mephobarbital has been researched along with mephenytoin in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Buchthal, A | 1 |
| Friel, P; Troupin, AS | 1 |
| Wehrhahn, L; Wiegrebe, W | 1 |
| Eadie, MJ | 1 |
| Inaba, T | 1 |
| Branch, RA; Hall, SD; Jacqz, E; Wilkinson, GR | 1 |
| Branch, RA; Küpfer, A | 1 |
| Helsby, NA; Ward, SA; Wright, JD | 1 |
| Bialer, M | 1 |
3 review(s) available for mephobarbital and mephenytoin
| Article | Year |
|---|---|
[Pharmacotherapy of epilepsy. II].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid | 1978 |
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance.
Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid | 1991 |
Genetic polymorphism of mephenytoin metabolism.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemical Phenomena; Chemistry; China; Cytochrome P-450 CYP2C19; Debrisoquin; Dogs; Ethnicity; Humans; Hydantoins; Hydroxylation; Japan; Kinetics; Liver; Mephenytoin; Mephobarbital; Mice; Mixed Function Oxygenases; Ontario; Phenotype; Polymorphism, Genetic; Sparteine; Tennessee; White People | 1986 |
8 other study(ies) available for mephobarbital and mephenytoin
| Article | Year |
|---|---|
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Flash-heater ethylation of some antiepileptic drugs.
Topics: Alkylation; Anticonvulsants; Evaluation Studies as Topic; Hot Temperature; Humans; Mephenytoin; Mephobarbital; Methylation; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
[Polarographic determination of some phenylsubstituted anticonvulsants].
Topics: Anticonvulsants; Chromatography, Thin Layer; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Polarography; Primidone | 1975 |
Polymorphic metabolism of mephenytoin in man: pharmacokinetic interaction with a co-regulated substrate, mephobarbital.
Topics: Administration, Oral; Adult; Aged; Drug Interactions; Female; Humans; Hydantoins; Kinetics; Male; Mephenytoin; Mephobarbital; Metabolic Clearance Rate; Middle Aged; Phenotype; Polymorphism, Genetic; Stereoisomerism | 1986 |
Stereoselective mephobarbital hydroxylation cosegregates with mephenytoin hydroxylation.
Topics: Administration, Oral; Chromatography, High Pressure Liquid; Humans; Hydantoins; Hydroxylation; Mephenytoin; Mephobarbital; Phenotype; Stereoisomerism | 1985 |
The role of S-mephenytoin hydroxylase (CYP2C19) in the metabolism of the antimalarial biguanides.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Mephenytoin; Mephobarbital; Microsomes, Liver; Mixed Function Oxygenases; Proguanil; Substrate Specificity; Succinimides | 1995 |
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid | 2012 |