; Iwata, N; Linnoila, M; Northup, JK; Okada, M; Ozaki, N | 1 |
| Hietala, J; Majasuo, H; Pälvimäki, EP; Syvälahti, E | 1 |
| Chathu, F; Mohanan, VV; Paulose, CS | 1 |
| Antonatos, S; Galanopoulou, P | 1 |
| Khan, R; Mohanan, VV; Paulose, CS | 1 |
| Brunden, K; Doucette, C; Graham, E; Hanniford, D; Harrington, J; Poole, MF; Sherf, B; Song, J; Stricker-Krongrad, A; Ting, A | 1 |
| Hietala, J; Laakso, A; Majasuo, H; Pälvimäki, EP; Penttilä, J; Syvälahti, E | 1 |
| Andressen, KW; Krobert, KA; Levy, FO | 1 |
| Bell, W; Deng, C; du Bois, TM; Huang, XF | 1 |
| Ackley, DC; Holbert, JK; Hu, XE; Kim, N; Klopfenstein, SR; Méndez-Andino, JL; Meyers, KM; Mitchell, MC; Mittelstadt, SW; Mumin, RN; Paris, JL; Reizes, O; Wos, JA | 1 |
| García, M; Martín, ML; Morán, A; Ortizde Urbina, AV; San Román, L | 1 |
| Krishnakumar, A; Nandhu, MS; Paulose, CS | 1 |
| Haleem, DJ; Shireen, E | 1 |
| Bönisch, H; Brüss, M; Göthert, M; Steinhagen, F; Walstab, J | 1 |
| Adams, W; van den Buuse, M | 1 |
| Haider, S; Haleem, DJ; Khaliq, S; Memon, Z; Saleem, S | 1 |
| Capuano, B; Christopoulos, A; Conway, RJ; Crosby, IT; Robertson, AD; Valant, C | 1 |
| Jahnsen, JA; Uhlén, S | 1 |
| Booth, RG; Kondabolu, K; Kuipers, A; Morgan, D; Robertson, KL; Rowland, NE; Sakhuja, R | 1 |
| Andreeva, LA; Khashaba, EY; Kost, NV; Meshavkin, VK; Myasoedov, NF; Sokolov, OY; Voevodina, ME; Zolotarev, YA | 1 |
| Andressen, KW; Brevik, CH; Krobert, KA; Levy, FO; Manfra, O; Ulsund, AH; Vanhoenacker, P | 1 |
| Bojarski, AJ; Duszyńska, B; Lenda, T; Nowak, G; Satała, G | 1 |
6 review(s) available for mesulergine and ergoline
| Article | Year |
|---|---|
Medical treatment of pituitary adenomas: effects on tumor growth.
Topics: Adenoma; Adrenocorticotropic Hormone; Bromocriptine; Dihydroergotoxine; Dopamine; Drug Administration Schedule; Ergolines; Growth Hormone; Levodopa; Lisuride; Metergoline; Methysergide; Pergolide; Pituitary Neoplasms; Prolactin; Tomography, X-Ray Computed | 1985 |
D-1 and D-2 agonists in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Dopamine; Ergolines; Female; Humans; Male; Middle Aged; Parkinson Disease; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1987 |
Update on dopamine agonists in Parkinson's disease: "beyond bromocriptine".
Topics: Antiparkinson Agents; Bromocriptine; Dopamine; Ergolines; Humans; Parkinson Disease; Piperazines | 1987 |
Medical treatment of hyperprolactinaemic disorders.
Topics: Acromegaly; Bromocriptine; Delayed-Action Preparations; Dopamine; Ergolines; Female; Humans; Hyperprolactinemia; Lisuride; Pergolide; Pituitary Neoplasms; Pregnancy; Prolactin; Psychoses, Substance-Induced; Tamoxifen | 1986 |
Diagnosis and management of prolactinomas.
Topics: Adenoma; Adult; Diagnosis, Differential; Ergolines; Female; Follow-Up Studies; Galactorrhea; Genital Diseases, Female; Humans; Hypophysectomy; Hypothyroidism; Infertility, Female; Pergolide; Pituitary Neoplasms; Pregnancy; Pregnancy Complications, Neoplastic; Prolactin; Sella Turcica; Tomography, X-Ray Computed; Visual Field Tests | 1985 |
The pharmacology of mesulergine.
Topics: Animals; Antiparkinson Agents; Ergolines; Humans; Parkinson Disease; Receptors, Dopamine | 1985 |
10 trial(s) available for mesulergine and ergoline
| Article | Year |
|---|---|
Mesulergine: a dopamine agonist with novel properties in Parkinson's disease.
Topics: Aged; Dopamine Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ergolines; Female; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease | 1990 |
Mesulergine in early Parkinson's disease: a double blind controlled trial.
Topics: Aged; Antiparkinson Agents; Benserazide; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Ergolines; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Random Allocation | 1986 |
Placebo-controlled study of mesulergine in Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Clinical Trials as Topic; Ergolines; Female; Humans; Male; Middle Aged; Parkinson Disease; Placebos | 1985 |
The effect of a new ergoline derivative, CU 32-085, in the treatment of acromegaly. A controlled study.
Topics: Acromegaly; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Ergolines; Female; Growth Hormone; Hormones; Humans; Hydrocortisone; Male; Middle Aged; Prolactin | 1985 |
Mesulergine (CU32-085) in the treatment of Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Clinical Trials as Topic; Double-Blind Method; Ergolines; Female; Humans; Male; Middle Aged; Parkinson Disease; Random Allocation | 1985 |
Parkinson's disease: a comparison of mesulergine and bromocriptine.
Topics: Adult; Aged; Bromocriptine; Clinical Trials as Topic; Ergolines; Female; Humans; Male; Middle Aged; Movement; Nervous System; Parkinson Disease | 1985 |
Treatment of human hyperprolactinaemia with a new dopamine agonist: CU 32085 (mesulergin).
Topics: Administration, Oral; Adolescent; Adult; Aged; Bromocriptine; Clinical Trials as Topic; Ergolines; Female; Gonads; Humans; Hyperprolactinemia; Male; Middle Aged; Pituitary Gland; Pituitary Neoplasms; Prolactin; Receptors, Dopamine; Tomography, X-Ray Computed | 1985 |
Mesulergine and bromocriptine in long-term treatment of advanced parkinsonism.
Topics: Adult; Aged; Blood Pressure; Bromocriptine; Drug Administration Schedule; Ergolines; Female; Heart Rate; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1985 |
Adjuvant treatment of Parkinson's disease with dopamine agonists: open trial with bromocriptine and CU 32-085.
Topics: Aged; Bromocriptine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ergolines; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Receptors, Dopamine | 1982 |
Treatment of Parkinson's disease with the ergoline derivatives CQ 32-084 and CU 32-085.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Disability Evaluation; Ergolines; Female; Humans; Male; Middle Aged; Parkinson Disease; Pilot Projects | 1983 |
196 other study(ies) available for mesulergine and ergoline
| Article | Year |
|---|---|
Receptor-mediated autocrine growth-stimulatory effect of 5-hydroxytryptamine on cultured human pancreatic carcinoid cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Division; Cyclic AMP; Cyclic GMP; Ergolines; Humans; Pancreatic Neoplasms; Pertussis Toxin; Phosphatidylinositols; Pindolol; Receptors, Serotonin; Second Messenger Systems; Serotonin; Serotonin Antagonists; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Serotonin agonists increase transferrin levels via activation of 5-HT1C receptors in choroid plexus epithelium.
Topics: Amino Acid Isomerases; Animals; Blotting, Northern; Carrier Proteins; Cells, Cultured; Choroid Plexus; Cyclosporins; Epithelium; Ergolines; Fibroblasts; Kinetics; Male; Mianserin; Peptidylprolyl Isomerase; Phosphatidylinositols; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA Probes; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Thymidine; Time Factors; Transferrin | 1992 |
Molecular pharmacological differences in the interaction of serotonin with 5-hydroxytryptamine1C and 5-hydroxytryptamine2 receptors.
Topics: 3T3 Cells; Amphetamines; Animals; Binding, Competitive; Brain; Cell Membrane; Choroid Plexus; Ergolines; Fibroblasts; GTP-Binding Proteins; Inositol Phosphates; Iodine Radioisotopes; Kinetics; Mice; Neurotransmitter Agents; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Swine; Transfection; Tritium | 1992 |
Mesulergine induced Leydig cell tumours, a syndrome involving the pituitary-testicular axis of the rat.
Topics: Animals; Dihydropyridines; Ergolines; Isradipine; Leydig Cell Tumor; Male; Pituitary Hormones; Rats; Rats, Inbred Strains; Syndrome; Testicular Hormones; Time Factors | 1992 |
Effect of mesulergine on prolactin secretion and dopamine D2 receptors-adaptive changes in diethylstilbestrol-induced hyperplasia of the rat anterior pituitary.
Topics: Animals; Antiparkinson Agents; Bromocriptine; Diethylstilbestrol; Dose-Response Relationship, Drug; Ergolines; Female; Hyperplasia; Hyperprolactinemia; Pergolide; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Receptors, Dopamine D2; Spiperone; Time Factors; Tritium | 1992 |
Effects of various serotonin receptor subtype-selective antagonists alone and on m-chlorophenylpiperazine-induced neuroendocrine changes in rats.
Topics: Animals; Corticosterone; Ergolines; Male; Metergoline; Mianserin; Neurosecretory Systems; Piperazines; Prolactin; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone | 1992 |
Identification of receptor domains that modify ligand binding to 5-hydroxytryptamine2 and 5-hydroxytryptamine1c serotonin receptors.
Topics: Base Sequence; Binding, Competitive; Ergolines; Haloperidol; In Vitro Techniques; Ketanserin; Molecular Sequence Data; Oligodeoxyribonucleotides; Receptors, Serotonin; Recombinant Fusion Proteins; Spiperone; Structure-Activity Relationship; Transfection | 1992 |
The distribution of 5-HT1D and 5-HT1E binding sites in human brain.
Topics: Adult; Aged; Antiparkinson Agents; Brain; Brain Chemistry; Ergolines; Female; Humans; In Vitro Techniques; Kinetics; Male; Membranes; Middle Aged; Pindolol; Receptors, Serotonin | 1992 |
Behavioral profile of the 5HT1A receptor antagonist (S)-UH-301 in rodents and monkeys.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Brain; Cerebral Ventricles; Conditioning, Operant; Conflict, Psychological; Ergolines; Exploratory Behavior; Feeding Behavior; Injections, Intraventricular; Ketanserin; Learning; Mice; Mice, Inbred DBA; Motor Activity; N-Methylaspartate; Rats; Receptors, Serotonin; Seizures; Serotonin; Serotonin Antagonists | 1992 |
Differential radioligand binding properties of [3H]5-hydroxytryptamine and [3H]mesulergine in a clonal 5-hydroxytryptamine1C cell line.
Topics: Animals; Antiparkinson Agents; Cell Line; Centrifugation; Clone Cells; Cold Temperature; Ergolines; Filtration; Guanosine Triphosphate; Mice; Radioligand Assay; Receptors, Serotonin; Serotonin | 1992 |
Autoradiographic localization in polychaete embryos of tritiated mesulergine, a selective antagonist of serotonin receptors that inhibits early polychaete development.
Topics: Animals; Autoradiography; Cell Division; Cell Movement; Cell Nucleus; Chromosomes; Cytoplasm; Ergolines; Gestational Age; Polychaeta; Receptors, Serotonin; Serotonin Antagonists; Tritium | 1992 |
Binding of phenylalkylamine derivatives at 5-HT1C and 5-HT2 serotonin receptors: evidence for a lack of selectivity.
Topics: Animals; Binding Sites; Binding, Competitive; Ergolines; Ketanserin; Male; Molecular Structure; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Structure-Activity Relationship; Tritium | 1992 |
Identification of spinal 5-HT1C binding sites in the rat: characterization of [3H]mesulergine binding.
Topics: Animals; Antiparkinson Agents; Binding Sites; Binding, Competitive; Ergolines; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord | 1992 |
The effect of mesulergine on prolactin secretion and anterior pituitary cells morphology in diethylstilboestrol-treated female Wistar rats.
Topics: Animals; Antiparkinson Agents; Bromocriptine; Cell Division; Diethylstilbestrol; Drug Interactions; Ergolines; Female; Hyperprolactinemia; Immunohistochemistry; Pergolide; Pituitary Gland, Anterior; Prolactin; Rats | 1992 |
The selective 5-HT2 receptor antagonist amperozide attenuates 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane-induced inhibition of male rat sexual behavior.
Topics: Alprenolol; Amphetamines; Animals; Ergolines; Ketanserin; Male; Piperazines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Sexual Behavior, Animal | 1992 |
Quantitative autoradiography of 5-CT-sensitive (5-HT1D) and 5-CT-insensitive (5-HT1E) serotonin receptors in human brain.
Topics: Antiparkinson Agents; Autoradiography; Brain Chemistry; Ergolines; Humans; In Vitro Techniques; Pindolol; Receptors, Serotonin; Serotonin | 1992 |
Site-directed mutagenesis of a single residue changes the binding properties of the serotonin 5-HT2 receptor from a human to a rat pharmacology.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; DNA; Ergolines; Humans; Ketanserin; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Serotonin; Sequence Homology, Nucleic Acid; Species Specificity; Transfection | 1992 |
Choroid plexus epithelial cells in primary culture: a model of 5HT1C receptor activation by hallucinogenic drugs.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Antiparkinson Agents; Cells, Cultured; Choroid Plexus; DOM 2,5-Dimethoxy-4-Methylamphetamine; Epithelial Cells; Ergolines; Hallucinogens; Male; Phosphatidylinositols; Quipazine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stereoisomerism | 1991 |
Modulation of 5-HT2 receptor-mediated intracellular calcium movement in platelets and its function in affective disorders.
Topics: Animals; Antiparkinson Agents; Corticosterone; Ergolines; Hippocampus; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1991 |
Rat hippocampal 5-HT1c receptor binding and 5-HT1c receptor mediated rat blood corticosterone responses.
Topics: Animals; Antiparkinson Agents; Corticosterone; Ergolines; Hippocampus; Male; Piperazines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1991 |
Pharmacological characterization of serotonin-O-carboxymethyl-glycyl-tyrosinamide, a new selective indolic ligand for 5-hydroxytryptamine (5-HT)1B and 5-HT1D binding sites.
Topics: Animals; Binding Sites; Brain; Dipeptides; Ergolines; Guinea Pigs; Male; Membranes; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium | 1991 |
The antimigraine drugs ergotamine and dihydroergotamine are potent 5-HT1C receptor agonists in piglet choroid plexus.
Topics: Animals; Binding, Competitive; Choroid Plexus; Dihydroergotamine; Ergolines; Ergotamine; In Vitro Techniques; Inositol Phosphates; Migraine Disorders; Piperazines; Receptors, Serotonin; Serotonin; Swine; Thermodynamics | 1991 |
Subchronic buspirone, mesulergine, and ICS 205-930 lack effects on D1 and D2 dopamine binding in the rat striatum during chronic haloperidol treatment.
Topics: Animals; Apomorphine; Buspirone; Corpus Striatum; Ergolines; Haloperidol; In Vitro Techniques; Indoles; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Serotonin Antagonists; Stereotyped Behavior; Tropisetron; Up-Regulation | 1991 |
Identification of serotonin receptors recognized by anti-idiotypic antibodies.
Topics: Androstadienes; Animals; Antibodies, Anti-Idiotypic; Antiparkinson Agents; Brain; Carrier Proteins; Cell Line; Chromatography, Affinity; Enzyme-Linked Immunosorbent Assay; Ergolines; Fibroblasts; Fluorescent Antibody Technique; HeLa Cells; Humans; Immunohistochemistry; Iodine Radioisotopes; Iodocyanopindolol; Ketanserin; Mineralocorticoid Receptor Antagonists; Pindolol; Rabbits; Receptors, Serotonin; Serotonin; Thyroid Neoplasms; Tritium | 1991 |
Affinities of fluoxetine, its enantiomers, and other inhibitors of serotonin uptake for subtypes of serotonin receptors.
Topics: Animals; Antidepressive Agents; Binding, Competitive; Cattle; Choroid Plexus; Ergolines; Fluoxetine; In Vitro Techniques; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stereoisomerism; Synaptosomes | 1991 |
The binding of SCH 39166 and SCH 23390 to 5-HT1C receptors in porcine choroid plexus.
Topics: Animals; Antiparkinson Agents; Benzazepines; Binding, Competitive; Choroid Plexus; Dopamine; Dopamine Antagonists; Ergolines; Receptors, Serotonin; Serotonin Antagonists; Swine | 1991 |
Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sites.
Topics: Animals; Antipsychotic Agents; Binding Sites; Choroid Plexus; Clozapine; Ergolines; In Vitro Techniques; Ketanserin; Kinetics; Receptors, Serotonin; Swine | 1990 |
Effects of serotonin antagonists on motion sickness and its suppression by 8-OH-DPAT in cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Dose-Response Relationship, Drug; Ergolines; Female; Metergoline; Motion Sickness; Piperazines; Propranolol; Serotonin Antagonists; Stereoisomerism; Tetrahydronaphthalenes | 1990 |
Neonatal 5,7-DHT lesions upregulate [3H]mesulergine-labelled spinal 5-HT1C binding sites in the rat.
Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Antiparkinson Agents; Cisterna Magna; Ergolines; Female; In Vitro Techniques; Injections; Injections, Intraperitoneal; Kinetics; Male; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spinal Cord; Up-Regulation | 1990 |
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
Topics: Amino Acid Sequence; Animals; Antiparkinson Agents; Brain; DNA; Ergolines; Fibroblasts; Gene Library; Genes; Mice; Molecular Sequence Data; Organ Specificity; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Nucleic Acid; Spiperone; Transfection; Type C Phospholipases | 1990 |
The distribution and cellular localization of the serotonin 1C receptor mRNA in the rodent brain examined by in situ hybridization histochemistry. Comparison with receptor binding distribution.
Topics: Animals; Antiparkinson Agents; Autoradiography; Blotting, Northern; Brain; Ergolines; Male; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Serotonin; RNA Probes; RNA, Messenger; Tritium | 1990 |
Identification of 5-hydroxytryptamine1D binding sites in human brain membranes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adolescent; Adult; Aged; Binding, Competitive; Caudate Nucleus; Ergolines; Frontal Lobe; Globus Pallidus; Humans; Middle Aged; Receptors, Serotonin; Subcellular Fractions; Tetrahydronaphthalenes | 1989 |
Detection and characterization of a 5HT1D serotonin receptor-GTP binding protein interaction in porcine and bovine brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Brain; Cattle; Ergolines; GTP-Binding Proteins; In Vitro Techniques; Receptors, Serotonin; Swine; Tetrahydronaphthalenes | 1989 |
Serotonin-1 receptor binding sites in the human basal ganglia are decreased in Huntington's chorea but not in Parkinson's disease: a quantitative in vitro autoradiography study.
Topics: Aged; Basal Ganglia; Ergolines; Female; Humans; Huntington Disease; Male; Middle Aged; Parkinson Disease; Receptors, Serotonin | 1989 |
5.HT1 receptors in the vertebrate brain. Regional distribution examined by autoradiography.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Animals; Autoradiography; Brain; Cats; Disease Models, Animal; Dogs; Ergolines; Female; Guinea Pigs; Humans; Macaca mulatta; Male; Mice; Movement Disorders; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Tritium | 1989 |
MK-212 increases rat plasma ACTH concentration by activation of the 5-HT1C receptor subtype.
Topics: Adrenocorticotropic Hormone; Animals; Antiparkinson Agents; Ergolines; Ketanserin; Male; Metergoline; Pindolol; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1989 |
Exploratory hypoactivity induced by m-trifluoromethylphenylpiperazine (TFMPP) and m-chlorophenylpiperazine (m-CPP).
Topics: Animals; Ergolines; Exploratory Behavior; Male; Metergoline; Mianserin; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone | 1989 |
Stimulus generalization of 1-(3-trifluoromethylphenyl)piperazine (TFMPP) to propranolol, pindolol, and mesulergine.
Topics: Adrenergic beta-Antagonists; Animals; Antiparkinson Agents; Drug Interactions; Ergolines; Generalization, Stimulus; Male; Pindolol; Piperazines; Propranolol; Rats; Rats, Inbred Strains | 1988 |
Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Ergolines; Feeding Behavior; Food Deprivation; Indoles; Male; Mianserin; Motor Activity; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1988 |
Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (-)[125I]iodocyanopindolol, [3H]mesulergine and [3H]ketanserin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Choroid Plexus; Ergolines; In Vitro Techniques; Iodocyanopindolol; Ketanserin; Male; Membranes; Pindolol; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Swine; Tetrahydronaphthalenes | 1985 |
Serotonin receptors in the human brain. II. Characterization and autoradiographic localization of 5-HT1C and 5-HT2 recognition sites.
Topics: Aged; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Cerebral Cortex; Choroid Plexus; Ergolines; Female; Humans; Ketanserin; Male; Membranes; Middle Aged; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Swine; Tissue Distribution; Tritium | 1986 |
Characterization of a novel 3H-5-hydroxytryptamine binding site subtype in bovine brain membranes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Binding, Competitive; Brain; Calcium; Cattle; Caudate Nucleus; Ergolines; Membranes; Nucleotides; Osmolar Concentration; Serotonin; Tetrahydronaphthalenes; Tritium | 1987 |
Serotonin receptors in the human brain--III. Autoradiographic mapping of serotonin-1 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aged; Aged, 80 and over; Autoradiography; Brain; Ergolines; Female; Humans; Male; Mianserin; Middle Aged; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1987 |
Identification of 5-hydroxytryptamine binding site subtypes in rat spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Binding, Competitive; Ergolines; In Vitro Techniques; Indoles; Rats; Receptors, Serotonin; Serotonin; Spinal Cord; Tetrahydronaphthalenes | 1987 |
A pharmacological analysis of the rat spinal cord serotonin (5-HT) autoreceptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Ergolines; Male; Piperazines; Potassium; Quipazine; Rats; Receptors, Serotonin; Serotonin; Spinal Cord; Spiperone; Tetrahydronaphthalenes; Tritium | 1988 |
Identification of a 5-HT1 recognition site in human brain membranes different from 5-HT1A, 5-HT1B and 5-HT1C sites.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Binding, Competitive; Brain Chemistry; Caudate Nucleus; Cerebral Cortex; Ergolines; Humans; Receptors, Serotonin; Tetrahydronaphthalenes | 1988 |
Molecular pharmacology of 5-HT1D recognition sites: radioligand binding studies in human, pig and calf brain membranes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiparkinson Agents; Brain; Cattle; Caudate Nucleus; Ergolines; Humans; In Vitro Techniques; Kinetics; Membranes; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Swine; Tetrahydronaphthalenes | 1988 |
Serotonin-1C sites in the choroid plexus are not linked in a stimulatory or inhibitory way to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cerebral Cortex; Choroid Plexus; Colforsin; Cyclic AMP; Dopamine; Ergolines; Hippocampus; Histamine; Kinetics; Mianserin; Rats; Receptors, Serotonin; Serotonin; Swine | 1986 |
Dopamine agonists as primary treatment in Parkinson's disease.
Topics: Antiparkinson Agents; Bromocriptine; Disability Evaluation; Drug Therapy, Combination; Ergolines; Humans; Levodopa; Lisuride; Long-Term Care; Parkinson Disease; Pergolide; Receptors, Dopamine | 1987 |
Pleuropulmonary disease during bromocriptine treatment of Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Bromocriptine; Ergolines; Humans; Lung Diseases; Male; Middle Aged; Parkinson Disease; Pleural Diseases; Radiography | 1988 |
Detection and characterization of the serotonin 5-HT 1D receptor in rat and human brain.
Topics: Animals; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Cerebral Cortex; Ergolines; Humans; Kinetics; Male; Middle Aged; Pindolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tissue Distribution | 1988 |
Antihypertensive effects of mesulergine: further evidence for a peripheral site of action of dopamine agonists.
Topics: Animals; Antihypertensive Agents; Antiparkinson Agents; Blood Pressure; Cisterna Magna; Dogs; Ergolines; Female; Injections; Injections, Intravenous; Male; Receptors, Dopamine | 1987 |
Mesulergine and pergolide in previously untreated Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Domperidone; Ergolines; Female; Humans; Male; Parkinson Disease; Pergolide | 1987 |
The effect of the ergoline derivative, CU 32-085, on prolactin secretion in hyperprolactinemic women.
Topics: Adenoma; Adult; Ergolines; Female; Humans; Hyperprolactinemia; Kinetics; Menstruation Disturbances; Pituitary Neoplasms; Prolactin | 1987 |
On the mode of action of six putative dopamine receptor agonists on suppression of exploratory behaviour in rats.
Topics: Animals; Bromocriptine; Ergolines; Exploratory Behavior; Habituation, Psychophysiologic; Male; Motor Activity; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1987 |
Mesulergine (CU 32-085) in the treatment of Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Drug Administration Schedule; Ergolines; Female; Humans; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors | 1986 |
[125I]LSD labels 5-HT1C recognition sites in pig choroid plexus membranes. Comparison with [3H]mesulergine and [3H]5-HT binding.
Topics: Animals; Cell Membrane; Cerebral Cortex; Choroid Plexus; Ergolines; Kinetics; Lysergic Acid Diethylamide; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin; Species Specificity; Swine | 1986 |
Management of prolactinomas. A reappraisal.
Topics: Adenoma; Bromocriptine; Ergolines; Female; Humans; Lisuride; Metergoline; Pergolide; Pituitary Neoplasms; Pregnancy; Prolactin; Radiotherapy Dosage; Radiotherapy, High-Energy; Time Factors | 1985 |
Efficacy of pergolide and mesulergine.
Topics: Aged; Antiparkinson Agents; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Ergolines; Humans; Levodopa; Middle Aged; Parkinson Disease; Pergolide | 1986 |
Initial treatment of parkinsonism with 8-alpha-amino-ergoline.
Topics: Adult; Aged; Ergolines; Female; Humans; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Psychomotor Performance | 1985 |
Central dopamine agonist activity on the 8-alpha-amino-ergoline CU 32-085.
Topics: Animals; Antiparkinson Agents; Brain; Chlorocebus aethiops; Corpus Striatum; Dopamine; Ergolines; Female; Male; Mice; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tremor | 1985 |
Three-year observation of mesulergine (CU 32-085) in advanced and newly treated parkinsonism.
Topics: Adult; Aged; Antiparkinson Agents; Bromocriptine; Drug Therapy, Combination; Ergolines; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease | 1985 |
Comparison of the clinical activity of mesulergine and pergolide in the treatment of hyperprolactinaemia.
Topics: Adenoma; Adult; Ergolines; Female; Humans; Male; Middle Aged; Pergolide; Pituitary Neoplasms; Pregnancy; Prolactin | 1985 |
The effect of dopamine agonist therapy on large functionless pituitary tumours.
Topics: Adenoma, Chromophobe; Adult; Bromocriptine; Dopamine; Ergolines; Female; Humans; Male; Middle Aged; Pergolide; Pituitary Neoplasms; Prolactin; Prospective Studies | 1985 |
[Hyperprolactinemia and prolactinomas. Results of surgical and drug therapy].
Topics: Adolescent; Adult; Aged; Bromocriptine; Dopamine; Drug Therapy, Combination; Ergolines; Female; Humans; Hyperprolactinemia; Lisuride; Male; Middle Aged; Paraneoplastic Endocrine Syndromes; Prolactin | 1985 |
Dopamine agonists and Parkinson's disease.
Topics: Antiparkinson Agents; Apomorphine; Brain; Bromocriptine; Ergolines; Ergot Alkaloids; Humans; Levodopa; Lisuride; Neurons; Parkinson Disease; Pergolide; Piribedil; Receptors, Dopamine | 1984 |
Biphasic influence of a 8 alpha-amino ergoline, CU 32-085, on striatal dopamine synthesis and turnover in vivo in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; alpha-Methyltyrosine; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Ergolines; Homovanillic Acid; Male; Methyltyrosines; Rats; Time Factors; Tyrosine 3-Monooxygenase | 1981 |
Therapeutic potentials of centrally acting dopamine and alpha 2-adrenoreceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Dopamine; Ergolines; Haplorhini; Humans; Neurons; Norepinephrine; Parkinson Disease; Pergolide; Quinpirole; Rats | 1983 |
Investigation of the influence of lithium upon the down-regulation of serotonin2 receptors in rat frontal cortex induced by long-term treatment with dibenzepin, an antidepressant without appreciable affinity to serotonin2 receptors.
Topics: Animals; Dibenzazepines; Ergolines; Frontal Lobe; Lithium; Male; Radioligand Assay; Rats; Receptors, Serotonin; Time Factors | 1984 |
Hypotensive action and alpha-adrenolytic properties of a new dopaminergic agonist, CU 32-085, in the rat.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Antiparkinson Agents; Blood Pressure; Bromocriptine; Clonidine; Epinephrine; Ergolines; Female; Heart Rate; Hemodynamics; Male; Methoxamine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1984 |
Therapeutic experience with the new dopamine agonist CU 32-085 in advanced Parkinson's disease.
Topics: Adult; Aged; Amantadine; Antiparkinson Agents; Bromocriptine; Carboxy-Lyases; Drug Therapy, Combination; Ergolines; Female; Humans; Levodopa; Male; Middle Aged; Parasympatholytics; Parkinson Disease | 1983 |
Mesulergine and its 1,20-N,N-bidemethylated metabolite interact directly with D1- and D2-receptors.
Topics: Adenylyl Cyclases; Animals; Antiparkinson Agents; Chemical Phenomena; Chemistry; Choline; Corpus Striatum; Ergolines; In Vitro Techniques; Male; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1983 |
Dopamine agonists in Parkinson's disease.
Topics: Bromocriptine; Dopamine; Drug Therapy, Combination; Ergolines; Ergot Alkaloids; Humans; Levodopa; Lisuride; Parkinson Disease; Pergolide; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1984 |
Dopamine agonists in the treatment of Parkinson's disease.
Topics: Blood Pressure; Bromocriptine; Disability Evaluation; Domperidone; Dopamine; Ergolines; Follow-Up Studies; Humans; Levodopa; Parkinson Disease; Pleural Effusion; Receptors, Neurotransmitter; Time Factors | 1983 |
Mesulergine, a new dopamine agonist: effects on anterior pituitary function and kinetics.
Topics: Absorption; Adult; Analysis of Variance; Biological Availability; Bromocriptine; Ergolines; Humans; Male; Pituitary Gland, Anterior; Pituitary Hormone-Releasing Hormones; Prolactin; Radioimmunoassay | 1984 |
Dopamine agonistic potency of two novel prolactin release-inhibiting ergolines.
Topics: Animals; Cells, Cultured; Dopamine; Ergolines; Male; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains | 1984 |
Mechanism of action and tolerance of mesulergine.
Topics: Adenoma; Administration, Oral; Adult; Animals; Blood Pressure; Bromocriptine; Cells, Cultured; Dopamine Antagonists; Drug Evaluation; Ergolines; Female; Humans; Hypotension; Male; Menstruation; Middle Aged; Nausea; Pituitary Neoplasms; Prolactin; Radioimmunoassay; Random Allocation; Rats | 1984 |
Mesulergine, a selective serotonin-2 ligand in the rat cortex, does not label these receptors in porcine and human cortex: evidence for species differences in brain serotonin-2 receptors.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Ergolines; Humans; In Vitro Techniques; Ketanserin; Kinetics; Ligands; Male; Piperidines; Rats; Receptors, Serotonin; Species Specificity; Swine; Tritium | 1984 |
The binding of serotonergic ligands to the porcine choroid plexus: characterization of a new type of serotonin recognition site.
Topics: Animals; Binding, Competitive; Brain; Choroid Plexus; Ergolines; Frontal Lobe; In Vitro Techniques; Kinetics; Ligands; Receptors, Serotonin; Serotonin; Swine | 1984 |
Dopaminergic properties of mesulergine (CU 32-085) and its metabolites.
Topics: Animals; Corpus Striatum; Dopamine; Ergolines; Kinetics; Male; Rats; Receptors, Dopamine | 1984 |
Low-dose CU 32-085 (mesulergine) in previously untreated Parkinson's disease.
Topics: Ergolines; Female; Humans; Male; Middle Aged; Parkinson Disease | 1984 |
Treatment of Parkinson's disease with 8-alpha-amino-ergoline, CU 32-085.
Topics: Activities of Daily Living; Adult; Aged; Antiparkinson Agents; Bromocriptine; Drug Therapy, Combination; Ergolines; Female; Humans; Hypotension, Orthostatic; Levodopa; Male; Middle Aged; Nausea; Parkinson Disease; Psychomotor Performance; Receptors, Dopamine | 1983 |
Therapeutic results with a new ergoline derivate (8-alpha-amino-ergoline, CU 32-085) in parkinsonian patients.
Topics: Aged; Antiparkinson Agents; Bromocriptine; Drug Therapy, Combination; Ergolines; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease | 1984 |
Puerperal lactation inhibition with a novel 8 alpha-aminoergoline (CU 32-085).
Topics: Adolescent; Adult; Chemical Phenomena; Chemistry; Depression, Chemical; Ergolines; Female; Humans; Lactation; Postpartum Period; Pregnancy; Prolactin | 1984 |
[3H]Mesulergine, a selective ligand for serotonin-2 receptors.
Topics: Animals; Cations; Cerebral Cortex; Ergolines; Kinetics; Lithium; Male; Rats; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1983 |
The effects of lisuride and some other dopaminergic agonists on receptor binding in human brain.
Topics: Brain; Bromocriptine; Ergolines; Humans; Kinetics; Lisuride; Receptors, Dopamine; Spiperone | 1981 |
Effects of chronic cocaine administration on the serotonergic system in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Cocaine; Ergolines; Hydroxyindoleacetic Acid; Ketanserin; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin | 1993 |
The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects of m-chlorophenylpiperazine.
Topics: Animals; Antiparkinson Agents; Binding, Competitive; Dose-Response Relationship, Drug; Ergolines; Male; Piperazines; Rats; Rats, Inbred F344; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
The 5-HT1B receptor mediates the effect of d-fenfluramine on eating caused by intra-hypothalamic injection of neuropeptide Y.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Drug Interactions; Eating; Ergolines; Fenfluramine; Hyperphagia; Hypothalamus; Injections, Intraperitoneal; Injections, Subcutaneous; Ketanserin; Male; Metergoline; Neuropeptide Y; Paraventricular Hypothalamic Nucleus; Pindolol; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Antagonists | 1995 |
Differential effects of chronic antidepressant treatment on 5-HT1C receptor binding sites in Wistar rat brain.
Topics: Animals; Brain; Clomipramine; Clorgyline; Ergolines; Imipramine; Male; Rats; Rats, Wistar; Receptors, Serotonin | 1994 |
Further evidence that the tachycardiac response to 5-hydroxytryptamine in rats is not mediated via typical 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Ergolines; Female; Heart Rate; Ketanserin; Male; Methiothepin; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin | 1994 |
Regulation of serotonin 5-HT2C receptors in the rat choroid plexus after acute clozapine treatment.
Topics: Amphetamines; Animals; Antiparkinson Agents; Autoradiography; Cerebral Cortex; Choroid Plexus; Clozapine; Ergolines; Haloperidol; Image Processing, Computer-Assisted; Injections, Subcutaneous; Male; Neostriatum; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Receptor Agonists | 1994 |
Genomic organisation and functional expression of the gene encoding the human serotonin 5-HT2C receptor.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antiparkinson Agents; Base Sequence; Binding, Competitive; Blotting, Southern; Cloning, Molecular; DNA Primers; DNA, Complementary; Ergolines; Exons; Gene Expression Regulation; Hippocampus; Humans; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Restriction Mapping; RNA, Messenger; Transfection; Type C Phospholipases | 1994 |
Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands.
Topics: 3T3 Cells; Animals; Antiparkinson Agents; Cell Membrane; Cells, Cultured; Choroid Plexus; Cloning, Molecular; DNA, Complementary; DOM 2,5-Dimethoxy-4-Methylamphetamine; Epithelium; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Lysergic Acid Diethylamide; Mianserin; Mice; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Transfection | 1994 |
Regulation of serotonin2A receptors in heterologous expression systems.
Topics: 3T3 Cells; Animals; Antiparkinson Agents; Binding, Competitive; Cell Line; Dogs; DOM 2,5-Dimethoxy-4-Methylamphetamine; Ergolines; Gene Expression Regulation; Ketanserin; Kidney; Kinetics; Mice; Pituitary Neoplasms; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1994 |
Serotonin-dopamine interaction in the rat ventral tegmental area: an electrophysiological study in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Ergolines; Male; Motor Activity; Pindolol; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Ventral Tegmental Area | 1994 |
Reciprocal binding properties of 5-hydroxytryptamine type 2C receptor agonists and inverse agonists.
Topics: 3T3 Cells; Animals; Binding, Competitive; Cell Line; DOM 2,5-Dimethoxy-4-Methylamphetamine; Ergolines; Guanine Nucleotides; Hydrolysis; Mice; Phosphatidylinositols; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
5-HT1C receptor-mediated phosphoinositide hydrolysis in the rat choroid plexus after chronic treatment with clozapine.
Topics: Amphetamines; Animals; Autoradiography; Choroid Plexus; Clozapine; Ergolines; Haloperidol; Hydrolysis; Image Processing, Computer-Assisted; In Vitro Techniques; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Second Messenger Systems; Serotonin Receptor Agonists | 1994 |
Involvement of 5-HT2C receptors in mediating the discriminative stimulus properties of m-chlorophenylpiperazine (mCPP).
Topics: Animals; Discrimination, Psychological; Dopamine Antagonists; Ergolines; Fenfluramine; Lysergic Acid Diethylamide; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Trazodone | 1994 |
Modulation of rhythmic swimming activity in post-embryonic Xenopus laevis tadpoles by 5-hydroxytryptamine acting at 5HT1a receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Cyproheptadine; Ergolines; Ketanserin; Metamorphosis, Biological; Methysergide; Motor Activity; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming; Xenopus laevis | 1994 |
Mesulergine antagonism towards the fluoxetine anti-immobility effect in the forced swimming test in mice.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ergolines; Fluoxetine; Immobilization; Male; Mice; Neurotransmitter Uptake Inhibitors; Receptors, Serotonin; Swimming | 1993 |
Analysis of the 5-HT1C receptor and the serotonin uptake site in fawn-hooded rat brain.
Topics: Animals; Binding Sites; Brain; Brain Stem; Corpus Striatum; Ergolines; Frontal Lobe; Hippocampus; Hypothalamus; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin; Serotonin | 1993 |
High and low affinity 5-HT2 and 5-HT1C binding sites: responses to neonatal 5,7-DHT lesions in rat brain.
Topics: 5,7-Dihydroxytryptamine; Analysis of Variance; Animals; Animals, Newborn; Binding Sites; Brain Neoplasms; Brain Stem; Cerebellum; Cerebral Cortex; Diencephalon; Dose-Response Relationship, Drug; Ergolines; Female; Hippocampus; Injections, Intraperitoneal; Mianserin; Pregnancy; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin; Time Factors; Tritium | 1993 |
Effect of 5,7-dihydroxytryptamine lesion on mianserin-induced conditioned place aversion and on 5-hydroxytryptamine1C receptors in the rat brain.
Topics: 5,7-Dihydroxytryptamine; Animals; Antiparkinson Agents; Autoradiography; Brain Chemistry; Carbolines; Conditioning, Operant; Ergolines; In Situ Hybridization; Male; Mianserin; Rats; Receptors, GABA-A; Receptors, Serotonin; RNA, Messenger; Transcription, Genetic | 1993 |
Modulation of 5-HT1C receptors and phosphoinositide system by ethanol consumption in rat brain and choroid plexus.
Topics: Animals; Antiparkinson Agents; Binding Sites; Brain; Cerebral Cortex; Choroid Plexus; Ergolines; Ethanol; Hippocampus; Hydrolysis; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Up-Regulation | 1993 |
Quantitative autoradiography of 5-HT1E binding sites in rodent brains: effect of lesion of serotonergic neurones.
Topics: 5,7-Dihydroxytryptamine; Animals; Autoradiography; Binding, Competitive; Brain; Brain Chemistry; Ergolines; Guinea Pigs; In Vitro Techniques; Male; Membranes; Mice; Neurons; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 1993 |
5-Carboxamidotryptamine-insensitive 5-HT1-like receptors are concentrated in guinea pig but not rat, claustrum.
Topics: Animals; Antiparkinson Agents; Autoradiography; Basal Ganglia; Brain Mapping; Ergolines; Guinea Pigs; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Species Specificity | 1993 |
5-HT1B receptors mediate potent contractile responses to 5-HT in rat caudal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Ergolines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pindolol; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Vasoconstrictor Agents | 1993 |
Autoradiographic studies of RP 62203, a potent 5-HT2 receptor antagonist. In vitro and ex vivo selectivity profile.
Topics: Animals; Antiparkinson Agents; Autoradiography; Cerebellum; Choroid Plexus; Cyclic S-Oxides; Ergolines; Guinea Pigs; In Vitro Techniques; Ketanserin; Male; Naphthalenes; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Serotonin Antagonists; Thalamus | 1993 |
A single point mutation (Phe340-->Leu340) of a conserved phenylalanine abolishes 4-[125I]iodo-(2,5-dimethoxy)phenylisopropylamine and [3H]mesulergine but not [3H]ketanserin binding to 5-hydroxytryptamine2 receptors.
Topics: Amino Acid Sequence; Amphetamines; Animals; Base Sequence; Cell Line, Transformed; Chlorocebus aethiops; Ergolines; Hydrolysis; Ketanserin; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylinositols; Point Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Identification of 5-hydroxytryptamine1D binding sites in sheep caudate nucleus membranes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Caudate Nucleus; Cell Membrane; Cerebral Cortex; Ergolines; Humans; Indoles; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Sheep; Sulfonamides; Sumatriptan; Tritium | 1993 |
Autoradiographic localization of serotonin receptor subtypes in cat visual cortex: transient regional, laminar, and columnar distributions during postnatal development.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Animals, Newborn; Antiparkinson Agents; Autoradiography; Cats; Ergolines; Granisetron; Organ Specificity; Receptors, Serotonin; Serotonin; Tritium; Visual Cortex | 1993 |
Novel regulation of 5-HT1C receptors: down-regulation induced both by 5-HT1C/2 receptor agonists and antagonists.
Topics: Analysis of Variance; Animals; Binding Sites; Down-Regulation; Ergolines; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Regression Analysis; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord | 1993 |
5-hydroxytryptamine1 recognition sites in rat brain: heterogeneity of non-5-hydroxytryptamine1A/1C binding sites revealed by quantitative receptor autoradiography.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiparkinson Agents; Autoradiography; Binding, Competitive; Brain Chemistry; Dipeptides; Ergolines; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Male; Mesencephalon; Prosencephalon; Rats; Receptors, Serotonin; Serotonin | 1993 |
Lack of cross-tolerance for hypophagia induced by DOI versus m-CPP suggests separate mediation by 5-HT2A and 5-HT2C receptors, respectively.
Topics: Amphetamines; Animals; Binding, Competitive; Drug Tolerance; Eating; Ergolines; Frontal Lobe; Injections, Intraperitoneal; Ketanserin; Male; Piperazines; Propane; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Time Factors | 1995 |
Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors: direct and indirect effects on ligand affinity mediated by the same locus.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Ergolines; Hallucinogens; Humans; Ketanserin; Kinetics; Ligands; Lysergic Acid Diethylamide; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylinositols; Point Mutation; Protein Structure, Secondary; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Transfection | 1996 |
Effects of antidepressants on intracellular Ca2+ mobilization in CHO cells transfected with the human 5-HT2C receptors.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Calcium; Calcium Channels; CHO Cells; Cricetinae; Ergolines; Humans; Intracellular Fluid; Mianserin; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Transfection | 1996 |
Functional reconstitution in situ of 5-hydroxytryptamine2c (5HT2c) receptors with alphaq and inverse agonism of 5HT2c receptor antagonists.
Topics: Animals; Binding, Competitive; Cattle; Cell Line; Decapodiformes; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Ketanserin; Mianserin; Photoreceptor Cells, Invertebrate; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Cell Surface; Receptors, Serotonin; Recombinant Proteins; Serotonin | 1996 |
Sequential onset of three 5-HT receptors during the 5-hydroxytryptaminergic differentiation of the murine 1C11 cell line.
Topics: Animals; Antiparkinson Agents; Cells, Cultured; Colforsin; Cyclic AMP; Ergolines; Gene Expression; Quinoxalines; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Time Factors | 1996 |
Chronic citalopram and fluoxetine treatments upregulate 5-HT2c receptors in the rat choroid plexus.
Topics: Amphetamines; Animals; Antiparkinson Agents; Autoradiography; Choroid Plexus; Citalopram; Ergolines; Fluoxetine; Image Processing, Computer-Assisted; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Up-Regulation | 1996 |
Serotonin2C receptors and serotonin2C receptor-mediated phosphoinositide hydrolysis in the brain of alcohol-preferring and alcohol-nonpreferring rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Brain; Brain Mapping; Choroid Plexus; Ergolines; Hydrolysis; Male; Phosphatidylinositols; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1996 |
Activities of novel aryloxyalkylimidazolines on rat 5-HT2A and 5-HT2C receptors.
Topics: 3T3 Cells; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Ergolines; Imidazoles; Lysergic Acid Diethylamide; Mice; Phosphatidylinositols; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1996 |
Effect of a dopamine agonist on the development of Leydig cell hyperplasia in Sprague-Dawley rats.
Topics: Adenoma; Animals; Antiparkinson Agents; Body Weight; Dopamine Agonists; Dose-Response Relationship, Drug; Ergolines; Extracellular Space; Hyperplasia; Leydig Cell Tumor; Leydig Cells; Male; Organ Size; Rats; Rats, Sprague-Dawley; Testicular Neoplasms | 1996 |
Characterisation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors expressed in the human neuroblastoma cell line SH-SY5Y: comparative stimulation by hallucinogenic drugs.
Topics: Adrenergic alpha-Agonists; Amphetamines; Antiparkinson Agents; Calcium; Choroid Plexus; Electrophysiology; Ergolines; Ergotamine; Frontal Lobe; Hallucinogens; Humans; Hydrolysis; Ketanserin; Lysergic Acid Diethylamide; Mescaline; Methoxydimethyltryptamines; Neuroblastoma; Phosphatidylinositols; Piperazines; Quipazine; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium; Tumor Cells, Cultured | 1996 |
Serotonin activates electrolyte transport via 5-HT2A receptor in rat colonic crypt cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Biological Transport; Calcium; Cells, Cultured; Chlorides; Colon; Egtazic Acid; Electrolytes; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Intestinal Mucosa; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin | 1997 |
Mechanism of actions of sumatriptan on coronary flow before and after endothelial dysfunction in guinea-pig isolated heart.
Topics: Animals; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Ergolines; Guinea Pigs; Heart; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Piperazines; Saponins; Serotonin Receptor Agonists; Sumatriptan; Vasoconstrictor Agents | 1997 |
Blockade of serotonin-2C receptors by mesulergine reduces ocular dominance plasticity in kitten visual cortex.
Topics: Animals; Cats; Dominance, Cerebral; Electric Stimulation; Ergolines; Functional Laterality; Microelectrodes; Neuronal Plasticity; Neurons; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Vision, Monocular; Visual Cortex; Visual Perception | 1997 |
Synthesis, affinity at 5-HT2A, 5-HT2B and 5-HT2C serotonin receptors and structure-activity relationships of a series of cyproheptadine analogues.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Choroid Plexus; Cyproheptadine; Ergolines; Gastric Fundus; In Vitro Techniques; Ketanserin; Kinetics; Male; Models, Molecular; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Swine | 1997 |
5-HT2 receptor regulation of acetylcholine release induced by dopaminergic stimulation in rat striatal slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Benzazepines; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Ergolines; Haloperidol; In Vitro Techniques; Ketanserin; Male; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Physalaemin; Potassium; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Substance P | 1997 |
Nature of 5-HT1-like receptors mediating depressor responses in vagosympathectomized rats; close resemblance to the cloned 5-ht7 receptor.
Topics: 5-Methoxytryptamine; Adrenergic beta-Agonists; Animals; Blood Pressure; Clozapine; Ergolines; Heart Rate; Isoproterenol; Lisuride; Male; Metergoline; Methiothepin; Oxadiazoles; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Sympathectomy | 1997 |
Mianserin-induced down-regulation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors stably expressed in the human neuroblastoma cell line SH-SY5Y.
Topics: Cell Membrane; DNA, Complementary; Down-Regulation; Ergolines; Humans; Ketanserin; Kinetics; Mianserin; Neuroblastoma; Phosphatidylinositols; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serotonin; Time Factors; Transfection; Tumor Cells, Cultured | 1997 |
Activating mutations of the serotonin 5-HT2C receptor.
Topics: Animals; Binding Sites; COS Cells; Ergolines; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Lysine; Methysergide; Mianserin; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylinositols; Point Mutation; Protein Conformation; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serine; Serotonin; Serotonin Antagonists; Signal Transduction; Transfection | 1997 |
Identification and characterization of a new serotonergic recognition site with high affinity for 5-carboxamidotryptamine in mammalian brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Cerebral Cortex; Ergolines; Ergotamine; Female; Guinea Pigs; Humans; Kinetics; Male; Mammals; Middle Aged; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium | 1997 |
Selective visualization of rat brain 5-HT2A receptors by autoradiography with [3H]MDL 100,907.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Cyclic S-Oxides; Ergolines; Fluorobenzenes; Guanylyl Imidodiphosphate; In Situ Hybridization; In Vitro Techniques; Ketanserin; Male; Naphthalenes; Piperidines; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists | 1997 |
Increase of cortical acetylcholine release after systemic administration of chlorophenylpiperazine in the rat: an in vivo microdialysis study.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Aporphines; Cerebral Cortex; Ergolines; Male; Microdialysis; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Innominata | 1997 |
Correlation between 5-HT7 receptor affinity and protection against sound-induced seizures in DBA/2J mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; CHO Cells; Cricetinae; Ergolines; Male; Methysergide; Mianserin; Mice; Mice, Inbred DBA; Receptors, Serotonin; Seizures; Serotonin Antagonists | 1997 |
Identification of class-determining residues in G protein-coupled receptors by sequence analysis.
Topics: Amino Acid Sequence; Binding Sites; Chlorpromazine; Ergolines; GTP-Binding Proteins; Ligands; Molecular Sequence Data; Molecular Structure; Pindolol; Propranolol; Receptors, Cell Surface; Receptors, Muscarinic; Receptors, Serotonin; Sequence Analysis; Sequence Homology, Amino Acid; Serotonin Receptor Agonists | 1997 |
Serotonin receptors in the caudal brainstem are necessary and sufficient for the anorectic effect of peripherally administered mCPP.
Topics: Animals; Appetite Depressants; Brain Stem; Decerebrate State; Dose-Response Relationship, Drug; Ergolines; Injections, Intraventricular; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists | 1998 |
5-Hydroxytryptophan-induced myoclonus in guinea pigs: mediation through 5-HT1/2 receptor subtypes.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Ergolines; Guinea Pigs; Male; Methiothepin; Myoclonus; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Substrate Specificity | 1998 |
Effect of a dopamine agonist on luteinizing hormone receptors, cyclic AMP production and steroidogenesis in rat Leydig cells.
Topics: Administration, Oral; Animals; Aromatase; Cell Separation; Chorionic Gonadotropin; Cyclic AMP; Dopamine Agonists; Ergolines; Hydroxycholesterols; Iodine Radioisotopes; Leydig Cells; Male; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, LH; Serotonin Antagonists; Signal Transduction; Testosterone | 1998 |
Selective blockade of serotonin2C/2B receptors enhances dopamine release in the rat nucleus accumbens.
Topics: Animals; Apomorphine; Cyclic S-Oxides; Dopamine; Dopamine Agonists; Ergolines; Indoles; Microdialysis; Naphthalenes; Nucleus Accumbens; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 1998 |
Effects of mesulergine treatment on diet selection, brain serotonin (5-HT) and dopamine (DA) turnover in free feeding rats.
Topics: Animals; Body Weight; Brain Chemistry; Dietary Carbohydrates; Dopamine; Dopamine Agonists; Ergolines; Food Preferences; Male; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists | 1998 |
[3H]MDL 100,907 labels 5-HT2A serotonin receptors selectively in primate brain.
Topics: Aged; Aged, 80 and over; Animals; Binding Sites; Binding, Competitive; Brain; Cyclic S-Oxides; Ergolines; Female; Fluorobenzenes; Humans; In Situ Hybridization; Ketanserin; Macaca fascicularis; Male; Naphthalenes; Piperidines; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Tritium | 1998 |
The canine external carotid vasoconstrictor 5-HT1 receptor: blockade by 5-HT1B (SB224289), but not by 5-HT1D (BRL15572) receptor antagonists.
Topics: Anesthesia; Animals; Biphenyl Compounds; Blood Pressure; Carotid Artery, External; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Ergolines; Heart Rate; Norepinephrine; Piperazines; Piperidones; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiro Compounds; Sumatriptan; Sympathectomy; Vagotomy; Vasoconstriction | 1998 |
Global increases in seizure susceptibility in mice lacking 5-HT2C receptors: a behavioral analysis.
Topics: Animals; Behavior, Animal; Brain Chemistry; Convulsants; Cornea; Disease Susceptibility; Dopamine Agonists; Electroshock; Epilepsies, Myoclonic; Epilepsy; Ergolines; Flurothyl; Kindling, Neurologic; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin | 1998 |
Structure-function studies of the eighth hydrophobic domain of a serotonin receptor.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Biological Transport; Chlorides; Ergolines; Fluorescent Antibody Technique; Gene Expression; GTP-Binding Proteins; Ligands; Molecular Sequence Data; Mutagenesis; Oocytes; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Xenopus laevis | 1999 |
Animal model of posthypoxic myoclonus: effects of serotonergic antagonists.
Topics: Acoustic Stimulation; Animals; Brain Chemistry; Disease Models, Animal; Dose-Response Relationship, Drug; Ergolines; Heart Arrest; Hypoxia; Hypoxia, Brain; Male; Methiothepin; Myoclonus; Oxadiazoles; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists | 1999 |
Pharmacological characterization of the constitutively activated state of the serotonin 5-HT2C receptor.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Cell Membrane; Ergolines; Kinetics; Lysine; Mice; Mutagenesis, Site-Directed; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serine; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 1998 |
[3H]-Mesulergine labels 5-HT7 sites in rat brain and guinea-pig ileum but not rat jejunum.
Topics: 5-Methoxytryptamine; Animals; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Ergolines; Female; Free Radical Scavengers; Guinea Pigs; Ileum; In Vitro Techniques; Jejunum; Male; Muscle Contraction; Ondansetron; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Sumatriptan; Tritium | 1999 |
High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action.
Topics: Amphetamines; Binding, Competitive; Cell Line; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrolysis; Isomerism; Ligands; Models, Biological; Phosphatidylinositols; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone | 1999 |
Systemic chlorophenylpiperazine increases acetylcholine release from rat hippocampus-implication of 5-HT2C receptors.
Topics: Acetylcholine; Animals; Aporphines; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Routes; Ergolines; Haloperidol; Hippocampus; Male; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction.
Topics: Animals; COS Cells; Ergolines; Humans; Inositol Phosphates; Kinetics; Mianserin; Mutagenesis, Site-Directed; Pargyline; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; RNA Editing; Serotonin; Serotonin Antagonists; Signal Transduction; Transfection | 1999 |
Agonist-induced GTPgamma35S binding mediated by human 5-HT(2C) receptors expressed in human embryonic kidney 293 cells.
Topics: Cyclic AMP; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol 1,4,5-Trisphosphate; Kidney; Pertussis Toxin; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Virulence Factors, Bordetella | 1999 |
Distribution and characterization of [3H]mesulergine binding in human brain postmortem.
Topics: Adult; Aged; Aged, 80 and over; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Choroid Plexus; Dopamine Antagonists; Ergolines; Female; Humans; Male; Middle Aged; Postmortem Changes; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Substrate Specificity; Tissue Distribution; Tritium | 1999 |
Characterisation of a 5-HT(7) binding site in mouse ileum.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Ergolines; Female; Ileum; Male; Mice; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 2000 |
Subthalamic nucleus microinjections of 5-HT2 receptor antagonists suppress stereotypy in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Clozapine; Ergolines; Fluorobenzenes; Male; Mastication; Microinjections; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Stereotypic Movement Disorder; Subthalamic Nucleus | 2000 |
Auditory responses from the frontal cortex in the mustached bat, Pteronotus parnellii.
Topics: Animals; Apomorphine; Behavior, Animal; Clozapine; Ergolines; Fluorobenzenes; Male; Mastication; Microinjections; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Stereotypic Movement Disorder; Subthalamic Nucleus | 2000 |
An innovative method for rapid characterisation of phospholipase C activity: SB242,084 competitively antagonises 5-HT2C receptor-mediated [3H]phosphatidylinositol depletion.
Topics: Aminopyridines; Animals; CHO Cells; Cricetinae; Ergolines; Humans; Indoles; Phosphatidylinositols; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Type C Phospholipases | 2000 |
Antagonist binding at 5-HT(2A) and 5-HT(2C) receptors in the rabbit: high correlation with the profile for the human receptors.
Topics: Animals; Cerebral Cortex; Ergolines; Female; Fluorobenzenes; Humans; Male; Piperidines; Rabbits; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists | 2000 |
In vivo analysis of adrenergic and serotoninergic constrictions of the rabbit saphenous vein.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Benzazepines; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Ergolines; Imidazoles; Indoles; Injections, Intravenous; Isoindoles; Oxadiazoles; Peripheral Nervous System; Phenylephrine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Serotonin; Saphenous Vein; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Sumatriptan; Tetrahydronaphthalenes; Time Factors; Ultrasonography, Doppler; Vasoconstrictor Agents | 2000 |
5-HT2C receptor binding is increased in the substantia nigra pars reticulata in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Autoradiography; Binding Sites; Brain; Dopamine Agonists; Dyskinesia, Drug-Induced; Ergolines; Female; Humans; Male; Parkinson Disease; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Substantia Nigra | 2000 |
Conserved helix 7 tyrosine functions as an activation relay in the serotonin 5HT(2C) receptor.
Topics: Amino Acid Motifs; Amphetamines; Binding, Competitive; Cell Line; Conserved Sequence; Ergolines; Humans; Indoles; Inositol Phosphates; Ligands; Mianserin; Mutation; Protein Structure, Secondary; Pyridines; Quipazine; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection; Tyrosine | 2000 |
No involvement of 5-HT(7) or 5-HT(1D) receptors in the (R)-8-OH-DPAT-induced depression of the monosynaptic reflex in spinalized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clozapine; Decerebrate State; Dose-Response Relationship, Drug; Ergolines; Indoles; Male; Methiothepin; Oxadiazoles; Phenols; Piperazines; Pyridines; Rats; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors | 2001 |
RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity.
Topics: Amphetamines; Animals; Arachidonic Acid; Binding, Competitive; Bufotenin; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Ergolines; Inositol Phosphates; Lysergic Acid Diethylamide; Piperazines; Protein Isoforms; Quipazine; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; RNA Editing; Serotonin; Serotonin Receptor Agonists; Tritium | 2001 |
Regional distribution and cellular localization of 5-HT2C receptor mRNA in monkey brain: comparison with [3H]mesulergine binding sites and choline acetyltransferase mRNA.
Topics: Animals; Binding Sites; Brain; Choline O-Acetyltransferase; Ergolines; Female; Macaca fascicularis; Macaca mulatta; Male; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists | 2001 |
Different regulation of rat 5-HT(2A) and rat 5-HT(2C) receptors in NIH 3T3 cells upon exposure to 5-HT and pipamperone.
Topics: 3T3 Cells; Animals; Benzamides; Binding Sites; Binding, Competitive; Butyrophenones; Dose-Response Relationship, Drug; Ergolines; Gene Expression; Inositol Phosphates; Iodine Radioisotopes; Membranes; Mice; Piperidines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Agents; Serotonin Antagonists; Time Factors; Tritium | 2001 |
Allosteric modulation of the human 5-HT(7A) receptor by lipidic amphipathic compounds.
Topics: Allosteric Regulation; Cells, Cultured; Ergolines; HeLa Cells; Humans; Oleic Acid; Oleic Acids; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium | 2001 |
5-HT receptor subtypes involved in the spinal antinociceptive effect of acetaminophen in rats.
Topics: Acetaminophen; Analgesics; Animals; Ergolines; Granisetron; Injections, Spinal; Ketanserin; Male; Pain Threshold; Penbutolol; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Time Factors; Vocalization, Animal | 2001 |
Up-regulation of 5-HT2B receptor density and receptor-mediated glycogenolysis in mouse astrocytes by long-term fluoxetine administration.
Topics: Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Drug Administration Schedule; Ergolines; Fluoxetine; Glycogen; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Protein Isoforms; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Up-Regulation | 2002 |
Autoradiographic distribution of 5-HT7 receptors in the human brain using [3H]mesulergine: comparison to other mammalian species.
Topics: 5-Methoxytryptamine; Amphetamines; Animals; Autoradiography; Brain; Cerebral Cortex; Corpus Striatum; Ergolines; Guinea Pigs; Humans; Male; Mammals; Radioligand Assay; Radionuclide Imaging; Rats; Rats, Wistar; Receptors, Serotonin; Tritium | 2004 |
Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout mice.
Topics: Animals; Binding Sites; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Eating; Ergolines; Fenfluramine; Genotype; Injections, Intraperitoneal; Injections, Subcutaneous; Isomerism; Mianserin; Mice; Mice, Knockout; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Satiation; Satiety Response; Serotonin 5-HT2 Receptor Agonists; Species Specificity; Spiperone; Spiro Compounds; Time Factors; Tritium; United Kingdom | 2004 |
Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors.
Topics: Animals; Binding, Competitive; CHO Cells; Clozapine; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Ergolines; Humans; Loxapine; Methiothepin; Phenols; Pimozide; Pindolol; Piperidines; Plasmids; Pyrrolidines; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tosyl Compounds; Transfection | 2004 |
Regulation of serotonin 5-HT2C receptors by chronic ligand exposure.
Topics: Algorithms; Analysis of Variance; Animals; Binding, Competitive; Cell Membrane; Chlorpromazine; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Ergolines; Humans; Indoles; Indophenol; Inositol Phosphates; Kinetics; Ligands; Lisuride; Mianserin; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium; Tryptamines | 2004 |
Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Ergolines; Heterotrimeric GTP-Binding Proteins; Insecta; Protein Binding; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Receptors, G-Protein-Coupled; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists | 2004 |
Serotonin 5-HT2C receptor-mediated phosphoinositide hydrolysis in rat choroid plexus after fluoxetine and citalopram treatments.
Topics: Amphetamines; Animals; Choroid Plexus; Citalopram; Dose-Response Relationship, Drug; Ergolines; Fluoxetine; Hydrolysis; Inositol Phosphates; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Second Messenger Systems; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2005 |
Decreased 5-HT2C receptor binding in the cerebral cortex and brain stem during pancreatic regeneration in rats.
Topics: Animals; Binding, Competitive; Brain Stem; Cerebral Cortex; Ergolines; Pancreas; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Regeneration; Serotonin; Serotonin Antagonists | 2005 |
Effects of mu-CPP and mesulergine on dietary choices in deprived rats: possible mechanisms of their action.
Topics: Animals; Apomorphine; Behavior, Animal; Choice Behavior; Diet; Dopamine Agonists; Dose-Response Relationship, Drug; Eating; Ergolines; Food Deprivation; Male; Piperazines; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists | 2006 |
Hypothalamic 5-HT functional regulation through 5-HT1A and 5-HT2C receptors during pancreatic regeneration.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Down-Regulation; Ergolines; Gene Expression Regulation, Developmental; Hypothalamus; Male; Pancreas; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Regeneration; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2006 |
Development of homogeneous high-affinity agonist binding assays for 5-HT2 receptor subtypes.
Topics: Amphetamines; Binding, Competitive; Calcium Signaling; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ergolines; Humans; Ketanserin; Lysergic Acid Diethylamide; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 2005 |
Combined treatment with citalopram and buspirone: effects on serotonin 5-HT2A and 5-HT2C receptors in the rat brain.
Topics: Amphetamines; Animals; Anti-Anxiety Agents; Antidepressive Agents; Autoradiography; Brain Chemistry; Buspirone; Cerebral Cortex; Choroid Plexus; Citalopram; Ergolines; Hydrolysis; Image Processing, Computer-Assisted; Ketanserin; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists | 2006 |
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor.
Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Cell Line; Cell Membrane; Clozapine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ergolines; Gene Expression; Humans; Isoproterenol; Isoquinolines; Methiothepin; Multivariate Analysis; Phenols; Protein Isoforms; Protein Kinase Inhibitors; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors; Tritium | 2006 |
Fatty acids differentially affect serotonin receptor and transporter binding in the rat brain.
Topics: Analysis of Variance; Animals; Brain; Ergolines; Fatty Acids; Ketanserin; Male; Paroxetine; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 2006 |
Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists--Increasing selectivity over hERG.
Topics: Biphenyl Compounds; ERG1 Potassium Channel; Ergolines; Ether-A-Go-Go Potassium Channels; Humans; Indicators and Reagents; Mianserin; Naphthalenes; Potassium Channel Blockers; Receptor, Serotonin, 5-HT2C; Receptors, Somatostatin; Serotonin Antagonists; Structure-Activity Relationship | 2007 |
Diabetes-induced changes in 5-hydroxytryptamine modulation of vagally-induced bradycardia in rat heart.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Biphenyl Compounds; Blood Glucose; Bradycardia; Cholinergic Agents; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Ergolines; Heart; Heart Rate; Injections, Intravenous; Male; Methiothepin; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vagus Nerve | 2007 |
Upregulation of 5-HT2C receptors in hippocampus of pilocarpine-induced epileptic rats: antagonism by Bacopa monnieri.
Topics: Animals; Anticonvulsants; Bacopa; Carbamazepine; Disease Models, Animal; Epilepsy; Ergolines; Hippocampus; Inositol 1,4,5-Trisphosphate; Male; Pilocarpine; Plant Preparations; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Statistics, Nonparametric; Swimming; Tritium; Up-Regulation | 2009 |
Reversal of haloperidol-induced motor deficits by mianserin and mesulergine in rats.
Topics: Animals; Antipsychotic Agents; Catalepsy; Dopamine Agonists; Dyskinesia, Drug-Induced; Ergolines; Haloperidol; Male; Mianserin; Motor Activity; Parkinson Disease, Secondary; Psychomotor Performance; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors | 2011 |
Differences between human wild-type and C23S variant 5-HT2C receptors in inverse agonist-induced resensitization.
Topics: Adult; Aequorin; Base Sequence; Calcium; DNA, Complementary; Drug Inverse Agonism; Ergolines; HEK293 Cells; Humans; Indoles; Luminescent Measurements; Protein Binding; Pyridines; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Antagonists; Time Factors | 2011 |
Hippocampal serotonin depletion facilitates the enhancement of prepulse inhibition by risperidone: possible role of 5-HT(2C) receptors in the dorsal hippocampus.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Ergolines; Hippocampus; Male; Nerve Tissue Proteins; Neural Inhibition; Neurons; Organ Specificity; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Reflex, Startle; Risperidone; Schizophrenia; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2011 |
Influence of serotonergic 5-HT2C receptor antagonist mesulergine in the reversal of memory deficits induced by mCPP.
Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Ergolines; Male; Maze Learning; Memory Disorders; Memory, Long-Term; Memory, Short-Term; Piperazines; Random Allocation; Rats; Rats, Wistar; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2012 |
Synthesis and SAR study of 4-arylpiperidines and 4-aryl-1,2,3,6-tetrahydropyridines as 5-HT₂C agonists.
Topics: Animals; Appetite Depressants; Calcium; Ergolines; Humans; Kinetics; Piperidines; Protein Binding; Pyridines; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship | 2012 |
The N-terminal region of the human 5-HT₂C receptor has as a cleavable signal peptide.
Topics: Amino Acid Sequence; Animals; Cell Membrane; Chlorocebus aethiops; COS Cells; Ergolines; Gene Expression Regulation; Humans; Molecular Sequence Data; Polymorphism, Single Nucleotide; Protein Sorting Signals; Protein Structure, Secondary; Proteolysis; Receptor, Serotonin, 5-HT2C; Transfection | 2012 |
Molecular and behavioral pharmacology of two novel orally-active 5HT2 modulators: potential utility as antipsychotic medications.
Topics: Amphetamines; Animals; Antipsychotic Agents; Cell Line, Transformed; Dose-Response Relationship, Drug; Ergolines; Food Preferences; Glycolates; Head Movements; Humans; Ketanserin; Mice; Mice, Inbred C57BL; Motor Activity; Protein Binding; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium | 2013 |
Multiple conformations of 5-HT2A and 5-HT 2C receptors in rat brain: an autoradiographic study with [125I](±)DOI.
Topics: Aminopyridines; Animals; Autoradiography; Brain; Ergolines; Indoles; Ketanserin; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin | 2013 |
Neurotensin-like peptides as potential antipsychotics: modulation of the serotonin system.
Topics: Animals; Antipsychotic Agents; Cell Membrane; Ergolines; Frontal Lobe; Ketanserin; Male; Mice; Neurotensin; Oligopeptides; Piperazines; Platelet Aggregation; Radioligand Assay; Rats; Serotonin; Serotonin Antagonists; Statistics, Nonparametric | 2014 |
The atypical antipsychotics clozapine and olanzapine promote down-regulation and display functional selectivity at human 5-HT7 receptors.
Topics: Antipsychotic Agents; Arrestins; Benzodiazepines; beta-Arrestins; Cells, Cultured; Chloroquine; Clozapine; Down-Regulation; Drug Inverse Agonism; Ergolines; HEK293 Cells; Humans; Ligands; Lysosomes; Olanzapine; Phenols; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Sulfonamides | 2015 |
Allosteric Inhibition of Serotonin 5-HT
Topics: Allosteric Regulation; Cell Death; Cell Survival; Cyclic AMP; Ergolines; HEK293 Cells; Humans; Ions; Kinetics; Ligands; Phenols; Receptors, Serotonin; Sulfonamides; Zinc | 2018 |