mephenytoin and primidone

mephenytoin has been researched along with primidone in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's3 (15.00)18.2507
2000's2 (10.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campbell, JA; Greenwood, TD; Rathman, TL; Sleevi, MC; Wolfe, JF1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bohlen, N; Hertl, M1
Roger, J; Tassinari, CA1
Buchthal, A1
Lawrence, RC; Lovering, EG; Watson, JR1
Burk, PG; Nathanson, G; Pollack, MA1
Rosenmund, H; Wad, N1
Anast, CS; Russell, B; Saunders, JA; Winnacker, JL; Yeager, H1
Friel, P; Troupin, AS1
Wehrhahn, L; Wiegrebe, W1
Schlunegger, UP; Wehrhahn, L; Wiegrebe, W1
Eadie, MJ1
Burke, JT; Thénot, JP1
György, I; Ilyés, I; Kirilina, S; Tornai, A1
Boothe, DM1
Bialer, M1

Reviews

5 review(s) available for mephenytoin and primidone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Pharmacotherapy of epilepsy. II].
    Die Medizinische Welt, 1978, Jun-02, Volume: 29, Issue:22

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid

1978
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance.
    Clinical pharmacokinetics, 1991, Volume: 21, Issue:1

    Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid

1991
Determination of antiepileptic drugs.
    Journal of chromatography, 1985, May-10, Volume: 340

    Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Chromatography, Liquid; Clonazepam; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mephenytoin; Monitoring, Physiologic; Phenytoin; Primidone; Succinimides; Valproic Acid

1985
Anticonvulsant therapy in small animals.
    The Veterinary clinics of North America. Small animal practice, 1998, Volume: 28, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid

1998

Other Studies

15 other study(ies) available for mephenytoin and primidone

ArticleYear
Synthesis and anticonvulsant activity of some new 2-substituted 3-aryl-4(3H)-quinazolinones.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Anticonvulsants; Bicuculline; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Electroshock; Lethal Dose 50; Male; Methaqualone; Mice; Molecular Structure; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine

1990
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Adverse effects of anti-epileptic drugs].
    Deutsche medizinische Wochenschrift (1946), 1975, Sep-19, Volume: 100, Issue:38

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mephenytoin; Nitrazepam; Phenytoin; Primidone; Succinimides; Thiazines; Trimethadione; Valproic Acid

1975
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
    Advances in neurology, 1975, Volume: 11

    Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Prognosis; Succinimides; Thiazines; Valproic Acid

1975
Simple GLC analysis of anticonvulsant drugs in commercial dosage forms.
    Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:7

    Topics: Anticonvulsants; Chromatography, Gas; Glutethimide; Hydantoins; Mephenytoin; Phenytoin; Primidone; Succinimides

1978
Mucocutaneous eruptions due to antiepileptic drug therapy in children.
    Annals of neurology, 1979, Volume: 5, Issue:3

    Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Erythema Multiforme; Female; Humans; Male; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Stevens-Johnson Syndrome

1979
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography.
    Journal of chromatography, 1978, Jul-01, Volume: 146, Issue:1

    Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone

1978
Rickets in children receiving anticonvulsant drugs. Biochemical and hormonal markers.
    American journal of diseases of children (1960), 1977, Volume: 131, Issue:3

    Topics: Adolescent; Anticonvulsants; Calcium; Child; Child, Preschool; Drug Combinations; Epilepsy; Evaluation Studies as Topic; Female; Humans; Male; Mephenytoin; Phenobarbital; Primidone; Rickets; United States; Vitamin D

1977
Flash-heater ethylation of some antiepileptic drugs.
    Clinical chemistry, 1975, Volume: 21, Issue:6

    Topics: Alkylation; Anticonvulsants; Evaluation Studies as Topic; Hot Temperature; Humans; Mephenytoin; Mephobarbital; Methylation; Phenobarbital; Phenytoin; Primidone; Saliva

1975
[Polarographic determination of some phenylsubstituted anticonvulsants].
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:4

    Topics: Anticonvulsants; Chromatography, Thin Layer; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Polarography; Primidone

1975
[Nitration products of some phenyl-substituted anticonvulsants].
    Pharmaceutica acta Helvetiae, 1975, Volume: 50, Issue:9

    Topics: Anticonvulsants; Mephenytoin; Nitrogen; Phenobarbital; Phenytoin; Primidone

1975
Influence of anticonvulsant drugs on thyroid hormones in epileptic children.
    Acta paediatrica Hungarica, 1985, Volume: 26, Issue:4

    Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Mephenytoin; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine

1985
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
    Epilepsia, 2012, Volume: 53 Suppl 8

    Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid

2012