Page last updated: 2024-09-05

mesembrine and mesembrenone

mesembrine has been researched along with mesembrenone in 4 studies

Compound Research Comparison

Studies
(mesembrine)
Trials
(mesembrine)
Recent Studies (post-2010)
(mesembrine)
Studies
(mesembrenone)
Trials
(mesembrenone)
Recent Studies (post-2010) (mesembrenone)
28017707

Protein Interaction Comparison

ProteinTaxonomymesembrine (IC50)mesembrenone (IC50)
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.47

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Maurer, HH; Meyer, GM; Wink, CS; Zapp, J1
Abe, N; Ashfaq, MK; Avula, B; Khan, IA; Khan, SI; Manda, VK1
Bennett, AC; López, V; Smith, C; Van Camp, A1
Agoni, C; Budzynska, B; Chen, W; Enslin, GM; Maphanga, VB; Skalicka-Wozniak, K; Skiba, A; Viljoen, AM1

Other Studies

4 other study(ies) available for mesembrine and mesembrenone

ArticleYear
GC-MS, LC-MS(n), LC-high resolution-MS(n), and NMR studies on the metabolism and toxicological detection of mesembrine and mesembrenone, the main alkaloids of the legal high "Kanna" isolated from Sceletium tortuosum.
    Analytical and bioanalytical chemistry, 2015, Volume: 407, Issue:3

    Topics: Aizoaceae; Animals; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Humans; Indole Alkaloids; Liver; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Medicine, African Traditional; Molecular Structure; Rats, Wistar; Reference Standards

2015
Quantification of mesembrine and mesembrenone in mouse plasma using UHPLC-QToF-MS: Application to a pharmacokinetic study.
    Biomedical chromatography : BMC, 2017, Volume: 31, Issue:3

    Topics: Alkaloids; Animals; Chromatography, High Pressure Liquid; Indole Alkaloids; Mass Spectrometry; Mice

2017
Sceletium tortuosum may delay chronic disease progression via alkaloid-dependent antioxidant or anti-inflammatory action.
    Journal of physiology and biochemistry, 2018, Volume: 74, Issue:4

    Topics: Acetylcholinesterase; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Astrocytes; Cell Line; Cell Survival; Cholinesterase Inhibitors; Cytokines; Drug Discovery; Enzyme Inhibitors; Ethnopharmacology; GPI-Linked Proteins; Humans; Indole Alkaloids; Lipopolysaccharides; Medicine, African Traditional; Mesembryanthemum; Monophenol Monooxygenase; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Plant Extracts

2018
Mesembryanthemum tortuosum L. alkaloids modify anxiety-like behaviour in a zebrafish model.
    Journal of ethnopharmacology, 2022, May-23, Volume: 290

    Topics: Alkaloids; Animals; Anxiety; Indole Alkaloids; Locomotion; Maximum Tolerated Dose; Mesembryanthemum; Molecular Docking Simulation; Plant Extracts; Selective Serotonin Reuptake Inhibitors; Zebrafish

2022