mesalamine and methotrexate

mesalamine has been researched along with methotrexate in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (13.64)18.2507
2000's22 (33.33)29.6817
2010's33 (50.00)24.3611
2020's2 (3.03)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Knuckley, B; Luo, Y; Thompson, PR1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cohen, SA; Daum, F; Glassman, M; Holmes, RD; Markowitz, J; Piccoli, D; Rossi, TM; Treem, WR; Ulshen, MH; Winter, HS1
Stark, ME; Tremaine, WJ1
van Hogezand, RA1
Baratz, M; Gilat, T; Hallak, A; Halpern, Z; Rabau, M; Santo, M; Werbin, N1
Chakravarty, BJ1
Arber, N; Becker, S; Broide, E; Eliakim, R; Fich, A; Gilat, T; Keter, D; Lavy, A; Moshkowitz, M; Odes, S; Oren, R; Patz, J; Pomeranz, I; Reisfeld, I; Shirin, C; Shirin, H; Villa, Y1
Tytgat, GN; van Deventer, SJ1
Adal, K; Dumot, JA; Lashner, BA; Petras, RE1
Kougo, Y1
Cherikuri, A; Donnelly, S; Farrell, RJ; Keeling, PW; Kelleher, D; Long, A; Mahmud, N; Murphy, A; O'Toole, D; Weir, DG1
Faubion, WA; Sandborn, WJ1
Dassopoulos, T; Hanauer, SB1
Rutgeerts, PJ1
Daikh, BE; Ritchlin, CT1
Niemelä, S1
Fleig, WE1
Beglinger, Ch1
Kamm, MA1
Beaugerie, L; Bouhnik, Y; Cosnes, J; Etienney, I; Gendre, JP; Lémann, M; Matuchansky, C; Modigliani, R; Rambaud, JC1
De Pedro-Esteban, A; González-Carro, P; Legaz-Huidobro, ML; Pérez-Roldán, F; Roncero García-Escribano, O; Ruiz-Carrillo, F; Soto-Fernández, S; Valbuena-González, M1
Pierik, M; Rutgeerts, P; Vermeire, S; Vlietinck, R1
Büning, C; Lochs, H1
Lakatos, L; Lakatos, PL1
Akobeng, AK1
Burakoff, R1
Rogler, G; Vavricka, SR1
Feller, ER; Harris, A; Shah, SA1
Croft, NM; Dawson, R; Goodhand, J; Hefferon, M; Lindsay, JO; Swanson, G; Tshuma, N; Wahed, M1
Cury, DB; Moss, AC1
Cabré, E; Domènech, E; Leal-Valdivieso, C; Mañosa, M; Naves, JE; Zabana, Y1
Bischoff, A1
Calderón, R; Delgado, E; Enciso, C; Estrada, S; García-Campos, F; Ramírez de la Piscina, P; Salvador, M; Zabaleta, S1
Ford, AC; Hamlin, PJ; Jackson, EL1
Blumenstein, I; Bock, H; Dignass, A; Filmann, N; Hartmann, F; Herrmann, E; Schröder, O; Stein, J; Tacke, W; Zeuzem, S; Zosel, C1
Blonski, W; Buchner, AM; Lichtenstein, GR1
Half, E; Konikoff, FM; Lev, LB; Naftali, T; Yablecovitch, D; Yablekovitz, D1
Balogh, M; David, G; Erdelyi, Z; Golovics, PA; Horvath, A; Kiss, LS; Komaromi, E; Lakatos, L; Lakatos, PL; Lovasz, BD; Mester, G; Molnar, C; Pandur, T; Szathmari, M; Szipocs, I; Veres, G1
Cheon, JH; Choi, CH; Jang, BI; Kim, YH; Lee, H; Lee, KM; Shin, SJ; Yang, SK; Ye, BD1
Armuzzi, A; D'Haens, G; Griffiths, A; Lukas, M; Pineton de Chambrun, G; Preiss, JC; Reinisch, W; Sladek, M; Van Assche, G1
Chande, N; MacDonald, JK; McDonald, JW; Wang, Y1
El-Matary, W; Griffiths, AM; MacDonald, JK; Vandermeer, B; Wang, Y1
Ballet, V; Bollen, L; Ferrante, M; Gils, A; van Assche, G; Vande Casteele, N; Vermeire, S1
Chande, N; Feagan, BG; Marshall, JK; Nelson, S; Parker, CE; Sandborn, WJ; Seow, CH1
Day, AS; Eliadou, E; Gearry, RB; Inns, SJ; Rowbotham, DS; Schultz, M; Thompson-Fawcett, MW; Walmsley, R1
Grossman, AB; Maxwell, EC1
Charpentier, C; Cheddani, H; Dauchet, L; Dupas, JL; Fumery, M; Gower-Rousseau, C; Marie Bouvier, A; Pariente, B; Peyrin-Biroulet, L; Savoye, G1
Achkar, JP; Brzezinski, A; Garber, A; Horton, N; Lashner, BA; Philpott, J; Shen, B; Wu, X1
Aicart, M; Alcaín, G; Almela, P; Arguelles-Arias, F; Arias-Rivera, ML; Barreiro-de Acosta, M; Barrio, J; Beltrán, B; Benítez, JM; Bermejo, F; Botella, B; Bujanda, L; Busquets, D; Calvet, X; Casanova, MJ; Castaño-Milla, C; Castro, E; Castro, L; Ceballos, D; Chaparro, M; Cortés, X; Domènech, E; Domínguez, M; Domínguez-Antonaya, M; Dueñas, C; Esteve, M; Fernández-Salazar, L; García-Herola, A; García-López, S; García-Planella, E; García-Sánchez, V; García-Sepulcre, MF; Garrido, E; Gisbert, JP; Gómez-García, M; Gomollón, F; González-Lama, Y; Guardiola, J; Gutiérrez, A; Hernández-Martínez, A; Hervías, D; Hinojosa, J; Huguet, JM; Jauregui-Amezaga, A; Khorrami, S; Leo, E; Llaó, J; Lorente-Poyatos, R; Mañosa, M; Marín-Jiménez, I; Marrero, JM; Martín-Arranz, M; Martinez-Montiel, MP; Menacho, M; Merino, O; Monfort, D; Moraleja, I; Muñoz, C; Muñoz, F; Nantes, O; Navarro-Llavat, M; Novella, MT; Opio, V; Pajares, R; Pérez-Calle, JL; Pérez-Martínez, I; Pineda, JR; Ponferrada, A; Ramírez-de la Piscina, P; Ramos, L; Robles-Alonso, V; Rodríguez, C; Rodríguez, GE; Rodríguez-Pérez, A; Rojas-Feria, M; Roncedo, O; Sánchez-Torres, A; Sicilia, B; Taxonera, C; Tosca, J; Van Domselaar, M; Vázquez, JM; Vega-López, AB1
Boice, J; Colombel, JF; Cornillie, F; D'Haens, G; Ghosh, S; Hommes, DW; Huang, Z; Huyck, S; Lindgren, S; Panes, J; Prantera, C; Reinisch, W1
Im, JP; Kim, JW; Lee, H; Lee, KM; Park, DI; Park, JJ; Yang, SK; Ye, BD; Yoon, H; Yoon, SN1
Kandolf-Sekulović, L; Mijušković, Ž; Milenković, Z; Pecelj-Broćić, T; Tarabar, D; Tarabar, O; Tatomirović, Ž1
Jiang, X; Liao, W; Long, S; Lu, N; Shu, X; Zhu, X; Zhu, Z1
Dulai, PS1
Burns, C; Yetto, T1
Afif, W; Bernstein, CN; Bitton, A; Borgaonkar, M; Bressler, B; Chauhan, U; Halloran, B; Jones, J; Kennedy, E; Khanna, R; Leontiadis, GI; Loftus, EV; Marshall, JK; Meddings, J; Moayyedi, P; Murthy, S; Panaccione, R; Plamondon, S; Rosenfeld, G; Schwartz, D; Seow, CH; Steinhart, AH; Targownik, L; Williams, C1
Figueroa Corona, C; Flores Pérez, L; Ibáñez Lazo, P; Quera Pino, R; Sedano Muñoz, R1
Chu, AD; Deodhar, A; Everding, A; Kim, TH; Kishimoto, M; Maksymowych, WP; Pangan, AL; Sieper, J; Song, IH; Sui, Y; van den Bosch, F; van der Heijde, D; Wang, X1
Casanova, MJ; Gisbert, JP; Rojo, E1
Cordeiro, G; Dias, AM; Estevinho, MM; Magro, F1

Reviews

26 review(s) available for mesalamine and methotrexate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Maintenance of symptomatic remission in patients with Crohn's disease.
    Mayo Clinic proceedings, 1993, Volume: 68, Issue:12

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Azathioprine; Clinical Trials as Topic; Crohn Disease; Cyclosporine; Humans; Mercaptopurine; Mesalamine; Methotrexate; Recurrence; Remission Induction; Sulfasalazine

1993
Medical management of patients with difficult-to-treat inflammatory bowel disease.
    The Netherlands journal of medicine, 1994, Volume: 45, Issue:2

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Humans; Mercaptopurine; Mesalamine; Methotrexate; Metronidazole

1994
[Drug treatment of Crohn's disease].
    Nederlands tijdschrift voor geneeskunde, 1998, May-23, Volume: 142, Issue:21

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Budesonide; Clinical Protocols; Crohn Disease; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Mesalamine; Methotrexate; Prednisone; Remission Induction; Treatment Outcome

1998
[Recent progress in therapy of inflammatory bowel diseases].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1999, Sep-10, Volume: 88, Issue:9

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Enteral Nutrition; Humans; Immunoglobulins, Intravenous; Leukapheresis; Mesalamine; Methotrexate; Receptors, Glucocorticoid; Steroids

1999
Clinical pharmacology of inflammatory bowel disease therapies.
    Current gastroenterology reports, 2000, Volume: 2, Issue:6

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Biomarkers; Colitis, Ulcerative; Crohn Disease; Drug Resistance; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Intestinal Mucosa; Mesalamine; Methotrexate; Pharmacogenetics; Receptors, Glucocorticoid

2000
Evolving treatment strategies for inflammatory bowel disease.
    Annual review of medicine, 2001, Volume: 52

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cyclosporins; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mesalamine; Methotrexate; Mycophenolic Acid; Steroids; Tacrolimus

2001
Conventional treatment of Crohn's disease: objectives and outcomes.
    Inflammatory bowel diseases, 2001, Volume: 7 Suppl 1

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Budesonide; Clinical Trials as Topic; Crohn Disease; Humans; Immunosuppressive Agents; Mercaptopurine; Mesalamine; Methotrexate; Prednisone; Quality of Life; Recurrence; Sulfasalazine; Treatment Outcome

2001
Recent advances in the treatment of the seronegative spondyloarthropathies.
    Current rheumatology reports, 2001, Volume: 3, Issue:5

    Topics: Ciprofloxacin; Female; Humans; Male; Mesalamine; Methotrexate; Prognosis; Prohibitins; Randomized Controlled Trials as Topic; Serologic Tests; Severity of Illness Index; Spondylarthropathies; Treatment Outcome; Tumor Necrosis Factor-alpha

2001
[Drug therapy of Crohn disease].
    Duodecim; laaketieteellinen aikakauskirja, 2001, Volume: 117, Issue:8

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Budesonide; Crohn Disease; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Mesalamine; Methotrexate; Secondary Prevention; Treatment Outcome

2001
[Treatment of Crohn's disease].
    Therapeutische Umschau. Revue therapeutique, 2003, Volume: 60, Issue:3

    Topics: Acute Disease; Adjuvants, Immunologic; Adrenal Cortex Hormones; Algorithms; Aminosalicylic Acids; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Budesonide; Case-Control Studies; Clinical Trials as Topic; Crohn Disease; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Mesalamine; Methotrexate; Metronidazole; Osteoporosis; Prednisolone; Prednisone; Randomized Controlled Trials as Topic; Time Factors

2003
Review article: chronic active disease and maintaining remission in Crohn's disease.
    Alimentary pharmacology & therapeutics, 2004, Volume: 20 Suppl 4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Chronic Disease; Crohn Disease; Humans; Infliximab; Mercaptopurine; Mesalamine; Methotrexate; Prognosis; Steroids; Thalidomide

2004
Pharmacogenetics in inflammatory bowel disease.
    World journal of gastroenterology, 2006, Jun-21, Volume: 12, Issue:23

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Crohn Disease; Gastrointestinal Agents; Glucocorticoids; Humans; Immunosuppressive Agents; Infliximab; Mercaptopurine; Mesalamine; Methotrexate; Methyltransferases; Pharmacogenetics; Polymorphism, Genetic; Sulfasalazine; Treatment Outcome

2006
Conventional therapy for Crohn's disease.
    World journal of gastroenterology, 2006, Aug-14, Volume: 12, Issue:30

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Budesonide; Crohn Disease; Glucocorticoids; Humans; Immunosuppressive Agents; Infliximab; Mesalamine; Methotrexate; Nutrition Therapy; Randomized Controlled Trials as Topic; Remission Induction

2006
[Medical therapy of inflammatory bowel diseases: Crohn's disease].
    Orvosi hetilap, 2007, Jun-17, Volume: 148, Issue:24

    Topics: Acute Disease; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Budesonide; Chronic Disease; Crohn Disease; Fistula; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Mesalamine; Methotrexate; Severity of Illness Index

2007
Review article: the evidence base for interventions used to maintain remission in Crohn's disease.
    Alimentary pharmacology & therapeutics, 2008, Jan-01, Volume: 27, Issue:1

    Topics: Adalimumab; Adrenal Cortex Hormones; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Crohn Disease; Enteral Nutrition; Fatty Acids, Omega-3; Humans; Infliximab; Mesalamine; Methotrexate; Natalizumab; Probiotics; Randomized Controlled Trials as Topic

2008
[Treatment of Crohn's disease].
    Praxis, 2009, Jan-21, Volume: 98, Issue:2

    Topics: Adrenal Cortex Hormones; Azathioprine; Biological Products; Colectomy; Combined Modality Therapy; Crohn Disease; Humans; Mercaptopurine; Mesalamine; Methotrexate

2009
Update on the management of Crohn's disease.
    Current gastroenterology reports, 2011, Volume: 13, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Budesonide; Crohn Disease; Humans; Immunologic Factors; Immunosuppressive Agents; Mesalamine; Methotrexate; Natalizumab; Sulfasalazine; Tumor Necrosis Factor-alpha

2011
Methotrexate for induction of remission in ulcerative colitis.
    The Cochrane database of systematic reviews, 2014, Aug-27, Issue:8

    Topics: Administration, Oral; Anti-Inflammatory Agents; Colitis, Ulcerative; Humans; Immunosuppressive Agents; Induction Chemotherapy; Mercaptopurine; Mesalamine; Methotrexate; Randomized Controlled Trials as Topic

2014
Methotrexate for maintenance of remission in ulcerative colitis.
    The Cochrane database of systematic reviews, 2015, Aug-11, Issue:8

    Topics: Administration, Oral; Colitis, Ulcerative; Humans; Immunosuppressive Agents; Maintenance Chemotherapy; Mercaptopurine; Mesalamine; Methotrexate; Sulfasalazine

2015
New Applications for Traditional Drugs in Inflammatory Bowel Disease: What Do Cochrane Reviews Tell Us?
    Inflammatory bowel diseases, 2015, Volume: 21, Issue:12

    Topics: Anti-Inflammatory Agents; Azathioprine; Budesonide; Colitis, Ulcerative; Congresses as Topic; Crohn Disease; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Maintenance Chemotherapy; Mesalamine; Methotrexate; Review Literature as Topic; Secondary Prevention

2015
Advances in Pediatric Inflammatory Bowel Disease.
    Adolescent medicine: state of the art reviews, 2016,Spring, Volume: 27, Issue:1

    Topics: Adalimumab; Adolescent; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Azathioprine; Colitis, Ulcerative; Crohn Disease; Enteral Nutrition; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Mesalamine; Methotrexate; Sulfasalazine; Tacrolimus

2016
[Second Korean Guidelines for the Management of Crohn's Disease].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2017, Jan-25, Volume: 69, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Budesonide; Crohn Disease; Humans; Infliximab; Mercaptopurine; Mesalamine; Methotrexate; Prednisolone; Severity of Illness Index; Tumor Necrosis Factor-alpha

2017
Aminosalicylates, thiopurines and methotrexate in inflammatory bowel disease: Is it possible to discontinue the treatment?
    Gastroenterologia y hepatologia, 2019, Volume: 42, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine; Methotrexate; Remission Induction; Withholding Treatment

2019
Treatment of microscopic colitis: the role of budesonide and new alternatives for refractory patients.
    Revista espanola de enfermedades digestivas, 2020, Volume: 112, Issue:1

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antidiarrheals; Antimetabolites; Azathioprine; Biological Products; Budesonide; Colitis, Collagenous; Colitis, Lymphocytic; Colitis, Microscopic; Diarrhea; Humans; Loperamide; Malabsorption Syndromes; Mesalamine; Methotrexate; Prednisolone; Quality of Life; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Time Factors

2020
Inflammatory Bowel Disease - Non-biological treatment.
    Pharmacological research, 2020, Volume: 160

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Digestive System Surgical Procedures; Gastrointestinal Agents; Humans; Mesalamine; Methotrexate; Tacrolimus; Treatment Outcome

2020

Trials

2 trial(s) available for mesalamine and methotrexate

ArticleYear
Methotrexate in chronic active Crohn's disease: a double-blind, randomized, Israeli multicenter trial.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:12

    Topics: Abdominal Pain; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Chronic Disease; Crohn Disease; Double-Blind Method; Evaluation Studies as Topic; Female; Follow-Up Studies; Health Status; Humans; Immunosuppressive Agents; Israel; Male; Mercaptopurine; Mesalamine; Methotrexate; Middle Aged; Placebos; Recurrence; Remission Induction; Treatment Outcome

1997
Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial.
    Lancet (London, England), 2019, 12-07, Volume: 394, Issue:10214

    Topics: Adult; Antirheumatic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Heterocyclic Compounds, 3-Ring; Humans; Hydroxychloroquine; Janus Kinase Inhibitors; Magnetic Resonance Imaging; Male; Mesalamine; Methotrexate; Middle Aged; Sacroiliac Joint; Spondylitis, Ankylosing; Sulfasalazine; Treatment Outcome

2019

Other Studies

38 other study(ies) available for mesalamine and methotrexate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors.
    Bioorganic & medicinal chemistry, 2008, Jan-15, Volume: 16, Issue:2

    Topics: Arthritis, Rheumatoid; Chlortetracycline; Combinatorial Chemistry Techniques; Enzyme Inhibitors; Fluorescent Dyes; Hydrolases; Minocycline; Models, Biological; Molecular Structure; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Streptomycin; Tetracycline

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Immunology of inflammatory bowel disease: summary of the proceedings of the Subcommittee on Immunosuppressive Use in IBD.
    Journal of pediatric gastroenterology and nutrition, 1991, Volume: 12, Issue:4

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Humans; Immunologic Factors; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lipoxygenase Inhibitors; Mercaptopurine; Mesalamine; Methotrexate; Metronidazole; Steroids

1991
Ileitis after colectomy for ulcerative colitis or carcinoma.
    Gut, 1994, Volume: 35, Issue:3

    Topics: Adult; Aged; Aminosalicylic Acids; Azathioprine; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; Female; Humans; Ileitis; Ileum; Male; Mesalamine; Methotrexate; Middle Aged; Postoperative Complications

1994
Predictors and the rate of medical treatment failure in ulcerative colitis.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:6

    Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Cyclosporine; Discriminant Analysis; Female; Humans; Male; Mesalamine; Methotrexate; Prognosis; Risk Factors; Steroids; Treatment Failure

1993
Sarcoidosis presenting as granulomatous colitis.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colon; Crohn Disease; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents; Mesalamine; Methotrexate; Middle Aged; Sarcoidosis

1998
High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy.
    Gastroenterology, 2000, Volume: 118, Issue:2

    Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azathioprine; Colectomy; Colon; Cyclosporine; Female; Flow Cytometry; Genes, MDR; Glucocorticoids; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Lymphocytes; Male; Mesalamine; Methotrexate; Middle Aged; Reference Values; Treatment Failure

2000
[Maintaining a remission].
    Zeitschrift fur Gastroenterologie, 2003, Volume: 41, Issue:1

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Budesonide; Child; Crohn Disease; Enzyme Inhibitors; Female; Folic Acid Antagonists; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Male; Mercaptopurine; Mesalamine; Meta-Analysis as Topic; Methotrexate; Placebos; Postoperative Care; Prednisolone; Pregnancy; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Risk Factors; Time Factors

2003
Crohn's disease over 20 years after diagnosis in a referral population.
    Gastroenterologie clinique et biologique, 2004, Volume: 28, Issue:12

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Child; Child, Preschool; Crohn Disease; Female; Follow-Up Studies; France; Health Status; Humans; Immunosuppressive Agents; Intestinal Neoplasms; Male; Mesalamine; Methotrexate; Middle Aged; Multivariate Analysis; Parenteral Nutrition, Home; Quality of Life; Recurrence; Reoperation; Retrospective Studies; Surveys and Questionnaires

2004
[Infliximab-induced hepatitis in a patient with Crohn's disease].
    Gastroenterologia y hepatologia, 2006, Volume: 29, Issue:5

    Topics: Acute Disease; Adult; Antibodies, Monoclonal; Azathioprine; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Crohn Disease; Female; Humans; Immunosuppressive Agents; Infliximab; Leukapheresis; Mesalamine; Methotrexate; Pancreatitis; Prednisone; Rectovaginal Fistula

2006
Is it always therapeutically important to distinguish between Crohn's disease and ulcerative colitis?
    Inflammatory bowel diseases, 2008, Volume: 14 Suppl 2

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Humans; Infliximab; Mercaptopurine; Mesalamine; Methotrexate; Remission Induction; Treatment Outcome

2008
Medical therapy of IBD in 2009.
    Medicine and health, Rhode Island, 2009, Volume: 92, Issue:3

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Clinical Trials as Topic; Glucocorticoids; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine; Methotrexate; Natalizumab; Probiotics; Sulfasalazine; Treatment Outcome; Tumor Necrosis Factor-alpha

2009
Inflammatory bowel disease in young people: the case for transitional clinics.
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal; Azathioprine; Case-Control Studies; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Infliximab; Male; Mesalamine; Methotrexate; Middle Aged; Radiation Injuries; Retrospective Studies; Young Adult

2010
Ocular manifestations in a community-based cohort of patients with inflammatory bowel disease.
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:8

    Topics: Acute Disease; Adalimumab; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Cohort Studies; Cyclosporine; Dry Eye Syndromes; Eye Diseases; Female; Humans; Inflammatory Bowel Diseases; Infliximab; Male; Mesalamine; Methotrexate; Middle Aged; Steroids; Treatment Outcome

2010
[Portal hypertension in patients with inflammatory bowel disease].
    Gastroenterologia y hepatologia, 2010, Volume: 33, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Ascites; Crohn Disease; Female; Humans; Hypertension, Portal; Immunosuppressive Agents; Inflammatory Bowel Diseases; Intestinal Pseudo-Obstruction; Liver Cirrhosis; Mesalamine; Mesenteric Veins; Methotrexate; Splenomegaly; Thioguanine; Thrombophilia; Varicose Veins

2010
[Drug therapy of Crohn's disease: slowly increase or start aggressively right away?].
    MMW Fortschritte der Medizin, 2010, Jan-14, Volume: 152, Issue:1-2

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Budesonide; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Gastrointestinal Agents; Glucocorticoids; Humans; Immunosuppressive Agents; Infliximab; Mesalamine; Methotrexate; Practice Guidelines as Topic; Prednisolone; Remission Induction

2010
Infliximab therapy in a patient with refractory ileocolic Crohn's disease and Takayasu arteritis.
    Revista espanola de enfermedades digestivas, 2010, Volume: 102, Issue:2

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Aorta, Abdominal; Aortitis; Azathioprine; Crohn Disease; Drug Resistance; Female; Humans; Immunosuppressive Agents; Infliximab; Magnetic Resonance Angiography; Mesalamine; Methotrexate; Methylprednisolone; Takayasu Arteritis; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha; Young Adult

2010
VSL#3 and remission in active ulcerative colitis: larger studies required.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Bifidobacterium; Colitis, Ulcerative; Diet; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Lactobacillus; Mesalamine; Methotrexate; Probiotics; Randomized Controlled Trials as Topic; Remission Induction; Reproducibility of Results; Severity of Illness Index

2011
Female patients suffering from inflammatory bowel diseases are treated less frequently with immunosuppressive medication and have a higher disease activity: a subgroup analysis of a large multi-centre, prospective, internet-based study.
    Journal of Crohn's & colitis, 2011, Volume: 5, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Budesonide; Colitis, Ulcerative; Crohn Disease; Cross-Sectional Studies; Cyclosporine; Female; Germany; Humans; Immunosuppressive Agents; Infliximab; Male; Mercaptopurine; Mesalamine; Methotrexate; Middle Aged; Practice Patterns, Physicians'; Prospective Studies; Remission Induction; Severity of Illness Index; Sex Factors; Tacrolimus

2011
Treatment of Crohn's disease with cannabis: an observational study.
    The Israel Medical Association journal : IMAJ, 2011, Volume: 13, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cannabis; Crohn Disease; Digestive System Surgical Procedures; Drug Utilization; Female; Humans; Immunosuppressive Agents; Male; Mesalamine; Methotrexate; Middle Aged; Phytotherapy; Retrospective Studies; Severity of Illness Index; Tumor Necrosis Factor-alpha

2011
Has there been a change in the natural history of Crohn's disease? Surgical rates and medical management in a population-based inception cohort from Western Hungary between 1977-2009.
    The American journal of gastroenterology, 2012, Volume: 107, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Chi-Square Distribution; Cohort Studies; Crohn Disease; Female; Gastrointestinal Agents; Humans; Hungary; Immunosuppressive Agents; Incidence; Infliximab; Logistic Models; Male; Mercaptopurine; Mesalamine; Methotrexate; Phenotype; Proportional Hazards Models; Retrospective Studies; Steroids; Sulfasalazine; Surveys and Questionnaires

2012
[Guidelines for the management of Crohn's disease].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2012, Volume: 59, Issue:2

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Budesonide; Crohn Disease; Databases, Factual; Female; Fistula; Humans; Infliximab; Intestinal Perforation; Male; Mercaptopurine; Mesalamine; Methotrexate; Prednisolone; Pregnancy; Recurrence; Risk Factors; Severity of Illness Index; Sulfasalazine

2012
Results of the 2nd scientific workshop of the ECCO (IV): therapeutic strategies to enhance intestinal healing in inflammatory bowel disease.
    Journal of Crohn's & colitis, 2012, Volume: 6, Issue:4

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Endoscopy, Gastrointestinal; Humans; Inflammatory Bowel Diseases; Infliximab; Intestinal Mucosa; Mercaptopurine; Mesalamine; Methotrexate; Treatment Outcome

2012
Thromboembolism as an important complication of inflammatory bowel disease.
    European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:1

    Topics: Adalimumab; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colitis, Ulcerative; Crohn Disease; Female; Humans; Immunosuppressive Agents; Infliximab; Male; Mesalamine; Methotrexate; Middle Aged; Pulmonary Embolism; Recurrence; Retrospective Studies; Severity of Illness Index; Venous Thromboembolism; Venous Thrombosis

2016
New Zealand Society of Gastroenterology Guidelines for the Management of Refractory Ulcerative Colitis.
    The New Zealand medical journal, 2015, Oct-16, Volume: 128, Issue:1423

    Topics: Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Appendectomy; Azathioprine; Colitis, Ulcerative; Cyclosporine; Drug Resistance; Drug Therapy, Combination; Fecal Microbiota Transplantation; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Leukapheresis; Mercaptopurine; Mesalamine; Methotrexate; New Zealand; Pediatrics; Piperidines; Proctocolectomy, Restorative; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Recurrence; Severity of Illness Index; Tacrolimus; Tumor Necrosis Factor-alpha

2015
Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:10

    Topics: Adrenal Cortex Hormones; Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Carcinoma; Colitis, Ulcerative; Colorectal Neoplasms; Crohn Disease; Female; Follow-Up Studies; France; Humans; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Intestinal Neoplasms; Lymphoproliferative Disorders; Male; Mesalamine; Methotrexate; Middle Aged; Myeloproliferative Disorders; Neoplasms; Proportional Hazards Models; Protective Factors; Registries; Retrospective Studies; Risk Factors; Time Factors; Tumor Necrosis Factor-alpha

2016
Impact of Low Immunoglobulin G Levels on Disease Outcomes in Patients with Inflammatory Bowel Diseases.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:11

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Child; Cohort Studies; Colectomy; Colitis, Ulcerative; Colonic Pouches; Crohn Disease; Digestive System Surgical Procedures; Enterostomy; Female; Hospitalization; Humans; Immunoglobulin G; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mesalamine; Methotrexate; Proctocolectomy, Restorative; Prognosis; Retrospective Studies; Young Adult

2016
Evolution After Anti-TNF Discontinuation in Patients With Inflammatory Bowel Disease: A Multicenter Long-Term Follow-Up Study.
    The American journal of gastroenterology, 2017, Volume: 112, Issue:1

    Topics: Adalimumab; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antirheumatic Agents; Colitis, Ulcerative; Colon; Constriction, Pathologic; Crohn Disease; Deprescriptions; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Ileum; Immunologic Factors; Incidence; Inflammatory Bowel Diseases; Infliximab; Male; Mesalamine; Methotrexate; Middle Aged; Proportional Hazards Models; Protective Factors; Recurrence; Remission Induction; Retreatment; Retrospective Studies; Risk Factors; Tumor Necrosis Factor-alpha; Young Adult

2017
Five-year Safety Data From ENCORE, a European Observational Safety Registry for Adults With Crohn's Disease Treated With Infliximab [Remicade®] or Conventional Therapy.
    Journal of Crohn's & colitis, 2017, Jun-01, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Azathioprine; Crohn Disease; Demyelinating Diseases; Drug Substitution; Drug Therapy, Combination; Female; Gastrointestinal Agents; Hematologic Diseases; Humans; Immunosuppressive Agents; Infections; Infliximab; Infusions, Intravenous; Lymphoproliferative Disorders; Male; Mercaptopurine; Mesalamine; Methotrexate; Middle Aged; Mortality; Narcotics; Prednisone; Prospective Studies; Registries; Risk Factors; Sulfasalazine; Time Factors; Young Adult

2017
Cutaneous side effects caused by treatment for inflammatory bowel disease.
    Vojnosanitetski pregled, 2016, Volume: 73, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cyclosporine; Drug Eruptions; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine; Methotrexate; Tumor Necrosis Factor-alpha

2016
Ulcerative colitis followed by the development of typical intestinal Behçet disease: A case report.
    Medicine, 2018, Volume: 97, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Behcet Syndrome; Colitis, Ulcerative; Colonoscopy; Gastrointestinal Tract; Glucocorticoids; Humans; Male; Mesalamine; Methotrexate; Remission Induction; Treatment Outcome

2018
Methotrexate Monotherapy for Induction and Maintenance of Clinical Remission in Ulcerative Colitis: Dead on Arrival.
    Gastroenterology, 2018, Volume: 155, Issue:4

    Topics: Colitis, Ulcerative; Humans; Mercaptopurine; Mesalamine; Methotrexate; Remission Induction

2018
Linear IgA bullous dermatosis associated with ulcerative proctitis: treatment challenge.
    Dermatology online journal, 2018, Jul-15, Volume: 24, Issue:7

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Humans; Immunosuppressive Agents; Linear IgA Bullous Dermatosis; Male; Mesalamine; Methotrexate; Methylprednisolone; Middle Aged; Proctitis; Retreatment

2018
Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Luminal Crohn's Disease.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019, Volume: 17, Issue:9

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Azathioprine; Budesonide; Canada; Crohn Disease; Gastroenterology; Gastrointestinal Agents; Glucocorticoids; Humans; Immunosuppressive Agents; Induction Chemotherapy; Maintenance Chemotherapy; Mesalamine; Methotrexate; Prednisolone; Societies, Medical; Sulfasalazine; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Ustekinumab

2019