mesotrione has been researched along with nitisinone in 4 studies
| Studies (mesotrione) | Trials (mesotrione) | Recent Studies (post-2010) (mesotrione) | Studies (nitisinone) | Trials (nitisinone) | Recent Studies (post-2010) (nitisinone) |
|---|---|---|---|---|---|
| 130 | 2 | 101 | 242 | 12 | 150 |
| Protein | Taxonomy | mesotrione (IC50) | nitisinone (IC50) |
|---|---|---|---|
| 4-hydroxyphenylpyruvate dioxygenase | Rattus norvegicus (Norway rat) | 0.04 | |
| 4-hydroxyphenylpyruvate dioxygenase | Sus scrofa (pig) | 0.04 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernardini, G; Braconi, D; Manetti, F; Petricci, E; Santucci, A | 1 |
| Eksborg, S; Hall, MG; Lumholtz, B; Provan, WM; Wilks, MF | 1 |
| Aldámiz-EchevarrÃa, L; Andrade, F; Lage, S; Prieto, JA | 1 |
| Dong, JQ; Hao, GF; Lin, HY; Wang, DW; Wang, YX; Wu, JW; Yang, GF; Yang, JF; Yang, WC; Zhan, CG | 1 |
1 review(s) available for mesotrione and nitisinone
| Article | Year |
|---|---|
4-Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Animals; Drug Discovery; Enzyme Inhibitors; Herbicides; Humans; Models, Molecular; Plants; Small Molecule Libraries; Tyrosinemias; Weed Control | 2017 |
1 trial(s) available for mesotrione and nitisinone
| Article | Year |
|---|---|
Pharmacokinetics and pharmacodynamics of NTBC (2-(2-nitro-4-fluoromethylbenzoyl)-1,3-cyclohexanedione) and mesotrione, inhibitors of 4-hydroxyphenyl pyruvate dioxygenase (HPPD) following a single dose to healthy male volunteers.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Administration, Oral; Area Under Curve; Chemistry, Pharmaceutical; Cyclohexanones; Enzyme Inhibitors; Half-Life; Humans; Male; Nitrobenzoates; Therapeutic Equivalency; Tyrosine; Tyrosinemias | 2001 |
2 other study(ies) available for mesotrione and nitisinone
| Article | Year |
|---|---|
Comparison of plasma and dry blood spots as samples for the determination of nitisinone (NTBC) by high-performance liquid chromatography-tandem mass spectrometry. Study of the stability of the samples at different temperatures.
Topics: Adolescent; Analysis of Variance; Blood Specimen Collection; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cyclohexanones; Drug Stability; Female; Humans; Male; Nitrobenzoates; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Temperature; Time Factors; Tyrosinemias | 2011 |
Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Amino Acid Sequence; Computer Simulation; Crystallography, X-Ray; Cyclohexanones; Enzyme Inhibitors; Herbicides; Kinetics; Mesylates; Molecular Structure; Nitrobenzoates; Sequence Homology, Amino Acid | 2019 |