meptazinol has been researched along with morphine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (75.00) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B | 1 |
| Goode, PG; Rhodes, KF; Waterfall, JF | 1 |
| Rashid, S; Waterfall, JF | 1 |
| Camu, F; Verborgh, C | 1 |
| Cordone, R; Estrada, N; Laska, E; Olson, NZ; Richman, H; Robissa, N; Siegel, C; Sunshine, A | 1 |
| Frater, RA; Hanning, CD; Moores, MA; Parry, P | 1 |
| Wali, FA | 1 |
| Cordone, R; Estrada, N; Olson, N; Richman, H; Robissa, N; Sunshine, A | 1 |
| Frater, R; Hanning, CD; Moores, MA; Parry, P | 1 |
| Nimmo, WS; Todd, JG; Vogel, J | 1 |
| Jasinski, DR; Johnson, RE | 1 |
| Houde, RW; Larouche Korn, SJ | 1 |
| Cowlrick, IS; Shepperson, NB | 1 |
| Paciorek, PM; Todd, MH; Waterfall, JF | 1 |
| Canel, A; Houde, RW; Jacobs, B; Kaiko, RF; Rogers, AG; Wallenstein, SL | 2 |
| Allen, MC; Baldwin, D; Bullingham, RE; Kay, NH; McQuay, RJ; Moore, HA; Price, RK; Sear, JW | 1 |
| Ennis, C; Wyllie, MG | 1 |
| Pasternak, GW; Spiegel, K | 1 |
| Gintzler, AR; Goodman, RR; Houghten, RA; Johnson, N; Ling, GS; Nishimura, S; Pasternak, GW; Recht, LD; Spiegel, K | 1 |
| Harmer, M; Rosen, M; Slattery, PJ; Vickers, MD | 1 |
| Clark, G; Cohen, DG; Coutinho, P; Jothilingham, S; Major, E | 1 |
| Jones, JG | 1 |
| Ennis, C; Stephens, RJ | 1 |
| Bensreti, MM; Gonzalez, JP; Sewell, RD | 1 |
| de Rosayro, M; Healy, TE; Morris, GK | 1 |
| Bruckmann, W; Friderichs, E; Tzschentke, TM | 1 |
| Chen, Y; Hao, JL; Li, W; Qiu, ZB; Tang, Y | 1 |
13 trial(s) available for meptazinol and morphine
| Article | Year |
|---|---|
Post-surgical pain relief with zero-order intravenous infusions of meptazinol and morphine: a double-blind placebo-controlled evaluation of their effects on ventilation.
Topics: Abdomen; Adult; Azepines; Blood Pressure; Carbon Dioxide; Double-Blind Method; Female; Heart Rate; Humans; Infusions, Intravenous; Male; Meptazinol; Middle Aged; Morphine; Pain, Postoperative; Randomized Controlled Trials as Topic; Respiration | 1990 |
Meptazinol and morphine in postoperative pain assessed with a new method for onset and duration.
Topics: Adult; Azepines; Double-Blind Method; Female; Humans; Male; Meptazinol; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Randomized Controlled Trials as Topic; Time Factors | 1989 |
Analgesia-induced respiratory depression: comparison of meptazinol and morphine in the postoperative period.
Topics: Aged; Aged, 80 and over; Azepines; Cyclizine; Depression, Chemical; Female; Hip Prosthesis; Humans; Male; Meptazinol; Middle Aged; Morphine; Pain, Postoperative; Respiration | 1989 |
Double-blind comparison of parenteral meptazinol and morphine in postoperative pain.
Topics: Azepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Meptazinol; Morphine; Pain, Postoperative; Random Allocation | 1987 |
Double-blind comparison of the efficacy and safety of single doses of meptazinol as a suppository and morphine by i.m. injection.
Topics: Administration, Rectal; Adult; Azepines; Double-Blind Method; Drug Evaluation; Female; Humans; Injections, Intramuscular; Meptazinol; Morphine; Pain, Postoperative | 1988 |
Effect of meptazinol on drug absorption and gastric emptying.
Topics: Acetaminophen; Administration, Oral; Azepines; Gastric Emptying; Humans; Intestinal Absorption; Meptazinol; Morphine; Premedication; Random Allocation | 1986 |
Human pharmacology and abuse potential of meptazinol.
Topics: Adult; Azepines; Double-Blind Method; Drug Evaluation; Euphoria; Humans; Male; Meptazinol; Morphine; Opioid-Related Disorders; Pupil; Random Allocation; Surveys and Questionnaires | 1987 |
Parenteral meptazinol: a US clinical trial.
Topics: Adolescent; Adult; Aged; Azepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Meptazinol; Middle Aged; Morphine; Pain, Postoperative; Time Factors | 1985 |
Intramuscular meptazinol and morphine in postoperative pain.
Topics: Adolescent; Adult; Aged; Azepines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Emotions; Female; Humans; Injections, Intramuscular; Male; Meptazinol; Middle Aged; Morphine; Pain, Postoperative; Random Allocation; Surveys and Questionnaires | 1985 |
Intramuscular on demand analgesia: double blind controlled trial of pethidine, buprenorphine, morphine, and meptazinol.
Topics: Adolescent; Adult; Aged; Analgesics; Buprenorphine; Cholecystectomy; Clinical Trials as Topic; Dizziness; Double-Blind Method; Female; Humans; Injections, Intramuscular; Male; Meperidine; Meptazinol; Middle Aged; Morphine; Pain, Postoperative | 1983 |
Meptazinol in the treatment of severe post-operative pain: a comparison with morphine.
Topics: Adolescent; Adult; Aged; Azepines; Blood Pressure; Bone and Bones; Carbon Dioxide; Double-Blind Method; Heart Rate; Humans; Meptazinol; Middle Aged; Morphine; Pain, Postoperative; Respiratory Function Tests; Time Factors | 1983 |
The respiratory effects of meptazinol.
Topics: Adult; Azepines; Carbon Dioxide; Humans; Male; Meptazinol; Morphine; Nausea; Respiration; Time Factors; Vomiting | 1983 |
Meptazinol and morphine compared: a study using systolic time intervals.
Topics: Adult; Aged; Azepines; Female; Humans; Male; Meptazinol; Middle Aged; Morphine; Myocardial Contraction; Systole; Time Factors | 1981 |
19 other study(ies) available for meptazinol and morphine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation | 2019 |
The analgesic and respiratory effects of meptazinol, morphine and pentazocine in the rat.
Topics: Analgesics; Animals; Azepines; Female; Hemodynamics; Meptazinol; Morphine; Pentazocine; Rats; Reaction Time; Respiration; Seizures; Time Factors | 1979 |
Cardiovascular actions of meptazinol in comparison with pentazocine and morphine.
Topics: Anesthesia; Animals; Atropine; Azepines; Blood Pressure; Cardiac Output; Cats; Electrocardiography; Female; Heart Rate; Hemodynamics; Hypertension; Male; Meptazinol; Morphine; Pentazocine; Rats | 1979 |
On the cholinergic component of action of meptazinol.
Topics: Acetylcholine; Animals; Azepines; Diaphragm; Dose-Response Relationship, Drug; Fentanyl; Ileum; Male; Meptazinol; Morphine; Muscle Contraction; Naloxone; Rats; Rats, Inbred Strains | 1986 |
The effects of a new opioid analgesic, meptazinol, on the respiration of the conscious rat.
Topics: Animals; Atropine; Azepines; Carbon Dioxide; Male; Meptazinol; Morphine; Narcotic Antagonists; Narcotics; Rats; Rats, Inbred Strains; Respiration; Stereoisomerism; Time Factors | 1985 |
The effects of meptazinol in comparison with pentazocine, morphine and naloxone in a rat model of anaphylactic shock.
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Decerebrate State; Electric Stimulation; Female; Heart Rate; Hemodynamics; Meptazinol; Morphine; Naloxone; Pentazocine; Phentolamine; Rats; Rats, Inbred Strains; Reserpine; Time Factors | 1985 |
Influence of meptazinol on metabolic and hormonal responses following major surgery. A comparison with morphine.
Topics: Adult; Azepines; Blood Glucose; Female; Growth Hormone; Humans; Hydrocortisone; Meptazinol; Morphine; Postoperative Complications; Prolactin; Stress, Physiological; Thyrotropin | 1985 |
Evaluation of intramuscular meptazinol and morphine in cancer patients with postoperative pain.
Topics: Azepines; Dose-Response Relationship, Drug; Injections, Intramuscular; Meptazinol; Morphine; Neoplasms; Palliative Care; Postoperative Care | 1984 |
Evidence for functionally distinct mu receptors modulating acetylcholine release.
Topics: Acetylcholine; Animals; Corpus Striatum; In Vitro Techniques; Meptazinol; Morphine; Naloxone; Parietal Lobe; Potassium; Rats; Receptors, Opioid; Receptors, Opioid, mu | 1984 |
Meptazinol: a novel Mu-1 selective opioid analgesic.
Topics: Analgesia; Analgesics, Opioid; Animals; Azepines; Binding Sites; Male; Meptazinol; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Respiration; Tritium | 1984 |
Biochemical and pharmacological evidence for opioid receptor multiplicity in the central nervous system.
Topics: Analgesia; Animals; beta-Endorphin; Brain; Endorphins; Enkephalins; Meptazinol; Morphine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration | 1983 |
A comparison of the effects of meptazinol and morphine on the release of acetylcholine from slices of mouse cerebral cortex.
Topics: Acetylcholine; Animals; Azepines; Cerebral Cortex; Female; Kinetics; Meptazinol; Mice; Morphine; Oxotremorine; Scopolamine; Tetrodotoxin | 1984 |
Meptazinol cross-tolerance studies between morphine or oxotremorine.
Topics: Animals; Azepines; Drug Tolerance; Male; Meptazinol; Mice; Morphine; Nociceptors; Oxotremorine | 1984 |
Lack of sensitization during place conditioning in rats is consistent with the low abuse potential of tramadol.
Topics: Animals; Behavior, Animal; Conditioning, Psychological; Male; Meptazinol; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Substance-Related Disorders; Tramadol | 2002 |
Structural comparisons of meptazinol with opioid analgesics.
Topics: Analgesics, Opioid; Meptazinol; Molecular Conformation; Molecular Structure; Morphine; Quantitative Structure-Activity Relationship; Stereoisomerism; Tramadol | 2005 |