mesoridazine and thioridazine

mesoridazine has been researched along with thioridazine in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199047 (64.38)18.7374
1990's7 (9.59)18.2507
2000's14 (19.18)29.6817
2010's5 (6.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hulshoff, A; Perrin, JH1
Keserü, GM1
Nagashima, R; Nishikawa, T; Tobita, M1
Jia, L; Sun, H1
Ahman, M; Holmén, AG; Wan, H1
Giordanetto, F; Leach, AG; Zachariae, U1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Sen, S; Sinha, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chou, TC; Fowler, NO; Hanenson, IB; Holmes, JC; McCall, D1
Blum, A; Forrest, IS; Green, DE; Loeffler, KO; Serra, MT2
Bowers, PA; Cole, JO; Gardos, G; Tecce, JJ1
Dinovo, EC; Gottschalk, LA; Nandi, BR1
Donlon, PT; Tupin, JP1
Dinovo, EC; Geddes, PG; Gottschalk, LA; Nandi, BR1
Swett, C1
Frei, RW; Lindner, W; Santi, W1
Craig, JC; Gruenke, LD1
Belpaire, FM; Vandeheeren, FA1
Belpaire, FM; Bogaert, MG; Vanderheeren, FA1
Baumann, P; Eap, CB; Koeb, L; Souche, A1
Berens, K; Cleary, J; Poling, A; Thompson, T1
Hammarlund-Udenaes, M; Hedberg, A; Lidén, A; Movin, G; Nordin, C; Ring, H; Sjöqvist, F; von Bahr, C1
Beijersbergen van Henegouwen, GM; Panday, IR; Schoonderwoerd, SA1
Chakraborty, BS; Choc, MG; Hawes, EM; Hubbard, JW; Korchinski, ED; McKay, G; Midha, KK; Robinson, WT2
Cubeddu, LX; Mailman, RB; Niedzwiecki, DM3
Millichamp, CJ; Singh, NN1
Gerbino, L; Katz, IR; Kay, SR; Opler, LA; Vital-Herne, J1
Richelson, E1
Brown, WA; Rao, ML; Wagner, R1
Chakraborty, BS; Hawes, EM; Midha, KK1
Chakraborty, BS; Hawes, EM; Jaworski, TJ; Midha, KK; Sardessai, MS1
Greendyke, RM; Kanter, DR1
Crammer, JL; Papadopoulos, AS1
Siebel, G; Vertrees, JE1
Gottschalk, LA1
Cowan, DA; Crammer, JL; Papadopoulos, AS1
Dillenkoffer, RL; Gallant, DM; Phillips, JH1
Berner, W; Konzett, H; Lochs, H1
Crane, GE; Smeets, RA1
Biener, R; Dinovo, EC; Gottschalk, LA; Noble, EP1
Auvinen, J; Linnolia, M; Vaisanen, K; Viukari, M1
Jeste, DV; Linnoila, M; Wagner, RL; Wyatt, RJ1
Nwokeafor, V; Shvartsburd, A; Smith, RC1
Lewis, MH; Mailman, RB; Mobilio, JN; Rissmiller, DJ1
Allen, P; Baumgartner, R; Johnson, R; Ravichandran, GK; Schoolar, JC; Shvartsburd, A; Smith, RC1
Dinovo, EC; Gottschalk, LA; Pollak, H1
Auvinen, J; Linnoila, M; Vaisanen, K; Viukari, M1
Breuning, SE; Davidson, NA1
Furman, WB; Juenge, EC; Wells, CE1
Räisänen, P; Rimón, R; Väisänen, K; Viukari, M1
Breuning, SE; Ferguson, DG; O'Neill, MJ1
Chand, TG; Crammer, JL; Lader, S; Papadopoulos, AS1
Baumann, P; Eap, CB; Guentert, TW; Koeb, L; Powell, K; Schãublin-Loidl, M; Stabl, M1
Chu, KW; Damani, LA; Hawes, EM; Lin, G; Midha, KK1
Agundez, JA; Benítez, J; Berecz, R; Carrillo, JA; Duran, M; Herraiz, AG; Llerena, A; Ramos, SI1
Benítez, J; Berecz, R; de la Rubia, A; Llerena, A; Norberto, MJ1
Dallaire, S1
Collier, PS; Millership, JS; Morrow, RJ1
Berecz, R; de la Rubia, A; Dorado, P; Llerena, A; Peñas-Lledó, EM1
McKay, GA; Salih, IS; Thanacoody, RH; Thomas, SH1
Daly, AK; Ferrier, IN; Reilly, JG; Thanacoody, RH; Thomas, SH1
Bonato, PS; Borges, KB; De Souza Borges, W; Pupo, MT1
Charalampous, KD; Estevez, V; Johnson, PC1
de la Rubia, A; Dorado, P; LLerena, A; Peñas-LLedó, EM1
Bertucci, C; Bonato, PS; Borges, KB; Guimarães, LF; Mazzeo, G; Okano, LT; Rosini, C1
Kümmerer, K; Leder, C; Menz, J; Wilde, ML1

Reviews

3 review(s) available for mesoridazine and thioridazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacological treatment of self-injurious behavior in mentally retarded persons.
    Journal of autism and developmental disorders, 1985, Volume: 15, Issue:3

    Topics: Adolescent; Anti-Anxiety Agents; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Double-Blind Method; Female; Haloperidol; Humans; Intellectual Disability; Lithium; Lithium Carbonate; Male; Mesoridazine; Methylphenidate; Phenothiazines; Psychotropic Drugs; Reserpine; Self Mutilation; Thioridazine

1985
The pharmacokinetics of some psychoactive drugs and relationships to clinical response.
    Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:5

    Topics: Humans; Kinetics; Mental Disorders; Mesoridazine; Psychotropic Drugs; Research; Schizophrenia; Thioridazine

1985

Trials

9 trial(s) available for mesoridazine and thioridazine

ArticleYear
Plasma levels of thioridazine and metabolites are influenced by the debrisoquin hydroxylation phenotype.
    Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:3

    Topics: Adult; Antidepressive Agents; Debrisoquin; Humans; Hydroxylation; Male; Mesoridazine; Phenothiazines; Phenotype; Thioridazine

1991
Mesoridazine and thioridazine: clinical effects and blood levels in refractory schizophrenics.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:7

    Topics: Adult; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Female; Hospitalization; Humans; Kinetics; Male; Mesoridazine; Psychiatric Status Rating Scales; Receptors, Dopamine; Schizophrenia; Schizophrenic Psychology; Thioridazine

1986
Electrocardiographic evaluation of mesoridazine (Serentil).
    Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:2

    Topics: Adult; Cardiovascular System; Clinical Trials as Topic; Electrocardiography; Female; Humans; Male; Mesoridazine; Middle Aged; Phenothiazines; Schizophrenia; Thioridazine; Time Factors; Tranquilizing Agents

1972
Emotionally induced cardiovascular changes in man as a means for the investigation of tranquillizing drugs.
    Psychopharmacologia, 1973, Volume: 30, Issue:1

    Topics: Adult; Blood Pressure; Forearm; Heart Rate; Hemodynamics; Humans; Male; Mesoridazine; Placebos; Regional Blood Flow; Stress, Psychological; Task Performance and Analysis; Thioridazine; Time Factors

1973
Red blood cell and plasma levels of thioridazine and mesoridazine in schizophrenic patients.
    Psychopharmacology, 1984, Volume: 82, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aging; Chromatography, Gas; Dose-Response Relationship, Drug; Erythrocytes; Half-Life; Humans; Mesoridazine; Middle Aged; Schizophrenia; Spectrometry, Fluorescence; Thioridazine

1984
Haloperidol, thioridazine and placebo in mentally subnormal patients-serum levels and clinical effects.
    Acta psychiatrica Scandinavica, 1981, Volume: 63, Issue:3

    Topics: Adolescent; Adult; Clinical Trials as Topic; Female; Haloperidol; Humans; Intellectual Disability; Male; Mesoridazine; Middle Aged; Placebos; Psychomotor Agitation; Random Allocation; Thioridazine

1981
Plasma levels of the enantiomers of thioridazine, thioridazine 2-sulfoxide, thioridazine 2-sulfone, and thioridazine 5-sulfoxide in poor and extensive metabolizers of dextromethorphan and mephenytoin.
    Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Depressive Disorder; Dextromethorphan; Double-Blind Method; Female; Humans; Male; Mephenytoin; Mesoridazine; Middle Aged; Mixed Function Oxygenases; Phenothiazines; Stereoisomerism; Thioridazine

1996
No effect of the CYP1A2*1F genotype on thioridazine, mesoridazine, sulforidazine plasma concentrations in psychiatric patients.
    European journal of clinical pharmacology, 2007, Volume: 63, Issue:5

    Topics: Alleles; Antipsychotic Agents; Cytochrome P-450 CYP1A2; Debrisoquin; Dose-Response Relationship, Drug; Genotype; Humans; Mental Disorders; Mesoridazine; Phenothiazines; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Smoking; Thioridazine

2007
Comparison of the effects of thioridazine and mesoridazine on the QT interval in healthy adults after single oral doses.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:5

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Area Under Curve; Cross-Over Studies; Dopamine Antagonists; Double-Blind Method; Electrocardiography; Female; Heart Conduction System; Humans; Long QT Syndrome; Male; Mesoridazine; Middle Aged; Reference Values; Thioridazine

2007

Other Studies

61 other study(ies) available for mesoridazine and thioridazine

ArticleYear
Quantitative correlations between albumin binding constants and chromatographic Rm values of phenothiazine derivatives.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:3

    Topics: Binding Sites; Chromatography, Thin Layer; Circular Dichroism; Kinetics; Mathematics; Phenothiazines; Protein Binding; Serum Albumin, Bovine; Solubility; Sulfathiazoles

1977
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
    Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14

    Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs.
    The American journal of cardiology, 1976, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; Chlorpromazine; Digitalis Glycosides; Diuretics; Electrocardiography; Female; Heart Failure; Humans; Hypotension; Lidocaine; Male; Mesoridazine; Middle Aged; Phenothiazines; Psychotropic Drugs; Thioridazine

1976
Studies on thioridazine and mesoridazine metabolism. II. In vivo metabolism of tritiated drugs in rhesus monkeys.
    Communications in psychopharmacology, 1979, Volume: 3, Issue:5

    Topics: Animals; Blood Proteins; Feces; Female; Haplorhini; Macaca mulatta; Male; Mesoridazine; Thioridazine; Time Factors

1979
A CNV typology of chronic schizophrenics and response to drug treatment.
    Psychopharmacology bulletin, 1979, Volume: 15, Issue:1

    Topics: Adult; Contingent Negative Variation; Electrophysiology; Female; Humans; Male; Mesoridazine; Middle Aged; Schizophrenia; Thioridazine

1979
Studies on thioridazine and mesoridazine metabolism. I. Protein binding.
    Communications in psychopharmacology, 1979, Volume: 3, Issue:5

    Topics: Blood Proteins; Humans; Mesoridazine; Protein Binding; Renal Dialysis; Thioridazine

1979
The assay of plasma concentration of thioridazine and its metabolites as a function of time.
    Communications in psychopharmacology, 1978, Volume: 2, Issue:6

    Topics: Biotransformation; Chromatography, Gas; Humans; Mesoridazine; Spectrometry, Fluorescence; Thioridazine; Time Factors

1978
Successful suicides with thioridazine and mesoridazine: a result of probable cardiotoxicity.
    Archives of general psychiatry, 1977, Volume: 34, Issue:8

    Topics: Adult; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Arrest; Heart Block; Heart Conduction System; Humans; Male; Mesoridazine; Middle Aged; Suicide; Thioridazine

1977
GLC analysis of thioridazine, mesoridazine, and their metabolites.
    Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:5

    Topics: Chromatography, Gas; Fluorometry; Humans; Mesoridazine; Methods; Sulfones; Sulfoxides; Thioridazine; Time Factors

1976
Drug-induced dystonia.
    The American journal of psychiatry, 1975, Volume: 132, Issue:5

    Topics: Adjustment Disorders; Adult; Basal Ganglia Diseases; Chlorpromazine; Chlorprothixene; Female; Fluphenazine; Haloperidol; Humans; Male; Mental Disorders; Mesoridazine; Middle Aged; Perphenazine; Psychotic Disorders; Psychotropic Drugs; Schizophrenia; Thioridazine; Thiothixene; Trifluoperazine

1975
Serentil for chronic brain syndrome.
    The Medical letter on drugs and therapeutics, 1975, Aug-01, Volume: 17, Issue:16

    Topics: Aged; Dementia; Drug Evaluation; Humans; Mesoridazine; Neurocognitive Disorders; Thioridazine

1975
Combined ultraviolet-fluorescence detection in high-pressure liquid chromatography of pharmaceuticals.
    Journal of chromatography, 1975, Sep-03, Volume: 111, Issue:2

    Topics: Chromatography, High Pressure Liquid; Mesoridazine; Methods; Oxidation-Reduction; Phenothiazines; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thioridazine

1975
Identification of a metabolite of thioridazine and mesoridazine from human plasma.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 10, Issue:2

    Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Thin Layer; Humans; Isomerism; Mass Spectrometry; Mesoridazine; Sulfones; Thioridazine

1975
Albumin binding of thioridazine and some of its metabolites.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 214, Issue:1

    Topics: Animals; Cattle; Dialysis; Mesoridazine; Molecular Conformation; Molecular Weight; Protein Binding; Serum Albumin, Bovine; Thioridazine

1975
Binding of thioridazine and some of its metabolites to human serum protein and human albumin.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:12

    Topics: Adult; Animals; Blood Proteins; Humans; Male; Mesoridazine; Protein Binding; Serum Albumin; Thioridazine

1975
Light-induced racemization: artifacts in the analysis of the diastereoisomeric pairs of thioridazine 5-sulfoxide in the plasma and urine of patients treated with thioridazine.
    Therapeutic drug monitoring, 1991, Volume: 13, Issue:4

    Topics: Adult; Antidepressive Agents; Chromatography, High Pressure Liquid; Female; Humans; Light; Male; Mental Disorders; Mesoridazine; Middle Aged; Phenothiazines; Stereoisomerism; Thioridazine

1991
Neuroleptics and learning: effects of haloperidol, molindone, mesoridazine and thioridazine on the behavior of pigeons under a repeated acquisition procedure.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Chlorpromazine; Columbidae; Dose-Response Relationship, Drug; Haloperidol; Learning; Male; Mesoridazine; Molindone; Thioridazine

1990
UVA-induced genetic effects of thioridazine, mesoridazine and sulforidazine: an in vitro study.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 1990, Volume: 45, Issue:6

    Topics: Antidepressive Agents; DNA; DNA Repair; Escherichia coli; Mesoridazine; Peroxidases; Phenothiazines; Thioridazine; Ultraviolet Rays

1990
Single dose kinetics of thioridazine and its two psychoactive metabolites in healthy humans: a dose proportionality study.
    Journal of pharmaceutical sciences, 1989, Volume: 78, Issue:10

    Topics: Adult; Chromatography, High Pressure Liquid; Humans; Male; Mesoridazine; Phenothiazines; Thioridazine

1989
Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: Acetylcholine; Animals; Antidepressive Agents; Binding, Competitive; Corpus Striatum; Dopamine; Dopamine Antagonists; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mesoridazine; Phenothiazines; Rabbits; Receptors, Dopamine; Spiperone; Thioridazine

1989
Comparative anticholinergic properties of thioridazine, mesoridazine and sulforidazine.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: Acetylcholine; Animals; Antidepressive Agents; Atropine; Binding, Competitive; Carbachol; Caudate Nucleus; Cell Membrane; Dopamine; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mesoridazine; Parasympatholytics; Phenothiazines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Thioridazine

1989
Mesoridazine and thioridazine.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:8

    Topics: Humans; Mesoridazine; Receptors, Neurotransmitter; Thioridazine

1987
S-oxidation of thioridazine to psychoactive metabolites: an oral dose-proportionality study in healthy volunteers.
    Drug metabolism and drug interactions, 1988, Volume: 6, Issue:3-4

    Topics: Adult; Dose-Response Relationship, Drug; Half-Life; Humans; Male; Mesoridazine; Oxidation-Reduction; Phenothiazines; Psychotropic Drugs; Thioridazine

1988
Radioreceptor assay and high-performance liquid chromatography yield similar results for serum thioridazine and its major metabolites.
    Therapeutic drug monitoring, 1988, Volume: 10, Issue:2

    Topics: Adult; Antidepressive Agents; Chromatography, High Pressure Liquid; Humans; Mesoridazine; Phenothiazines; Radioligand Assay; Schizophrenia; Thioridazine

1988
Development of a radioimmunoassay procedure for mesoridazine and its comparison with a high-performance liquid chromatographic method.
    Therapeutic drug monitoring, 1987, Volume: 9, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Cross Reactions; Humans; Mesoridazine; Rabbits; Radioimmunoassay; Thioridazine

1987
Synthesis and properties of haptens for the development of radioimmunoassays for thioridazine, mesoridazine, and sulforidazine.
    Pharmaceutical research, 1987, Volume: 4, Issue:3

    Topics: Animals; Antibody Formation; Haptens; Mesoridazine; Phenothiazines; Radioimmunoassay; Thioridazine

1987
Plasma propranolol levels and their effect on plasma thioridazine and haloperidol concentrations.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:3

    Topics: Adult; Aged; Drug Interactions; Haloperidol; Humans; Male; Mesoridazine; Middle Aged; Neurocognitive Disorders; Phenothiazines; Propranolol; Thioridazine

1987
Sulphoxide metabolites of thioridazine in man.
    Xenobiotica; the fate of foreign compounds in biological systems, 1986, Volume: 16, Issue:12

    Topics: Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Female; Humans; Isomerism; Male; Mass Spectrometry; Mesoridazine; Phenothiazines; Sulfoxides; Thioridazine

1986
Rapid death resulting from mesoridazine overdose.
    Veterinary and human toxicology, 1987, Volume: 29, Issue:1

    Topics: Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Male; Mesoridazine; Middle Aged; Thioridazine

1987
Phenolic metabolites of thioridazine in man.
    Xenobiotica; the fate of foreign compounds in biological systems, 1985, Volume: 15, Issue:4

    Topics: Administration, Oral; Antidepressive Agents; Chromatography, Thin Layer; Feces; Female; Humans; Male; Mass Spectrometry; Mesoridazine; Phenols; Phenothiazines; Thioridazine

1985
Tardive dyskinesia and drug therapy in geriatric patients.
    Archives of general psychiatry, 1974, Volume: 30, Issue:3

    Topics: Aged; Chlorpromazine; Diagnosis, Differential; Female; Hospitalization; Hospitals, Psychiatric; Humans; Male; Maryland; Mesoridazine; Middle Aged; Movement Disorders; Neurologic Examination; Perphenazine; Thioridazine; Tranquilizing Agents

1974
Isolation of a possible new metabolite of thioridazine and mesoridazine from human plasma.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:3

    Topics: Chromatography, Gas; Chromatography, Thin Layer; Fluorometry; Humans; Mesoridazine; Schizophrenia; Thioridazine; Time Factors

1974
Plasma neuroleptic and prolactin levels in mentally retarded patients.
    Acta pharmacologica et toxicologica, 1980, Volume: 46, Issue:2

    Topics: Antipsychotic Agents; Female; Haloperidol; Humans; Intellectual Disability; Male; Mesoridazine; Prolactin; Thioridazine

1980
Serum neuroleptic concentrations and tardive dyskinesia.
    Psychopharmacology, 1982, Volume: 76, Issue:4

    Topics: Aged; Antipsychotic Agents; Biotransformation; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Humans; Mesoridazine; Middle Aged; Neurocognitive Disorders; Schizophrenia; Thioridazine

1982
Thioridazine pharmacodynamics: clinical effects may depend upon drug metabolism.
    The Journal of the American Osteopathic Association, 1984, Volume: 84, Issue:1 Suppl

    Topics: Animals; Basal Ganglia; Biotransformation; Cricetinae; Mesoridazine; Rats; Receptors, Dopamine; Thioridazine

1984
Plasma and red cell levels of thioridazine and clinical response in schizophrenia.
    Psychiatry research, 1984, Volume: 12, Issue:4

    Topics: Adult; Dose-Response Relationship, Drug; Erythrocytes; Humans; Mesoridazine; Plasma; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Thioridazine

1984
Greater potency of mesoridazine and sulforidazine compared with the parent compound, thioridazine, on striatal dopamine autoreceptors.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:3

    Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mesoridazine; Phenothiazines; Rabbits; Receptors, Dopamine; Thioridazine

1984
Partitioning of thioridazine and mesoridazine in human blood fractions.
    Methods and findings in experimental and clinical pharmacology, 1984, Volume: 6, Issue:3

    Topics: Blood Proteins; Chromatography, Gas; Erythrocytes; Humans; Mesoridazine; Protein Binding; Spectrometry, Fluorescence; Thioridazine

1984
Effect of anticonvulsants on plasma haloperidol and thioridazine levels.
    The American journal of psychiatry, 1980, Volume: 137, Issue:7

    Topics: Adult; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Haloperidol; Humans; Intellectual Disability; Male; Mesoridazine; Phenobarbital; Phenytoin; Thioridazine

1980
Effects of psychotropic drugs on intelligence test performance of institutionalized mentally retarded adults.
    American journal of mental deficiency, 1981, Volume: 85, Issue:6

    Topics: Adult; Chlorpromazine; Female; Haloperidol; Humans; Intellectual Disability; Intelligence Tests; Lithium; Lithium Carbonate; Male; Mesoridazine; Middle Aged; Psychotropic Drugs; Thioridazine

1981
Simultaneous assay of thioridazine and its major metabolites in plasma at single dosage levels with a novel report of two ring sulfoxides of thioridazine.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:6

    Topics: Chromatography, High Pressure Liquid; Cyclic S-Oxides; Drug Stability; Humans; Mesoridazine; Thioridazine

1983
Comparison of psychotropic drug, response cost, and psychotropic drug plus response cost procedures for controlling institutionalized mentally retarded persons.
    Applied research in mental retardation, 1980, Volume: 1, Issue:3-4

    Topics: Adolescent; Adult; Aged; Behavior Therapy; Chlorpromazine; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Intellectual Disability; Lithium; Male; Mesoridazine; Middle Aged; Psychotropic Drugs; Thioridazine

1980
A pilot of plasma thioridazine and metabolites in chronically treated patients.
    The British journal of psychiatry : the journal of mental science, 1980, Volume: 136

    Topics: Aged; Chromatography, Gas; Female; Humans; Male; Mental Disorders; Mesoridazine; Middle Aged; Radioligand Assay; Receptors, Dopamine; Thioridazine

1980
Identification of lactams as in vitro metabolites of piperidine-type phenothiazine antipsychotic drugs.
    Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:6

    Topics: Animals; Antipsychotic Agents; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dogs; Female; Humans; In Vitro Techniques; Lactams; Liver; Male; Mass Spectrometry; Mesoridazine; Phenothiazines; Piperidines; Rats; Rats, Sprague-Dawley; Thioridazine

1996
Pharmacokinetic interaction of fluvoxamine and thioridazine in schizophrenic patients.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:6

    Topics: Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Drug Interactions; Fluvoxamine; Humans; Male; Mesoridazine; Middle Aged; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Thioridazine

1999
Use of the mesoridazine/thioridazine ratio as a marker for CYP2D6 enzyme activity.
    Therapeutic drug monitoring, 2000, Volume: 22, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Biomarkers; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Female; Humans; Male; Mesoridazine; Middle Aged; Thioridazine

2000
Thioridazine (Mellaril) and mesoridazine (Serentil): prolongation of the QTc interval.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2001, Jan-09, Volume: 164, Issue:1

    Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Contraindications; Heart Conduction System; Humans; Long QT Syndrome; Mesoridazine; Schizophrenia; Thioridazine

2001
Diastereotopic analysis of mesoridazine besylate (Serentil).
    Chirality, 2004, Volume: 16, Issue:8

    Topics: Crystallization; Magnetic Resonance Spectroscopy; Mesoridazine; Methylation; Molecular Structure; Stereoisomerism; Thioridazine

2004
Factors affecting drug concentrations and QT interval during thioridazine therapy.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Cross-Sectional Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Dopamine Antagonists; Female; Genetic Variation; Genotype; Heart Conduction System; Humans; Linear Models; Long QT Syndrome; Male; Mesoridazine; Middle Aged; Mixed Function Oxygenases; Risk Factors; Schizophrenia; Sex Factors; Smoking; Thioridazine; White People

2007
Stereoselective analysis of thioridazine-2-sulfoxide and thioridazine-5-sulfoxide: an investigation of rac-thioridazine biotransformation by some endophytic fungi.
    Journal of pharmaceutical and biomedical analysis, 2008, Apr-14, Volume: 46, Issue:5

    Topics: Amylose; Antipsychotic Agents; Aspergillus fumigatus; Asteraceae; Biotransformation; Buffers; Carbamates; Chromatography, High Pressure Liquid; Culture Media; Diethylamines; Ethanol; Ether; Fungi; Hexanes; Methanol; Phyllachorales; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet; Stereoisomerism; Thioridazine

2008
Absorption and excretion of thioridazine and mesoridazine in man.
    Diseases of the nervous system, 1974, Volume: 35, Issue:11

    Topics: Absorption; Antipsychotic Agents; Feces; Humans; Male; Mesoridazine; Schizophrenia; Thioridazine; Time Factors

1974
Relevance of CYP2D6 -1584C>G polymorphism for thioridazine:mesoridazine plasma concentration ratio in psychiatric patients.
    Pharmacogenomics, 2009, Volume: 10, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Female; Genetic Carrier Screening; Genotype; Humans; Male; Mental Disorders; Mesoridazine; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Substrate Specificity; Thioridazine

2009
Assignment of the absolute configuration at the sulfur atom of thioridazine metabolites by the analysis of their chiroptical properties: the case of thioridazine 2-sulfoxide.
    Journal of pharmaceutical and biomedical analysis, 2010, Sep-05, Volume: 52, Issue:5

    Topics: Chromatography, High Pressure Liquid; Circular Dichroism; Models, Molecular; Molecular Conformation; Stereoisomerism; Thioridazine

2010
Combination of experimental and in silico methods for the assessment of the phototransformation products of the antipsychotic drug/metabolite Mesoridazine.
    The Science of the total environment, 2018, Mar-15, Volume: 618

    Topics: Aliivibrio fischeri; Antipsychotic Agents; Biodegradation, Environmental; Mesoridazine; Photolysis; Thioridazine; Toxicity Tests; Water Pollutants, Chemical

2018