meperidine and probenecid

meperidine has been researched along with probenecid in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's0 (0.00)18.2507
2000's4 (33.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Oka, T; Sawa, A1
Ahtee, L; Saarnivaara, L1
Sladek, NE1
Goodlet, I; Sugrue, MF1
Eerola, M; Kaukinen, S; Ylitalo, P1

Reviews

2 review(s) available for meperidine and probenecid

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for meperidine and probenecid

ArticleYear
Prolongation of thiopentone anaesthesia by probenecid.
    British journal of anaesthesia, 1980, Volume: 52, Issue:6

    Topics: Anesthesia, Intravenous; Atropine; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Female; Humans; Meperidine; Placebos; Preanesthetic Medication; Probenecid; Thiopental; Time Factors

1980

Other Studies

9 other study(ies) available for meperidine and probenecid

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effects of narcotic analgesics on serotonin metabolism in brain of rats and mice.
    Japanese journal of pharmacology, 1976, Volume: 26, Issue:5

    Topics: Analgesics, Opioid; Animals; Atropine; Brain; Drug Interactions; Fenclonine; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Mice; Mice, Inbred ICR; Morphine; Naloxone; Pargyline; Probenecid; Rats; Serotonin

1976
The effect of pethidine on the 5-hydroxytryptamine and 5-hydroxyindoleacetic acid content of the mouse brain.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:11

    Topics: Animals; Brain Chemistry; Fluorescence; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Meperidine; Mice; Probenecid; Serotonin; Spectrum Analysis

1971
Therapeutic efficacy of cyclophosphamide as a function of inhibition of its metabolism.
    Cancer research, 1972, Volume: 32, Issue:9

    Topics: Alkylation; Animals; Azaguanine; Binding, Competitive; Carcinoma 256, Walker; Cyclophosphamide; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Gonadal Steroid Hormones; Male; Meperidine; Mercaptopurine; Metyrapone; Microsomes, Liver; Morphine; Phenacetin; Proadifen; Probenecid; Quinine; Rats

1972
Effects of acutely administered analgesic drugs on rat brain 5-hydroxytryptamine turnover.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Morphine; Pargyline; Pentazocine; Probenecid; Rats; Serotonin

1972