meperidine and caffeine

meperidine has been researched along with caffeine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199018 (54.55)18.7374
1990's2 (6.06)18.2507
2000's8 (24.24)29.6817
2010's5 (15.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Jolivette, LJ; Ward, KW1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Moffat, AC1
Butler, CM; Hill, RM; Horning, MG; Howlin, J1
Suzuki, EM1
Bloch, B; Smythe, E; Weeks, R1
Bauer, G; Konzett, H; Ziegler, E1
Frank, GB; Jhamandas, K1
Harvey, DJ; Hill, RM; Horning, MG; Nowlin, HJ; Stillwell, WG1
Gorodetzky, CW; Kullberg, MP1
Feingold, A; Miller, RR; Paxinos, J1
Cullen, LF; Packman, DL; Papariello, GJ1
Lasagna, L1
McClure, DA1
Maruta, T; Swanson, DW1
Liu, F; Liu, L; Lu, YQ; Luo, Y; Qiu, FH1
BLOUGH, DS1
BODNER, H; HOWARD, AH; KAPLAN, JH1
JACOB, J; MICHAUD, G1
BOHDANECKY, Z; NECINA, J1
FISCHER, A; TAKACS, L; VARGA, I1
GRANT, WM; PECZON, JD1
Chai, LY; Lu, Y; Tong, XM; Xia, Q; Zhang, X1
Bhanumathy, M; Chandrasekar, SB; Divakar, K; Goli, D; Harisha, R; Pawar, AT; Shivaprasad, HN; Sushma, G1

Reviews

4 review(s) available for meperidine and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug metabolism in the human neonate.
    Life sciences, 1975, Mar-01, Volume: 16, Issue:5

    Topics: Adult; Animals; Barbiturates; Caffeine; Epoxy Compounds; Female; Humans; Infant, Newborn; Labor, Obstetric; Lactation; Maternal-Fetal Exchange; Meperidine; Milk; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Placenta; Pregnancy; Time Factors

1975
Propoxyphene hydrochloride. A critical review.
    JAMA, 1970, Aug-10, Volume: 213, Issue:6

    Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headache; Humans; Indoles; Isoquinolines; Meperidine; Morphine; Nalorphine; Narcotics; Pain; Periodontal Diseases; Phenacetin; Placebos; Postoperative Care; Pregnancy; Puerperal Disorders; Substance Withdrawal Syndrome; Substance-Related Disorders; Tranquilizing Agents

1970
SEDATIVES, STIMULANTS, AND INTRAOCULAR PRESSURE IN GLAUCOMA.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 72

    Topics: Anticonvulsants; Barbiturates; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Glaucoma; Hydantoins; Hypnotics and Sedatives; Intraocular Pressure; Meperidine; Mephenesin; Meprobamate; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pharmacology; Phenytoin; Primidone; Promethazine; Reserpine; Tonometry, Ocular; Tranquilizing Agents

1964

Trials

3 trial(s) available for meperidine and caffeine

ArticleYear
Analgesics for pain relief after gynaecological surgery. A two-phase study.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, Mar-02, Volume: 67, Issue:9

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Benzophenones; Caffeine; Clinical Trials as Topic; Codeine; Dipyrone; Double-Blind Method; Drug Combinations; Female; Humans; Hysterectomy; Injections, Intramuscular; Meperidine; Meprobamate; Pain, Postoperative; Piperidines; Random Allocation; Smoking; Time Factors

1985
Propoxyphene hydrochloride. A critical review.
    JAMA, 1970, Aug-10, Volume: 213, Issue:6

    Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headache; Humans; Indoles; Isoquinolines; Meperidine; Morphine; Nalorphine; Narcotics; Pain; Periodontal Diseases; Phenacetin; Placebos; Postoperative Care; Pregnancy; Puerperal Disorders; Substance Withdrawal Syndrome; Substance-Related Disorders; Tranquilizing Agents

1970
Drug interaction in the field of analgesic drugs.
    Proceedings of the Royal Society of Medicine, 1965, Volume: 58, Issue:11 Part 2

    Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Cyclazocine; Drug Synergism; Humans; Meperidine; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Pentazocine; Phenacetin; Placebos; Tranquilizing Agents; Triflupromazine

1965

Other Studies

27 other study(ies) available for meperidine and caffeine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
The standardisation of thin-layer chromatographic systems for the identification of basic drugs.
    Journal of chromatography, 1975, Jul-16, Volume: 110, Issue:2

    Topics: Amitriptyline; Amphetamine; Caffeine; Chromatography, Thin Layer; Codeine; Hydrogen-Ion Concentration; Lidocaine; Meperidine; Pharmaceutical Preparations; Quinine; Silicon Dioxide; Solvents; Strychnine

1975
Fourier transform infrared analyses of some particulate drug mixtures using a diamond anvil cell with a beam condenser and an infrared microscope.
    Journal of forensic sciences, 1992, Volume: 37, Issue:2

    Topics: Amobarbital; Aspirin; Barbiturates; Caffeine; Chlordiazepoxide; Cocaine; Diphenoxylate; Drug Combinations; Ephedrine; Heroin; Illicit Drugs; Meperidine; Methamphetamine; Niacinamide; Phenacetin; Powders; Secobarbital; Spectrophotometry, Infrared

1992
[On the inhibitory effect of kinins on isolated intestinal sections].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie und experimentelle Pathologie, 1966, Volume: 254, Issue:3

    Topics: Anesthetics, Local; Animals; Atropine; Bradykinin; Caffeine; Duodenum; Ganglionic Blockers; Guanethidine; Ileum; Jejunum; Kallidin; Meperidine; Methadone; Morphine; Phenylbutazone; Rabbits

1966
Effects of drugs acting alone and in combination on the motor activity of intact mice.
    British journal of pharmacology, 1970, Volume: 39, Issue:4

    Topics: Adjuvants, Anesthesia; Aminobutyrates; Animals; Bemegride; Caffeine; Central Nervous System; Central Nervous System Stimulants; Chlorpromazine; Diazepam; Diphenhydramine; Female; Glutamates; Hydroxybutyrates; Lactones; Meperidine; Meprobamate; Mice; Motor Activity; Nikethamide; Phenobarbital; Picrotoxin; Promethazine; Reflex; Scopolamine; Seizures; Strychnine; Tranquilizing Agents

1970
The use of gass chromatography-mass spectrometry methods in perinatal pharmacology.
    Advances in biochemical psychopharmacology, 1973, Volume: 7

    Topics: Barbiturates; Caffeine; Chromatography, Gas; Female; Fetus; Humans; Infant, Newborn; Mass Spectrometry; Maternal-Fetal Exchange; Meperidine; Phenobarbital; Pregnancy; Secobarbital

1973
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cocaine; Codeine; Evaluation Studies as Topic; Glucuronates; Humans; Hydrolysis; Meperidine; Meprobamate; Mescaline; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Naloxone; Pentobarbital; Secobarbital; Substance-Related Disorders

1974
An automated colorimetric method for determination of free salicylic acid in aspirin-containing products.
    Annals of the New York Academy of Sciences, 1968, Nov-15, Volume: 153, Issue:2

    Topics: Analgesics; Aspirin; Autoanalysis; Azepines; Caffeine; Codeine; Colorimetry; Meperidine; Meprobamate; Methods; Phenacetin; Salicylates

1968
4-Dimethyl-amino methyl-2-methyl 1,3 dioxolane--a new potent analgesic agent.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 179, Issue:1

    Topics: Analgesics; Animals; Aspirin; Caffeine; Codeine; Dextropropoxyphene; Dioxoles; Electric Stimulation; Meperidine; Mice; Morphine; Pain; Phenacetin; Quinones; Stimulation, Chemical

1969
Problems with the use of oxycodone compound in patients with chronic pain.
    Pain, 1981, Volume: 11, Issue:3

    Topics: Aspirin; Caffeine; Chronic Disease; Codeine; Dextropropoxyphene; Drug Combinations; Female; Humans; Male; Meperidine; Middle Aged; Oxycodone; Pain; Pentazocine; Phenacetin

1981
[Systematic analysis of basic drugs in plasma using X-5 solid-phase extraction GC-FID and GC-MS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:4

    Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Caffeine; Central Nervous System Stimulants; Chromatography, Gas; Diazepam; Gas Chromatography-Mass Spectrometry; Humans; Hypnotics and Sedatives; Meperidine; Phenothiazines

1996
Some effects of drugs on visual discrimination in the pigeon.
    Annals of the New York Academy of Sciences, 1957, Mar-14, Volume: 66, Issue:3

    Topics: Animals; Caffeine; Chlorpromazine; Columbidae; Humans; Learning; Lysergic Acid Diethylamide; Meperidine; Pentobarbital; Visual Perception

1957
A new compound for analgesia; A.P.C. with demerol.
    Postgraduate medicine, 1958, Volume: 24, Issue:5

    Topics: Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthesia and Analgesia; Antipyretics; Caffeine; Humans; Meperidine; Pain Management; Phenacetin

1958
[The effect of various pharmacological agents (amphetamine, cocaine, caffeine, hexobarbital, meprobamate, morphine, dextromoramide, 1-methadone, pethidine and CT 3570) on the time of exhaustion and behavior of animals swimming at 20 degrees C].
    Medicina experimentalis : International journal of experimental medicine, 1960, Volume: 2

    Topics: Amphetamine; Amphetamines; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior; Caffeine; Central Nervous System Stimulants; Cocaine; Dextromoramide; Hexobarbital; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed

1960
Course of some pharmacological tests in functionally decorticated animals.
    Physiologia bohemoslovenica, 1963, Volume: 12

    Topics: Amphetamine; Amphetamines; Animals; Caffeine; Cerebral Cortex; Cerebral Decortication; Chlorpromazine; Ethers; Magnesium Sulfate; Meperidine; Morphine; Pentylenetetrazole; Phenylbutazone; Pregnanediones; Strychnine; Thiopental

1963
[STUDY OF THE INTERMEDIATE METABOLISM OF DRUGS USING PARTIAL HEPATECTOMY].
    Kiserletes orvostudomany, 1963, Volume: 15

    Topics: Barbiturates; Caffeine; Chemical and Drug Induced Liver Injury; Chloralose; Hepatectomy; Hepatitis; Hypnotics and Sedatives; Insulin; Liver; Meperidine; Muscle Relaxants, Central; Pentylenetetrazole; Rats; Research; Splenectomy; Theophylline; Toxicology; Tranquilizing Agents; Urethane

1963
[Mechanisms of pethidine-induced vasodilatation].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2004, Volume: 33, Issue:2

    Topics: Animals; Caffeine; Calcium; Male; Meperidine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasodilator Agents

2004
Involvement of opioid, adenosine and 5-HT(3) receptors in antinociceptive effects of an ayurvedic polyherbal formulation.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2011, Volume: 20, Issue:1

    Topics: Analgesics; Analgesics, Opioid; Animals; Caffeine; Drug Combinations; Medicine, Ayurvedic; Meperidine; Mice; Naloxone; Narcotic Antagonists; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Purinergic P1; Receptors, Serotonin, 5-HT3; Tail

2011