Page last updated: 2024-08-18

mephobarbital and phenytoin

mephobarbital has been researched along with phenytoin in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	44 (83.02)	18.7374
1990's	2 (3.77)	18.2507
2000's	3 (5.66)	29.6817
2010's	4 (7.55)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Eadie, MJ; Lander, CM; Tyrer, JH	2
Buchthal, A	1
Hattori, M; Kazamatsuri, H	1
Leuschner, U; Quednow, B; Walther, H	1
Burke, DG; Halpern, B; Korth, J; Summons, R; Truscott, RJ	1
Mallette, LE	1
Anderson, RC	1
Friel, P; Troupin, AS	1
Blaskovics, ME; Podosin, RL; Roe, TF	1
Wehrhahn, L; Wiegrebe, W	1
Annegers, JF; Elveback, LR; Hauser, WA; Kurland, LT	2
Eto, S; Noda, A; Noda, H	1
Eadie, MJ	1
Furlan, G; Mamolo, MG; Vio, L	1
Bale, P; Lipson, A	1
Bauer, G	1
Deitrich, RA; Erwin, VG	1
Brill, PW; Leonidas, JC; Waldman, N	1
Mitterstieler, G; Schwingshackl, A; Waltl, H	1
Diliberto, JJ	1
Freeman, JM; Lietman, PS	1
Gardner-Thorpe, C; Parsonage, MJ; Toothill, C	1
Garrettson, LK	1
Tharp, BR	1
Bärmig, H	1
Rodgers, G; Roger, JC; Soo, A	1
Lifshitz, F; Maclaren, NK	1
Cremers, HM; Verheesen, PE	1
Hill, RM; Horning, MG; McCulley, LB; Morgan, NF; Verniaud, WM	1
Borgstedt, AD; Bryson, MF; Forbes, GB; Young, LW	1
Spilker, B; Yeager, CL	1
Ito, K; Murata, T; Nioka, M; Owada, E; Sato, J	1
Holliday, TA	1
Bararay, M; Wahbi, AM	1
Luco, JM; Olsina, RA	1
El-Gindy, A; Emara, S; Hadad, GM	1
KOHLHEPP, B	1
WESTERINK, D	1
LIVINGSTON, S	1
JABBOUR, JT	1
DEVOTO, RA; PODESTA, LD; PRECERUTTI, AS	1
OLIVEROS, RG	1
SELIGER, H	1
GELLER, W	1
Bialer, M	1

Reviews

6 review(s) available for mephobarbital and phenytoin

Article	Year
[Pharmacotherapy of epilepsy. II]. Die Medizinische Welt, 1978, Jun-02, Volume: 29, Issue:22 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid	1978
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance. Clinical pharmacokinetics, 1991, Volume: 21, Issue:1 Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid	1991
A basic approach to the understanding of seizures and the mechanism of action and metabolism of anticonvulsants. Advances in pediatrics, 1973, Volume: 20, Issue:0 Topics: Acetylcholine; Aminobutyrates; Anticonvulsants; Calcium; Cell Membrane Permeability; Depression, Chemical; Diazepam; Epilepsy; Ethosuximide; Humans; Membrane Potentials; Mephobarbital; Neural Inhibition; Neurons; Phenobarbital; Phenytoin; Primidone; Seizures; Stimulation, Chemical; Synapses; Synaptic Transmission	1973
Pharmacology of anticonvulsants. Pediatric clinics of North America, 1972, Volume: 19, Issue:1 Topics: Animals; Anticonvulsants; Child; Drug Interactions; Electroencephalography; Ethosuximide; Half-Life; Humans; Liver; Mephobarbital; Phenobarbital; Phenytoin; Primidone	1972
Recent progress in epilepsy. Diagnostic procedures and treatment. California medicine, 1973, Volume: 119, Issue:1 Topics: Anticonvulsants; Brain Neoplasms; Diazepam; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Humans; Mephobarbital; Phenobarbital; Phenytoin; Psychosurgery; United States	1973
Seizure disorders. The Veterinary clinics of North America. Small animal practice, 1980, Volume: 10, Issue:1 Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Dog Diseases; Dogs; Epilepsy; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Recurrence; Seizures; Succinimides	1980

Other Studies

47 other study(ies) available for mephobarbital and phenytoin

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship	2003
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Interactions between anticonvulsants. Proceedings of the Australian Association of Neurologists, 1975, Volume: 12 Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Humans; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Thiazines	1975
Serum levels of phenytoin and phenobarbital in epileptic patients treated with mixture antiepileptic tablets, Comital-L or Hydantol-F. Folia psychiatrica et neurologica japonica, 1979, Volume: 33, Issue:3 Topics: Anticonvulsants; Drug Combinations; Epilepsy; Humans; Mephobarbital; Phenobarbital; Phenytoin	1979
[Studies on the separation and photometric determination of antiepileptics (author's transl)]. Die Pharmazie, 1979, Volume: 34, Issue:11 Topics: Anticonvulsants; Carbamazepine; Chromatography, Thin Layer; Humans; Mephobarbital; Methods; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet	1979
Factors influencing plasma carbamazepine concentrations. Clinical and experimental neurology, 1977, Volume: 14 Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Male; Mephobarbital; Middle Aged; Phenobarbital; Phenytoin	1977
Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry. Biomedical mass spectrometry, 1978, Volume: 5, Issue:8 Topics: Anticonvulsants; Carbamazepine; Computers; Evaluation Studies as Topic; Humans; Mass Spectrometry; Mephobarbital; Methods; Palmitic Acids; Phenobarbital; Phenytoin; Primidone	1978
Acetazolamide-accelerated anticonvulsant osteomalacia. Archives of internal medicine, 1977, Volume: 137, Issue:8 Topics: Acetazolamide; Adult; Anticonvulsants; Calcium; Epilepsy; Female; Humans; Mephobarbital; Osteomalacia; Phenobarbital; Phenytoin; Phosphates	1977
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy. The Journal of pediatrics, 1976, Volume: 89, Issue:2 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadione; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione	1976
Flash-heater ethylation of some antiepileptic drugs. Clinical chemistry, 1975, Volume: 21, Issue:6 Topics: Alkylation; Anticonvulsants; Evaluation Studies as Topic; Hot Temperature; Humans; Mephenytoin; Mephobarbital; Methylation; Phenobarbital; Phenytoin; Primidone; Saliva	1975
Drug interaction: diazoxide and diphenylhydantoin. The Journal of pediatrics, 1975, Volume: 87, Issue:3 Topics: Administration, Oral; Adolescent; Child, Preschool; Chromatography, Gas; Diazoxide; Drug Therapy, Combination; Ethosuximide; Humans; Hyperinsulinism; Hypoglycemia; Infant; Injections, Intramuscular; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Radioligand Assay; Seizures	1975
[Polarographic determination of some phenylsubstituted anticonvulsants]. Arzneimittel-Forschung, 1975, Volume: 25, Issue:4 Topics: Anticonvulsants; Chromatography, Thin Layer; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Polarography; Primidone	1975
Epilepsy anticonvulsants and malformations. Birth defects original article series, 1975, Volume: 11, Issue:5 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defects, Congenital; Humans; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Teratogens	1975
Chiral separation of barbiturates and hydantoins by reversed-phase high-performance liquid chromatography using a 25 or 50 mm short ODS cartridge column via beta-cyclodextrin inclusion complexes. Journal of chromatography, 1992, Sep-02, Volume: 579, Issue:2 Topics: Barbiturates; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Cyclodextrins; Humans; Hydantoins; Mephobarbital; Phenytoin; Stereoisomerism	1992
Simultaneous determination of phenobarbital, phenytoin and methylphenobarbital in tablet formulations by HPLC. Il Farmaco; edizione pratica, 1988, Volume: 43, Issue:5 Topics: Chromatography, High Pressure Liquid; Mephobarbital; Phenobarbital; Phenytoin; Tablets	1988
Ependymoblastoma associated with prenatal exposure to diphenylhydantoin and methylphenobarbitone. Cancer, 1985, May-01, Volume: 55, Issue:9 Topics: Brain Neoplasms; Child, Preschool; Ependymoma; Female; Frontal Lobe; Heterozygote; Humans; Maternal-Fetal Exchange; Mephobarbital; Ornithine Carbamoyltransferase Deficiency Disease; Phenytoin; Pregnancy	1985
[Addiction-like provocation of psychomotor seizures by daydreams]. Der Nervenarzt, 1973, Volume: 44, Issue:8 Topics: Adult; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Fantasy; Humans; Male; Mephobarbital; Phenytoin; Thiazines	1973
Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro. Biochemical pharmacology, 1973, Oct-15, Volume: 22, Issue:20 Topics: Aldehyde Oxidoreductases; Amobarbital; Animals; Anticonvulsants; Barbiturates; Brain; Cattle; Ethosuximide; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isomerism; Kinetics; Mephobarbital; NADP; Pentobarbital; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Trimethadione	1973
Antiepileptic therapy and rickets in children. Radiology, 1973, Volume: 109, Issue:2 Topics: Adolescent; Anticonvulsants; Barbiturates; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Rickets	1973
[Haemorrhagic diathesis in a newborn child of a mother on anti-epileptic medication (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1974, Jun-14, Volume: 99, Issue:24 Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Hemostatics; Humans; Infant, Newborn; Maternal-Fetal Exchange; Mephobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Shock, Hemorrhagic; Vitamin K Deficiency Bleeding	1974
Application of magnesium silicate adsorption chromatography to the determination of mephobarbital and diphenylhydantoin in tablets. Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:6 Topics: Barbiturates; Chromatography; Magnesium; Mephobarbital; Phenytoin; Silicon Dioxide; Spectrophotometry; Tablets; Ultraviolet Rays	1969
Anticonvulsant drugs in idiopathic epilepsy. The Medical letter on drugs and therapeutics, 1970, Jun-26, Volume: 12, Issue:13 Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome; Succinimides; Urea	1970
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography. Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 35, Issue:1 Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines	1971
Do anticonvulsants have a teratogenic effect? Archives of neurology, 1974, Volume: 31, Issue:6 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital Abnormalities; Epilepsy; Female; Heart Defects, Congenital; Humans; Infant; Infant Mortality; Infant, Newborn; Intellectual Disability; Male; Mephobarbital; Minnesota; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Primidone; Teratogens	1974
[Epilepsy and pregnancy]. Geburtshilfe und Frauenheilkunde, 1973, Volume: 33, Issue:3 Topics: Abortion, Spontaneous; Anticonvulsants; Birth Weight; Epilepsy; Female; Humans; Infant, Newborn; Infant, Premature; Intestinal Atresia; Mephobarbital; Phenytoin; Pregnancy; Pregnancy Complications	1973
Simultaneous determination of carbamazapine ("Tegretol") and other anticonvulsants in human plasma by gas-liquid chromatography. Clinical chemistry, 1973, Volume: 19, Issue:6 Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Computers; Dibenzazepines; Humans; Hydantoins; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds	1973
Vitamin D-dependent rickets in institutionalized, mentally retarded children receiving long-term anticonvulsant therapy. I. A survey of 288 patients. The Journal of pediatrics, 1973, Volume: 83, Issue:4 Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Magnesium; Male; Mephobarbital; Mesoridazine; Phenobarbital; Phenytoin; Phosphorus; Potassium; Primidone; Rickets; Seizures; Sodium; Succinimides; Vitamin D	1973
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography. Clinica chimica acta; international journal of clinical chemistry, 1973, Nov-15, Volume: 48, Issue:4 Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Humans; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides; Temperature; Time Factors; Trimethadione	1973
Infants exposed in utero to antiepileptic drugs. A prospective study. American journal of diseases of children (1960), 1974, Volume: 127, Issue:5 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chromatography, Gas; Diazepam; Epilepsy; Ethosuximide; Female; Fetus; Growth Disorders; Humans; Hydantoins; Infant, Newborn; Mass Spectrometry; Mephobarbital; Meprobamate; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Prochlorperazine; Prospective Studies; Substance Withdrawal Syndrome; Succinimides; Time Factors	1974
Long-term administration of antiepileptic drugs and the development of rickets. The Journal of pediatrics, 1972, Volume: 81, Issue:1 Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Diazepam; Ethosuximide; Female; Gluconates; Humans; Infant; Mephobarbital; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Radiography; Rickets; Seizures; Time Factors; Trimethadione; Vitamin D	1972
Ten years EEG studies in epileptic children (two cases). Diseases of the nervous system, 1969, Volume: 30, Issue:3 Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Emotions; Epilepsy; Humans; Mephobarbital; Phenytoin; Primidone; Trimethadione	1969
Effect of acetazolamide on the anticonvulsant potency of several antiepileptic drugs in mice. Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:5 Topics: Acetazolamide; Animals; Anticonvulsants; Barbital; Barbiturates; Brain; Drug Interactions; Male; Mephobarbital; Mice; Phenytoin; Time Factors; Trimethadione; Valproic Acid	1983
Spectrophotometric determination of phenobarbitone, methylphenobarbitone and phenytoin in tablets. The Analyst, 1980, Volume: 105, Issue:1254 Topics: Mephobarbital; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Tablets	1980
Simultaneous spectrophotometric determination of phenobarbital, phenytoin and methylphenobarbital in pharmaceutical preparations by using partial least-squares and principal component regression multivariate calibration. Journal of pharmaceutical and biomedical analysis, 2000, Dec-15, Volume: 24, Issue:2 Topics: Least-Squares Analysis; Mephobarbital; Multivariate Analysis; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet	2000
Determination of two ternary mixtures containing phenobarbitone by second derivative of the ratio spectrum-zero-crossing and HPLC methods. Farmaco (Societa chimica italiana : 1989), 2003, Volume: 58, Issue:5 Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Mephobarbital; Papaverine; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Theophylline	2003
[Experiences with comital and comital-L]. Medizinische Monatsschrift, 1951, Volume: 5, Issue:12 Topics: Barbiturates; Drug Combinations; Epilepsy; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin	1951
[Chromatographic separation and microdetermination of phenobarbital, methylphenobarbital, butobarbital and phenytoin]. Pharmaceutisch weekblad, 1962, Nov-09, Volume: 97 Topics: Barbiturates; Chromatography; Mephobarbital; Phenobarbital; Phenytoin	1962
ANTIEPILEPTIC DRUGS. The American journal of nursing, 1963, Volume: 63 Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Barbiturates; Bromides; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Meprobamate; Phenobarbital; Phenytoin; Primidone; Succinimides; Toxicology	1963
THE INFANT WITH EPILEPSY. Southwestern medicine, 1963, Volume: 44 Topics: Acetazolamide; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Birth Injuries; Classification; Diagnosis; Epilepsy; Epilepsy, Temporal Lobe; Female; Genetics, Medical; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Mephobarbital; Meprobamate; Metabolism; Myoclonus; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Seizures; Spasms, Infantile; Temporal Lobe; Toxicology; Wounds and Injuries	1963
[MEGALOBLASTIC ANEMIA PRODUCED BY ANTICONVULSANTS]. Prensa medica argentina, 1963, Oct-25, Volume: 50 Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Argentina; Barbiturates; Blood Cell Count; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Mephobarbital; Phenytoin; Primidone; Splenomegaly; Toxicology	1963
[REHABILITATION OF THE EPILEPTIC. CLINICAL EXPERIENCE WITH A POTENTIALIZED ANTICONVULSANT]. Hospital (Rio de Janeiro, Brazil), 1964, Volume: 65 Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Mephobarbital; Phenobarbital; Phenytoin	1964
[Results of recent study on the combination of barbituric acid derivatives, prominal and luminal with sodium diphenylhydantoinate, and its effect in clinical use]. Arztliche Wochenschrift, 1950, Nov-10, Volume: 5, Issue:44 Topics: Barbital; Barbiturates; Hydantoins; Mephobarbital; Phenytoin	1950
[Combined diphenylhydantoin and prominal therapy of cerebral spasms]. Der Nervenarzt, 1950, Volume: 21, Issue:3 Topics: Anticonvulsants; Barbital; Hydantoins; Mephobarbital; Phenytoin; Spasm	1950
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)? Epilepsia, 2012, Volume: 53 Suppl 8 Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid	2012