mephenytoin has been researched along with troleandomycin in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Horsmans, Y; Lannes, D; Larrey, D; Letteron, P; Loeper, J; Pessayre, D; Tinel, M | 1 |
| Chiba, K; Echizen, H; Ishizaki, T; Tani, M; Yoshimoto, K | 1 |
| Heyn, H; Stevens, JC; White, RB | 1 |
| Huang, SL; Ou-Yang, DS; Wu, ZL; Xie, HG; Xu, ZH; Zhou, HH | 1 |
| He, N; Huang, SL; Shu, Y; Wang, LS; Wang, W; Xiao, WM; Xu, ZH; Zhou, HH | 1 |
7 other study(ies) available for mephenytoin and troleandomycin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Nilutamide inhibits mephenytoin 4-hydroxylation in untreated male rats and in human liver microsomes.
Topics: Androgen Antagonists; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Female; Ferricyanides; Humans; Hydroxylation; Imidazoles; Imidazolidines; Male; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Troleandomycin | 1991 |
Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
Topics: Aged; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Ditiocarb; Female; Humans; Hydroxylation; In Vitro Techniques; Isoenzymes; Male; Mephenytoin; Microsomes, Liver; Middle Aged; Oxazines; Phenacetin; Propranolol; Quinidine; Recombinant Proteins; Stereoisomerism; Substrate Specificity; Sulfaphenazole; Tolbutamide; Troleandomycin | 1995 |
Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
Topics: Antibodies, Monoclonal; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Recombinant Proteins; Troleandomycin | 1996 |
Clomipramine N-demethylation metabolism in human liver microsomes.
Topics: Adult; Clomipramine; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; In Vitro Techniques; Mephenytoin; Methylation; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Theophylline; Troleandomycin | 1998 |
5-hydroxylation of omeprazole by human liver microsomal fractions from Chinese populations related to CYP2C19 gene dose and individual ethnicity.
Topics: Adult; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; China; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethnicity; Gene Dosage; Genotype; Humans; Hydroxylation; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Substrate Specificity; Troleandomycin | 2000 |