meperidine and ketobemidone

meperidine has been researched along with ketobemidone in 98 studies

Research

Studies (98)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (32.65)	18.7374
1990's	31 (31.63)	18.2507
2000's	27 (27.55)	29.6817
2010's	8 (8.16)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Rogers, ME; Uwaydah, IM; Waddle, MK	1
Soudijn, W; Tulp, MT; van Steen, BJ; van Wijngaarden, I	1
Lombardo, F; Obach, RS; Waters, NJ	1
Andersen, R; Krohg, K	1
Bondesson, U; Hartvig, P	1
Nielsen, AS; Nielsen, B	1
Andersen, LS; Kjaer, M; Nielsen, H; Olsen, FE; Philipsen, J; Velander, G	1
Banning, A; Kaiser, F; Sjøgren, P	1
Haedersdal, C; Knudsen, F; Nielsen, FE; Nielsen, SL	1
Andersson, L; Askergren, J; Davidson, S; Jakobsson, J; Nilsson, A	1
Jakobsen, S; Sjøgren, P; Valentin, N	1
Bundgaard, H; Christrup, LL; Hansen, LB	1
Buolamwini, JK; Knaus, EE	1
Gelinder, S; Hallin, R; Lang, H; Ohqvist, G; Samuelson, S	1
Kaa, E	1
Blom, H; Nielsen, PT; Nielsen, SE	1
Kaa, E; Steentoft, A; Worm, K	1
Jørgensen, BC; Kolby, P; Pedersen, J; Risbo, A; Schmidt, JF	1
Hyttel, J; Larsen, JJ	1
Holmlund, D; Mätzsch, T	1
Andersson, M; Elgen, K; Hagman, A; Larsson, L; Leward, S; Wolff, T	1
Mather, LE; Owen, H	1
Mather, LE; Owen, H; Rowley, K	1
Kjaer, M; Nielsen, H	1
Breivik, H; Raeder, JC; van der Linden, J	1
Tamsen, A	1
Engberg, G	1
Anderson, P; Arnér, S; Bondesson, U; Boréus, LO; Hartvig, P	3
Bondesson, U; Danielsson, B; Lindberg, C	1
Dahlström, B; Nydahl, PA; Ostelius, J; Rawal, N; Sjöstrand, UH	1
Bondesson, U; Dahlström, B; Hartvig, P; Tamsen, A	1
Abrahamsson, L; Ahnfelt, NO; Bondesson, U; Hartvig, P	1
Grosman, N	1
Enig, B	1
Halenda, SP; Rogers, ME; Thweatt, JR; Wilkinson, DS	1
Christensen, AV; Larsen, JJ	1
Jensen, JE; Munk-Olesen, J	1
Basak, SC; Harriss, DK; Magnuson, VR	1
Andersen, S; Ebert, B; Krogsgaard-Larsen, P	1
Jakobsson, J; Rane, K; Ryberg, G	1
Jensen, NH; Jensen, TS; Sjøgren, P	1
Cody, V; Froimowitz, M	1
Danielsen, AG; Hultberg, IB; Weismann, K	1
Benoni, C; Hedenbro, JL; Jansson, O; Jeppsson, B; Lindblom, A; Törnebrandt, K	1
Kaa, E; Kringsholm, B; Simonsen, KW; Steentoft, A; Worm, K	1
Carlsson, P; Dahl, JB; Daugaard, JJ; Egebo, K; Kehlet, H; Rasmussen, B	1
Andersen, LS; Kjaer, M; Nielsen, H	1
Kaa, E; Teige, B	1
Hallberg, S; Holmström, B; Laugaland, K; Rawal, N	1
Christensen, CB	1
Borgbjerg, FM; Eriksen, J; Groth Clausen, T	1
Bondesson, U; Gerdin, E; Hartvig, P	1
Christensen, CB; Christrup, LL; Kristensen, K; Nielsen, LC	1
Andersen, S; Dickenson, AH; Ebert, B; Kohn, M; Rahman, W; Reeve, A	1
Caudle, RM	1
Andersen, S; Ebert, B; Thorkildsen, C	1
Andersen, S; Christrup, LL; Ebert, B; Hjeds, H; Thorkildsen, C	1
Andreasen, K; Breindahl, T	1
Legeby, MH; Nygårds, EB; Olofsson, CI; Ostman, KM	1
Al-Shurbaji, A; Aschan, J; Hassan, M; Hentschke, P; Ljungman, P; Nilsson, C; Ringdén, O; Svensson, JO	1
Axelson, J; Ingvar, C; Johansson, A; Lundberg, J	1
Rygnestad, T; Slørdal, L	1
Helgadóttir, HL	1
Borchgrevink, PC; Kaasa, S; Klepstad, P; Skogvoll, E	1
Nilsson, U; Rawal, N; Uneståhl, LE; Unosson, M; Zetterberg, C	1
AL-Shurbaji, A; Säwe, J; Svensson, JO	1
Lundberg, J; Persson, K	1
Bondesson, U; Hedeland, M; Sundström, I	1
Al-Shurbaji, A; Säwe, J	1
Andrén, PE; Bondesson, U; Hedeland, M; Sundström, I	1
Al-Shurbaji, A; Tokics, L	1
Ingvar, C; Johansson, A; Kornfält, J; Lundberg, J; Nordin, L; Svensson, L	1
Bondesson, U; Fredriksson, E; Hedeland, M; Lampinen, M	1
PELTOLA, P; SOISALO, P	1
Berge, AB; Hald, K; Istre, O; Kløw, NE; Langebrekke, A; Noreng, HJ	1
PETERSEN, PV	1
Owall, A; Pettersson, PH; Settergren, G	1
BERNSTEIN, A	1
GROSS, F; MEIER, R	1
Jylli, L; Langius-Eklöf, A; Lundeberg, S; Olsson, GL	1
Jakobsson, J; Owall, A; Pettersson, PH	1
Al-Shurbaji, A; Annas, A; Artursson, P; Lazorova, L; Svensson, JO; Yasar, U	1
Andersen, PJ; Dahl, JB; Enggaard, TP; Hansen, M; Henriksen, J; Hilsted, KL; Hjortsø, NC; Jørgensen, DG; Mikkelsen, S	1
Hald, K; Istre, O; Kløw, NE; Qvigstad, E	1
Andrén, PE; Sundström, I; Westerlund, D	1
Bergquist, J; Lanças, FM; Santos-Neto, AJ; Sjöberg, PJ	1
Coop, A; Cunningham, CW; Eddington, ND; Mercer, SL	1
Axelsson, K; Crafoord, K; Darvish, B; Gupta, A; Magnuson, A; Perniola, A	1
Eksborg, S; Lafolie, P; Lundeberg, S; Olsson, GL; Stephanson, N; Stiller, CO	1
Andrén, PE; Arts, J; Sundström, I; Westerlund, D	1
Eksborg, S; Lundeberg, S; Stephanson, N; Stiller, CO	1
Ahlner, J; Bastami, S; Holmlund, B; Norling, C; Trinks, C; Uppugunduri, S; Walz, TM	1
Axelsson, K; Fant, F; Gupta, A; Magnuson, A; Perniola, A	1
Jeppesen, SM; Lund, L; Yderstræde, KB	1
Aasbø, V; Dahl, V; Johansen, PW; Markestad, A; Nordbø, A; Roaldset, AH; Ræder, J; Stubhaug, A; Søeberg, B; Willke, A	1
Srinivas, NR	1

Reviews

3 review(s) available for meperidine and ketobemidone

Article	Year
The scientific basis of patient-controlled analgesia. Anaesthesia and intensive care, 1988, Volume: 16, Issue:4 Topics: Analgesia; Analgesics; Analgesics, Opioid; Humans; Meperidine; Self Administration	1988
The development and clinical use of patient-controlled analgesia. Anaesthesia and intensive care, 1988, Volume: 16, Issue:4 Topics: Analgesia; Analgesics; Analgesics, Opioid; Meperidine; Self Administration	1988
Opioid analgesics as noncompetitive N-methyl-D-aspartate (NMDA) antagonists. Biochemical pharmacology, 1998, Sep-01, Volume: 56, Issue:5 Topics: Analgesics, Opioid; Animals; Binding, Competitive; Dextropropoxyphene; Excitatory Amino Acid Antagonists; Humans; Meperidine; Methadone; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1998

Trials

27 trial(s) available for meperidine and ketobemidone

Article	Year
Premedication before elective breast surgery, a comparison between ketobemidone and midazolam. Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:6 Topics: Aged; Analgesics, Opioid; Anxiety; Breast; Female; Humans; Injections, Intramuscular; Meperidine; Midazolam; Middle Aged; Nausea; Preanesthetic Medication; Vomiting	1991
A comparison between morphine, meperidine and ketobemidone in continuous intravenous infusion for postoperative relief. Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:1 Topics: Double-Blind Method; Female; Humans; Infusion Pumps; Infusions, Intravenous; Male; Meperidine; Middle Aged; Morphine; Pain, Postoperative; Prospective Studies	1991
Less pain with epidural morphine after knee arthroplasty. Acta orthopaedica Scandinavica, 1989, Volume: 60, Issue:4 Topics: Analgesia, Epidural; Analgesics, Opioid; Drug Administration Schedule; Humans; Injections, Intramuscular; Knee Prosthesis; Meperidine; Morphine; Pain, Postoperative; Randomized Controlled Trials as Topic; Severity of Illness Index	1989
Regular interval preventive pain relief compared with on demand treatment after hysterectomy. Pain, 1985, Volume: 21, Issue:2 Topics: Adult; Analgesics, Opioid; Buprenorphine; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Hysterectomy; Meperidine; Middle Aged; Morphinans; Pain, Postoperative	1985
[Comparison of indomethacin and ketobemidone as analgesics in acute cholecystitis]. Klinische Wochenschrift, 1986, Apr-15, Volume: 64, Issue:8 Topics: Acute Disease; Analgesics, Opioid; Cholecystectomy; Cholecystitis; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Meperidine; Middle Aged; Parasympatholytics	1986
Analgesic treatment in acute myocardial infarction. A double-blind comparison of ketobemidone + the spasmolytic A29 (Ketogan) and morphine. Acta medica Scandinavica, 1988, Volume: 223, Issue:5 Topics: Adult; Aged; Allylamine; Amines; Analgesics, Opioid; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Meperidine; Middle Aged; Morphine; Myocardial Infarction; Parasympatholytics	1988
Premedication for day-case surgery: double-blind comparison of ketobemidone + dimethylaminodiphenylbuten (A-29) and morphine + scopolamine. Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:7 Topics: Abortion, Legal; Adolescent; Adult; Allylamine; Ambulatory Surgical Procedures; Amines; Anesthesia, General; Dilatation and Curettage; Drug Therapy, Combination; Female; Humans; Meperidine; Middle Aged; Morphine; Nitrous Oxide; Preanesthetic Medication; Pregnancy; Scopolamine; Thiopental	1986
Respiratory performance after upper abdominal surgery. A comparison of pain relief with intercostal blocks and centrally acting analgesics. Acta anaesthesiologica Scandinavica, 1985, Volume: 29, Issue:4 Topics: Acetanilides; Adult; Aged; Cholecystectomy; Etidocaine; Female; Forced Expiratory Volume; Humans; Intercostal Nerves; Male; Meperidine; Middle Aged; Nerve Block; Pain, Postoperative; Peak Expiratory Flow Rate; Pentazocine; Respiration; Vital Capacity	1985
Epidural morphine for postoperative pain relief: a comparative study with intramuscular narcotic and intercostal nerve block. Anesthesia and analgesia, 1982, Volume: 61, Issue:2 Topics: Adult; Aged; Analgesics, Opioid; Clinical Trials as Topic; Epidural Space; Female; Humans; Injections; Injections, Intramuscular; Intercostal Nerves; Male; Meperidine; Middle Aged; Morphine; Nerve Block; Pain, Postoperative; Random Allocation; Time Factors	1982
[Sublingual buprenorphine in the treatment of pain caused by cancer. Transition to buprenorphine from other opiates]. Ugeskrift for laeger, 1983, Oct-17, Volume: 145, Issue:42 Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Clinical Trials as Topic; Female; Humans; Male; Meperidine; Middle Aged; Morphinans; Morphine Derivatives; Neoplasms; Pain, Intractable; Palliative Care	1983
Oral premedication one hour before minor gynaecological surgery--does it have any effect? A comparison between ketobemidone, lorazepam, propranolol and placebo. Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Double-Blind Method; Female; Humans; Lorazepam; Meperidine; Middle Aged; Preanesthetic Medication; Propranolol; Prospective Studies	1995
Nitrous oxide for colonoscopy discomfort: a randomized double-blind study. Endoscopy, 1994, Volume: 26, Issue:3 Topics: Adult; Analgesics, Opioid; Colonoscopy; Double-Blind Method; Female; Humans; Male; Meperidine; Midazolam; Middle Aged; Nitrous Oxide; Premedication	1994
Immediate and prolonged effects of pre- versus postoperative epidural analgesia with bupivacaine and morphine on pain at rest and during mobilisation after total knee arthroplasty. Acta anaesthesiologica Scandinavica, 1994, Volume: 38, Issue:6 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Inhalation; Anesthesia, Intravenous; Bupivacaine; Female; Humans; Knee Prosthesis; Locomotion; Male; Meperidine; Middle Aged; Morphine; Pain, Postoperative; Postoperative Care; Preoperative Care; Rest; Time Factors	1994
[Bioavailability and analgetic effect of sustained-release ketobemidone capsules in patients with chronic pain of cancer]. Ugeskrift for laeger, 1993, Mar-15, Volume: 155, Issue:11 Topics: Adult; Analgesics, Opioid; Biological Availability; Capsules; Delayed-Action Preparations; Female; Humans; Male; Meperidine; Middle Aged; Neoplasms; Pain, Intractable	1993
Combined spinal epidural block versus spinal and epidural block for orthopaedic surgery. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:7 Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Bupivacaine; Fentanyl; Hip Prosthesis; Humans; Injections, Spinal; Knee Prosthesis; Meperidine; Midazolam; Middle Aged; Morphine; Nerve Block; Neuromuscular Blocking Agents; Pain, Postoperative; Time Factors	1993
Diclofenac in the treatment of pain after caesarean delivery. An opioid-saving strategy. European journal of obstetrics, gynecology, and reproductive biology, 2000, Volume: 88, Issue:2 Topics: Administration, Rectal; Adult; Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Diclofenac; Double-Blind Method; Female; Humans; Meperidine; Pain, Postoperative; Placebos; Pregnancy	2000
Preoperative ropivacaine infiltration in breast surgery. Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:9 Topics: Amides; Anesthesia, Local; Anesthetics, Local; Antiemetics; Female; Humans; Mastectomy, Segmental; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Phenothiazines; Postoperative Nausea and Vomiting; Preoperative Care; Prospective Studies; Ropivacaine	2000
Improved recovery after music and therapeutic suggestions during general anaesthesia: a double-blind randomised controlled trial. Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:7 Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, General; Digestive System Physiological Phenomena; Double-Blind Method; Fatigue; Female; Humans; Length of Stay; Male; Meperidine; Middle Aged; Music Therapy; Pain Measurement; Pain, Postoperative; Postoperative Complications; Postoperative Nausea and Vomiting; Suggestion	2001
Perioperative hypothermia and postoperative opioid requirements. European journal of anaesthesiology, 2001, Volume: 18, Issue:10 Topics: Adult; Analgesics, Opioid; Body Temperature; Female; Humans; Hypothermia, Induced; Hysterectomy; Meperidine; Middle Aged; Pain, Postoperative	2001
Wound infiltration with ropivacaine and fentanyl: effects on postoperative pain and PONV after breast surgery. Journal of clinical anesthesia, 2003, Volume: 15, Issue:2 Topics: Amides; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Combined; Anesthetics, Local; Axilla; Female; Fentanyl; Humans; Injections; Lymph Node Excision; Mastectomy, Segmental; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Ropivacaine	2003
Similar pain scores after early and late extubation in heart surgery with cardiopulmonary bypass. Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:1 Topics: Analgesics, Opioid; Analysis of Variance; Anesthetics, Intravenous; Blood Gas Analysis; Blood Pressure; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Dose-Response Relationship, Drug; Female; Humans; Intubation, Intratracheal; Length of Stay; Male; Meperidine; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Piperidines; Postoperative Care; Propofol; Prospective Studies; Remifentanil; Time Factors	2004
Comparison of the analgesic efficacy of ketobemidone and morphine for management of postoperative pain in children: a randomized, controlled study. Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:10 Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia; Child; Double-Blind Method; Female; Humans; Male; Meperidine; Morphine; Pain Measurement; Pain, Postoperative	2004
Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting. Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:3 Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coronary Artery Bypass; Female; Humans; Injections, Intravenous; Male; Meperidine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Time Factors	2005
The effect of gabapentin on post-operative pain following tonsillectomy in adults. Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:7 Topics: Adolescent; Adult; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lactones; Male; Meperidine; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Sulfones; Tonsillectomy	2006
Laparoscopic occlusion compared with embolization of uterine vessels: a randomized controlled trial. Obstetrics and gynecology, 2007, Volume: 109, Issue:1 Topics: Adult; Analgesics, Opioid; Embolization, Therapeutic; Female; Humans; Laparoscopy; Leiomyoma; Menorrhagia; Meperidine; Middle Aged; Nausea; Pain, Postoperative; Pressure; Recovery of Function; Treatment Outcome; Uterine Neoplasms	2007
Intraabdominal local anaesthetics for postoperative pain relief following abdominal hysterectomy: a randomized, double-blind, dose-finding study. European journal of anaesthesiology, 2009, Volume: 26, Issue:5 Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hysterectomy; Infusions, Parenteral; Levobupivacaine; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Quality of Life	2009
Postoperative pain after abdominal hysterectomy: a randomized, double-blind, controlled trial comparing continuous infusion vs patient-controlled intraperitoneal injection of local anaesthetic. British journal of anaesthesia, 2014, Volume: 112, Issue:2 Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Hysterectomy; Injections, Intraperitoneal; Levobupivacaine; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Treatment Outcome	2014

Other Studies

68 other study(ies) available for meperidine and ketobemidone

Article	Year
N-(2-Cyanoethyl) derivatives of meperidine, ketobemidone, and a potent 6,7-benzomorphan. Journal of medicinal chemistry, 1979, Volume: 22, Issue:7 Topics: Analgesics; Animals; Benzomorphans; Binding, Competitive; Brain; Dihydromorphine; Haplorhini; Humans; In Vitro Techniques; Macaca mulatta; Meperidine; Mice; Morphinans; Morphine Dependence; Nitriles; Piperidines; Rats; Structure-Activity Relationship	1979
Structure-affinity relationship studies on 5-HT1A receptor ligands. 1. Heterobicyclic phenylpiperazines with N4-alkyl substituents. Journal of medicinal chemistry, 1993, Sep-17, Volume: 36, Issue:19 Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Piperazines; Rats; Receptors, Serotonin; Structure-Activity Relationship	1993
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Pain as a major cause of postoperative nausea. Canadian Anaesthetists' Society journal, 1976, Volume: 23, Issue:4 Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Female; Humans; Male; Meperidine; Middle Aged; Morphine; Nausea; Pain, Postoperative; Piperidines	1976
Mass fragmentographic method for the determination of ketobemidone in plasma. Journal of chromatography, 1979, Nov-07, Volume: 179, Issue:1 Topics: Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Meperidine	1979
[Pattern of choice in preparation of attempted suicide by poisoning--with particular reference to changes in the pattern of prescriptions]. Ugeskrift for laeger, 1992, Jul-06, Volume: 154, Issue:28 Topics: Adult; Analgesics; Analgesics, Opioid; Denmark; Dextropropoxyphene; Drug Prescriptions; Female; Humans; Male; Meperidine; Middle Aged; Sex Factors; Suicide, Attempted	1992
Bioavailability and analgesic effect of sustained release cetobemidone capsules in cancer patients with chronic pain of malignant origin. Acta oncologica (Stockholm, Sweden), 1992, Volume: 31, Issue:5 Topics: Adult; Aged; Analgesics, Opioid; Biological Availability; Capsules; Delayed-Action Preparations; Female; Humans; Male; Meperidine; Middle Aged; Neoplasms; Pain, Intractable	1992
Reaction time in cancer patients receiving peripherally acting analgesics alone or in combination with opioids. Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:5 Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hydromorphone; Male; Meperidine; Middle Aged; Morphine; Morphine Derivatives; Neoplasms; Nicotinic Acids; Pain	1992
Silent ischemia and severity of pain in acute myocardial infarction. Angiology, 1991, Volume: 42, Issue:8 Topics: Analgesics, Opioid; Angina Pectoris; Coronary Disease; Exercise Test; Humans; Meperidine; Methotrimeprazine; Myocardial Infarction; Pain Measurement; Retrospective Studies; Time Factors	1991
Respiratory depression during epidural morphine treatment. Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:6 Topics: Administration, Oral; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Opioid; Depression, Chemical; Dextropropoxyphene; Female; Humans; Meperidine; Morphine; Pain, Postoperative; Respiration; Time Factors	1991
Ketobemidone prodrugs for buccal delivery. Acta pharmaceutica Nordica, 1991, Volume: 3, Issue:2 Topics: Administration, Buccal; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Meperidine; Prodrugs	1991
Synthesis and antinociceptive activity of 4-pyridyl and -dihydropyridyl analogues of meperidine and ketobemidone. Drug design and delivery, 1990, Volume: 7, Issue:1 Topics: Analgesics; Analgesics, Opioid; Animals; Magnetic Resonance Spectroscopy; Male; Meperidine; Rats; Rats, Inbred Strains; Spectrophotometry, Infrared; Structure-Activity Relationship	1990
[Narcotic abuse in Jylland. A study based on narcotics and deaths of addicts examined at the Institute of Forensic Medicine, University of Aarhus during the period 1981-1988. 2. Deaths among addicts]. Ugeskrift for laeger, 1990, Apr-09, Volume: 152, Issue:15 Topics: Adolescent; Adult; Alcoholic Intoxication; Amphetamine; Denmark; Dextropropoxyphene; Female; Heroin Dependence; Humans; Male; Meperidine; Methadone; Middle Aged; Opioid-Related Disorders; Substance-Related Disorders	1990
Fatal intoxications in the age group 15-34 years in Denmark in 1984 and 1985. A forensic study with special reference to drug addicts. Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1989, Volume: 103, Issue:2 Topics: Adolescent; Adult; Analgesics, Opioid; Barbiturates; Cause of Death; Cross-Sectional Studies; Denmark; Dextropropoxyphene; Drug Overdose; Heroin; Humans; Incidence; Meperidine; Methadone; Morphine; Substance-Related Disorders	1989
5-HT-uptake inhibition potentiates antinociception induced by morphine, pethidine, methadone and ketobemidone in rats. Acta pharmacologica et toxicologica, 1985, Volume: 57, Issue:3 Topics: Analgesics; Analgesics, Opioid; Animals; Brain; Citalopram; Drug Synergism; Male; Meperidine; Methadone; Morphine; Propylamines; Rats; Rats, Inbred Strains; Reaction Time; Serotonin; Serotonin Antagonists; Synaptosomes	1985
Analgesic effect and bioavailability of oral ketogan given as tablets or mixture to patients with chronic pain of malignant origin. Acta oncologica (Stockholm, Sweden), 1988, Volume: 27, Issue:5 Topics: Administration, Oral; Adult; Aged; Allylamine; Amines; Drug Combinations; Female; Half-Life; Humans; Male; Meperidine; Middle Aged; Neoplasms; Pain, Intractable; Tablets	1988
[Factors affecting analgesia. Self administration of analgesics]. Cahiers d'anesthesiologie, 1985, Volume: 33, Issue:2 Topics: Adult; Aged; Analgesics; Female; Humans; Kinetics; Male; Meperidine; Middle Aged; Morphine; Pain, Postoperative; Self Administration	1985
Clinical pharmacokinetics and oral bioavailability of ketobemidone. European journal of clinical pharmacology, 1980, Volume: 17, Issue:1 Topics: Administration, Oral; Adult; Allylamine; Analgesics, Opioid; Biological Availability; Drug Combinations; Female; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Kinetics; Male; Meperidine; Middle Aged	1980
Synthesis and mass spectra of deuterium-labelled ketobemidone and of some potential ketobemidone metabolites. Acta pharmaceutica Suecica, 1980, Volume: 17, Issue:1 Topics: Analgesics, Opioid; Deuterium; Isotope Labeling; Mass Spectrometry; Meperidine	1980
Single-dose kinetics and bioavailability of ketobemidone. Acta anaesthesiologica Scandinavica. Supplementum, 1982, Volume: 74 Topics: Administration, Oral; Adult; Analgesics, Opioid; Biological Availability; Biotransformation; Female; Humans; Injections, Intravenous; Kinetics; Male; Meperidine; Suppositories	1982
Multiple dose kinetics of ketobemidone in surgical patients. Acta anaesthesiologica Scandinavica. Supplementum, 1982, Volume: 74 Topics: Analgesics, Opioid; Humans; Kinetics; Meperidine; Pain, Postoperative; Postoperative Period; Surgical Procedures, Operative	1982
Simultaneous determination of ketobemidone and its N-demethylated metabolite in patient plasma samples by gas chromatography mass spectrometry with selected ion monitoring. Biomedical mass spectrometry, 1983, Volume: 10, Issue:4 Topics: Analgesics, Opioid; Gas Chromatography-Mass Spectrometry; Humans; Ions; Isonipecotic Acids; Meperidine; Phenols	1983
Histamine release from human basophils and isolated rat mast cells induced by ketobemidone, pethidine and the spasmolytic A29. Acta pharmacologica et toxicologica, 1982, Volume: 50, Issue:1 Topics: Allylamine; Analgesics, Opioid; Animals; Basophils; Butylamines; Histamine Release; Humans; In Vitro Techniques; Mast Cells; Meperidine; Morphine; Parasympatholytics; Rats; Rats, Inbred Strains	1982
Some spiro analogues of the potent analgesic ketobemidone. Journal of medicinal chemistry, 1980, Volume: 23, Issue:6 Topics: Analgesics; Animals; Haplorhini; Meperidine; Rabbits; Rats; Receptors, Opioid; Spiro Compounds; Structure-Activity Relationship	1980
The antinociceptive effect of ketobemidone in comparison with Ketogin. Acta pharmacologica et toxicologica, 1983, Volume: 52, Issue:2 Topics: Allylamine; Amines; Analgesics; Animals; Benzoquinones; Drug Combinations; Electroshock; Male; Meperidine; Mice; Pain; Quinones; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds; Species Specificity; Time Factors	1983
Acute bilateral visual impairment in a drug addict. A case report. Acta ophthalmologica, 1984, Volume: 62, Issue:1 Topics: Adult; Fluorescein Angiography; Heroin Dependence; Humans; Injections, Intravenous; Male; Meperidine; Quinine; Substance-Related Disorders; Vision Disorders; Visual Acuity	1984
Comparative study of lipophilicity versus topological molecular descriptors in biological correlations. Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:4 Topics: Alcohols; Analgesics; Animals; Barbiturates; Chemical Phenomena; Chemistry, Physical; Herbicides; Lethal Dose 50; Lipids; Meperidine; Molecular Conformation; Narcotics; Solubility; Structure-Activity Relationship; Triazines	1984
Clinical pharmacokinetics of ketobemidone. Its bioavailability after rectal administration. European journal of clinical pharmacology, 1981, Volume: 19, Issue:3 Topics: Adult; Allylamine; Biological Availability; Humans; Injections, Intravenous; Kinetics; Male; Meperidine; Parasympatholytics; Rectum; Suppositories	1981
Ketobemidone, methadone and pethidine are non-competitive N-methyl-D-aspartate (NMDA) antagonists in the rat cortex and spinal cord. Neuroscience letters, 1995, Mar-10, Volume: 187, Issue:3 Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Meperidine; Methadone; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord	1995
Disappearance of morphine-induced hyperalgesia after discontinuing or substituting morphine with other opioid agonists. Pain, 1994, Volume: 59, Issue:2 Topics: Adult; Aged; Analgesics, Opioid; Child; Delayed-Action Preparations; Female; Humans; Hyperalgesia; Male; Meperidine; Methadone; Middle Aged; Morphine; Myoclonus; Narcotics; Neoplasms; Pain; Sufentanil	1994
Enantiomeric conformers of the opioid agonist ketobemidone HCl in the crystal state. Chirality, 1993, Volume: 5, Issue:7 Topics: Analgesics, Opioid; Crystallization; Crystallography, X-Ray; Meperidine; Models, Molecular; Molecular Conformation; Molecular Structure; Stereoisomerism; Thermodynamics	1993
[Skin lesions after injection abuse. Chronic changes caused by ketobemidone (Ketogan)]. Ugeskrift for laeger, 1994, Jan-10, Volume: 156, Issue:2 Topics: Aged; Analgesics, Opioid; Chronic Disease; Female; Humans; Injections, Subcutaneous; Male; Meperidine; Middle Aged; Needlestick Injuries; Retrospective Studies; Skin; Skin Ulcer; Substance-Related Disorders	1994
Deaths among drug addicts in Denmark in 1987-1991. Forensic science international, 1994, Aug-10, Volume: 67, Issue:3 Topics: Adolescent; Adult; Alcoholism; Amphetamine; Analgesics, Opioid; Barbiturates; Cannabis; Cause of Death; Denmark; Dextropropoxyphene; Female; Heroin; Humans; Male; Meperidine; Methadone; Morphine; Substance-Related Disorders; Suicide; Survival Rate	1994
Drug-related deaths during the 1980s. A comparative study of drug addict deaths examined at the institutes of forensic medicine in Aarhus, Denmark and Oslo, Norway. International journal of legal medicine, 1993, Volume: 106, Issue:1 Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Benzodiazepines; Cause of Death; Cross-Cultural Comparison; Cross-Sectional Studies; Denmark; Dextropropoxyphene; Drug Overdose; Female; Heroin Dependence; Humans; Illicit Drugs; Incidence; Male; Meperidine; Methadone; Morphine Dependence; Norway; Psychotropic Drugs; Substance-Related Disorders; Suicide; Urban Population	1993
The opioid receptor binding profiles of ketobemidone and morphine. Pharmacology & toxicology, 1993, Volume: 73, Issue:6 Topics: Animals; Brain; Cattle; In Vitro Techniques; Meperidine; Morphine; Receptors, Opioid	1993
Legal opioid consumption in Denmark 1981-1993. European journal of clinical pharmacology, 1995, Volume: 48, Issue:5 Topics: Analgesia; Analgesics, Opioid; Buprenorphine; Denmark; Humans; Legislation, Drug; Meperidine; Methadone; Morphine	1995
Excretion of ketobemidone in human breast milk. Journal of perinatal medicine, 1996, Volume: 24, Issue:3 Topics: Analgesics, Opioid; Cesarean Section; Drug Residues; Female; Humans; Meperidine; Milk, Human; Pain, Postoperative; Pregnancy	1996
The mu1 and mu2 opioid receptor binding of ketobemidone, norketobemidone and 3-dimethylamino-1,1-diphenylbutene. Pharmacology & toxicology, 1996, Volume: 79, Issue:2 Topics: Allylamine; Analgesics, Opioid; Animals; Binding, Competitive; Cattle; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Humans; Isonipecotic Acids; Meperidine; Parasympatholytics; Phenols; Receptors, Opioid, delta; Receptors, Opioid, mu	1996
The opioid ketobemidone has a NMDA blocking effect. Pain, 1996, Volume: 67, Issue:2-3 Topics: Analgesics, Opioid; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Evoked Potentials; Injections, Spinal; Meperidine; Morphine; N-Methylaspartate; Nerve Fibers; Rats; Spinal Cord	1996
Comments on Andersen et al., Pain, 67 (1996) 369. Pain, 1997, Volume: 72, Issue:1-2 Topics: Analgesics, Opioid; Excitatory Amino Acid Antagonists; Humans; Meperidine; Receptors, N-Methyl-D-Aspartate	1997
Ketobemidone plus (RS)-3-dimethylamino-1,1-diphenylbut-1-ene (A29) is more potent at NMDA receptors than ketobemidone alone: evidence for A29 as a non-competitive NMDA receptor antagonist. Pharmacology & toxicology, 1998, Volume: 82, Issue:3 Topics: Allylamine; Analgesics, Opioid; Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; Membrane Potentials; Meperidine; Rats; Receptors, N-Methyl-D-Aspartate	1998
Validation of urine drug-of-abuse testing methods for ketobemidone using thin-layer chromatography and liquid chromatography-electrospray mass spectrometry. Journal of chromatography. B, Biomedical sciences and applications, 1999, Dec-24, Volume: 736, Issue:1-2 Topics: Analgesics, Opioid; Chromatography, Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Meperidine; Quality Control; Sensitivity and Specificity; Substance Abuse Detection	1999
Ketobemidone may alter busulfan pharmacokinetics during high-dose therapy. Therapeutic drug monitoring, 2000, Volume: 22, Issue:4 Topics: Adult; Analgesics, Opioid; Antineoplastic Agents, Alkylating; Busulfan; Drug Interactions; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Meperidine	2000
[Morphine, pethidine or ketobemidone in acute pain--are there significant differences?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Sep-10, Volume: 120, Issue:21 Topics: Acute Disease; Analgesics, Opioid; Drug Interactions; Humans; Meperidine; Morphine; Pain	2000
Pain management practices in children after surgery. Journal of pediatric nursing, 2000, Volume: 15, Issue:5 Topics: Acetaminophen; Analgesics; Child; Child, Preschool; Codeine; Drug Administration Routes; Drug Combinations; Drug Utilization Review; Humans; Iceland; Infant; Meperidine; Pain, Postoperative; Retrospective Studies	2000
Circadian distribution of oral opioid consumption in cancer patients. Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:10 Topics: Adult; Aged; Analgesics, Opioid; Circadian Rhythm; Drug Administration Schedule; Female; Humans; Male; Meperidine; Middle Aged; Neoplasms; Pain; Pain Measurement	2000
Determination of ketobemidone and its metabolites in plasma and urine using solid-phase extraction and liquid chromatography-mass spectrometry. Therapeutic drug monitoring, 2001, Volume: 23, Issue:4 Topics: Analgesics, Opioid; Chromatography, Liquid; Humans; Meperidine; Quality Control; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection	2001
Identification of phase I and phase II metabolites of ketobemidone in patient urine using liquid chromatography-electrospray tandem mass spectrometry. Journal of chromatography. B, Biomedical sciences and applications, 2001, Nov-05, Volume: 763, Issue:1-2 Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Mass Spectrometry; Meperidine; Molecular Weight	2001
The pharmacokinetics of ketobemidone are not affected by CYP2D6 or CYP2C19 phenotype. European journal of clinical pharmacology, 2002, Volume: 57, Issue:12 Topics: Adult; Analgesics, Opioid; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Female; Humans; Male; Meperidine; Mixed Function Oxygenases; Mouth Mucosa	2002
Identification of glucuronide conjugates of ketobemidone and its phase I metabolites in human urine utilizing accurate mass and tandem time-of-flight mass spectrometry. Journal of mass spectrometry : JMS, 2002, Volume: 37, Issue:4 Topics: Analgesics, Opioid; Glucuronides; Humans; Inactivation, Metabolic; Meperidine; Molecular Weight; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2002
The pharmacokinetics of ketobemidone in critically ill patients. British journal of clinical pharmacology, 2002, Volume: 54, Issue:6 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Area Under Curve; Blood Cell Count; C-Reactive Protein; Chromatography, Liquid; Critical Illness; Glomerular Filtration Rate; Half-Life; Humans; Injections, Intravenous; Mass Spectrometry; Meperidine; Middle Aged; Serum Albumin	2002
Validation of a method for quantification of ketobemidone in human plasma with liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Jun-15, Volume: 789, Issue:2 Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Meperidine; Sensitivity and Specificity	2003
The analgesic properties and addiction liability of ketobemidone and morphine. A.M.A. archives of internal medicine, 1958, Volume: 101, Issue:4 Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior, Addictive; Meperidine; Morphine	1958
Laparoscopic occlusion of uterine vessels for the treatment of symptomatic fibroids: Initial experience and comparison to uterine artery embolization. American journal of obstetrics and gynecology, 2004, Volume: 190, Issue:1 Topics: Adult; Analgesics, Opioid; Blood Vessels; Dose-Response Relationship, Drug; Embolization, Therapeutic; Female; Humans; Laparoscopy; Leiomyoma; Magnetic Resonance Imaging; Meperidine; Middle Aged; Pain, Postoperative; Uterine Neoplasms; Uterus; Vascular Surgical Procedures	2004
Studies on a new spasmolytic compound 1,1-diphenyl-3-dimethylaminobutene-1 (A29), related to methadone, and on the combined use of this compound and a potent analgesic, ketobemidone (A21). Acta pharmacologica et toxicologica, 1951, Volume: 7, Issue:1 Topics: Analgesics; Biphenyl Compounds; Humans; Meperidine; Methadone; Parasympatholytics; Piperidines	1951
[Clinical experience with Cliradon, a novel synthetic analgesic agent]. Schweizerische medizinische Wochenschrift, 1949, Dec-03, Volume: 79, Issue:48 Topics: Analgesics, Opioid; Humans; Meperidine	1949
[1-Methyl-4-m-oxyphenylpiperidin-4-äthylketon (Cliradon), a new synthetic analgesic with morphine-like action]. Schweizerische medizinische Wochenschrift, 1949, Dec-03, Volume: 79, Issue:48 Topics: Analgesics, Opioid; Humans; Meperidine	1949
Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:8 Topics: ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Caco-2 Cells; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Isonipecotic Acids; Ketoconazole; Kinetics; Meperidine; Microsomes, Liver; Mutagenesis, Site-Directed; Phenols; Substrate Specificity; Sulfaphenazole; Troleandomycin; Verapamil	2005
Method development for identification of ketobemidone metabolites in microdialysate samples by coupled-column capillary liquid chromatography-tandem mass spectrometry. Journal of chromatography. A, 2008, May-02, Volume: 1189, Issue:1-2 Topics: Animals; Chromatography, High Pressure Liquid; Meperidine; Microdialysis; Molecular Structure; Rats; Reproducibility of Results; Tandem Mass Spectrometry	2008
Simultaneous analysis of five antidepressant drugs using direct injection of biofluids in a capillary restricted-access media-liquid chromatography-tandem mass spectrometry system. Journal of chromatography. A, 2008, May-02, Volume: 1189, Issue:1-2 Topics: Antidepressive Agents; Chromatography, High Pressure Liquid; Isonipecotic Acids; Meperidine; Phenols; Reproducibility of Results; Tandem Mass Spectrometry	2008
Opioids and efflux transporters. Part 3: P-glycoprotein substrate activity of 3-hydroxyl addition to meperidine analogs. Bioorganic & medicinal chemistry letters, 2008, Jun-15, Volume: 18, Issue:12 Topics: ATP Binding Cassette Transporter, Subfamily B; Drug Evaluation, Preclinical; Hydroxyl Radical; Meperidine; Molecular Structure; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity	2008
Pharmacokinetics after an intravenous single dose of the opioid ketobemidone in children. Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:4 Topics: Analgesics, Opioid; Anesthesia; Area Under Curve; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Infant; Infant, Newborn; Injections, Intravenous; Male; Mass Spectrometry; Meperidine	2010
In vivo investigation of brain and systemic ketobemidone metabolism. The Analyst, 2010, Volume: 135, Issue:2 Topics: Animals; Brain; Chromatography, High Pressure Liquid; Excitatory Amino Acid Antagonists; Male; Meperidine; Microdialysis; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry	2010
Pharmacokinetics after a single intravenous dose of the opioid ketobemidone in neonates. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Analgesics, Opioid; Anesthesia, General; Anesthesiology; Area Under Curve; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Infant, Newborn; Injections, Intravenous; Male; Mass Spectrometry; Meperidine	2012
Inhibitory effect of opiates on LPS mediated release of TNF and IL-8. Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:5 Topics: Analgesics, Opioid; Down-Regulation; Fentanyl; Humans; Interleukin-8; Lipopolysaccharides; MAP Kinase Signaling System; Meperidine; Morphine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tramadol; Tumor Necrosis Factor-alpha; U937 Cells	2013
[Calcinosis cutis treatment with extracorporeal shockwave therapy]. Ugeskrift for laeger, 2015, May-25, Volume: 177, Issue:22 Topics: Aged; Analgesics, Opioid; Calcinosis; Female; High-Energy Shock Waves; Humans; Meperidine; Skin Ulcer; Thigh	2015
[From ketobemidone to morphine or oxycodone]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2016, Volume: 136, Issue:18 Topics: Administration, Intravenous; Analgesics, Opioid; Drug Substitution; Humans; Meperidine; Morphine; Norway; Oxycodone; Practice Guidelines as Topic	2016
Reduced Ketobemidone Usage in Quadratus Lumborum Block Patients After Cesarean Delivery: Clinical Pharmacology Views. Anesthesia and analgesia, 2018, Volume: 127, Issue:1 Topics: Abdominal Muscles; Analgesics; Cesarean Section; Female; Humans; Meperidine; Pharmacology, Clinical; Pregnancy	2018