mesalamine has been researched along with olsalazine in 79 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (20.25) | 18.7374 |
| 1990's | 39 (49.37) | 18.2507 |
| 2000's | 14 (17.72) | 29.6817 |
| 2010's | 9 (11.39) | 24.3611 |
| 2020's | 1 (1.27) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Guo, XX; Han, X; Hong, T; Hu, Y; Liu, H; Qi, Y; Sun, J; Wang, L; Wu, F; Yu, J; Zhang, T; Zhang, W; Zhou, Y | 1 |
| Allgayer, H; Böhne, P; Gugler, R; Höfer, P; Kruis, W; Schmidt, M | 1 |
| Drab, EA; Linder, JS; Rubin, DB; Sabesin, SM; Sharon, P; Weidman, SW | 1 |
| Giaffer, MH; Holdsworth, CD; O'Brien, CJ | 1 |
| Bergin, CF; Courtney, MG; Keeling, PW; Nunes, DP; O'Driscoll, M; Trimble, V; Weir, DG | 1 |
| Tolia, V | 1 |
| Gait, JE; Simerl, NA | 1 |
| Maier, KP | 1 |
| Crouch, R; Davis, AE; Patterson, F | 1 |
| Rijk, MC; van Schaik, A; van Tongeren, JH | 3 |
| Macrae, K; Record, CO | 1 |
| Aronson, JK; Crotty, B; Jewell, DP; Rosenberg, WM | 1 |
| Gales, BJ; Segars, LW | 1 |
| Barbara, L; Belluzzi, A; Brignola, C; Campieri, M; Gionchetti, P; Guarnieri, C; Iannone, P; Miglioli, M | 2 |
| Ditschuneit, H; Horn, H; Preclik, G; Stange, EF | 1 |
| Crotty, B; Dalton, HR; Hoang, P; Jewell, DP | 1 |
| Huitfeldt, B; Pettersson, R; Ryde, M | 1 |
| Bukhave, K; Lauritsen, K; Rask-Madsen, J; Staerk Laursen, L; Stokholm, M | 1 |
| Lauritsen, K | 1 |
| Rijk, MC; van Hogezand, RA; van Schaik, A; van Tongeren, JH | 1 |
| Bukhave, K; Lauritsen, K; Rask-Madsen, J; Staerk Laursen, L | 1 |
| van Hees, PA; van Hogezand, RA; van Rossum, JM; van Tongeren, JH; Zwanenburg, B | 1 |
| Gibson, PR; Jewell, DP | 1 |
| Friedman, G | 1 |
| Gustavsson, S; Ryde, M | 1 |
| Cann, PA; Holdsworth, CD; Rao, SS | 1 |
| Breiling, J; Franke, M; Gabbert, H; Goerg, KJ; Meyer zum Büschenfelde, KH; Wanitschke, R | 1 |
| Neal, TM; Vissers, MC; Winterbourn, CC | 1 |
| Sullivan, SN | 1 |
| Elmgreen, J; Nielsen, OH; Verspaget, HW | 1 |
| Järnerot, G | 1 |
| Bukhave, K; Lauritsen, K; Laursen, LS; Rask-Madsen, J | 1 |
| Augustin, AJ; Lutz, J | 1 |
| Abildgaard, K; Christensen, LA; Fallingborg, J; Hansen, SH; Jacobsen, BA; Rasmussen, HH; Rasmussen, SN | 1 |
| Abildgaard, K; Christensen, LA; Fallingborg, J; Ingeman-Nielsen, M; Jacobsen, BA; Rasmussen, HH; Rasmussen, SN | 1 |
| Janowitz, HD; Kornbluth, AA; Mitty, R; Sacks, HS; Salomon, P | 1 |
| Ahnfelt-Rønne, I; Berild, D; Bouchelouche, PN; Nielsen, OH | 1 |
| Gait, JE; Powell, JH; Regalli, G | 1 |
| Allgayer, H; Böhne, P; Gugler, R; Klotz, U; Kruis, W; Rang, S; Retey, J | 1 |
| Ferry, GD | 1 |
| Allgayer, H; Erdmann, E; Kruis, W; Sauerbruch, T; Scheurlen, C | 1 |
| Andersson, S; Corboy, JE; Hopkinson, JM; Miller, LG; Motil, KJ | 1 |
| Rasmussen, SN | 1 |
| Becker, K; Ewe, K; Ueberschaer, B | 1 |
| Brignola, C; Campieri, M; Ferretti, M; Gionchetti, P; Miglioli, M; Rizzello, F; Venturi, A | 1 |
| Karamanolis, DG; Papatheodoridis, GV; Xourgias, V | 1 |
| Campbell, BJ; Dwarakanath, AD; Morris, AI; Rhodes, JM; Stevenson, A; Stretch, GL; Yaqoob, M | 1 |
| Archimandritis, A; Hatzis, G; Konstandinidis, A; Paraskeva, K; Skandalis, N; Tzivras, M | 1 |
| Steinberg, H | 1 |
| Brandes, JW; Ewe, K; Judmaier, G; Krakamp, B; Kruis, W; Lorenz-Mayer, H; Otto, P; Schreiber, S; Schütz, E; Theuer, D | 1 |
| Florholmen, J; Støa-Birketvedt, G | 1 |
| Benoit, R; Bichoffe, A; Dol, L; Grobost, O | 1 |
| Cosnes, J; Elefant, E; Gendre, JP; Marteau, P; Modigliani, R; Rambaud, JC; Tennenbaum, R | 1 |
| Brown, WA; Farmer, KC; Malcontenti-Wilson, C; Misajon, A; O'Brien, PE; Skinner, SA | 1 |
| Berg, KJ; Birketvedt, GS; Fausa, O; Florholmen, J | 1 |
| Freyne, PJ; Kelleher, D; Mahmud, N; O'Hare, N; O'Toole, D; Weir, DG | 1 |
| Mandić, Z; Nigović, B; Simunić, B | 1 |
| Schroeder, KW | 1 |
| Cummings, JH; Edmond, LM; Hopkins, MJ; Magee, EA | 1 |
| Bjorkman, D; Kane, SV; Loftus, EV | 1 |
| Baker, DE; Kane, S | 1 |
| Chang, EB; Hanauer, SB; Kles, KA; Musch, MW; Turner, JR; Vavricka, SR | 1 |
| Sandborn, WJ | 1 |
| Aymaz, S; Buschhausen, L; Krakamp, B; Kruis, W; Weber, M | 1 |
| Mahkam, M | 1 |
| Boulieu, R; Lachaux, A; Le Gall, C; Nguyen, TM | 1 |
| Gao, Y; Kuang, Y; Li, J; Li, X; Shi, J; Xu, B | 1 |
| Erichsen, Jv; Hessmann, M; Hoffmeyer, A; Pahl, A; Sann, H | 1 |
| Dhaneshwar, SS | 1 |
| Hanauer, S; Lim, WC; MacDonald, JK; Wang, Y | 1 |
| Kuriyama, A; Matsumura, M; Urushidani, S | 1 |
| Goumas, C; Karatza, E; Muenster, U; Reppas, C; Vertzoni, M | 1 |
| Feng, Y; Li, Z; Liu, L; Ma, S; Mei, Q; Wang, J; Wang, S; Wang, X; Wang, Y; Xu, Z; Yan, R; Yang, P | 1 |
13 review(s) available for mesalamine and olsalazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Mesalamine and olsalazine: 5-aminosalicylic acid agents for the treatment of inflammatory bowel disease.
Topics: Administration, Oral; Administration, Rectal; Aminosalicylic Acids; Chemistry, Pharmaceutical; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Drug Interactions; Drugs, Investigational; Humans; Mesalamine | 1992 |
Drug treatment and formation of eicosanoids in patients with chronic inflammatory bowel disease.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Inflammatory Bowel Diseases; Leukotriene B4; Mesalamine; Prostaglandins; Sulfasalazine; Thromboxane B2 | 1989 |
Sulfasalazine and new analogues.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Enema; Humans; Mesalamine; Sulfasalazine | 1986 |
Clinical tolerance of olsalazine.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Diarrhea; Humans; Mesalamine | 1988 |
Meta-analysis of the effectiveness of current drug therapy of ulcerative colitis.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Humans; Mesalamine; Placebo Effect; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Steroids; Sulfasalazine; Treatment Outcome | 1993 |
Role of mesalazine in acute and long-term treatment of ulcerative colitis and its complications.
Topics: Acute Disease; Administration, Oral; Administration, Rectal; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Enema; Humans; Mesalamine; Phenylhydrazines; Prodrugs; Sulfasalazine; Time Factors | 2002 |
Systematic review: short-term adverse effects of 5-aminosalicylic acid agents in the treatment of ulcerative colitis.
Topics: Administration, Oral; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Colitis, Ulcerative; Double-Blind Method; Humans; Mesalamine; Phenylhydrazines; Randomized Controlled Trials as Topic | 2004 |
The short- and long-term safety of 5-aminosalicylate products in the treatment of ulcerative colitis.
Topics: Adolescent; Adult; Aminosalicylic Acids; Child; Clinical Trials as Topic; Colitis, Ulcerative; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Labeling; Female; Humans; Male; Mesalamine; Middle Aged; Phenylhydrazines; Product Surveillance, Postmarketing; Sensitivity and Specificity; Sulfasalazine | 2004 |
Treatment of ulcerative colitis with oral mesalamine: advances in drug formulation, efficacy expectations and dose response, compliance, and chemoprevention.
Topics: Administration, Oral; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chemoprevention; Clinical Trials as Topic; Colitis, Ulcerative; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Mesalamine; Patient Compliance; Phenylhydrazines; Remission Induction; Sulfasalazine | 2006 |
Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Clinical Trials as Topic; Colon; Fatty Acids, Omega-3; Heparin, Low-Molecular-Weight; Humans; Inflammatory Bowel Diseases; Mesalamine; Phenylhydrazines; Prodrugs; Sulfasalazine | 2014 |
Aminosalicylates for induction of remission or response in Crohn's disease.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Budesonide; Crohn Disease; Delayed-Action Preparations; Gastrointestinal Agents; Humans; Induction Chemotherapy; Mesalamine; Randomized Controlled Trials as Topic; Sulfasalazine | 2016 |
5-aminosalicylic acid agents for prevention of recurrent diverticulitis: A systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminosalicylic Acids; Anti-Inflammatory Agents; Databases, Bibliographic; Diverticulitis; Female; Humans; Male; Mesalamine; Middle Aged; Phenylhydrazines; Randomized Controlled Trials as Topic; Recurrence; Secondary Prevention; Sulfasalazine; Treatment Outcome; Young Adult | 2018 |
23 trial(s) available for mesalamine and olsalazine
| Article | Year |
|---|---|
Randomised comparison of olsalazine and mesalazine in prevention of relapses in ulcerative colitis.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Female; Humans; Life Tables; Male; Mesalamine; Middle Aged; Patient Compliance; Recurrence; Remission Induction | 1992 |
Disposition of mesalazine from mesalazine-delivering drugs in patients with inflammatory bowel disease, with and without diarrhoea.
Topics: Adult; Aged; Aminosalicylic Acids; Delayed-Action Preparations; Diarrhea; Drug Carriers; Feces; Female; Gastrointestinal Transit; Humans; Inflammatory Bowel Diseases; Male; Mesalamine; Middle Aged; Sulfasalazine | 1992 |
Relative bioavailability of olsalazine from tablets and capsules: a drug targeted for local effect in the colon.
Topics: Adult; Aminosalicylic Acids; Biological Availability; Capsules; Colon; Humans; Mesalamine; Tablets | 1991 |
Disposition of 5-aminosalicylic acid by olsalazine and three mesalazine preparations in patients with ulcerative colitis: comparison of intraluminal colonic concentrations, serum values, and urinary excretion.
Topics: Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Colon; Delayed-Action Preparations; Drug Carriers; Feces; Female; Humans; Male; Mesalamine; Middle Aged | 1990 |
Disposition of 5-aminosalicylic acid from 5-aminosalicylic acid-delivering drugs during accelerated intestinal transit in healthy volunteers.
Topics: Adult; Aminosalicylic Acids; Bisacodyl; Female; Gastrointestinal Transit; Humans; Male; Mesalamine; Middle Aged; Sulfasalazine | 1989 |
Sulfasalazine and new analogues.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Enema; Humans; Mesalamine; Sulfasalazine | 1986 |
Clinical experience of the tolerance of mesalazine and olsalazine in patients intolerant of sulphasalazine.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Female; Humans; Male; Mesalamine; Middle Aged; Sulfapyridine; Sulfasalazine | 1987 |
Disposition of 5-aminosalicylic acid by 5-aminosalicylic acid-delivering compounds.
Topics: Adult; Aminosalicylic Acids; Azo Compounds; Delayed-Action Preparations; Feces; Female; Humans; Male; Mesalamine; Sulfasalazine | 1988 |
Clinical tolerance of olsalazine.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Diarrhea; Humans; Mesalamine | 1988 |
Colonic prostaglandin E2 levels and olsalazine metabolism in relapsing ulcerative colitis: implications for controlled trials in the long term.
Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Colon; Dinoprostone; Female; Follow-Up Studies; Humans; Male; Mesalamine; Recurrence; Time Factors | 1988 |
Comparative bioavailability of 5-aminosalicylic acid from a controlled release preparation and an azo-bond preparation.
Topics: Administration, Oral; Aminosalicylic Acids; Biological Availability; Delayed-Action Preparations; Drug Administration Schedule; Feces; Humans; Mesalamine | 1994 |
Effect of olsalazine and mesalazine on intraluminal pH of the duodenum and proximal jejunum in healthy humans.
Topics: Adolescent; Adult; Aminosalicylic Acids; Duodenum; Female; Humans; Hydrogen-Ion Concentration; Jejunum; Male; Mesalamine | 1994 |
Meta-analysis of the effectiveness of current drug therapy of ulcerative colitis.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Humans; Mesalamine; Placebo Effect; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Steroids; Sulfasalazine; Treatment Outcome | 1993 |
IBD: which 5-ASA drug works where?
Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Mesalamine; Recurrence | 1993 |
Systemic uptake of 5-aminosalicylic acid from olsalazine and eudragit L coated mesalazine in patients with ulcerative colitis in remission.
Topics: Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Colitis, Ulcerative; Convalescence; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Intestinal Absorption; Male; Mesalamine; Metabolic Clearance Rate; Middle Aged; Polymethacrylic Acids | 1996 |
Systemic availability of 5-aminosalicylic acid: comparison of delayed release and an azo-bond preparation.
Topics: Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Colitis, Ulcerative; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Male; Mesalamine; Middle Aged; Prodrugs | 1996 |
Systemic absorption of 5-aminosalicylic acid in patients with inactive ulcerative colitis treated with olsalazine and mesalazine.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aminosalicylic Acids; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Cross-Over Studies; Drug Administration Schedule; Female; Gastroscopy; Humans; Male; Mesalamine; Middle Aged; Treatment Outcome | 1996 |
5-amino salicylic acid absorption and metabolism in ulcerative colitis patients receiving maintenance sulphasalazine, olsalazine or mesalazine.
Topics: Absorption; Acetylation; Acetylglucosaminidase; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Female; Humans; Male; Mesalamine; Middle Aged; Sulfasalazine | 1996 |
Systemic absorption of 5-aminosalicylic acid in patients with inactive ulcerative colitis treated with olsalazine and mesalazine.
Topics: Administration, Oral; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Cross-Over Studies; Female; Humans; Male; Mesalamine; Middle Aged | 1997 |
Olsalazine versus mesalazine in the treatment of mild to moderate ulcerative colitis.
Topics: Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Mesalamine; Middle Aged; Treatment Outcome | 1998 |
The systemic load and efficient delivery of active 5-aminosalicylic acid in patients with ulcerative colitis on treatment with olsalazine or mesalazine.
Topics: Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Colon; Cross-Over Studies; Female; Humans; Male; Mesalamine; Middle Aged | 1999 |
Evaluation of renal function following treatment with 5-aminosalicylic acid derivatives in patients with ulcerative colitis.
Topics: Adult; Albuminuria; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Mesalamine; Middle Aged | 2002 |
[Characterization of proteinuria in patients with ulcerative colitis and therapy with aminosalicylates].
Topics: Acute Disease; Adolescent; Adult; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Female; Humans; Kidney Tubular Necrosis, Acute; Leukocyte Count; Male; Mesalamine; Middle Aged; Proteinuria; Risk Factors | 2006 |
46 other study(ies) available for mesalamine and olsalazine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Discovery of a Bioactive Inhibitor with a New Scaffold for Cystathionine γ-Lyase.
Topics: Animals; Aurintricarboxylic Acid; Catalytic Domain; Cystathionine gamma-Lyase; Drug Discovery; Enzyme Inhibitors; HEK293 Cells; Humans; Male; Mice; Molecular Docking Simulation; Molecular Structure; Nitroquinolines; Protein Binding; Rats, Sprague-Dawley; RAW 264.7 Cells; Structure-Activity Relationship | 2019 |
Superoxide, hydroxyl and fatty acid radical scavenging by aminosalicylates. Direct evaluation with electron spin resonance spectroscopy.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; Hydroxides; Hydroxyl Radical; Inflammatory Bowel Diseases; Linoleic Acid; Linoleic Acids; Mesalamine; Spectrophotometry, Ultraviolet; Superoxides | 1992 |
The effect of sulfasalazine on bovine endothelial cell proliferation and cell cycle phase distribution. Comparison with olsalazine, 5-aminosalicylic acid, and sulfapyridine.
Topics: Aminosalicylic Acids; Animals; Cattle; Cell Count; Cell Cycle; Deoxyuridine; Endothelium, Vascular; Mesalamine; Sulfapyridine; Sulfasalazine; Tetrahydrofolates; Thymidine; Time Factors; Tritium | 1992 |
Clinical tolerance to three 5-aminosalicylic acid releasing preparations in patients with inflammatory bowel disease intolerant or allergic to sulphasalazine.
Topics: Aminosalicylic Acids; Drug Hypersensitivity; Female; Humans; Inflammatory Bowel Diseases; Male; Mesalamine; Phenylhydrazines; Sulfapyridine; Sulfasalazine | 1992 |
Sulfasalazine desensitization in children and adolescents with chronic inflammatory bowel disease.
Topics: Adolescent; Aminosalicylic Acids; Child; Chronic Disease; Desensitization, Immunologic; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Inflammatory Bowel Diseases; Male; Mesalamine; Stevens-Johnson Syndrome; Sulfasalazine | 1992 |
Comparisons of olsalazine and mesalazine in prevention of relapse in ulcerative colitis.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Humans; Mesalamine; Recurrence; Research Design | 1992 |
[Aminosalicylates in chronic inflammatory intestinal diseases and rheumatoid arthritis].
Topics: Aminosalicylic Acids; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Humans; Mesalamine; Sulfasalazine | 1992 |
The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model.
Topics: Adenocarcinoma; Aminosalicylic Acids; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Incidence; Inflammatory Bowel Diseases; Male; Mesalamine; Metronidazole; Neoplasm Invasiveness; Rats; Rats, Wistar; Sulfasalazine | 1992 |
Mesalazine versus olsalazine for prophylaxis of ulcerative colitis relapse.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Humans; Mesalamine; Recurrence | 1992 |
Inhibition of binding of interferon-gamma to its receptor by salicylates used in inflammatory bowel disease.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Cell Line; Depression, Chemical; Dose-Response Relationship, Drug; HLA-DR Antigens; Humans; Inflammatory Bowel Diseases; Interferon-gamma; Mesalamine; Protein Binding; Receptors, Interferon; Tumor Cells, Cultured | 1992 |
Scavenger effect of sulfasalazine, 5-aminosalicylic acid, and olsalazine on superoxide radical generation.
Topics: Aminosalicylic Acids; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; In Vitro Techniques; Luminescent Measurements; Mesalamine; Neutrophils; Spectrophotometry; Sulfasalazine; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
Modulation of arachidonic acid metabolism by olsalazine and other aminosalicylates in leukocytes.
Topics: Aminosalicylic Acids; Arachidonic Acid; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes, Mononuclear; Leukotrienes; Mesalamine; Neutrophils; Prostaglandins; Sulfasalazine | 1991 |
Salicylates used in inflammatory bowel disease and colchicine impair interferon-gamma induced HLA-DR expression.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cell Line; Colchicine; Colon; Epithelium; Flow Cytometry; HLA-DR Antigens; Humans; Inflammatory Bowel Diseases; Interferon-gamma; Male; Mesalamine; Middle Aged; Salicylates | 1992 |
Scavenger effect of sulphasalazine (SASP), 5-aminosalicylic acid (5-ASA), and olsalazine (OAZ)
Topics: Aminosalicylic Acids; Free Radicals; Humans; Mesalamine; Neutrophils; Sulfasalazine; Superoxides | 1990 |
Longterm olsalazine treatment: pharmacokinetics, tolerance and effects on local eicosanoid formation in ulcerative colitis and Crohn's colitis.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Dinoprostone; Feces; Female; Humans; Leukotriene B4; Male; Mesalamine; Middle Aged; Prostaglandins E; Rectum | 1988 |
Disposition of disodium azodisalicylate in healthy subjects. A possible new drug for inflammatory bowel disease.
Topics: Administration, Oral; Aminosalicylic Acids; Crohn Disease; Half-Life; Humans; Kinetics; Mesalamine; Sulfapyridine; Sulfasalazine | 1985 |
Sulphasalazine and derivatives, natural killer activity and ulcerative colitis.
Topics: Aminosalicylic Acids; Catechols; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Indomethacin; Killer Cells, Natural; Lipoxygenase Inhibitors; Masoprocol; Mesalamine; Monocytes; Sulfapyridine; Sulfasalazine | 1985 |
Effect of azodisal sodium on the distribution of a transit marker in the small bowel of the fasted rat.
Topics: Aminosalicylic Acids; Animals; Gastrointestinal Motility; Intestine, Small; Male; Mesalamine; Prostaglandins; Rats; Rats, Inbred Strains; Sulfasalazine; Time Factors | 1986 |
Azodisalicylate (azodisal sodium) causes intestinal secretion. Comparative study of the effect of azodisalicylate, sulfasalazine, 5-aminosalicylic acid and sulfapyridine on the water and electrolyte transfer and the morphology of the rat ileum and colon i
Topics: Aminosalicylic Acids; Animals; Colitis, Ulcerative; Colon; Ileum; Intestinal Absorption; Intestinal Mucosa; Mesalamine; Rats; Rats, Inbred Strains; Sulfapyridine; Sulfasalazine | 1987 |
Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine and olsalazine.
Topics: Aminosalicylic Acids; Antigen-Antibody Complex; Exocytosis; Humans; Mesalamine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sulfapyridine; Sulfasalazine; Superoxides | 1987 |
Sulfasalazine lung. Desensitization to sulfasalazine and treatment with acrylic coated 5-ASA and azodisalicylate.
Topics: Adult; Aminosalicylic Acids; Bronchiolitis Obliterans; Colitis, Ulcerative; Desensitization, Immunologic; Humans; Male; Mesalamine; Pulmonary Eosinophilia; Pulmonary Fibrosis; Sulfasalazine | 1987 |
Disposition of 5-aminosalicylic acid by 5-aminosalicylic acid-delivering compounds.
Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Female; Humans; Male; Mesalamine; Sulfasalazine | 1988 |
Inhibition of intestinal macrophage chemotaxis to leukotriene B4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid.
Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acids; Chemotaxis; Female; Humans; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Macrophages; Male; Mesalamine; Middle Aged; Sulfasalazine | 1988 |
Ischemia reperfusion damage in the gut and its treatment with drugs of the aminosalicylic acid group.
Topics: Aminosalicylic Acids; Animals; Benzaldehydes; Glutathione; Glutathione Disulfide; Hydrazones; Intestinal Mucosa; Intestines; Male; Mesalamine; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Sulfasalazine; Thiobarbituric Acid Reactive Substances | 1994 |
Effect of 5-aminosalicylic acid and analogous substances on superoxide generation and intracellular free calcium in human neutrophilic granulocytes.
Topics: Aminosalicylic Acids; Calcium; Free Radical Scavengers; Free Radicals; Humans; In Vitro Techniques; Mesalamine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sulfapyridine; Sulfasalazine; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Use of mesalamine and olsalazine in ulcerative colitis.
Topics: Aminosalicylic Acids; Colitis, Ulcerative; Humans; Mesalamine | 1993 |
Superoxide inhibition following different stimuli of respiratory burst and metabolism of aminosalicylates in neutrophils.
Topics: Acetylation; Aminosalicylic Acid; Aminosalicylic Acids; Benzaldehydes; Free Radical Scavengers; Humans; Hydrazones; Mesalamine; Neutrophils; Respiratory Burst; Superoxides | 1994 |
Effect of olsalazine and mesalazine on human ileal and colonic (Na+ + K+)-ATPase. A possible diarrhogenic factor?
Topics: Aminosalicylic Acids; Binding, Competitive; Colon, Sigmoid; Diarrhea; Humans; Ileum; Inflammatory Bowel Diseases; Intestinal Mucosa; Mesalamine; Ouabain; Sodium-Potassium-Exchanging ATPase | 1993 |
Disposition of olsalazine and metabolites in breast milk.
Topics: Administration, Oral; Adult; Aminosalicylic Acids; Crohn Disease; Drug Administration Schedule; Female; Humans; Mesalamine; Milk, Human | 1993 |
Bioavailability of controlled release mesalazine (5-ASA) preparations.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Delayed-Action Preparations; Humans; Inflammatory Bowel Diseases; Mesalamine | 1995 |
Efficacy of treatment for ulcerative colitis.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Humans; Mesalamine; Sulfasalazine | 1998 |
[Thrombopenia during 5-ASA treatment (mesalazine and olsalazine)].
Topics: Adolescent; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Mesalamine; Thrombocytopenia | 1999 |
[Pregnancy outcome in inflammatory bowel diseases].
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Crohn Disease; Female; Humans; Inflammatory Bowel Diseases; Mesalamine; Prednisone; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prognosis; Surveys and Questionnaires | 1999 |
5-aminosalicyclic acid and olsalazine inhibit tumor growth in a rodent model of colorectal cancer.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Colorectal Neoplasms; Disease Models, Animal; Male; Mesalamine; Rats; Rats, Sprague-Dawley | 2000 |
Glomerular and tubular renal functions after long-term medication of sulphasalazine, olsalazine, and mesalazine in patients with ulcerative colitis.
Topics: Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Female; Gastrointestinal Agents; Humans; Kidney Diseases; Kidney Function Tests; Male; Mesalamine; Middle Aged; Retrospective Studies; Single-Blind Method; Sulfasalazine; Survivors | 2000 |
Comparison of the electrochemical properties of some colon-specific prodrugs of mesalazine.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colon; Drug Delivery Systems; Electrochemistry; Hydrazines; Hydrogen-Ion Concentration; Mesalamine; Prodrugs | 2002 |
The effect of 5-aminosalicylic acid-containing drugs on sulfide production by sulfate-reducing and amino acid-fermenting bacteria.
Topics: Amino Acids; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Desulfovibrio; Feces; Fermentation; Fusobacterium; Humans; In Vitro Techniques; Inflammatory Bowel Diseases; Mesalamine; Phenylhydrazines; Sulfasalazine; Sulfides | 2003 |
Comparative analysis of the in vitro prosecretory effects of balsalazide, sulfasalazine, olsalazine, and mesalamine in rabbit distal ileum.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Colitis, Ulcerative; Diarrhea; Disease Models, Animal; Gastrointestinal Agents; Ileum; Mesalamine; Phenylhydrazines; Prodrugs; Rabbits; Random Allocation; Sulfasalazine; Tissue Culture Techniques | 2005 |
New pH-sensitive glycopolymers for colon-specific drug delivery.
Topics: Aminosalicylic Acids; Azo Compounds; Calorimetry, Differential Scanning; Colon; Cross-Linking Reagents; Drug Delivery Systems; Free Radicals; Hydrogels; Hydrogen-Ion Concentration; Hydrolysis; Mesalamine; Polymers; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2007 |
High thiopurine metabolite concentrations associated with lymphopenia in inflammatory bowel disease (IBD) pediatric patients receiving aminosalicylates combined with azathioprine.
Topics: Adolescent; Aminosalicylic Acids; Azathioprine; Biotransformation; Child; Child, Preschool; Drug Therapy, Combination; Erythrocytes; Female; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lymphopenia; Male; Mesalamine; Purines; Salicylates; Sulfasalazine | 2010 |
Molecular nanofibers of olsalazine form supramolecular hydrogels for reductive release of an anti-inflammatory agent.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Biocompatible Materials; Drug Delivery Systems; Hydrogels; Mesalamine; Models, Biological; Molecular Structure; Nanofibers; Oxidation-Reduction; Phase Transition; Prodrugs; Water | 2010 |
Efficacy of drugs used in the treatment of IBD and combinations thereof in acute DSS-induced colitis in mice.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Budesonide; Colitis; Colon; Cyclosporine; Dextran Sulfate; Drug Therapy, Combination; Female; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Mesalamine; Mice; Mice, Inbred BALB C; Receptors, Prostaglandin E, EP4 Subtype; Thioguanine | 2013 |
Ex vivo evaluation of degradation rates of metronidazole and olsalazine in distal ileum and in cecum: The impact of prandial state.
Topics: Adult; Aminosalicylic Acids; Bacteria; Cecum; Fasting; Humans; Ileum; Mesalamine; Metronidazole | 2017 |
Pharmacokinetic and gut microbiota analyses revealed the effect of Lactobacillus acidophilus on the metabolism of Olsalazine in ulcerative colitis rats.
Topics: Aminosalicylic Acids; Animals; Colitis, Ulcerative; Gastrointestinal Microbiome; Lactobacillus acidophilus; Mesalamine; Probiotics; Rats | 2022 |