meperidine and dextromethorphan

meperidine has been researched along with dextromethorphan in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's2 (14.29)18.2507
2000's6 (42.86)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B1
Lo, GF; Sinclair, JG1
Babbini, M; Bartoletti, M; Gaiardi, M; Gubellini, C1
Lee, MM; Tao, PL; Wong, CS; Wu, CT; Yeh, CC; Yu, JC1
Chang, FL; Ho, ST; Lin, TC; Wong, CS; Wu, CT; Yeh, CC1
Lee, MM; Lin, TC; Wong, CS; Wu, CT; Yeh, CC; Yu, JC1
Lee, MS; Lu, CH; Wong, CS; Wu, CT; Yang, CP; Yeh, CC; Yu, JC1
Chao, PC; Ho, ST; Jao, SW; Li, CY; Lin, SL; Wong, CS; Yeh, CC1
Chen, SL; Chow, LH; Huang, EY; Tao, PL1
Borel, CO; Lee, MS; Liou, HS; Wu, CT; Yang, CP; Yi, HD; Yu, JC1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1

Reviews

1 review(s) available for meperidine and dextromethorphan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for meperidine and dextromethorphan

ArticleYear
Preincisional dextromethorphan decreases postoperative pain and opioid requirement after modified radical mastectomy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:12

    Topics: Analgesics, Opioid; Anesthesia, General; Antitussive Agents; Dextromethorphan; Female; Humans; Mastectomy, Modified Radical; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Preoperative Care

1999
Postoperative intramuscular dextromethorphan injection provides pain relief and decreases opioid requirement after modified radical mastectomy.
    International journal of surgical investigation, 2000, Volume: 2, Issue:2

    Topics: Analgesics, Opioid; Dextromethorphan; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Injections, Intramuscular; Mastectomy, Modified Radical; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Receptors, N-Methyl-D-Aspartate; Treatment Outcome

2000
Analgesic effects of preincisional administration of dextromethorphan and tenoxicam following laparoscopic cholecystectomy.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:8

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Chlorpheniramine; Cholecystectomy, Laparoscopic; Dextromethorphan; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Injections, Intravenous; Male; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Piroxicam

2004
Oral slow release dextromethorphan premedication provides a pethidine spare effect on posthemorrhoidectomy pain management.
    Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2004, Volume: 42, Issue:2

    Topics: Administration, Oral; Adult; Delayed-Action Preparations; Dextromethorphan; Double-Blind Method; Female; Hemorrhoids; Humans; Male; Meperidine; Middle Aged; Pain, Postoperative; Premedication; Receptors, N-Methyl-D-Aspartate

2004
The interaction effect of perioperative cotreatment with dextromethorphan and intravenous lidocaine on pain relief and recovery of bowel function after laparoscopic cholecystectomy.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:2

    Topics: Analgesics, Opioid; Anesthetics, Local; Cholecystectomy, Laparoscopic; Dextromethorphan; Digestive System; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Injections, Intravenous; Lidocaine; Male; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative

2005

Other Studies

8 other study(ies) available for meperidine and dextromethorphan

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation

2019
The blockade of serotonin uptake and the meperidine-monoamine oxidase inhibitor interaction.
    Proceedings of the Western Pharmacology Society, 1977, Volume: 20

    Topics: Analgesics, Opioid; Animals; Brain; Depression, Chemical; Dextromethorphan; Drug Interactions; In Vitro Techniques; Meperidine; Neurons; Phenelzine; Phenyl Ethers; Propylamines; Rabbits; Serotonin; Synaptosomes

1977
Further evidence for a motility substitution test as a tool to detect the narcotic character of new drugs in rats.
    Neuropharmacology, 1983, Volume: 22, Issue:2

    Topics: Animals; Dextromethorphan; Dextropropoxyphene; Male; Meperidine; Motor Activity; Narcotics; Rats; Rats, Inbred Strains; Time Factors

1983
Postoperative intramuscular dextromethorphan injection provides postoperative pain relief and decreases opioid requirement after hemorrhoidectomy.
    Acta anaesthesiologica Sinica, 1999, Volume: 37, Issue:4

    Topics: Adult; Analgesics, Opioid; Dextromethorphan; Female; Hemorrhoids; Humans; Injections, Intramuscular; Male; Meperidine; Middle Aged; Pain, Postoperative; Receptors, N-Methyl-D-Aspartate

1999
Dextromethorphan differentially affects opioid antinociception in rats.
    British journal of pharmacology, 2005, Volume: 144, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Codeine; Dextromethorphan; Drug Interactions; Male; Meperidine; Morphine; Nalbuphine; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Receptors, Opioid, mu

2005
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014