Page last updated: 2024-08-20

mequinol and tretinoin

mequinol has been researched along with tretinoin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's2 (13.33)18.2507
2000's9 (60.00)29.6817
2010's1 (6.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Nair, X; Tramposch, KM1
Oliver, I; Sherbet, GV; Thody, AJ1
Nair, X; Parab, P; Suhr, L; Tramposch, KM1
Altman, DJ; Colby, SI; Fleischer, AB; Schwartzel, EH1
Chando, TJ; D'Arienzo, CJ; Everett, DW; Franz, TJ; Gale, PJ; Kripalani, KJ; Lehman, PA; Parab, PV; Schwarzel, EH1
Aslani, FS; Handjani, F; Kasraee, B1
Altman, DJ; Colby, SI; Epinette, WW; Highton, A; Huber, FJ; Lyon, E; Schwartzel, EH1
Bergfelt, L; Camacho, F; Ortonne, JP; Roseeuw, D; Wainwright, N; Westerhof, W1
Jarratt, M1
Draelos, ZD1
Benitez, A; Cardona, L; Epstein, R; Keeling, J; Rendon, M1
Henry, F; Piérard, GE; Piérard-Franchimont, C; Quatresooz, P; Vroome, V1
Friedman, Y1

Reviews

2 review(s) available for mequinol and tretinoin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Mequinol 2%/tretinoin 0.01% topical solution for the treatment of melasma in men: a case series and review of the literature.
    Cutis, 2008, Volume: 81, Issue:2

    Topics: Administration, Topical; Adult; Anisoles; Antioxidants; Facial Dermatoses; Humans; Keratolytic Agents; Male; Melanosis; Middle Aged; Solutions; Treatment Outcome; Tretinoin

2008

Trials

5 trial(s) available for mequinol and tretinoin

ArticleYear
The combination of 2% 4-hydroxyanisole (Mequinol) and 0.01% tretinoin is effective in improving the appearance of solar lentigines and related hyperpigmented lesions in two double-blind multicenter clinical studies.
    Journal of the American Academy of Dermatology, 2000, Volume: 42, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anisoles; Antioxidants; Arm; Double-Blind Method; Drug Therapy, Combination; Facial Dermatoses; Female; Hand Dermatoses; Humans; Hyperpigmentation; Keratolytic Agents; Lentigo; Male; Middle Aged; Severity of Illness Index; Treatment Outcome; Tretinoin

2000
Safety and efficacy of combined use of 4-hydroxyanisole (mequinol) 2%/tretinoin 0.01% solution and sunscreen in solar lentigines.
    Cutis, 2004, Volume: 74, Issue:4

    Topics: Administration, Cutaneous; Adult; Anisoles; Dermatologic Agents; Female; Humans; Hypopigmentation; Keratolytic Agents; Lentigo; Male; Severity of Illness Index; Sunscreening Agents; Time Factors; Treatment Outcome; Tretinoin

2004
Mequinol 2%/tretinoin 0.01% solution: an effective and safe alternative to hydroquinone 3% in the treatment of solar lentigines.
    Cutis, 2004, Volume: 74, Issue:5

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Anisoles; Double-Blind Method; Drug Therapy, Combination; Face; Female; Forearm; Humans; Hydroquinones; Keratolytic Agents; Lentigo; Male; Middle Aged; Treatment Outcome; Tretinoin

2004
The combination of 2% 4-hydroxyanisole (mequinol) and 0.01% tretinoin effectively improves the appearance of solar lentigines in ethnic groups.
    Journal of cosmetic dermatology, 2006, Volume: 5, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anisoles; Antioxidants; Drug Combinations; Ethnicity; Face; Female; Humans; Keratolytic Agents; Lentigo; Male; Middle Aged; Tretinoin

2006
Analytic quantification of the bleaching effect of a 4-hydroxyanisole-tretinoin combination on actinic lentigines.
    Journal of drugs in dermatology : JDD, 2008, Volume: 7, Issue:9

    Topics: Absorptiometry, Photon; Administration, Cutaneous; Aged; Anisoles; Antioxidants; Dermoscopy; Drug Therapy, Combination; Female; Follow-Up Studies; Hand Dermatoses; Humans; Keratolytic Agents; Lentigo; Middle Aged; Skin Aging; Spectrophotometry; Sunlight; Tretinoin; Ultraviolet Rays; Video Recording

2008

Other Studies

8 other study(ies) available for mequinol and tretinoin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
UVB-induced pigmentation in hairless mice as an in vivo assay for topical skin-depigmenting activity.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1989, Volume: 2, Issue:4

    Topics: Animals; Anisoles; Female; Hydroquinones; Mice; Mice, Hairless; Pyrones; Skin; Skin Pigmentation; Tretinoin; Ultraviolet Rays

1989
Cytotoxicity of 4-hydroxyanisole and tyrosinase activity in variant cell lines of B16 melanoma.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:12

    Topics: Animals; Anisoles; Catechol Oxidase; Cell Survival; Ditiocarb; Melanocyte-Stimulating Hormones; Melanoma; Mice; Monophenol Monooxygenase; Tretinoin; Tumor Cells, Cultured

1988
Combination of 4-hydroxyanisole and all-trans retinoic acid produces synergistic skin depigmentation in swine.
    The Journal of investigative dermatology, 1993, Volume: 101, Issue:2

    Topics: Animals; Anisoles; Drug Synergism; Mice; Mice, Hairless; Skin; Skin Absorption; Skin Pigmentation; Swine; Swine, Miniature; Tretinoin; Ultraviolet Rays

1993
Percutaneous absorption of [3H]tretinoin and systemic exposure to mequinol after dermal application of 2% mequinol/0.01% [3H]tretinoin (Solagé) solution in healthy volunteers.
    Biopharmaceutics & drug disposition, 1999, Volume: 20, Issue:6

    Topics: Administration, Topical; Adult; Animals; Anisoles; Antineoplastic Agents; Area Under Curve; Drug Combinations; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Male; Mice; Middle Aged; Rats; Skin Absorption; Tretinoin

1999
Enhancement of the depigmenting effect of hydroquinone and 4-hydroxyanisole by all-trans-retinoic acid (tretinoin): the impairment of glutathione-dependent cytoprotection?
    Dermatology (Basel, Switzerland), 2003, Volume: 206, Issue:4

    Topics: Animals; Anisoles; Drug Therapy, Combination; Enzyme Inhibitors; Glutathione; Glutathione Transferase; Guinea Pigs; Humans; Hydroquinones; Keratolytic Agents; Melanocytes; Skin Pigmentation; Swine; Tretinoin

2003
A promising new treatment for solar lentigines.
    Journal of drugs in dermatology : JDD, 2003, Volume: 2, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anisoles; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hyperpigmentation; Male; Middle Aged; Sunscreening Agents; Tretinoin

2003
Two drugs facing key patent expirations and potential generic entry from July to August 2020.
    Pharmaceutical patent analyst, 2020, Volume: 9, Issue:4

    Topics: Anisoles; Ciprofloxacin; Dexamethasone; Drug Combinations; Drug Industry; Drugs, Generic; Humans; Patents as Topic; Tretinoin; United States

2020