mepivacaine and chlorpromazine

mepivacaine has been researched along with chlorpromazine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Butler, KW; Neal, MJ; Polnaszek, CF; Smith, IC1
Bohn, E; Kunze, H; Vogt, W1
Cooke, WJ; Rosenberg, FJ; Wessinger, GD1
Ciofalo, FR1
HEINONEN, J1

Reviews

1 review(s) available for mepivacaine and chlorpromazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for mepivacaine and chlorpromazine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
The influence of anesthetics and cholesterol on the degree of molecular organization and mobility of ox brain white matter. Lipids in multibilayer membranes: a spin probe study using spectral simulation by the stochastic method.
    Molecular pharmacology, 1976, Volume: 12, Issue:1

    Topics: Anesthetics; Animals; Brain; Brain Chemistry; Calcium; Cattle; Chlorpromazine; Cholesterol; Lipid Metabolism; Male; Mepivacaine; Pentobarbital; Promazine; Stearic Acids; Tetracaine

1976
Effects of local anaesthetics on prostaglandin biosynthesis in vitro.
    Biochimica et biophysica acta, 1974, Sep-19, Volume: 360, Issue:3

    Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Animals; Benzocaine; Calcium; Carbon Radioisotopes; Cattle; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Dibucaine; Edetic Acid; Kinetics; Lidocaine; Linoleic Acids; Male; Mepivacaine; Oleic Acids; Phosphatidylethanolamines; Phospholipases; Procaine; Prostaglandins; Seminal Vesicles; Sheep; Snakes; Species Specificity; Tetracaine; Triglycerides

1974
The effect of central nervous system depressants on the tolerance to local anesthetic solutions.
    International surgery, 1971, Volume: 55, Issue:2

    Topics: Anesthetics, Local; Animals; Barbiturates; Chlorpromazine; Drug Synergism; Lidocaine; Male; Meperidine; Mepivacaine; Mice; Preanesthetic Medication; Promethazine; Seizures

1971
Effects of some membrane perturbers on alpha 1-adrenergic receptor binding.
    Neuroscience letters, 1981, Feb-06, Volume: 21, Issue:3

    Topics: Animals; Cattle; Cerebral Cortex; Chlorpromazine; Dibucaine; Dioxanes; Lidocaine; Membranes; Mepivacaine; Phenytoin; Procainamide; Procaine; Propranolol; Quinidine; Receptors, Adrenergic; Receptors, Adrenergic, alpha

1981
THE EFFECT OF DRUGS ON THE DURATION OF TOXIC SYMPTOMS CAUSED BY SUBLETHAL DOSES OF LOCAL ANESTHETICS. AN EXPERIMENTAL STUDY ON MICE.
    Acta pharmacologica et toxicologica, 1964, Volume: 21

    Topics: Anesthetics; Anesthetics, Local; Barbiturates; Bemegride; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Ethionine; Iproniazid; Isoniazid; Lidocaine; Mepivacaine; Meprobamate; Mice; Nikethamide; Pentobarbital; Pharmacology; Phenobarbital; Research; Toxicology

1964