mesotocin and pressinoic-acid

mesotocin has been researched along with pressinoic-acid* in 1 studies

Other Studies

1 other study(ies) available for mesotocin and pressinoic-acid

Article	Year
Plasma levels of immunoreactive mesotocin and vasotocin during oviposition in chickens: relationship to oxytocic action of the peptides in vitro and peptide interaction with myometrial membrane binding sites. General and comparative endocrinology, 1988, Volume: 70, Issue:1 Plasma concentrations of immunoreactive vasotocin (AVT) and mesotocin (MT) were measured periodically before and subsequent to spontaneous oviposition in conscious chickens. The concentrations of AVT and MT approximately an hour prior to oviposition were 5.2 +/- 1.1 microU/ml and 14.7 +/- 5.1 pg/ml, respectively. Plasma AVT levels increased abruptly at oviposition (25.1 +/- 3.3 microU/ml) and decreased to 5.0 +/- 0.6 microU/ml within 30 min postoviposition. Significant changes in MT were not observed. The data indicate that AVT is selectively released during oviposition. The uterus was removed immediately after oviposition and the oxytocic potencies of several peptides were tested on muscle strips in vitro. The order of oxytocic potencies was AVT greater than or equal to arginine vasopressin (AVP) much greater than MT = pressinoic acid. Partially purified membranes were prepared from separate portions of the uteri used in the oxytocic assay. [3H]arginine8 vasopressin, [3H]AVP, bound to membranes saturably (Bmax = 17 fmol/mg protein) and with high affinity (Kd = 0.7 nM). The rank order of potency of the peptides in displacing [3H]AVP from the binding sites was the same as in the oxytocic assay which suggests that the [3H]AVP binding sites in uterine membranes represent physiological receptors that interact with AVT during oviposition. Topics: Animals; Arginine Vasopressin; Binding, Competitive; Biological Assay; Cell Membrane; Chickens; Female; Kinetics; Myometrium; Oviposition; Oxytocin; Uterine Contraction; Vasopressins; Vasotocin	1988

Article

Year

Plasma levels of immunoreactive mesotocin and vasotocin during oviposition in chickens: relationship to oxytocic action of the peptides in vitro and peptide interaction with myometrial membrane binding sites.

General and comparative endocrinology, 1988, Volume: 70, Issue:1

Plasma concentrations of immunoreactive vasotocin (AVT) and mesotocin (MT) were measured periodically before and subsequent to spontaneous oviposition in conscious chickens. The concentrations of AVT and MT approximately an hour prior to oviposition were 5.2 +/- 1.1 microU/ml and 14.7 +/- 5.1 pg/ml, respectively. Plasma AVT levels increased abruptly at oviposition (25.1 +/- 3.3 microU/ml) and decreased to 5.0 +/- 0.6 microU/ml within 30 min postoviposition. Significant changes in MT were not observed. The data indicate that AVT is selectively released during oviposition. The uterus was removed immediately after oviposition and the oxytocic potencies of several peptides were tested on muscle strips in vitro. The order of oxytocic potencies was AVT greater than or equal to arginine vasopressin (AVP) much greater than MT = pressinoic acid. Partially purified membranes were prepared from separate portions of the uteri used in the oxytocic assay. [3H]arginine8 vasopressin, [3H]AVP, bound to membranes saturably (Bmax = 17 fmol/mg protein) and with high affinity (Kd = 0.7 nM). The rank order of potency of the peptides in displacing [3H]AVP from the binding sites was the same as in the oxytocic assay which suggests that the [3H]AVP binding sites in uterine membranes represent physiological receptors that interact with AVT during oviposition.

Topics: Animals; Arginine Vasopressin; Binding, Competitive; Biological Assay; Cell Membrane; Chickens; Female; Kinetics; Myometrium; Oviposition; Oxytocin; Uterine Contraction; Vasopressins; Vasotocin

1988