meperidine and phenytoin

meperidine has been researched along with phenytoin in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199015 (62.50)18.7374
1990's1 (4.17)18.2507
2000's4 (16.67)29.6817
2010's4 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Jolivette, LJ; Ward, KW1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bending, MR; Dollery, CT; Kahn, GC; Mucklow, JC1
Bissada, NK; Finkbeiner, AE; Welch, LT1
Butler, CM; Hill, RM; Horning, MG; Howlin, J1
Gibson, TC1
Cardinal, JA; Verbeeck, RK1
Ghoneim, MM; Pandya, H1
Bacci, MC; Bianchi, C; Bonardi, G; Coppi, G; Molino, C; Tomasi, L; Vidi, A1
Altland, K; Goedee, HW1
Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL1
Collins, VJ1
Cardinal, JA; Verbeeck, RK; Wallace, SM1
Dvorchik, BH1
Kretschzmar, KM; Pond, SM1
Jackson, AJ; Miller, AK; Narang, PK1
Chatterjee, A; Mukheree, J1
GRANT, WM; PECZON, JD1
Duley, L; Henderson-Smart, D1

Reviews

7 review(s) available for meperidine and phenytoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Uropharmacology: X. Central nervous system stimulants and depressants.
    Urology, 1979, Volume: 13, Issue:4

    Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract

1979
Drug metabolism in the human neonate.
    Life sciences, 1975, Mar-01, Volume: 16, Issue:5

    Topics: Adult; Animals; Barbiturates; Caffeine; Epoxy Compounds; Female; Humans; Infant, Newborn; Labor, Obstetric; Lactation; Maternal-Fetal Exchange; Meperidine; Milk; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Placenta; Pregnancy; Time Factors

1975
The heart in myasthenia gravis.
    American heart journal, 1975, Volume: 90, Issue:3

    Topics: Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Synergism; Electrocardiography; Heart; Humans; Lidocaine; Meperidine; Methadone; Morphine; Myasthenia Gravis; Myocarditis; Myocardium; Neuromuscular Junction; Phenytoin; Procaine; Quinidine; Vectorcardiography

1975
[Genetically dependent variability of drug effects].
    Medizinische Klinik, 1970, Aug-28, Volume: 65, Issue:35

    Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temperature; Coumarins; Cyanosis; Deficiency Diseases; Dexamethasone; Dogs; Drug Tolerance; Enzymes; Female; Glucosephosphate Dehydrogenase; Humans; Intraocular Pressure; Isonicotinic Acids; Male; Meperidine; Mice; Oxyphenbutazone; Pharmacogenetics; Phenacetin; Phenylbutazone; Phenytoin; Proteins; Rabbits; Rats; Succinylcholine

1970
SEDATIVES, STIMULANTS, AND INTRAOCULAR PRESSURE IN GLAUCOMA.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 72

    Topics: Anticonvulsants; Barbiturates; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Glaucoma; Hydantoins; Hypnotics and Sedatives; Intraocular Pressure; Meperidine; Mephenesin; Meprobamate; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pharmacology; Phenytoin; Primidone; Promethazine; Reserpine; Tonometry, Ocular; Tranquilizing Agents

1964
Magnesium sulphate versus phenytoin for eclampsia.
    The Cochrane database of systematic reviews, 2003, Issue:4

    Topics: Anticonvulsants; Chlorpromazine; Drug Combinations; Eclampsia; Female; Humans; Magnesium Sulfate; Meperidine; Phenytoin; Pregnancy; Promethazine; Randomized Controlled Trials as Topic

2003

Other Studies

17 other study(ies) available for meperidine and phenytoin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Drug concentration in saliva.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Antipyrine; Chlorpropamide; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Saliva; Tolbutamide

1978
Plasma protein binding of salicylic acid, phenytoin, chlorpromazine, propranolol and pethidine using equilibrium dialysis and ultracentrifugation.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Proteins; Chlorpromazine; Dialysis; Humans; Lipoproteins; Meperidine; Middle Aged; Phenytoin; Propranolol; Protein Binding; Salicylates; Salicylic Acid; Temperature; Time Factors; Ultracentrifugation

1985
Plasma protein binding of bupivacaine and its interaction with other drugs in man.
    British journal of anaesthesia, 1974, Volume: 46, Issue:6

    Topics: Atropine; Binding, Competitive; Blood Proteins; Bupivacaine; Desipramine; Dialysis; Drug Interactions; Heparin; Humans; Meperidine; Phenytoin; Protein Binding; Quinidine

1974
Experimental models for the in vivo evaluation of enzyme induction properties of drugs.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Acetanilides; Amides; Aminopyrine; Amphetamine; Aniline Compounds; Animals; Central Nervous System; Codeine; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Hexobarbital; Male; Meperidine; Mice; Oxotremorine; Pentobarbital; Phenacetin; Phenytoin; Rabbits; Rats; Strychnine; Tolbutamide; Tremorine; Zoxazolamine

1973
Observations on models used for the evaluation of antiarrhythmic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine

1971
Advances in pharmacology related to anesthesia and surgery.
    Industrial medicine & surgery, 1966, Volume: 35, Issue:6

    Topics: Anesthesia; Cardiovascular System; Central Nervous System; Digestive System; Drug Therapy; General Surgery; Humans; Kidney; Meperidine; Morphine; Pharmacology; Phenytoin; Respiratory System

1966
Effect of age and sex on the plasma binding of acidic and basic drugs.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Blood Proteins; Chlorpromazine; Desipramine; Female; Humans; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenytoin; Propranolol; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Sex Factors

1984
Drug disposition during pregnancy.
    International journal of biological research in pregnancy, 1982, Volume: 3, Issue:3

    Topics: Anti-Bacterial Agents; Clorazepate Dipotassium; Diazepam; Digoxin; Female; Furosemide; Humans; Kidney; Kinetics; Lithium; Liver; Meperidine; Pharmaceutical Preparations; Phenytoin; Pregnancy

1982
Effect of phenytoin on meperidine clearance and normeperidine formation.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:5

    Topics: Adult; Drug Interactions; Humans; Male; Meperidine; Metabolic Clearance Rate; Phenytoin

1981
Human blood preservation: effect on in vitro protein binding.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:10

    Topics: Blood Preservation; Blood Proteins; Bretylium Tosylate; Freeze Drying; Humans; In Vitro Techniques; Meperidine; Phenytoin; Protein Binding

1981
Comparative study of different anticonvulsants in eclampsia.
    The journal of obstetrics and gynaecology research, 1997, Volume: 23, Issue:3

    Topics: Adult; Anticonvulsants; Chlorpromazine; Diazepam; Eclampsia; Female; Humans; Magnesium Sulfate; Meperidine; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Promethazine

1997