mesalamine and leukotriene b4

mesalamine has been researched along with leukotriene b4 in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19909 (30.00)18.7374
1990's18 (60.00)18.2507
2000's2 (6.67)29.6817
2010's1 (3.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carter, L; Granger, DN; Grisham, MB; Jourd'heuil, D; McKnight, W; Meddings, J; Rioux, KP; Wallace, JL; Zimmerman, BJ1
Belluzzi, A; Daneshmend, TK; Everitt, SJ; Hawkey, CJ; Hawthorne, AB; Holmes, GK; Malkinson, C; Shaheen, MZ; Willars, JE1
Hawkey, CJ; Hawthorne, AB; Mahida, YR1
Kleemeyer, K; Peskar, BA; Peskar, BM; Wittenberg, HR1
Gallagher, A; Hawkey, CJ; Hawthorne, AB; Lamming, CE; Mahida, YR1
Guarner, F; Malagelada, JR; Rodriguez, R; Salas, A; Vilaseca, J1
Beck, PL; MacNaughton, WK; Morris, GP; Wallace, JL1
Lauritsen, K1
Edenius, C; Lindgren, JA; Sjöquist, B; Smedegård, G; Tornhamre, S1
Bukhave, K; Lauritsen, K; Rask-Madsen, J; Staerk Laursen, L1
Dreyling, KW; Hoppe, U; Peskar, BA; Peskar, BM; Schaarschmidt, K1
Dreyling, KW; Goebell, H; May, B; Peskar, BM; Schaarschmidt, K1
Elmgreen, J; Nielsen, OH; Verspaget, HW1
Bukhave, K; Lauritsen, K; Laursen, LS; Rask-Madsen, J1
Lobos, E; Stenson, WF1
Bukhave, K; Hansen, TK; Kjeldsen, J; Lauritsen, K; Laursen, LS; Rask-Madsen, J1
Antolín, M; Armengol, JR; Casellas, F; Guarner, F; Malagelada, JR; Papo, M; Segura, RM1
Antolín, M; Armengol, JR; Casellas, F; Guarner, F; Malagelada, JR; Papo, M1
Kawase, S; Kinoshita, N; Nakamaru, K; Sato, M; Sugai, T; Taniguchi, S1
Burch, RM; Lowe, VC; Muhlhauser, RO; Noronha-Blob, L1
Baumeister, B; Kosché, E; Schmidt, C; Vetter, H1
Fukushima, R; Kitano, A; Kobayashi, K; Matsumoto, T; Nakagawa, M; Nakamura, S; Obata, A; Obayashi, M; Okabe, H; Okawa, K; Oshitani, N; Tabata, A; Tomobuchi, M; Watanabe, Y; Yasuda, K1
Baumeister, B; Fels, T; Schmidt, C; Vetter, H1
Dalsgaard, CJ; Haegerstrand, A; Martinsson, T1
Cryer, B; Fine, KD; Sarles, HE1
Martinsson, T1
Aihara, H; Hiwatashi, N1
Harada, K; Inoue, T; Nagakura, N; Oketani, K1
Hamamoto, S; Iwadate, K; Kojima, R; Moriwaki, M; Ohwaki, T1
Haraguchi, Y; Hasegawa, J; Hirayama, M; Hori, Y; Kawabata, Y; Mera, Y; Nakamura, T; Naraki, Y; Ozaki, T; Takei, M; Tanaka, T; Toda, R; Yoshii, K1

Reviews

4 review(s) available for mesalamine and leukotriene b4

ArticleYear
Therapeutic interventions in gastrointestinal disease based on an understanding of inflammatory mediators.
    Agents and actions, 1992, Volume: Spec No

    Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Cytokines; Eicosapentaenoic Acid; Fish Oils; Humans; Interleukins; Leukotriene B4; Mesalamine; Sulfasalazine

1992
Drug treatment and formation of eicosanoids in patients with chronic inflammatory bowel disease.
    Danish medical bulletin, 1989, Volume: 36, Issue:4

    Topics: Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Humans; Inflammatory Bowel Diseases; Leukotriene B4; Mesalamine; Prostaglandins; Sulfasalazine; Thromboxane B2

1989
Effects of mesalazine on the formation of lipoxygenase and cyclooxygenase products.
    Advances in experimental medicine and biology, 1995, Volume: 371B

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Eicosanoids; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Leukotriene B4; Lipoxygenase; Mesalamine; Prostaglandin-Endoperoxide Synthases

1995
[Salazosulfapyridine and 5-aminosalicylic acid agents for the treatment of ulcerative colitis].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Cytokines; Depression, Chemical; Drug Delivery Systems; Histamine Release; HLA-DR Antigens; Humans; Leukotriene B4; Lipid Peroxidation; Mesalamine; Nitric Oxide; Sulfasalazine

1999

Trials

2 trial(s) available for mesalamine and leukotriene b4

ArticleYear
Treatment of ulcerative colitis with fish oil supplementation: a prospective 12 month randomised controlled trial.
    Gut, 1992, Volume: 33, Issue:7

    Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Drug Therapy, Combination; Eicosapentaenoic Acid; Female; Humans; Leukotriene B4; Male; Mesalamine; Middle Aged; Olive Oil; Plant Oils; Prednisolone; Prospective Studies; Remission Induction; Sulfasalazine

1992
Effects of topical 5-aminosalicylic acid and prednisolone on prostaglandin E2 and leukotriene B4 levels determined by equilibrium in vivo dialysis of rectum in relapsing ulcerative colitis.
    Gastroenterology, 1986, Volume: 91, Issue:4

    Topics: Adult; Aged; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Dialysis; Dinoprostone; Double-Blind Method; Enema; Female; Humans; Intestinal Mucosa; Leukotriene B4; Male; Mesalamine; Middle Aged; Prednisolone; Prostaglandins E; Random Allocation; Rectum

1986

Other Studies

24 other study(ies) available for mesalamine and leukotriene b4

ArticleYear
Hemoprotein-dependent production of a neutrophil-activating factor from arachidonic acid.
    The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 2

    Topics: Aminosalicylic Acids; Animals; Arachidonic Acid; Blood Proteins; Chemotactic Factors; Hydrogen Peroxide; Leukotriene B4; Mesalamine; Neutrophils; Rats

1992
[Effect of sulfasalazine and its metabolites on prostaglandin and leukotriene liberation from human synovial tissue].
    Wiener klinische Wochenschrift, 1991, Volume: 103, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chondrocalcinosis; Culture Techniques; Dinoprostone; Humans; Knee Joint; Leukotriene B4; Leukotrienes; Mesalamine; Osteoarthritis; Prostaglandins; SRS-A; Sulfapyridine; Sulfasalazine; Synovial Membrane

1991
5-Aminosalicylic acid is a potent inhibitor of interleukin 1 beta production in organ culture of colonic biopsy specimens from patients with inflammatory bowel disease.
    Gut, 1991, Volume: 32, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acids; Colitis, Ulcerative; Colon; Crohn Disease; Dexamethasone; Female; Humans; Inflammatory Bowel Diseases; Interleukin-1; Leukotriene B4; Male; Mesalamine; Middle Aged; Organ Culture Techniques; Sulfapyridine; Thromboxane B2

1991
Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitis.
    Gastroenterology, 1990, Volume: 98, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Aminosalicylic Acids; Animals; Colitis; Dinoprostone; Indomethacin; Leukotriene B4; Male; Mesalamine; Methacrylates; Pentanoic Acids; Prednisone; Pyridines; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxane-A Synthase; Trinitrobenzenesulfonic Acid

1990
Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.
    Gastroenterology, 1989, Volume: 96, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Aminosalicylic Acids; Animals; Chronic Disease; Colitis; Colon; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mesalamine; Peroxidase; Phenothiazines; Prostaglandins E; Rats; Rats, Inbred Strains; Rioprostil

1989
Effects of sulfasalazine and a sulfasalazine analogue on the formation of lipoxygenase and cyclooxygenase products.
    European journal of pharmacology, 1989, Oct-10, Volume: 169, Issue:2-3

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aminosalicylic Acid; Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Chromatography, High Pressure Liquid; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukocytes; Leukotriene B4; Lipoxygenase; Mesalamine; Prostaglandin-Endoperoxide Synthases; Sulfapyridine; Sulfasalazine; Zymosan

1989
Longterm olsalazine treatment: pharmacokinetics, tolerance and effects on local eicosanoid formation in ulcerative colitis and Crohn's colitis.
    Gut, 1988, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Crohn Disease; Dinoprostone; Feces; Female; Humans; Leukotriene B4; Male; Mesalamine; Middle Aged; Prostaglandins E; Rectum

1988
Leukotrienes in Crohn's disease: effect of sulfasalazine and 5-aminosalicylic acid.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17A

    Topics: Aminosalicylic Acids; Colon; Crohn Disease; Dinoprostone; Humans; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Mesalamine; Peptide Biosynthesis; Prostaglandins E; Sulfasalazine

1987
Possible mode of action of 5-aminosalicylic acid.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:12 Suppl

    Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Leukotriene E4; Mesalamine; Rectum; SRS-A; Sulfasalazine

1987
Inhibition of intestinal macrophage chemotaxis to leukotriene B4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid.
    Alimentary pharmacology & therapeutics, 1988, Volume: 2, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminosalicylic Acids; Chemotaxis; Female; Humans; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Macrophages; Male; Mesalamine; Middle Aged; Sulfasalazine

1988
Sulfasalazine inhibits the synthesis of chemotactic lipids by neutrophils.
    The Journal of clinical investigation, 1982, Volume: 69, Issue:2

    Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotriene B4; Mesalamine; Neutrophils; Sulfasalazine

1982
Effects of thromboxane synthase inhibition on in vivo release of inflammatory mediators in chronic ulcerative colitis.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:3

    Topics: Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Colitis, Ulcerative; Colon; Dinoprostone; Female; Humans; Intestinal Mucosa; Leukotriene B4; Male; Mesalamine; Middle Aged; Pancreatic Elastase; Pentanoic Acids; Pyridines; Thromboxane B2; Thromboxane-A Synthase

1995
Intraluminal colonic release of immunoreactive tumour necrosis factor in chronic ulcerative colitis.
    Clinical science (London, England : 1979), 1994, Volume: 87, Issue:4

    Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Biomarkers; Colitis, Ulcerative; Colon; Colonic Diseases, Functional; Dinoprostone; Female; Humans; Leukotriene B4; Male; Mesalamine; Middle Aged; Tumor Necrosis Factor-alpha

1994
[Effect of mesalazine, an agent for the treatment of idiopathic inflammatory bowel disease, on reactive oxygen metabolites and LTB4 formation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1994, Volume: 104, Issue:6

    Topics: Aminosalicylic Acids; Animals; Depression, Chemical; Dosage Forms; Dose-Response Relationship, Drug; Free Radical Scavengers; In Vitro Techniques; Inflammatory Bowel Diseases; Leukotriene B4; Lipid Peroxidation; Male; Mesalamine; Microsomes, Liver; Neutrophils; Rats; Rats, Sprague-Dawley; Rats, Wistar

1994
NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats.
    Gastroenterology, 1993, Volume: 104, Issue:4

    Topics: Acetates; Acetic Acid; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Colitis; Colon; Dexamethasone; Fluorenes; Glycine; Hydrocortisone; Leucine; Leukotriene B4; Male; Masoprocol; Mesalamine; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Thromboxane B2

1993
Arachidonic acid metabolism and intracellular calcium concentration in inflammatory bowel disease.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:9

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Biopsy; Calcium; Cells, Cultured; Dinoprostone; Female; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Intracellular Fluid; Leukotriene B4; Male; Mesalamine; Radioimmunoassay; Steroids; Sulfasalazine

1995
Distribution and anti-inflammatory effect of mesalazine on carrageenan-induced colitis in the rabbit.
    Clinical and experimental pharmacology & physiology, 1996, Volume: 23, Issue:4

    Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Carrageenan; Colitis; Delayed-Action Preparations; Intestinal Mucosa; Leukotriene B4; Male; Mesalamine; Rabbits; Tissue Distribution

1996
The effect of 5-aminosalicylate and para-aminosalicylate on the synthesis of prostaglandin E2 and leukotriene B4 in isolated colonic mucosal cells.
    Current medical research and opinion, 1996, Volume: 13, Issue:7

    Topics: Adult; Aged; Aminosalicylic Acid; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Colon; Dinoprostone; Female; Humans; Intestinal Mucosa; Leukotriene B4; Male; Mesalamine; Middle Aged

1996
Effects of ropivacaine on eicosanoid release from human granulocytes and endothelial cells in vitro.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Amides; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Eicosanoids; Endothelium, Vascular; Granulocytes; Humans; Hydrocortisone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lidocaine; Mesalamine; Ropivacaine; Thrombin; Zymosan

1997
Diarrhea associated with mesalamine in a patient with chronic nongranulomatous enterocolitis.
    The New England journal of medicine, 1998, Mar-26, Volume: 338, Issue:13

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diarrhea; Dinoprostone; Enterocolitis; Feces; Humans; Leukotriene B4; Male; Mesalamine; Middle Aged

1998
Ropivacaine inhibits serum-induced proliferation of colon adenocarcinoma cells in vitro.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:2

    Topics: Amides; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Cell Division; Dinoprostone; HT29 Cells; Humans; Hydrocortisone; Indoles; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; Membrane Potentials; Mesalamine; Ropivacaine

1999
In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
    European journal of pharmacology, 2001, Jun-22, Volume: 422, Issue:1-3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Benzothiazoles; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Humans; Hydroxyurea; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mesalamine; Methacrylates; Neutrophils; Peritoneal Cavity; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Inbred F344; Sheep; Sulfasalazine; Thiazoles; Thromboxane B2; Thromboxane-A Synthase

2001
[The new experimental ulcerative colitis model in rats induced by subserosal injection of acetic acid].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2001, Volume: 118, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Disease Models, Animal; Inflammation Mediators; Leukotriene B4; Male; Mesalamine; Prednisolone; Rats; Rats, Wistar

2001
Concentration dependence of 5-aminosalicylic acid pharmacological actions in intestinal mucosa after oral administration of a pH-dependent formulation.
    Molecular pharmaceutics, 2011, Aug-01, Volume: 8, Issue:4

    Topics: Administration, Oral; Animals; Cells, Cultured; Chemistry, Pharmaceutical; Dogs; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Intestinal Mucosa; Leukotriene B4; Male; Mesalamine; Neutrophils; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2011
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