meperidine and antipyrine

meperidine has been researched along with antipyrine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's1 (6.67)18.2507
2000's6 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Jolivette, LJ; Ward, KW1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Bending, MR; Dollery, CT; Kahn, GC; Mucklow, JC1
Eichhorst, BC; Seeds, AE; Stolee, A1
Carson, RJ; Gaylard, DG; Reynolds, F1
Cousins, MJ; Gourlay, GK; Hall, PD; Knights, KM; Lunam, CA; O'Brien, P1
Knott, C; Reynolds, F; Vella, LM1
Hamshaw-Thomas, A; Reynolds, F1
Burns, JJ1
Chandra, P; Lal, A; Pande, SB; Pandey, K1
Altland, K; Goedee, HW1

Reviews

1 review(s) available for meperidine and antipyrine

ArticleYear
[Genetically dependent variability of drug effects].
    Medizinische Klinik, 1970, Aug-28, Volume: 65, Issue:35

    Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temperature; Coumarins; Cyanosis; Deficiency Diseases; Dexamethasone; Dogs; Drug Tolerance; Enzymes; Female; Glucosephosphate Dehydrogenase; Humans; Intraocular Pressure; Isonicotinic Acids; Male; Meperidine; Mice; Oxyphenbutazone; Pharmacogenetics; Phenacetin; Phenylbutazone; Phenytoin; Proteins; Rabbits; Rats; Succinylcholine

1970

Trials

2 trial(s) available for meperidine and antipyrine

ArticleYear
A randomized prospective controlled study of the metabolism and hepatotoxicity of halothane in humans.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:4

    Topics: Antipyrine; Blood Pressure; Enflurane; Half-Life; Halothane; Humans; Indocyanine Green; Kinetics; Liver; Liver Function Tests; Meperidine; Prospective Studies; Random Allocation

1987
Dipyrone for treatment of post-operative pain.
    Anaesthesia, 1973, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Alkanesulfonates; Analgesics; Antipyrine; Clinical Trials as Topic; Female; Humans; Injections, Intravenous; Male; Meperidine; Middle Aged; Placebos; Postoperative Complications

1973

Other Studies

12 other study(ies) available for meperidine and antipyrine

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Drug concentration in saliva.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Antipyrine; Chlorpropamide; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Saliva; Tolbutamide

1978
Permeability of human chorion laeve to diazepam and meperidine.
    Obstetrics and gynecology, 1976, Volume: 47, Issue:1

    Topics: Aminohippuric Acids; Antipyrine; Cell Membrane Permeability; Chorion; Diazepam; Diffusion; Extraembryonic Membranes; Female; Fetal Blood; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Meperidine; Placenta; Pregnancy

1976
Effect of umbilical perfusate pH and controlled maternal hypotension on placental drug transfer in the rabbit.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:1

    Topics: Anesthesia, Obstetrical; Animals; Antipyrine; Bupivacaine; Chromatography, Gas; Female; Hydrogen-Ion Concentration; Hypotension; Infusions, Intravenous; Maternal-Fetal Exchange; Meperidine; Placenta; Pregnancy; Rabbits

1990
Transfer of fentanyl across the rabbit placenta. Effect of umbilical flow and concurrent drug administration.
    British journal of anaesthesia, 1986, Volume: 58, Issue:1

    Topics: Analgesics; Animals; Antipyrine; Bupivacaine; Female; Fentanyl; Fetal Blood; Kinetics; Maternal-Fetal Exchange; Meperidine; Pregnancy; Rabbits; Regional Blood Flow

1986
Placental transfer of bupivacaine, pethidine and lignocaine in the rabbit. Effect of umbilical flow rate and protein content.
    British journal of obstetrics and gynaecology, 1985, Volume: 92, Issue:7

    Topics: Animals; Antipyrine; Blood Flow Velocity; Blood Proteins; Bupivacaine; Female; Lidocaine; Maternal-Fetal Exchange; Meperidine; Perfusion; Pregnancy; Protein Binding; Rabbits; Umbilical Cord

1985
IV. Pharmacogenetics and drug toxicity. Variation of drug metabolism in animals and the prediction of drug action in man.
    Annals of the New York Academy of Sciences, 1968, Jul-31, Volume: 151, Issue:2

    Topics: Animals; Antipyrine; Ascorbic Acid; Barbiturates; Carbon Isotopes; Cats; Chlordan; Dicumarol; Dogs; Environmental Exposure; Ethyl Biscoumacetate; Glucuronates; Guinea Pigs; Haplorhini; Horses; Humans; Meperidine; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Phenols; Phenylbutazone; Rabbits; Species Specificity; Sulfates

1968