mesalamine and n-acetyl-5-aminosalicylic acid

mesalamine has been researched along with n-acetyl-5-aminosalicylic acid in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (38.60)	18.7374
1990's	27 (47.37)	18.2507
2000's	6 (10.53)	29.6817
2010's	1 (1.75)	24.3611
2020's	1 (1.75)	2.80

Authors

Authors	Studies
Farhat, M; George, RF; Girgis, AS; Katritzky, AR; Naumov, RN; Panda, SS	1
Bennett, A; Evans, BK; Mills, CM; Rhodes, J; Swift, GL; Tavares, IA	1
Lunte, CE; Palsmeier, RK; Radzik, DM	1
Barbier, F; Bogaert, M; De Vos, M; Praet, M; Schoonjans, R; Verdievel, H	1
Ireland, A; Jewell, DP; Priddle, JD	1
Aronson, JK; Crotty, B; Jewell, DP; Rosenberg, WM	1
Chorev, M; Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D	1
Boswell, DJ; Greenfield, SM; Punchard, NA; Thompson, RP	1
De Mey, C; Meineke, I	1
Bennett, A; Bishai, PM; Mani, V; Riley, SA; Tavares, IA	1
Devane, J; Martin, M; Mulligan, S	1
Barbier, F; Beke, R; De Vos, M; De Weerdt, GA; Schoonjans, R; Verdievel, H	1
Grisham, MB	1
Gotthard, R; Norlander, B; Ström, M	2
Abildgaard, K; Bondesen, S; Christensen, LA; Fallingborg, J; Hansen, SH; Hvidberg, EF; Jacobsen, BA; Rasmussen, SN; Sanchez, G	1
Bukhave, K; Lauritsen, K; Rask-Madsen, J; Staerk Laursen, L; Stokholm, M	1
Eichmeier, LS; Elvin, AT; Giesing, DH; Lanman, MB; Lanman, RC; Morrill, B; Yu, DK	1
Granger, DN; Grisham, MB; von Ritter, C	1
Ahnfelt, NO; Allgayer, H; Frank-Holmberg, K; Klotz, U; Kruis, W; Paumgartner, G; Söderberg, HN	1
Rijk, MC; van Hogezand, RA; van Schaik, A; van Tongeren, JH	1
Chungi, VS; Dittert, LW; Shargel, L	1
Bukhave, K; Lauritsen, K; Rask-Madsen, J; Staerk Laursen, L	1
Allgayer, H; Kruis, W; Paumgartner, G; Sonnenbichler, J	1
Bondesen, S; Hansen, SH; Hvidberg, EF; Jacobsen, O; Rasmussen, SN; Tage-Jensen, U	1
Ang, SB; Lee, EJ	1
Ahnfelt-Rønne, I; Bukhave, K; Elmgreen, J; Nielsen, OH	1
Rijk, MC; van Schaik, A; van Tongeren, JH	1
Bakker, JH; van Gorp, JP; van Haelst, UJ; van Hees, PA; van Hogezand, RA; van Lier, HJ; van Tongeren, JH; Wesseling, P	1
Brendel, E; Meineke, I; Osterwald, H; Stüwe, E	1
Csipo, I; Degrell, I; Nagy, E; Szabo, G	1
Evans, BK; Evans, DN; Hughes, BR; Lee, MG; Myers, B; Rhodes, J; Richards, D; Richens, A	1
Brendel, E; Meineke, I; Witsch, D; Zschunke, M	1
Cassidy, MK; Houston, JB	1
Hawkey, CJ; Lo Casto, M	1
Hansen, SH	1
Binder, V; Bondesen, S; Fischer, C; Hansen, SH; Hvidberg, EF; Klotz, U; Maier, K; Rasmussen, SN	1
Fischer, C; Klotz, U; Meese, CO	1
Fischer, C; Klotz, U; Maier, K	1
Herzog, R; Leuschner, J	1
Fischer, C; Klotz, U	1
Christensen, LA; Hansen, SH; Rasmussen, SN	1
Ahnfelt-Rønne, I; Berild, D; Bouchelouche, PN; Nielsen, OH	1
Allgayer, H; Böhne, P; Gugler, R; Klotz, U; Kruis, W; Rang, S; Retey, J	1
Goebell, H; Klotz, U; Layer, P; Nehlsen, B	1
Chaussade, S; Sogni, P	1
Carlucci, G; Fanini, D; Frieri, G; Mazzeo, P; Palumbo, G; Pimpo, MT	1
Brignola, C; Campieri, M; Ferretti, M; Gionchetti, P; Miglioli, M; Rizzello, F; Venturi, A	1
Archimandritis, A; Hatzis, G; Konstandinidis, A; Paraskeva, K; Skandalis, N; Tzivras, M	1
Ajjan, RA; Anderson, JC; Hussain, FN; Moustafa, M; Riley, SA	1
Berryman, EL; Meschter, C; Spenard, J; Zerouala, AC	1
Cai, QX; Chen, D; Gao, LP; Zhu, KJ	1
Bortlík, M; Cervený, P; Kubena, A; Lakatos, PL; Lukás, M; Vlcek, J	1
Locatelli, M; Pastorini, E; Roda, A; Roda, E; Roda, G; Simoni, P	1
Attard, TM; Bortey, E; Forbes, WP; Heyman, MB; Pieniaszek, HJ; Pohl, JF; Quiros, JA; Walker, K	1
Furuno, K; Kawano, K; Matsumura, R; Sugihara, N; Yoshimura, S	1
Abe, T; Fukuda, T; Fukuhara, K; Hagihara, Y; Inoue, N; Iwao, Y; Kanai, T; Mikami, Y; Mizuno, S; Mutaguchi, M; Naganuma, M; Nanki, K; Nomura, E; Ogata, H; Sugimoto, S; Sujino, T; Takabayashi, K; Tanemoto, S; Yoshimatsu, Y	1

Trials

11 trial(s) available for mesalamine and n-acetyl-5-aminosalicylic acid

Article	Year
Prandial and diurnal effects on the absorption of orally administered enteric coated 5-aminosalicylic acid (5-ASA). British journal of clinical pharmacology, 1992, Volume: 33, Issue:2 Topics: Administration, Oral; Adult; Aminosalicylic Acids; Circadian Rhythm; Drug Administration Schedule; Eating; Humans; Intestinal Absorption; Male; Mesalamine	1992
Distal ileum and colon: targeted sites for 5-ASA release. European journal of drug metabolism and pharmacokinetics, 1991, Volume: Spec No 3 Topics: Aminosalicylic Acids; Capsules; Colon; Delayed-Action Preparations; Humans; Ileum; Mesalamine	1991
Disposition of 5-aminosalicylic acid by olsalazine and three mesalazine preparations in patients with ulcerative colitis: comparison of intraluminal colonic concentrations, serum values, and urinary excretion. Gut, 1990, Volume: 31, Issue:11 Topics: Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Colon; Delayed-Action Preparations; Drug Carriers; Feces; Female; Humans; Male; Mesalamine; Middle Aged	1990
Pharmacokinetics of a 5-aminosalicylic acid enteric-coated tablet and suppository dosage form. Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:4 Topics: Adult; Aminosalicylic Acids; Feces; Female; Humans; Male; Mesalamine; Spectrometry, Fluorescence; Suppositories; Tablets, Enteric-Coated	1989
Disposition of 5-aminosalicylic acid from 5-aminosalicylic acid-delivering drugs during accelerated intestinal transit in healthy volunteers. Scandinavian journal of gastroenterology, 1989, Volume: 24, Issue:10 Topics: Adult; Aminosalicylic Acids; Bisacodyl; Female; Gastrointestinal Transit; Humans; Male; Mesalamine; Middle Aged; Sulfasalazine	1989
5-Aminosalicylic acid in patients with an ileo-rectal anastomosis. A comparison of the fate of sulfasalazine and Pentasa. European journal of clinical pharmacology, 1986, Volume: 31, Issue:1 Topics: Aminosalicylic Acids; Colectomy; Delayed-Action Preparations; Feces; Humans; Ileum; Mesalamine; Rectum; Sulfasalazine	1986
Double-blind comparison of 5-aminosalicylic acid and acetyl-5-aminosalicylic acid suppositories in patients with idiopathic proctitis. Alimentary pharmacology & therapeutics, 1988, Volume: 2, Issue:1 Topics: Adult; Aminosalicylic Acids; Double-Blind Method; Female; Humans; Male; Mesalamine; Proctitis; Suppositories	1988
Treatment of Crohn's disease with peroral 5-aminosalicylic acid. Gastroenterology, 1983, Volume: 85, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Aminosalicylic Acids; Clinical Trials as Topic; Crohn Disease; Female; Humans; Kinetics; Male; Mesalamine; Middle Aged	1983
Systemic availability of 5-aminosalicylic acid: comparison of delayed release and an azo-bond preparation. Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:4 Topics: Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Colitis, Ulcerative; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Male; Mesalamine; Middle Aged; Prodrugs	1996
Systemic absorption of 5-aminosalicylic acid in patients with inactive ulcerative colitis treated with olsalazine and mesalazine. European journal of gastroenterology & hepatology, 1997, Volume: 9, Issue:7 Topics: Administration, Oral; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Cross-Over Studies; Female; Humans; Male; Mesalamine; Middle Aged	1997
Safety, efficacy, and pharmacokinetics of balsalazide in pediatric patients with mild-to-moderate active ulcerative colitis: results of a randomized, double-blind study. Journal of pediatric gastroenterology and nutrition, 2009, Volume: 49, Issue:5 Topics: Adolescent; Aminosalicylic Acids; Anti-Inflammatory Agents; Child; Colitis, Ulcerative; Colon; Double-Blind Method; Female; Humans; Male; Mesalamine; Phenylhydrazines	2009

Other Studies

46 other study(ies) available for mesalamine and n-acetyl-5-aminosalicylic acid

Article	Year
Synthesis and QSAR study of novel anti-inflammatory active mesalazine-metronidazole conjugates. Bioorganic & medicinal chemistry letters, 2015, Jun-01, Volume: 25, Issue:11 Topics: Animals; Anti-Inflammatory Agents; Indomethacin; Mesalamine; Metronidazole; Mice; Molecular Structure; Quantitative Structure-Activity Relationship; Stomach Ulcer	2015
A pharmacokinetic study of sulphasalazine and two new formulations of mesalazine. Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:2 Topics: Adult; Aminosalicylic Acids; Chemistry, Pharmaceutical; Delayed-Action Preparations; Humans; Male; Mesalamine; Middle Aged; Polymers; Sulfasalazine; Tablets, Enteric-Coated	1992
Investigation of the degradation mechanism of 5-aminosalicylic acid in aqueous solution. Pharmaceutical research, 1992, Volume: 9, Issue:7 Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Biodegradation, Environmental; Drug Stability; Electrochemistry; Mesalamine; Oxidation-Reduction; Solutions; Water	1992
Concentrations of 5-ASA and Ac-5-ASA in human ileocolonic biopsy homogenates after oral 5-ASA preparations. Gut, 1992, Volume: 33, Issue:10 Topics: Administration, Oral; Adolescent; Adult; Aged; Aminosalicylic Acids; Chromatography, High Pressure Liquid; Colon; Colonic Diseases, Functional; Delayed-Action Preparations; Female; Humans; Ileum; Intestinal Mucosa; Male; Mesalamine; Middle Aged; Therapeutic Irrigation; Time Factors	1992
Comparison of 5-aminosalicylic acid and N-acetylaminosalicylic acid uptake by the isolated human colonic epithelial cell. Gut, 1992, Volume: 33, Issue:10 Topics: Aminosalicylic Acids; Cells, Cultured; Chromatography, High Pressure Liquid; Colon; Epithelium; Humans; Mesalamine; Therapeutic Irrigation; Time Factors	1992
Inhibition of binding of interferon-gamma to its receptor by salicylates used in inflammatory bowel disease. Gut, 1992, Volume: 33, Issue:10 Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Cell Line; Depression, Chemical; Dose-Response Relationship, Drug; HLA-DR Antigens; Humans; Inflammatory Bowel Diseases; Interferon-gamma; Mesalamine; Protein Binding; Receptors, Interferon; Tumor Cells, Cultured	1992
Effect of drugs on colonic eicosanoid accumulation in active ulcerative colitis. Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acid; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chloroquine; Colitis, Ulcerative; Colon; Eicosanoids; Female; Humans; Immunosuppressive Agents; Intestinal Mucosa; Ketotifen; Male; Mesalamine; Middle Aged	1992
The effects of 5-aminosalicylic acid and acetyl-5-aminosalicylic acid on lipid peroxidation in erythrocytes and prostaglandin production by mononuclear cells. Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:6 Topics: Aminosalicylic Acids; Dinoprost; Dinoprostone; Epoprostenol; Erythrocyte Membrane; Erythrocytes; Free Radical Scavengers; Humans; Leukocytes, Mononuclear; Lipid Peroxidation; Malondialdehyde; Mesalamine; Prostaglandins	1992
Mesalazine release from coated tablets: effect of dietary fibre. British journal of clinical pharmacology, 1991, Volume: 32, Issue:2 Topics: Adult; Aged; Aminosalicylic Acids; Colitis; Dietary Fiber; Feces; Female; Humans; Hydrogen-Ion Concentration; Male; Mesalamine; Middle Aged; Tablets, Enteric-Coated	1991
High-performance liquid chromatographic assay for the determination of 5-aminosalicylic acid and acetyl-5-aminosalicylic acid concentrations in endoscopic intestinal biopsy in humans. Journal of chromatography, 1991, Mar-08, Volume: 564, Issue:1 Topics: Aminosalicylic Acids; Biopsy; Chromatography, High Pressure Liquid; Endoscopy, Gastrointestinal; Humans; Intestinal Mucosa; Mesalamine	1991
Effect of 5-aminosalicylic acid on ferrous sulfate-mediated damage to deoxyribose. Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12 Topics: Aminosalicylic Acids; Deoxyribose; Drug Interactions; Ferrous Compounds; Mesalamine; Pentetic Acid; Sulfapyridine; Sulfasalazine	1990
Pharmacokinetics of a 5-aminosalicylic acid enteric-coated tablet in patients with Crohn's disease or ulcerative colitis and in healthy volunteers. Alimentary pharmacology & therapeutics, 1990, Volume: 4, Issue:5 Topics: Adolescent; Adult; Aminosalicylic Acids; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Crohn Disease; Feces; Female; Humans; Male; Mesalamine; Middle Aged; Spectrometry, Fluorescence; Tablets, Enteric-Coated	1990
Topical and systemic availability of 5-aminosalicylate: comparisons of three controlled release preparations in man. Alimentary pharmacology & therapeutics, 1990, Volume: 4, Issue:5 Topics: Administration, Topical; Adult; Aminosalicylic Acids; Biological Availability; Body Water; Delayed-Action Preparations; Feces; Female; Humans; Ileostomy; Male; Mesalamine; Middle Aged	1990
Effect of food coadministration on 5-aminosalicylic acid oral suspension bioavailability. Clinical pharmacology and therapeutics, 1990, Volume: 48, Issue:1 Topics: Administration, Oral; Adult; Aminosalicylic Acids; Biological Availability; Feces; Food; Humans; Male; Mesalamine	1990
Sulfasalazine metabolites and dapsone attenuate formyl-methionyl-leucyl-phenylalanine-induced mucosal injury in rat ileum. Gastroenterology, 1989, Volume: 96, Issue:3 Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Dapsone; Ileitis; Intestinal Absorption; Intestinal Mucosa; Mesalamine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Rats; Rats, Inbred Strains; Sulfapyridine; Sulfasalazine	1989
Colonic N-acetylation of 5-aminosalicylic acid in inflammatory bowel disease. Gastroenterology, 1989, Volume: 97, Issue:1 Topics: Acetylation; Aminosalicylic Acids; Chromatography, High Pressure Liquid; Colon; Feces; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Mesalamine; Sulfasalazine	1989
Pharmacokinetics of sulfasalazine metabolites in rats following concomitant oral administration of riboflavin. Pharmaceutical research, 1989, Volume: 6, Issue:12 Topics: Administration, Oral; Aminosalicylic Acids; Animals; Drug Interactions; Half-Life; Male; Mesalamine; Rats; Riboflavin; Sulfapyridine; Sulfasalazine	1989
Longterm olsalazine treatment: pharmacokinetics, tolerance and effects on local eicosanoid formation in ulcerative colitis and Crohn's colitis. Gut, 1988, Volume: 29, Issue:7 Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Dinoprostone; Feces; Female; Humans; Leukotriene B4; Male; Mesalamine; Middle Aged; Prostaglandins E; Rectum	1988
Determination of the pK values of 5-aminosalicylic acid and N-acetylaminosalicylic acid and comparison of the pH dependent lipid-water partition coefficients of sulphasalazine and its metabolites. Arzneimittel-Forschung, 1985, Volume: 35, Issue:9 Topics: Aminosalicylic Acids; Chemical Phenomena; Chemistry, Physical; Hydrogen-Ion Concentration; Mesalamine; Sulfasalazine	1985
Simple and sensitive high-performance liquid chromatographic assay for 5-aminosalicylic acid and acetyl-5-aminosalicylic acid in serum. Journal of chromatography, 1987, Jan-23, Volume: 413 Topics: Aminosalicylic Acids; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Humans; Mesalamine; Sulfasalazine	1987
Sulfasalazine and its anti-inflammatory metabolite, 5-aminosalicylic acid: effect on arachidonic acid metabolism in human neutrophils, and free radical scavenging. Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Biphenyl Compounds; Free Radicals; Humans; Hydrazines; In Vitro Techniques; Intestinal Diseases; Lipoxygenase Inhibitors; Mesalamine; Neutrophils; Picrates; Sulfasalazine	1987
Disposition of 5-aminosalicylic acid by 5-aminosalicylic acid-delivering compounds. Scandinavian journal of gastroenterology. Supplement, 1988, Volume: 148 Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Delayed-Action Preparations; Female; Humans; Male; Mesalamine; Sulfasalazine	1988
Stability of 5-aminosalicylic acid and 5-acetylaminosalicylic acid in plasma. Journal of chromatography, 1988, Nov-18, Volume: 432 Topics: Aminosalicylic Acids; Antioxidants; Chromatography, High Pressure Liquid; Drug Stability; Humans; Hydrogen-Ion Concentration; Mesalamine	1988
High-performance liquid chromatographic assay of 5-aminosalicylic acid and its acetylated metabolite in biological fluids using electrochemical detection. Journal of chromatography, 1988, Mar-04, Volume: 425, Issue:1 Topics: Acetylation; Aminosalicylic Acids; Chromatography, High Pressure Liquid; Colitis; Electrochemistry; Enteritis; Gastritis; Humans; Mesalamine; Spectrophotometry, Ultraviolet	1988
Metabolism and urinary excretion of 5-amino salicylic acid in healthy volunteers when given intravenously or released for absorption at different sites in the gastrointestinal tract. Gut, 1987, Volume: 28, Issue:2 Topics: Adult; Aminosalicylic Acids; Biological Availability; Cecum; Female; Half-Life; Humans; Ileum; Injections, Intravenous; Intestinal Absorption; Intestine, Small; Mesalamine; Middle Aged; Tablets, Enteric-Coated; Time Factors	1987
Simultaneous determination of 5-aminosalicylic acid and 5-acetylaminosalicylic acid by high-performance liquid chromatography. Journal of chromatography, 1987, Jan-09, Volume: 385 Topics: Aminosalicylic Acids; Chromatography, High Pressure Liquid; Humans; Kinetics; Mesalamine	1987
Rate limiting steps in metabolite kinetics: formation of 5-acetylaminosalicylate after administration of 5-aminosalicylate. The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:8 Topics: Aminosalicylic Acids; Animals; Biotransformation; Injections, Intra-Arterial; Intubation, Gastrointestinal; Kinetics; Male; Mesalamine; Rats; Rats, Inbred Strains	1982
Inhibition of prostaglandin synthetase in human rectal mucosa. Gut, 1983, Volume: 24, Issue:3 Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Indomethacin; Intestinal Mucosa; Mesalamine; Prednisolone; Rectum; Sulfapyridine; Sulfasalazine	1983
Assay of 5-aminosalicylate and its acetylated metabolite in biological fluids by high-performance liquid chromatography on dynamically modified silica. Journal of chromatography, 1981, Dec-11, Volume: 226, Issue:2 Topics: Aminosalicylic Acid; Aminosalicylic Acids; Chromatography, High Pressure Liquid; Humans; Ileostomy; Mesalamine; Silicon Dioxide; Spectrometry, Fluorescence	1981
Is N-acetylation of 5-aminosalicylic acid reversible in man? British journal of clinical pharmacology, 1984, Volume: 18, Issue:4 Topics: Acetylation; Adult; Aminosalicylic Acids; Gas Chromatography-Mass Spectrometry; Humans; Male; Mesalamine	1984
Specific measurement of 5-aminosalicylic acid and its acetylated metabolite in human bile. British journal of clinical pharmacology, 1983, Volume: 15, Issue:2 Topics: Aminosalicylic Acids; Bile; Humans; Mesalamine	1983
Pharmacokinetic studies of benzalazine. Arzneimittel-Forschung, 1994, Volume: 44, Issue:12 Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteria, Aerobic; Bacteria, Anaerobic; Benzaldehydes; Biotransformation; Feces; Female; Half-Life; Hydrazones; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestines; Jejunum; Male; Mesalamine; Rats; Rats, Wistar	1994
Radical-derived oxidation products of 5-aminosalicylic acid and N-acetyl-5-aminosalicylic acid. Journal of chromatography. B, Biomedical applications, 1994, Nov-04, Volume: 661, Issue:1 Topics: Aminosalicylic Acids; Chromatography, High Pressure Liquid; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Mercaptoethanol; Mesalamine; Oxidation-Reduction	1994
Disposition of 5-aminosalicylic acid and N-acetyl-5-aminosalicylic acid in fetal and maternal body fluids during treatment with different 5-aminosalicylic acid preparations. Acta obstetricia et gynecologica Scandinavica, 1994, Volume: 73, Issue:5 Topics: Aminosalicylic Acids; Drug Monitoring; Female; Fetal Blood; Fetus; Humans; Inflammatory Bowel Diseases; Mesalamine; Milk, Human; Pregnancy; Pregnancy Complications; Time Factors; Tissue Distribution	1994
Effect of 5-aminosalicylic acid and analogous substances on superoxide generation and intracellular free calcium in human neutrophilic granulocytes. Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:6 Topics: Aminosalicylic Acids; Calcium; Free Radical Scavengers; Free Radicals; Humans; In Vitro Techniques; Mesalamine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sulfapyridine; Sulfasalazine; Superoxides; Tetradecanoylphorbol Acetate	1993
Superoxide inhibition following different stimuli of respiratory burst and metabolism of aminosalicylates in neutrophils. Digestive diseases and sciences, 1994, Volume: 39, Issue:1 Topics: Acetylation; Aminosalicylic Acid; Aminosalicylic Acids; Benzaldehydes; Free Radical Scavengers; Humans; Hydrazones; Mesalamine; Neutrophils; Respiratory Burst; Superoxides	1994
Oroileal transit of slow release 5-aminosalicylic acid. Gut, 1993, Volume: 34, Issue:5 Topics: Administration, Oral; Adult; Aminosalicylic Acids; Delayed-Action Preparations; Gastric Emptying; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Ileum; Jejunum; Male; Mesalamine	1993
Concentrations of 5-ASA and AC-5-ASA in human ileocolonic biopsy homogenates. Gut, 1993, Volume: 34, Issue:5 Topics: Aminosalicylic Acids; Colitis, Ulcerative; Humans; Intestinal Mucosa; Intestines; Mesalamine	1993
Simultaneous determination of 5-aminosalicylic acid, acetyl-5-aminosalicylic acid and 2,5-dihydroxybenzoic acid in endoscopic intestinal biopsy samples in humans by high-performance liquid chromatography with electrochemical detection. Journal of pharmaceutical and biomedical analysis, 1995, Volume: 14, Issue:1-2 Topics: Aminosalicylic Acids; Biopsy; Chromatography, High Pressure Liquid; Electrochemistry; Gentisates; Humans; Hydroxybenzoates; Intestines; Mesalamine	1995
Simple method for the determination of 5-aminosalicylic and N-acetyl-5-aminosalicylic acid in rectal tissue biopsies. Journal of chromatography. B, Biomedical sciences and applications, 1998, Sep-25, Volume: 716, Issue:1-2 Topics: Aminosalicylic Acids; Anhydrides; Biopsy; Chemical Precipitation; Chromatography, High Pressure Liquid; Colitis, Ulcerative; Feces; Humans; Indicators and Reagents; Intestinal Mucosa; Kinetics; Mesalamine; Methanol; Propionates; Rectum; Sensitivity and Specificity; Therapeutic Irrigation	1998
Intrarectal administration of 5-aminosalicylic acid to rabbits and dogs. Human & experimental toxicology, 2002, Volume: 21, Issue:3 Topics: Administration, Rectal; Aminosalicylic Acids; Animals; Area Under Curve; Dogs; Dose-Response Relationship, Drug; Female; Half-Life; Kidney; Male; Mesalamine; Rabbits; Sex Factors	2002
Synthesis, characterization and in vitro release of 5-aminosalicylic acid and 5-acetyl aminosalicylic acid of polyanhydride--P(CBFAS). European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2003, Volume: 55, Issue:2 Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Calorimetry, Differential Scanning; Cecum; Drug Compounding; Drug Stability; Formamides; Gastrointestinal Contents; Hydrolysis; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mesalamine; Molecular Weight; Prodrugs; Rats; Rats, Sprague-Dawley; Salicylates; Spectrophotometry, Infrared; Time Factors	2003
Nonadherence in inflammatory bowel disease: results of factor analysis. Inflammatory bowel diseases, 2007, Volume: 13, Issue:10 Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Chromatography, High Pressure Liquid; Factor Analysis, Statistical; Female; Follow-Up Studies; Humans; Inflammatory Bowel Diseases; Male; Mesalamine; Middle Aged; Patient Compliance; Prognosis; Retrospective Studies; Risk Factors; Surveys and Questionnaires; Treatment Refusal	2007
Development and validation of a HPLC-ESI-MS/MS method for the determination of 5-aminosalicylic acid and its major metabolite N-acetyl-5-aminosalicylic acid in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Sep-01, Volume: 872, Issue:1-2 Topics: Aminosalicylic Acids; Calibration; Chromatography, High Pressure Liquid; Humans; Mesalamine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2008
Inhibitory effect of flavonoids on the efflux of N-acetyl 5-aminosalicylic acid intracellularly formed in Caco-2 cells. Journal of biomedicine & biotechnology, 2009, Volume: 2009 Topics: Aminosalicylic Acids; Biological Transport; Caco-2 Cells; Cell Line, Tumor; Culture Media; Drug Interactions; Flavonoids; Humans; Mesalamine; Multidrug Resistance-Associated Proteins	2009
Mucosal concentrations of N-acetyl-5-aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine. Journal of gastroenterology and hepatology, 2020, Volume: 35, Issue:11 Topics: Adult; Aminosalicylic Acids; Biomarkers; Colitis, Ulcerative; Colon, Sigmoid; Cross-Sectional Studies; Female; Humans; Intestinal Mucosa; Male; Mesalamine; Middle Aged; Prospective Studies; Remission Induction; Sigmoidoscopy; Treatment Outcome	2020