Page last updated: 2024-08-18

mephobarbital and primidone

mephobarbital has been researched along with primidone in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (78.05)	18.7374
1990's	2 (4.88)	18.2507
2000's	3 (7.32)	29.6817
2010's	4 (9.76)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Eadie, MJ; Lander, CM; Tyrer, JH	1
Buchthal, A	1
Hanson, JW; Smith, DW	1
Hebenstreit, G; Lechner, H	1
Burke, DG; Halpern, B; Korth, J; Summons, R; Truscott, RJ	1
Eadie, MJ; Hooper, WD; Lander, CM; Tyrer, JH	1
Jeremić, V; Nikolić, R	1
Friel, P; Troupin, AS	1
Blaskovics, ME; Podosin, RL; Roe, TF	1
Wehrhahn, L; Wiegrebe, W	1
Annegers, JF; Elveback, LR; Hauser, WA; Kurland, LT	2
Eadie, MJ	1
Kar, PP; Matin, MA	1
Brill, PW; Leonidas, JC; Waldman, N	1
Mitterstieler, G; Schwingshackl, A; Waltl, H	1
Freeman, JM; Lietman, PS	1
Saad, SF	1
Gardner-Thorpe, C; Parsonage, MJ; Toothill, C	1
Garrettson, LK	1
Rodgers, G; Roger, JC; Soo, A	1
Lifshitz, F; Maclaren, NK	1
Cremers, HM; Verheesen, PE	1
Hill, RM; Horning, MG; McCulley, LB; Morgan, NF; Verniaud, WM	1
Booker, HE; Chun, RW; Sanguino, M	1
Borgstedt, AD; Bryson, MF; Forbes, GB; Young, LW	1
Spilker, B; Yeager, CL	1
Holliday, TA	1
Jaffery, FN; Matin, MA; Siddiqui, RA	1
Hayes, SG	1
Alkhamis, KA; Wurster, DE	1
LIVINGSTON, S	1
JONES, JD; MILLICHAP, JG; RUDIS, BP	1
DEVOTO, RA; PODESTA, LD; PRECERUTTI, AS	1
Alkhamis, KA; Matheson, LE; Wurster, DE	1
Bialer, M	1

Reviews

6 review(s) available for mephobarbital and primidone

Article	Year
[Pharmacotherapy of epilepsy. II]. Die Medizinische Welt, 1978, Jun-02, Volume: 29, Issue:22 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid	1978
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance. Clinical pharmacokinetics, 1991, Volume: 21, Issue:1 Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid	1991
A basic approach to the understanding of seizures and the mechanism of action and metabolism of anticonvulsants. Advances in pediatrics, 1973, Volume: 20, Issue:0 Topics: Acetylcholine; Aminobutyrates; Anticonvulsants; Calcium; Cell Membrane Permeability; Depression, Chemical; Diazepam; Epilepsy; Ethosuximide; Humans; Membrane Potentials; Mephobarbital; Neural Inhibition; Neurons; Phenobarbital; Phenytoin; Primidone; Seizures; Stimulation, Chemical; Synapses; Synaptic Transmission	1973
Pharmacology of anticonvulsants. Pediatric clinics of North America, 1972, Volume: 19, Issue:1 Topics: Animals; Anticonvulsants; Child; Drug Interactions; Electroencephalography; Ethosuximide; Half-Life; Humans; Liver; Mephobarbital; Phenobarbital; Phenytoin; Primidone	1972
Seizure disorders. The Veterinary clinics of North America. Small animal practice, 1980, Volume: 10, Issue:1 Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Dog Diseases; Dogs; Epilepsy; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Recurrence; Seizures; Succinimides	1980
Barbiturate anticonvulsants in refractory affective disorders. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1993, Volume: 5, Issue:1 Topics: Adult; Anticonvulsants; Barbiturates; Bipolar Disorder; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Mephobarbital; Primidone; Psychiatric Status Rating Scales; Psychotic Disorders; Severity of Illness Index; Sex Factors; Treatment Outcome	1993

Trials

1 trial(s) available for mephobarbital and primidone

Article	Year
Barbiturate anticonvulsants in refractory affective disorders. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1993, Volume: 5, Issue:1 Topics: Adult; Anticonvulsants; Barbiturates; Bipolar Disorder; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Mephobarbital; Primidone; Psychiatric Status Rating Scales; Psychotic Disorders; Severity of Illness Index; Sex Factors; Treatment Outcome	1993

Article

Year

Barbiturate anticonvulsants in refractory affective disorders.

Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1993, Volume: 5, Issue:1

Topics: Adult; Anticonvulsants; Barbiturates; Bipolar Disorder; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Mephobarbital; Primidone; Psychiatric Status Rating Scales; Psychotic Disorders; Severity of Illness Index; Sex Factors; Treatment Outcome

1993

Other Studies

35 other study(ies) available for mephobarbital and primidone

Article	Year
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship	2003
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Interactions between anticonvulsants. Proceedings of the Australian Association of Neurologists, 1975, Volume: 12 Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Humans; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Thiazines	1975
The fetal hydantoin syndrome. The Journal of pediatrics, 1975, Volume: 87, Issue:2 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Child, Preschool; Developmental Disabilities; Epilepsy; Female; Fetus; Fingers; Growth Disorders; Humans; Hydantoins; Hypertelorism; Infant; Intellectual Disability; Male; Mephobarbital; Motor Skills; Mouth Abnormalities; Myoclonus; Nails, Malformed; Phenobarbital; Pregnancy; Pregnancy Complications; Primidone; Succinimides; Syndrome; Teratogens; Toes	1975
[Drug therapy of epilepsy]. Wiener medizinische Wochenschrift (1946), 1975, May-30, Volume: 125, Issue:22-24 Topics: Anticonvulsants; Carbamazepine; Chlordiazepoxide; Clonazepam; Diazepam; Electroencephalography; Epilepsy; Humans; Hydantoins; Mephobarbital; Nitrazepam; Primidone; Succinimides; Thiazines; Time Factors	1975
Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry. Biomedical mass spectrometry, 1978, Volume: 5, Issue:8 Topics: Anticonvulsants; Carbamazepine; Computers; Evaluation Studies as Topic; Humans; Mass Spectrometry; Mephobarbital; Methods; Palmitic Acids; Phenobarbital; Phenytoin; Primidone	1978
Factors influencing plasma phenobarbitone levels in epileptic patients. British journal of clinical pharmacology, 1977, Volume: 4, Issue:5 Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Mephobarbital; Middle Aged; Phenobarbital; Primidone; Sex Factors	1977
An improved UV-spectrophotometric method for routine barbiturate monitoring. Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1976, Volume: 14, Issue:10 Topics: Humans; Mephobarbital; Phenobarbital; Primidone; Spectrophotometry, Ultraviolet	1976
Flash-heater ethylation of some antiepileptic drugs. Clinical chemistry, 1975, Volume: 21, Issue:6 Topics: Alkylation; Anticonvulsants; Evaluation Studies as Topic; Hot Temperature; Humans; Mephenytoin; Mephobarbital; Methylation; Phenobarbital; Phenytoin; Primidone; Saliva	1975
Drug interaction: diazoxide and diphenylhydantoin. The Journal of pediatrics, 1975, Volume: 87, Issue:3 Topics: Administration, Oral; Adolescent; Child, Preschool; Chromatography, Gas; Diazoxide; Drug Therapy, Combination; Ethosuximide; Humans; Hyperinsulinism; Hypoglycemia; Infant; Injections, Intramuscular; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Radioligand Assay; Seizures	1975
[Polarographic determination of some phenylsubstituted anticonvulsants]. Arzneimittel-Forschung, 1975, Volume: 25, Issue:4 Topics: Anticonvulsants; Chromatography, Thin Layer; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Polarography; Primidone	1975
Epilepsy anticonvulsants and malformations. Birth defects original article series, 1975, Volume: 11, Issue:5 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defects, Congenital; Humans; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Teratogens	1975
Effect of barbiturates and isoniazid on cerebral hemisphere gamma-aminobutyric acid content in pp' DDT treated mice. Pharmacological research communications, 1974, Volume: 6, Issue:4 Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Behavior, Animal; Brain Chemistry; DDT; Drug Synergism; gamma-Aminobutyric Acid; Isoniazid; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Seizures	1974
Antiepileptic therapy and rickets in children. Radiology, 1973, Volume: 109, Issue:2 Topics: Adolescent; Anticonvulsants; Barbiturates; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Rickets	1973
[Haemorrhagic diathesis in a newborn child of a mother on anti-epileptic medication (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1974, Jun-14, Volume: 99, Issue:24 Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Hemostatics; Humans; Infant, Newborn; Maternal-Fetal Exchange; Mephobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Shock, Hemorrhagic; Vitamin K Deficiency Bleeding	1974
The effect of isoniazid and some anticonvulsant drugs on the gamma-aminobutyric acid content of mouse brain in insulin hypoglycaemia. The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:5 Topics: Aminobutyrates; Animals; Barbiturates; Brain; Brain Chemistry; Cerebral Cortex; Hypoglycemia; Insulin Antagonists; Isoniazid; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Seizures	1970
Anticonvulsant drugs in idiopathic epilepsy. The Medical letter on drugs and therapeutics, 1970, Jun-26, Volume: 12, Issue:13 Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome; Succinimides; Urea	1970
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography. Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 35, Issue:1 Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines	1971
Do anticonvulsants have a teratogenic effect? Archives of neurology, 1974, Volume: 31, Issue:6 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital Abnormalities; Epilepsy; Female; Heart Defects, Congenital; Humans; Infant; Infant Mortality; Infant, Newborn; Intellectual Disability; Male; Mephobarbital; Minnesota; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Primidone; Teratogens	1974
Simultaneous determination of carbamazapine ("Tegretol") and other anticonvulsants in human plasma by gas-liquid chromatography. Clinical chemistry, 1973, Volume: 19, Issue:6 Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Computers; Dibenzazepines; Humans; Hydantoins; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds	1973
Vitamin D-dependent rickets in institutionalized, mentally retarded children receiving long-term anticonvulsant therapy. I. A survey of 288 patients. The Journal of pediatrics, 1973, Volume: 83, Issue:4 Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Magnesium; Male; Mephobarbital; Mesoridazine; Phenobarbital; Phenytoin; Phosphorus; Potassium; Primidone; Rickets; Seizures; Sodium; Succinimides; Vitamin D	1973
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography. Clinica chimica acta; international journal of clinical chemistry, 1973, Nov-15, Volume: 48, Issue:4 Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Humans; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides; Temperature; Time Factors; Trimethadione	1973
Infants exposed in utero to antiepileptic drugs. A prospective study. American journal of diseases of children (1960), 1974, Volume: 127, Issue:5 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chromatography, Gas; Diazepam; Epilepsy; Ethosuximide; Female; Fetus; Growth Disorders; Humans; Hydantoins; Infant, Newborn; Mass Spectrometry; Mephobarbital; Meprobamate; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Prochlorperazine; Prospective Studies; Substance Withdrawal Syndrome; Succinimides; Time Factors	1974
Myasthenia gravis syndrome associated with trimethadione. JAMA, 1970, Jun-29, Volume: 212, Issue:13 Topics: Anticonvulsants; Autoimmune Diseases; Child; Drug Hypersensitivity; Epilepsy, Absence; Female; Humans; Mephobarbital; Myasthenia Gravis; Neostigmine; Oxazoles; Primidone; Trimethadione	1970
Long-term administration of antiepileptic drugs and the development of rickets. The Journal of pediatrics, 1972, Volume: 81, Issue:1 Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Diazepam; Ethosuximide; Female; Gluconates; Humans; Infant; Mephobarbital; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Radiography; Rickets; Seizures; Time Factors; Trimethadione; Vitamin D	1972
Ten years EEG studies in epileptic children (two cases). Diseases of the nervous system, 1969, Volume: 30, Issue:3 Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Emotions; Epilepsy; Humans; Mephobarbital; Phenytoin; Primidone; Trimethadione	1969
A possible neurochemical basis of the central stimulatory effects of pp'DDT. Journal of neurochemistry, 1981, Volume: 36, Issue:3 Topics: Acetylcholine; Aminooxyacetic Acid; Ammonia; Animals; Central Nervous System; Corpus Striatum; DDT; gamma-Aminobutyric Acid; Hydroxylamines; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Pyridoxine; Seizures	1981
Prediction of adsorption from multicomponent solutions by activated carbon using single-solute parameters. Part II--Proposed equation. AAPS PharmSciTech, 2002, Volume: 3, Issue:3 Topics: Adsorption; Body Fluids; Charcoal; Chromatography, High Pressure Liquid; Gastrointestinal Contents; Mephobarbital; Models, Chemical; Pancreatin; Phenobarbital; Predictive Value of Tests; Primidone; Solutions; Thermodynamics	2002
ANTIEPILEPTIC DRUGS. The American journal of nursing, 1963, Volume: 63 Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Barbiturates; Bromides; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Meprobamate; Phenobarbital; Phenytoin; Primidone; Succinimides; Toxicology	1963
MECHANISM OF ANTICONVULSANT ACTION OF KETOGENIC DIET. STUDIES IN ANIMALS WITH EXPERIMENTAL SEIZURES AND IN CHILDREN WITH PETIT MAL EPILEPSY. American journal of diseases of children (1960), 1964, Volume: 107 Topics: Acetazolamide; Acid-Base Equilibrium; Acidosis; Adolescent; Anticonvulsants; Barbiturates; Biomedical Research; Blood Gas Analysis; Child; Diet Therapy; Diet, Ketogenic; Dietary Fats; Electric Stimulation; Electrophysiology; Epilepsy; Epilepsy, Absence; Humans; Mephobarbital; Mice; Primidone; Research; Seizures; Succinimides	1964
[MEGALOBLASTIC ANEMIA PRODUCED BY ANTICONVULSANTS]. Prensa medica argentina, 1963, Oct-25, Volume: 50 Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Argentina; Barbiturates; Blood Cell Count; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Mephobarbital; Phenytoin; Primidone; Splenomegaly; Toxicology	1963
Prediction of adsorption from multicomponent solutions by activated carbon using single-solute parameters. AAPS PharmSciTech, 2000, Aug-31, Volume: 1, Issue:3 Topics: Adsorption; Area Under Curve; Body Fluids; Charcoal; Gastrointestinal Contents; Mephobarbital; Models, Chemical; Molecular Structure; Phenobarbital; Predictive Value of Tests; Primidone; Solutions; Surface Properties	2000
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)? Epilepsia, 2012, Volume: 53 Suppl 8 Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid	2012