menthol and n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide

menthol has been researched along with n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's7 (70.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambrosino, P; Bertamino, A; Campiglia, P; Ciaglia, T; de la Torre-Martinez, R; Di Sarno, V; Fernandez Carvajal, A; Ferrer-Montiel, A; Gomez-Monterrey, I; Gonzalez Muniz, R; Iraci, N; Musella, S; Novellino, E; Ostacolo, C; Soldovieri, MV; Taglialatela, M1
Colburn, RW; Flores, CM; Liu, Y; Lubin, ML; Qin, N; Reitz, TL; Wang, Y1
Reilly, CA; Sabnis, AS; Shadid, M; Yost, GS1
Fernández-Ballester, G; Ferrer-Montiel, A; Malkia, A; Pertusa, M; Viana, F1
Denda, M; Denda, S; Tsutsumi, M1
Belmonte, C; Morenilla-Palao, C; Valero, M; Viana, F1
Acosta, MC; Belmonte, C; del Olmo, S; Dhaka, A; Echevarria, D; Gallar, J; Madrid, R; Morenilla-Palao, C; Parra, A; Viana, F1
Beltrán, C; Darszon, A; De Blas, G; de la Vega-Beltrán, JL; Gibbs, GM; Martínez-López, P; Monroy, E; O'Bryan, MK; Orta, G; Treviño, CL1
Andrade, VA; Araujo, IG; Barbosa-Filho, JM; Braz, AL; Chaves, CG; Correia, Nde A; Cruz, Jdos S; de Albuquerque, JG; de Almeida, MM; de Medeiros, IA; Gomes, MA; Leite, Mde F; Nunes, XP; Pesquero, JL; Pinho-da-Silva, L; Silva, DF1
Chen, HK; Chu, YH; Fan, HC; Lee, FP; Liu, SC; Lu, HH; Wang, HW; Yu, CJ1

Other Studies

10 other study(ies) available for menthol and n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide

ArticleYear
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators.
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Models, Molecular; Molecular Structure; Rats; Structure-Activity Relationship; TRPM Cation Channels; Tryptamines

2016
Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: Action Potentials; Amino Acid Sequence; Animals; Calcium; Cell Line; Cloning, Molecular; Cold Temperature; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Fluorometry; Ganglia, Spinal; Gene Library; Humans; Menthol; Mice; Molecular Sequence Data; Mustard Plant; Oocytes; Patch-Clamp Techniques; Plant Oils; Pyrazines; Pyridines; Pyrimidinones; Rats; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Transfection; TRPM Cation Channels; Xenopus laevis

2006
Human lung epithelial cells express a functional cold-sensing TRPM8 variant.
    American journal of respiratory cell and molecular biology, 2008, Volume: 39, Issue:4

    Topics: Amino Acid Sequence; Animals; Bronchi; Capsaicin; Cell Line; Cold Temperature; Cytokines; Endoplasmic Reticulum; Epithelial Cells; Humans; Lung; Menthol; Molecular Sequence Data; Pyrazines; Pyridines; Thapsigargin; Thermoreceptors; Thermosensing; TRPM Cation Channels

2008
Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.
    Molecular pain, 2009, Nov-03, Volume: 5

    Topics: Animals; Capsaicin; Clotrimazole; Cold Temperature; Humans; Imidazoles; Ion Channel Gating; Menthol; Mice; Models, Molecular; Molecular Dynamics Simulation; Mutant Proteins; Mutation; Phenotype; Pyrazines; Pyridines; Structure-Activity Relationship; TRPM Cation Channels; Tyrosine

2009
Topical application of TRPM8 agonists accelerates skin permeability barrier recovery and reduces epidermal proliferation induced by barrier insult: role of cold-sensitive TRP receptors in epidermal permeability barrier homoeostasis.
    Experimental dermatology, 2010, Volume: 19, Issue:9

    Topics: Administration, Cutaneous; Anilides; Animals; Cells, Cultured; Epidermis; Homeostasis; Humans; Hyperplasia; Keratinocytes; Male; Menthol; Mice; Mice, Hairless; Permeability; Pyrazines; Pyridines; Ruthenium Red; Skin Diseases; TRPM Cation Channels

2010
Pharmacological and functional properties of TRPM8 channels in prostate tumor cells.
    Pflugers Archiv : European journal of physiology, 2011, Volume: 461, Issue:1

    Topics: Arginine; Calcium; Cell Line; Cell Line, Tumor; Cell Membrane; Clotrimazole; Cold Temperature; Endoplasmic Reticulum; Glycine; Humans; Male; Menthol; Prostate; Prostatic Neoplasms; Pyrazines; Pyridines; Pyrimidinones; TRPM Cation Channels

2011
Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea.
    Nature medicine, 2010, Volume: 16, Issue:12

    Topics: 4-Aminopyridine; Animals; Cold Temperature; Cornea; Dry Eye Syndromes; Menthol; Mice; Mice, Transgenic; Ocular Physiological Phenomena; Pyrazines; Pyridines; Shaker Superfamily of Potassium Channels; Tears; Thermoreceptors; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels

2010
TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction.
    Journal of cellular physiology, 2011, Volume: 226, Issue:6

    Topics: Acrosome Reaction; Animals; Capsaicin; Humans; Ion Channel Gating; Male; Menthol; Mice; Mice, Knockout; Pyrazines; Pyridines; Pyrimidinones; Spermatozoa; Temperature; Testis; TRPM Cation Channels

2011
TRPM8 Channel Activation Induced by Monoterpenoid Rotundifolone Underlies Mesenteric Artery Relaxation.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Animals; Blotting, Western; Calcium; Calcium Signaling; Capsaicin; Cold Temperature; Cytosol; In Vitro Techniques; Ion Channel Gating; Male; Menthol; Mesenteric Arteries; Monoterpenes; Pyrazines; Pyridines; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Ruthenium Red; TRPM Cation Channels; TRPV Cation Channels; Vasodilation

2015
The identification of the TRPM8 channel on primary culture of human nasal epithelial cells and its response to cooling.
    Medicine, 2017, Volume: 96, Issue:31

    Topics: Blotting, Western; Cells, Cultured; Cold Temperature; Epithelial Cells; Female; Fibroblasts; Humans; Immunohistochemistry; Keratin-14; Keratin-18; Male; Menthol; Mucin 5AC; Nasal Mucosa; Pyrazines; Pyridines; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sensory System Agents; TRPM Cation Channels

2017