meptazinol has been researched along with naloxone in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (77.78) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Hetherington, MS; Hughes, IE; Lees, A | 1 |
| Wali, FA | 1 |
| Adler, BA; Pasternak, GW; Rodriguez, J | 1 |
| Paciorek, PM; Todd, MH; Waterfall, JF | 1 |
| Chance, E; Paciorek, PM; Todd, MH; Waterfall, JF | 1 |
| Ennis, C; Wyllie, MG | 1 |
| Habte-Michael, A; Teklu, B; Warrell, DA; White, NJ; Wright, DJ | 1 |
| Wright, DJ | 1 |
| Pasternak, GW; Spiegel, K | 1 |
| Duchesne, RJ; Goodall, J; Hughes, IE | 1 |
| Bill, DJ; Hartley, JE; Stephens, RJ; Thompson, AM | 1 |
| Ben-Sreti, MM; Gonzalez, JP; Qureshi, R; Sewell, RD; Spencer, PS | 1 |
| Harmer, M; Rosen, M; Slattery, PJ; Vickers, MD | 1 |
| Barclay, SP; Brown, Z; Robson, PJ; Warrington, SJ | 1 |
| Bille-Hansen, V; Faber, T; Jensen, FM; Madsen, JB | 1 |
2 trial(s) available for meptazinol and naloxone
| Article | Year |
|---|---|
Meptazinol diminishes the Jarisch-Herxheimer reaction of relapsing fever.
Topics: Adolescent; Adult; Azepines; Clinical Trials as Topic; Double-Blind Method; Endotoxins; Fever; Humans; Infusions, Parenteral; Meptazinol; Naloxone; Prednisolone; Relapsing Fever; Spirochaeta; Tetracycline | 1983 |
Reversibility of the analgesic effect of meptazinol in volunteers.
Topics: Adult; Analgesics; Azepines; Dental Pulp; Humans; Ischemia; Male; Meptazinol; Naloxone; Pain; Physical Exertion; Sensory Thresholds; Time Factors | 1983 |
16 other study(ies) available for meptazinol and naloxone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
An investigation of the mechanism involved in the cholinergic action of meptazinol.
Topics: Animals; Atropine; Azepines; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide; Carbachol; Cholinesterase Inhibitors; Cold Temperature; Dimethylphenylpiperazinium Iodide; Drug Synergism; Electric Stimulation; Guinea Pigs; Ileum; Meptazinol; Muscle Contraction; Naloxone; Phrenic Nerve; Tetraethylammonium Compounds | 1987 |
On the cholinergic component of action of meptazinol.
Topics: Acetylcholine; Animals; Azepines; Diaphragm; Dose-Response Relationship, Drug; Fentanyl; Ileum; Male; Meptazinol; Morphine; Muscle Contraction; Naloxone; Rats; Rats, Inbred Strains | 1986 |
Characterization of the opioid receptor binding and animal pharmacology of meptazinol.
Topics: Analgesia; Animals; Azepines; Brain; Dogs; Meptazinol; Mice; Naloxone; Narcotics; Rats; Receptors, Opioid | 1985 |
The effects of meptazinol in comparison with pentazocine, morphine and naloxone in a rat model of anaphylactic shock.
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Decerebrate State; Electric Stimulation; Female; Heart Rate; Hemodynamics; Meptazinol; Morphine; Naloxone; Pentazocine; Phentolamine; Rats; Rats, Inbred Strains; Reserpine; Time Factors | 1985 |
Comparison of the cardiovascular effects of meptazinol and naloxone following haemorrhagic shock in rats and cats.
Topics: Anesthesia; Animals; Azepines; Cardiac Output; Cats; Female; Heart Rate; Hemodynamics; Meptazinol; Naloxone; Rats; Rats, Inbred Strains; Shock, Hemorrhagic; Species Specificity; Time Factors; Vascular Resistance | 1985 |
Evidence for functionally distinct mu receptors modulating acetylcholine release.
Topics: Acetylcholine; Animals; Corpus Striatum; In Vitro Techniques; Meptazinol; Morphine; Naloxone; Parietal Lobe; Potassium; Rats; Receptors, Opioid; Receptors, Opioid, mu | 1984 |
Endogenous opioid withdrawal in the Jarisch-Herxheimer reaction.
Topics: Anti-Bacterial Agents; Azepines; Body Temperature; Endorphins; Fever; Humans; Meptazinol; Models, Biological; Naloxone; Substance Withdrawal Syndrome; Syphilis | 1983 |
Meptazinol: a novel Mu-1 selective opioid analgesic.
Topics: Analgesia; Analgesics, Opioid; Animals; Azepines; Binding Sites; Male; Meptazinol; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Respiration; Tritium | 1984 |
Pharmacological effects of meptazinol and its enantiomers on guinea-pig ileum and mouse vas deferens.
Topics: Animals; Azepines; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Meptazinol; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotics; Stereoisomerism; Vas Deferens | 1984 |
The antinociceptive activity of meptazinol depends on both opiate and cholinergic mechanisms.
Topics: Analgesics; Animals; Azepines; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Meptazinol; Mice; Naloxone; Narcotics; Oxotremorine; Parasympathetic Nervous System; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
Meptazinol activity on morphine-naive and morphine-dependent guinea-pig ileum: correlation with in vivo studies.
Topics: Animals; Azepines; Benzomorphans; Drug Tolerance; Guinea Pigs; Humans; Ileum; Male; Meptazinol; Morphine Dependence; Muscle Contraction; Muscle, Smooth; Naloxone; Rats; Rats, Inbred Strains | 1984 |
Naloxone reversal of meptazinol-induced respiratory depression. An investigation of the effect of naloxone on meptazinol-induced respiratory depression in anaesthetised.
Topics: Adult; Anesthesia, General; Azepines; Carbon Dioxide; Depression, Chemical; Female; Humans; Male; Meptazinol; Middle Aged; Naloxone; Respiration; Tidal Volume | 1982 |
Chronic catheterization of the epidural space in rabbits: a model for behavioural and histopathological studies. Examination of meptazinol neurotoxicity.
Topics: Animals; Behavior, Animal; Catheterization; Drug Tolerance; Female; Injections, Epidural; Lidocaine; Lumbar Vertebrae; Meptazinol; Myelitis; Naloxone; Pain; Paralysis; Placebos; Polyradiculopathy; Rabbits; Sodium Chloride; Spinal Cord; Spinal Cord Diseases | 1993 |