mesoridazine has been researched along with thioridazine in 73 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 47 (64.38) | 18.7374 |
1990's | 7 (9.59) | 18.2507 |
2000's | 14 (19.18) | 29.6817 |
2010's | 5 (6.85) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Hulshoff, A; Perrin, JH | 1 |
Keserü, GM | 1 |
Nagashima, R; Nishikawa, T; Tobita, M | 1 |
Jia, L; Sun, H | 1 |
Ahman, M; Holmén, AG; Wan, H | 1 |
Giordanetto, F; Leach, AG; Zachariae, U | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Sen, S; Sinha, N | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Chou, TC; Fowler, NO; Hanenson, IB; Holmes, JC; McCall, D | 1 |
Blum, A; Forrest, IS; Green, DE; Loeffler, KO; Serra, MT | 2 |
Bowers, PA; Cole, JO; Gardos, G; Tecce, JJ | 1 |
Dinovo, EC; Gottschalk, LA; Nandi, BR | 1 |
Donlon, PT; Tupin, JP | 1 |
Dinovo, EC; Geddes, PG; Gottschalk, LA; Nandi, BR | 1 |
Swett, C | 1 |
Frei, RW; Lindner, W; Santi, W | 1 |
Craig, JC; Gruenke, LD | 1 |
Belpaire, FM; Vandeheeren, FA | 1 |
Belpaire, FM; Bogaert, MG; Vanderheeren, FA | 1 |
Baumann, P; Eap, CB; Koeb, L; Souche, A | 1 |
Berens, K; Cleary, J; Poling, A; Thompson, T | 1 |
Hammarlund-Udenaes, M; Hedberg, A; Lidén, A; Movin, G; Nordin, C; Ring, H; Sjöqvist, F; von Bahr, C | 1 |
Beijersbergen van Henegouwen, GM; Panday, IR; Schoonderwoerd, SA | 1 |
Chakraborty, BS; Choc, MG; Hawes, EM; Hubbard, JW; Korchinski, ED; McKay, G; Midha, KK; Robinson, WT | 2 |
Cubeddu, LX; Mailman, RB; Niedzwiecki, DM | 3 |
Millichamp, CJ; Singh, NN | 1 |
Gerbino, L; Katz, IR; Kay, SR; Opler, LA; Vital-Herne, J | 1 |
Richelson, E | 1 |
Brown, WA; Rao, ML; Wagner, R | 1 |
Chakraborty, BS; Hawes, EM; Midha, KK | 1 |
Chakraborty, BS; Hawes, EM; Jaworski, TJ; Midha, KK; Sardessai, MS | 1 |
Greendyke, RM; Kanter, DR | 1 |
Crammer, JL; Papadopoulos, AS | 1 |
Siebel, G; Vertrees, JE | 1 |
Gottschalk, LA | 1 |
Cowan, DA; Crammer, JL; Papadopoulos, AS | 1 |
Dillenkoffer, RL; Gallant, DM; Phillips, JH | 1 |
Berner, W; Konzett, H; Lochs, H | 1 |
Crane, GE; Smeets, RA | 1 |
Biener, R; Dinovo, EC; Gottschalk, LA; Noble, EP | 1 |
Auvinen, J; Linnolia, M; Vaisanen, K; Viukari, M | 1 |
Jeste, DV; Linnoila, M; Wagner, RL; Wyatt, RJ | 1 |
Nwokeafor, V; Shvartsburd, A; Smith, RC | 1 |
Lewis, MH; Mailman, RB; Mobilio, JN; Rissmiller, DJ | 1 |
Allen, P; Baumgartner, R; Johnson, R; Ravichandran, GK; Schoolar, JC; Shvartsburd, A; Smith, RC | 1 |
Dinovo, EC; Gottschalk, LA; Pollak, H | 1 |
Auvinen, J; Linnoila, M; Vaisanen, K; Viukari, M | 1 |
Breuning, SE; Davidson, NA | 1 |
Furman, WB; Juenge, EC; Wells, CE | 1 |
Räisänen, P; Rimón, R; Väisänen, K; Viukari, M | 1 |
Breuning, SE; Ferguson, DG; O'Neill, MJ | 1 |
Chand, TG; Crammer, JL; Lader, S; Papadopoulos, AS | 1 |
Baumann, P; Eap, CB; Guentert, TW; Koeb, L; Powell, K; Schãublin-Loidl, M; Stabl, M | 1 |
Chu, KW; Damani, LA; Hawes, EM; Lin, G; Midha, KK | 1 |
Agundez, JA; Benítez, J; Berecz, R; Carrillo, JA; Duran, M; Herraiz, AG; Llerena, A; Ramos, SI | 1 |
Benítez, J; Berecz, R; de la Rubia, A; Llerena, A; Norberto, MJ | 1 |
Dallaire, S | 1 |
Collier, PS; Millership, JS; Morrow, RJ | 1 |
Berecz, R; de la Rubia, A; Dorado, P; Llerena, A; Peñas-Lledó, EM | 1 |
McKay, GA; Salih, IS; Thanacoody, RH; Thomas, SH | 1 |
Daly, AK; Ferrier, IN; Reilly, JG; Thanacoody, RH; Thomas, SH | 1 |
Bonato, PS; Borges, KB; De Souza Borges, W; Pupo, MT | 1 |
Charalampous, KD; Estevez, V; Johnson, PC | 1 |
de la Rubia, A; Dorado, P; LLerena, A; Peñas-LLedó, EM | 1 |
Bertucci, C; Bonato, PS; Borges, KB; Guimarães, LF; Mazzeo, G; Okano, LT; Rosini, C | 1 |
Kümmerer, K; Leder, C; Menz, J; Wilde, ML | 1 |
3 review(s) available for mesoridazine and thioridazine
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacological treatment of self-injurious behavior in mentally retarded persons.
Topics: Adolescent; Anti-Anxiety Agents; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Double-Blind Method; Female; Haloperidol; Humans; Intellectual Disability; Lithium; Lithium Carbonate; Male; Mesoridazine; Methylphenidate; Phenothiazines; Psychotropic Drugs; Reserpine; Self Mutilation; Thioridazine | 1985 |
The pharmacokinetics of some psychoactive drugs and relationships to clinical response.
Topics: Humans; Kinetics; Mental Disorders; Mesoridazine; Psychotropic Drugs; Research; Schizophrenia; Thioridazine | 1985 |
9 trial(s) available for mesoridazine and thioridazine
Article | Year |
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Plasma levels of thioridazine and metabolites are influenced by the debrisoquin hydroxylation phenotype.
Topics: Adult; Antidepressive Agents; Debrisoquin; Humans; Hydroxylation; Male; Mesoridazine; Phenothiazines; Phenotype; Thioridazine | 1991 |
Mesoridazine and thioridazine: clinical effects and blood levels in refractory schizophrenics.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Female; Hospitalization; Humans; Kinetics; Male; Mesoridazine; Psychiatric Status Rating Scales; Receptors, Dopamine; Schizophrenia; Schizophrenic Psychology; Thioridazine | 1986 |
Electrocardiographic evaluation of mesoridazine (Serentil).
Topics: Adult; Cardiovascular System; Clinical Trials as Topic; Electrocardiography; Female; Humans; Male; Mesoridazine; Middle Aged; Phenothiazines; Schizophrenia; Thioridazine; Time Factors; Tranquilizing Agents | 1972 |
Emotionally induced cardiovascular changes in man as a means for the investigation of tranquillizing drugs.
Topics: Adult; Blood Pressure; Forearm; Heart Rate; Hemodynamics; Humans; Male; Mesoridazine; Placebos; Regional Blood Flow; Stress, Psychological; Task Performance and Analysis; Thioridazine; Time Factors | 1973 |
Red blood cell and plasma levels of thioridazine and mesoridazine in schizophrenic patients.
Topics: Adolescent; Adult; Aged; Aging; Chromatography, Gas; Dose-Response Relationship, Drug; Erythrocytes; Half-Life; Humans; Mesoridazine; Middle Aged; Schizophrenia; Spectrometry, Fluorescence; Thioridazine | 1984 |
Haloperidol, thioridazine and placebo in mentally subnormal patients-serum levels and clinical effects.
Topics: Adolescent; Adult; Clinical Trials as Topic; Female; Haloperidol; Humans; Intellectual Disability; Male; Mesoridazine; Middle Aged; Placebos; Psychomotor Agitation; Random Allocation; Thioridazine | 1981 |
Plasma levels of the enantiomers of thioridazine, thioridazine 2-sulfoxide, thioridazine 2-sulfone, and thioridazine 5-sulfoxide in poor and extensive metabolizers of dextromethorphan and mephenytoin.
Topics: Adult; Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Depressive Disorder; Dextromethorphan; Double-Blind Method; Female; Humans; Male; Mephenytoin; Mesoridazine; Middle Aged; Mixed Function Oxygenases; Phenothiazines; Stereoisomerism; Thioridazine | 1996 |
No effect of the CYP1A2*1F genotype on thioridazine, mesoridazine, sulforidazine plasma concentrations in psychiatric patients.
Topics: Alleles; Antipsychotic Agents; Cytochrome P-450 CYP1A2; Debrisoquin; Dose-Response Relationship, Drug; Genotype; Humans; Mental Disorders; Mesoridazine; Phenothiazines; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Smoking; Thioridazine | 2007 |
Comparison of the effects of thioridazine and mesoridazine on the QT interval in healthy adults after single oral doses.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Area Under Curve; Cross-Over Studies; Dopamine Antagonists; Double-Blind Method; Electrocardiography; Female; Heart Conduction System; Humans; Long QT Syndrome; Male; Mesoridazine; Middle Aged; Reference Values; Thioridazine | 2007 |
61 other study(ies) available for mesoridazine and thioridazine
Article | Year |
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Quantitative correlations between albumin binding constants and chromatographic Rm values of phenothiazine derivatives.
Topics: Binding Sites; Chromatography, Thin Layer; Circular Dichroism; Kinetics; Mathematics; Phenothiazines; Protein Binding; Serum Albumin, Bovine; Solubility; Sulfathiazoles | 1977 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs.
Topics: Adrenergic Agonists; Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; Chlorpromazine; Digitalis Glycosides; Diuretics; Electrocardiography; Female; Heart Failure; Humans; Hypotension; Lidocaine; Male; Mesoridazine; Middle Aged; Phenothiazines; Psychotropic Drugs; Thioridazine | 1976 |
Studies on thioridazine and mesoridazine metabolism. II. In vivo metabolism of tritiated drugs in rhesus monkeys.
Topics: Animals; Blood Proteins; Feces; Female; Haplorhini; Macaca mulatta; Male; Mesoridazine; Thioridazine; Time Factors | 1979 |
A CNV typology of chronic schizophrenics and response to drug treatment.
Topics: Adult; Contingent Negative Variation; Electrophysiology; Female; Humans; Male; Mesoridazine; Middle Aged; Schizophrenia; Thioridazine | 1979 |
Studies on thioridazine and mesoridazine metabolism. I. Protein binding.
Topics: Blood Proteins; Humans; Mesoridazine; Protein Binding; Renal Dialysis; Thioridazine | 1979 |
The assay of plasma concentration of thioridazine and its metabolites as a function of time.
Topics: Biotransformation; Chromatography, Gas; Humans; Mesoridazine; Spectrometry, Fluorescence; Thioridazine; Time Factors | 1978 |
Successful suicides with thioridazine and mesoridazine: a result of probable cardiotoxicity.
Topics: Adult; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Arrest; Heart Block; Heart Conduction System; Humans; Male; Mesoridazine; Middle Aged; Suicide; Thioridazine | 1977 |
GLC analysis of thioridazine, mesoridazine, and their metabolites.
Topics: Chromatography, Gas; Fluorometry; Humans; Mesoridazine; Methods; Sulfones; Sulfoxides; Thioridazine; Time Factors | 1976 |
Drug-induced dystonia.
Topics: Adjustment Disorders; Adult; Basal Ganglia Diseases; Chlorpromazine; Chlorprothixene; Female; Fluphenazine; Haloperidol; Humans; Male; Mental Disorders; Mesoridazine; Middle Aged; Perphenazine; Psychotic Disorders; Psychotropic Drugs; Schizophrenia; Thioridazine; Thiothixene; Trifluoperazine | 1975 |
Serentil for chronic brain syndrome.
Topics: Aged; Dementia; Drug Evaluation; Humans; Mesoridazine; Neurocognitive Disorders; Thioridazine | 1975 |
Combined ultraviolet-fluorescence detection in high-pressure liquid chromatography of pharmaceuticals.
Topics: Chromatography, High Pressure Liquid; Mesoridazine; Methods; Oxidation-Reduction; Phenothiazines; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thioridazine | 1975 |
Identification of a metabolite of thioridazine and mesoridazine from human plasma.
Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Thin Layer; Humans; Isomerism; Mass Spectrometry; Mesoridazine; Sulfones; Thioridazine | 1975 |
Albumin binding of thioridazine and some of its metabolites.
Topics: Animals; Cattle; Dialysis; Mesoridazine; Molecular Conformation; Molecular Weight; Protein Binding; Serum Albumin, Bovine; Thioridazine | 1975 |
Binding of thioridazine and some of its metabolites to human serum protein and human albumin.
Topics: Adult; Animals; Blood Proteins; Humans; Male; Mesoridazine; Protein Binding; Serum Albumin; Thioridazine | 1975 |
Light-induced racemization: artifacts in the analysis of the diastereoisomeric pairs of thioridazine 5-sulfoxide in the plasma and urine of patients treated with thioridazine.
Topics: Adult; Antidepressive Agents; Chromatography, High Pressure Liquid; Female; Humans; Light; Male; Mental Disorders; Mesoridazine; Middle Aged; Phenothiazines; Stereoisomerism; Thioridazine | 1991 |
Neuroleptics and learning: effects of haloperidol, molindone, mesoridazine and thioridazine on the behavior of pigeons under a repeated acquisition procedure.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Chlorpromazine; Columbidae; Dose-Response Relationship, Drug; Haloperidol; Learning; Male; Mesoridazine; Molindone; Thioridazine | 1990 |
UVA-induced genetic effects of thioridazine, mesoridazine and sulforidazine: an in vitro study.
Topics: Antidepressive Agents; DNA; DNA Repair; Escherichia coli; Mesoridazine; Peroxidases; Phenothiazines; Thioridazine; Ultraviolet Rays | 1990 |
Single dose kinetics of thioridazine and its two psychoactive metabolites in healthy humans: a dose proportionality study.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Male; Mesoridazine; Phenothiazines; Thioridazine | 1989 |
Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum.
Topics: Acetylcholine; Animals; Antidepressive Agents; Binding, Competitive; Corpus Striatum; Dopamine; Dopamine Antagonists; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mesoridazine; Phenothiazines; Rabbits; Receptors, Dopamine; Spiperone; Thioridazine | 1989 |
Comparative anticholinergic properties of thioridazine, mesoridazine and sulforidazine.
Topics: Acetylcholine; Animals; Antidepressive Agents; Atropine; Binding, Competitive; Carbachol; Caudate Nucleus; Cell Membrane; Dopamine; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mesoridazine; Parasympatholytics; Phenothiazines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Thioridazine | 1989 |
Mesoridazine and thioridazine.
Topics: Humans; Mesoridazine; Receptors, Neurotransmitter; Thioridazine | 1987 |
S-oxidation of thioridazine to psychoactive metabolites: an oral dose-proportionality study in healthy volunteers.
Topics: Adult; Dose-Response Relationship, Drug; Half-Life; Humans; Male; Mesoridazine; Oxidation-Reduction; Phenothiazines; Psychotropic Drugs; Thioridazine | 1988 |
Radioreceptor assay and high-performance liquid chromatography yield similar results for serum thioridazine and its major metabolites.
Topics: Adult; Antidepressive Agents; Chromatography, High Pressure Liquid; Humans; Mesoridazine; Phenothiazines; Radioligand Assay; Schizophrenia; Thioridazine | 1988 |
Development of a radioimmunoassay procedure for mesoridazine and its comparison with a high-performance liquid chromatographic method.
Topics: Animals; Chromatography, High Pressure Liquid; Cross Reactions; Humans; Mesoridazine; Rabbits; Radioimmunoassay; Thioridazine | 1987 |
Synthesis and properties of haptens for the development of radioimmunoassays for thioridazine, mesoridazine, and sulforidazine.
Topics: Animals; Antibody Formation; Haptens; Mesoridazine; Phenothiazines; Radioimmunoassay; Thioridazine | 1987 |
Plasma propranolol levels and their effect on plasma thioridazine and haloperidol concentrations.
Topics: Adult; Aged; Drug Interactions; Haloperidol; Humans; Male; Mesoridazine; Middle Aged; Neurocognitive Disorders; Phenothiazines; Propranolol; Thioridazine | 1987 |
Sulphoxide metabolites of thioridazine in man.
Topics: Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Female; Humans; Isomerism; Male; Mass Spectrometry; Mesoridazine; Phenothiazines; Sulfoxides; Thioridazine | 1986 |
Rapid death resulting from mesoridazine overdose.
Topics: Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Male; Mesoridazine; Middle Aged; Thioridazine | 1987 |
Phenolic metabolites of thioridazine in man.
Topics: Administration, Oral; Antidepressive Agents; Chromatography, Thin Layer; Feces; Female; Humans; Male; Mass Spectrometry; Mesoridazine; Phenols; Phenothiazines; Thioridazine | 1985 |
Tardive dyskinesia and drug therapy in geriatric patients.
Topics: Aged; Chlorpromazine; Diagnosis, Differential; Female; Hospitalization; Hospitals, Psychiatric; Humans; Male; Maryland; Mesoridazine; Middle Aged; Movement Disorders; Neurologic Examination; Perphenazine; Thioridazine; Tranquilizing Agents | 1974 |
Isolation of a possible new metabolite of thioridazine and mesoridazine from human plasma.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Fluorometry; Humans; Mesoridazine; Schizophrenia; Thioridazine; Time Factors | 1974 |
Plasma neuroleptic and prolactin levels in mentally retarded patients.
Topics: Antipsychotic Agents; Female; Haloperidol; Humans; Intellectual Disability; Male; Mesoridazine; Prolactin; Thioridazine | 1980 |
Serum neuroleptic concentrations and tardive dyskinesia.
Topics: Aged; Antipsychotic Agents; Biotransformation; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Humans; Mesoridazine; Middle Aged; Neurocognitive Disorders; Schizophrenia; Thioridazine | 1982 |
Thioridazine pharmacodynamics: clinical effects may depend upon drug metabolism.
Topics: Animals; Basal Ganglia; Biotransformation; Cricetinae; Mesoridazine; Rats; Receptors, Dopamine; Thioridazine | 1984 |
Plasma and red cell levels of thioridazine and clinical response in schizophrenia.
Topics: Adult; Dose-Response Relationship, Drug; Erythrocytes; Humans; Mesoridazine; Plasma; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Thioridazine | 1984 |
Greater potency of mesoridazine and sulforidazine compared with the parent compound, thioridazine, on striatal dopamine autoreceptors.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mesoridazine; Phenothiazines; Rabbits; Receptors, Dopamine; Thioridazine | 1984 |
Partitioning of thioridazine and mesoridazine in human blood fractions.
Topics: Blood Proteins; Chromatography, Gas; Erythrocytes; Humans; Mesoridazine; Protein Binding; Spectrometry, Fluorescence; Thioridazine | 1984 |
Effect of anticonvulsants on plasma haloperidol and thioridazine levels.
Topics: Adult; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Haloperidol; Humans; Intellectual Disability; Male; Mesoridazine; Phenobarbital; Phenytoin; Thioridazine | 1980 |
Effects of psychotropic drugs on intelligence test performance of institutionalized mentally retarded adults.
Topics: Adult; Chlorpromazine; Female; Haloperidol; Humans; Intellectual Disability; Intelligence Tests; Lithium; Lithium Carbonate; Male; Mesoridazine; Middle Aged; Psychotropic Drugs; Thioridazine | 1981 |
Simultaneous assay of thioridazine and its major metabolites in plasma at single dosage levels with a novel report of two ring sulfoxides of thioridazine.
Topics: Chromatography, High Pressure Liquid; Cyclic S-Oxides; Drug Stability; Humans; Mesoridazine; Thioridazine | 1983 |
Comparison of psychotropic drug, response cost, and psychotropic drug plus response cost procedures for controlling institutionalized mentally retarded persons.
Topics: Adolescent; Adult; Aged; Behavior Therapy; Chlorpromazine; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Intellectual Disability; Lithium; Male; Mesoridazine; Middle Aged; Psychotropic Drugs; Thioridazine | 1980 |
A pilot of plasma thioridazine and metabolites in chronically treated patients.
Topics: Aged; Chromatography, Gas; Female; Humans; Male; Mental Disorders; Mesoridazine; Middle Aged; Radioligand Assay; Receptors, Dopamine; Thioridazine | 1980 |
Identification of lactams as in vitro metabolites of piperidine-type phenothiazine antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dogs; Female; Humans; In Vitro Techniques; Lactams; Liver; Male; Mass Spectrometry; Mesoridazine; Phenothiazines; Piperidines; Rats; Rats, Sprague-Dawley; Thioridazine | 1996 |
Pharmacokinetic interaction of fluvoxamine and thioridazine in schizophrenic patients.
Topics: Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Drug Interactions; Fluvoxamine; Humans; Male; Mesoridazine; Middle Aged; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Thioridazine | 1999 |
Use of the mesoridazine/thioridazine ratio as a marker for CYP2D6 enzyme activity.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Biomarkers; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Female; Humans; Male; Mesoridazine; Middle Aged; Thioridazine | 2000 |
Thioridazine (Mellaril) and mesoridazine (Serentil): prolongation of the QTc interval.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Contraindications; Heart Conduction System; Humans; Long QT Syndrome; Mesoridazine; Schizophrenia; Thioridazine | 2001 |
Diastereotopic analysis of mesoridazine besylate (Serentil).
Topics: Crystallization; Magnetic Resonance Spectroscopy; Mesoridazine; Methylation; Molecular Structure; Stereoisomerism; Thioridazine | 2004 |
Factors affecting drug concentrations and QT interval during thioridazine therapy.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Cross-Sectional Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Dopamine Antagonists; Female; Genetic Variation; Genotype; Heart Conduction System; Humans; Linear Models; Long QT Syndrome; Male; Mesoridazine; Middle Aged; Mixed Function Oxygenases; Risk Factors; Schizophrenia; Sex Factors; Smoking; Thioridazine; White People | 2007 |
Stereoselective analysis of thioridazine-2-sulfoxide and thioridazine-5-sulfoxide: an investigation of rac-thioridazine biotransformation by some endophytic fungi.
Topics: Amylose; Antipsychotic Agents; Aspergillus fumigatus; Asteraceae; Biotransformation; Buffers; Carbamates; Chromatography, High Pressure Liquid; Culture Media; Diethylamines; Ethanol; Ether; Fungi; Hexanes; Methanol; Phyllachorales; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet; Stereoisomerism; Thioridazine | 2008 |
Absorption and excretion of thioridazine and mesoridazine in man.
Topics: Absorption; Antipsychotic Agents; Feces; Humans; Male; Mesoridazine; Schizophrenia; Thioridazine; Time Factors | 1974 |
Relevance of CYP2D6 -1584C>G polymorphism for thioridazine:mesoridazine plasma concentration ratio in psychiatric patients.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Female; Genetic Carrier Screening; Genotype; Humans; Male; Mental Disorders; Mesoridazine; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Substrate Specificity; Thioridazine | 2009 |
Assignment of the absolute configuration at the sulfur atom of thioridazine metabolites by the analysis of their chiroptical properties: the case of thioridazine 2-sulfoxide.
Topics: Chromatography, High Pressure Liquid; Circular Dichroism; Models, Molecular; Molecular Conformation; Stereoisomerism; Thioridazine | 2010 |
Combination of experimental and in silico methods for the assessment of the phototransformation products of the antipsychotic drug/metabolite Mesoridazine.
Topics: Aliivibrio fischeri; Antipsychotic Agents; Biodegradation, Environmental; Mesoridazine; Photolysis; Thioridazine; Toxicity Tests; Water Pollutants, Chemical | 2018 |