menthol has been researched along with capsaicin in 114 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (6.14) | 18.2507 |
| 2000's | 40 (35.09) | 29.6817 |
| 2010's | 48 (42.11) | 24.3611 |
| 2020's | 19 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Backlund, A; Bohlin, L; Gottfries, J; Larsson, J | 1 |
| Nilius, B; Owsianik, G; Talavera, K; Voets, T | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ann, J; Blumberg, PM; Choi, K; Esch, TE; Ha, HJ; Hwang, SW; Kim, H; Kim, HS; Kim, M; Kim, YH; Lee, J; Pearce, LV; Thorat, SA; Turcios, NA | 1 |
| Erickson, RP; Simon, SA; Wang, Y | 1 |
| Cliff, MA; Green, BG | 1 |
| Kuwahara, M; Sekizawa, S; Sugano, S; Tsubone, H | 1 |
| Grattan, TJ; Laude, EA; Morice, AH; Wright, CE | 1 |
| Bowen, WP; Grattan, TJ; Morice, AH; Wright, CE | 1 |
| Kanamaru, A; Kojima, K; Kuwahara, M; Mutoh, T; Nishimura, R; Sasaki, N; Tsubone, H | 1 |
| Fall, M; Geirsson, G; Lindström, S | 1 |
| Green, BG; McAuliffe, BL | 1 |
| Clapham, DE | 1 |
| Kahl, U | 1 |
| Lane, HW; Rice, BL; Rose, MS; Vickers, ZM | 1 |
| Babes, A; Pluteanu, F; Reid, G | 1 |
| Green, BG; Schullery, MT | 1 |
| Baccei, ML; Bardoni, R; Fitzgerald, M | 1 |
| Arsenault, J; Dorion, D; Praud, JP; Reix, P; Roulier, S | 1 |
| Anand, P | 1 |
| Jordt, SE; Julius, D; McKemy, DD | 1 |
| Droogmans, G; Flockerzi, V; Janssens, A; Nilius, B; Voets, T; Wissenbach, U | 1 |
| Babes, A; Reid, G; Zorzon, D | 1 |
| Barritt, GJ; Zhang, L | 1 |
| Hayashi, F; Mizuyachi, K; Niki, T; Tsukimi, Y; Yamasaki, T | 1 |
| Green, BG | 1 |
| Akirav, C; Alvarez-Reeves, M; George, P; Green, BG | 1 |
| Chen, M; Gu, JG; Ling, J; Xing, H | 1 |
| Brauchi, S; Latorre, R; Orta, G; Rosenmann, E; Salazar, M | 1 |
| Dubin, AE; Hwang, SW; Macpherson, LJ; Miyamoto, T; Patapoutian, A; Story, GM | 1 |
| Katsura, H; Noguchi, K; Sakagami, M; Tsuzuki, K | 1 |
| Kalantzis, A; Loescher, AR; Robinson, PP | 1 |
| Alqatari, M; Ernfors, P; Hjerling-Leffler, J; Koltzenburg, M | 1 |
| Albin, KC; Carstens, E; Carstens, MI | 1 |
| Horie, S; Matsumoto, K; Nakamura, T; Penuelas, A; Tashima, K; Tsuchiya, S; Yano, S | 1 |
| Endo, T; Hayashi, S; Kubo, Y; Nakamura, E; Takeuchi, K | 1 |
| Chen, M; Gu, JG; Ling, J; Tan, W; Xing, H | 1 |
| Dhaka, A; Earley, TJ; Patapoutian, A; Watson, J | 1 |
| Harada, K; Ikeda, S; Kamikawa, Y; Kawahira, K; Nomoto, Y; Ohwatashi, A; Yoshida, A | 1 |
| Reilly, CA; Sabnis, AS; Shadid, M; Yost, GS | 1 |
| Engel, S; Lee, BB; McLachlan, E; Wasner, G | 1 |
| Alenmyr, L; Greiff, L; Högestätt, ED; Zygmunt, PM | 1 |
| Flühr, K; Lötsch, J; Neddermeyer, TJ | 1 |
| Dhaka, A; Mandadi, S; McKemy, DD; Nakanishi, ST; Patapoutian, A; Takashima, Y; Whelan, PJ | 1 |
| Bautista, DM; Gerhold, KA | 1 |
| Fernández-Ballester, G; Ferrer-Montiel, A; Malkia, A; Pertusa, M; Viana, F | 1 |
| Crawford, DC; Gereau, RW; Mennerick, S; Moulder, KL; Story, GM | 1 |
| Cahusac, PM | 1 |
| Filippov, IB; Kuliieva, IeM; Prevarskaia, N; Shuba, IaM; Skryma, R; Vladymyrova, IA | 1 |
| Patel, T; Yosipovitch, G | 2 |
| Basbaum, AI; Bráz, JM | 1 |
| Gu, J; Sarria, I | 1 |
| Ebihara, S; Ebihara, T; Kohzuki, M; Sumi, Y | 1 |
| Carstens, E; Carstens, MI; Cheung, S; Furrer, S; Ivanov, MA; Klein, AH; Sawyer, CM; Simons, CT; Slack, JP; Zanotto, KL | 1 |
| Beltrán, C; Darszon, A; De Blas, G; de la Vega-Beltrán, JL; Gibbs, GM; Martínez-López, P; Monroy, E; O'Bryan, MK; Orta, G; Treviño, CL | 1 |
| About, I; Curtis, TM; El Karim, IA; Irwin, CR; Killough, SA; Linden, GJ; Lundy, FT; McGahon, MK | 1 |
| Anand, P; Roberts, K; Shenoy, R | 1 |
| Dong, L; Li, Q; Luo, P; Rong, W; Sun, B; Zhou, Y | 1 |
| Baggio, CH; Freitas, CS; Iacomini, M; Marcon, R; Marques, MC; Rae, GA; Santos, AR; Sassaki, GL; Smiderle, FR; Werner, MF | 1 |
| Adams, E; D'Autry, W; Dewever, C; Forier, M; Hoogmartens, J; Pauwels, J; Van den Bossche, L; Van Schepdael, A; Vandenwaeyenberg, S; Wolfs, K | 1 |
| Isami, K; Kaneko, S; Nakagawa, T; Nakamura, S; Shirakawa, H; Zhao, M | 1 |
| Hayashi, N; Kashima, H | 1 |
| Bende, M; Millqvist, E; Ternesten-Hasséus, E | 1 |
| Baad-Hansen, L; List, T; Lu, S; Svensson, P; Zhang, Z | 1 |
| Keast, JR; O'Mullane, LM; Osborne, PB | 1 |
| Gu, JG; Ling, JX; Xu, GY; Zuo, X | 1 |
| Alpizar, YA; Radwan, A; Radwan, I; Sanchez, A; Talavera, K; Voets, T | 1 |
| Saito, M | 1 |
| Horie, S; Takayama, H; Terada, Y; Tominaga, M; Uchida, K; Watanabe, T | 1 |
| Barkin, RL | 1 |
| Anderson, EM; Caudle, RM; Jenkins, AC; Neubert, JK | 1 |
| Carstens, E; Carstens, MI; Davoodi, A; Joe, CL; Klein, AH; Takechi, K | 1 |
| Ando, T; Baad-Hansen, L; Naganawa, T; Svensson, P | 1 |
| Andersen, HH; Arendt-Nielsen, L; Gazerani, P; Nikbakht, A; Poulsen, JN; Uchida, Y | 1 |
| Mahns, DA; Nagi, SS; Samour, MS | 1 |
| Drummond, PD; Finch, PM | 1 |
| Baad-Hansen, L; Lu, S; Svensson, P; Zhang, Z | 1 |
| Aicher, SA; Hegarty, DM; Hermes, SM | 1 |
| Andrade, VA; Araujo, IG; Barbosa-Filho, JM; Braz, AL; Chaves, CG; Correia, Nde A; Cruz, Jdos S; de Albuquerque, JG; de Almeida, MM; de Medeiros, IA; Gomes, MA; Leite, Mde F; Nunes, XP; Pesquero, JL; Pinho-da-Silva, L; Silva, DF | 1 |
| Fujita, F; Matsui, H; Shimada, T; Suzuki, Y; Takaishi, M; Tominaga, M; Uchida, K | 1 |
| Ebihara, S; Ebihara, T; Izukura, H; Miyagi, M; Okuni, I; Sekiya, H | 1 |
| Metz, M; Staubach, P | 1 |
| Aicher, SA; Hegarty, DM; Hermes, SM; Yang, K | 1 |
| Paisley, P; Serpell, M | 1 |
| Carpenter, GH; Hans, J; Houghton, JW; Ley, JP; Pesaro, M; Proctor, G | 1 |
| Borad, N; Catich, E; Li, N; McKemy, DD; Ongun, S; Palkar, R; Sarkisian, A | 1 |
| Cao, T; Tey, HL; Yosipovitch, G | 1 |
| Alhaddad, M; Boen, M; Goldman, MP; Guiha, I; Wu, DP | 1 |
| Jankowska, M; Kletkiewicz, H; Maliszewska, J; Rogalska, J; Stankiewicz, M | 1 |
| Gibson, OR; Hayes, M; Wrightson, JG | 1 |
| Breza, JM; Chaudhari, N; Leijon, SCM; Neves, AF; Roper, SD; Simon, SA | 1 |
| Lötsch, J; Weyer-Menkhoff, I | 1 |
| Fujii, N; Hatta, A; Kurose, M; Meng, ID; Okamoto, K; Sullivan, C; Yamamura, K | 1 |
| Galli, U; Genazzani, AA; Griglio, A; Pirali, T; Serafini, M; Tron, GC | 1 |
| Carpenter, GH; Gardner, A | 1 |
| Ando, H; Hossain, MZ; Kitagawa, J; Unno, S | 1 |
| Demers, D; Denis, TE; Kalliel, JR; Mecum, NE; Meng, ID; Sullivan, CE | 1 |
| Bhadada, SK; Bhunia, RK; Bishnoi, M; Kaur, J; Khare, P; Kondepudi, KK; Kuhad, A; Kumar, V; Mahajan, N; Shafi, S | 1 |
| Courtin, AS; Mouraux, A | 1 |
| Argôlo, IPR; Parisi, JR; Silva, JRTD; Silva, MLD | 1 |
| Alvarez-Berdugo, D; Clavé, P; Ortega, O; Rofes, L; Tomsen, N | 1 |
| Pointer, B; Rainville, P; Yang, J | 1 |
| Choi, J; Jang, L; Lee, S | 1 |
| Antunes-Ricardo, M; Cortés-Ferré, HE; Guerrero-Analco, JA; Gutiérrez-Uribe, JA; Martínez-Avila, M; Monribot-Villanueva, JL | 1 |
| Fossataro, C; Mattei, R; Pafundi, PC; Salerni, A; Savino, G | 1 |
| Imamura, S; Ishimaru, T; Kido, M; Kimori, K; Matsumoto, K; Nakashima, Y; Nakayasu, A; Okawara, M; Yoshikawa, T | 1 |
| Bhunia, RK; Bishnoi, M; Kaur, J; Kaur, S; Kondepudi, KK; Kuhad, A; Kumar, V; Singh, DP | 1 |
| Cai, Y; Chen, J; Li, H; Liu, B; Mei, Y; Shi, Q; Tang, H; Wang, X; Yang, M; Zhao, N | 1 |
| Heffernan, SM; Jeffries, O; John, K; Page, J; Peel, J; Tallent, J; Waldron, M | 1 |
| Aisala, H; Hoppu, U; Puputti, S; Roukka, S; Sandell, M; Seppä, L | 1 |
| Adriaens, N; Bruisten, SM; Pennekamp, AM; van Dam, AP | 1 |
| Gandini Júnior, LG; Jacob, HB; Kim, KB; Monini, ADC; Schneider, PP | 1 |
| Morita, Y; Takahashi, M; Yoshikawa, T | 1 |
14 review(s) available for menthol and capsaicin
| Article | Year |
|---|---|
Sensing with TRP channels.
Topics: Animals; Humans; Ligands; Models, Biological; Phylogeny; Temperature; Transient Receptor Potential Channels | 2005 |
The bladder cooling reflex and the use of cooling as stimulus to the lower urinary tract.
Topics: Adult; Animals; Capsaicin; Child; Cold Temperature; Humans; Infant; Menthol; Muscle, Smooth; Physical Stimulation; Reflex; Urinary Bladder; Urinary Bladder Diseases | 1999 |
Lessons from peppers and peppermint: the molecular logic of thermosensation.
Topics: Animals; Capsaicin; Capsicum; Humans; Mentha piperita; Menthol; Plant Oils; Thermoreceptors | 2003 |
Molecular and cellular mechanisms of trigeminal chemosensation.
Topics: Amides; Animals; Capsaicin; Humans; Menthol; Mustard Plant; Plant Oils; Somatosensory Cortex; Taste Perception; Trigeminal Nerve | 2009 |
Therapy of pruritus.
Topics: Adrenal Cortex Hormones; Antidepressive Agents; Antipsychotic Agents; Capsaicin; Emollients; Histamine Antagonists; Humans; Immunologic Factors; Menthol; Pruritus | 2010 |
The management of chronic pruritus in the elderly.
Topics: Administration, Oral; Administration, Topical; Aged; Antipruritics; Cannabinoids; Capsaicin; Central Nervous System Agents; Chronic Disease; Emollients; Glucocorticoids; Histamine Antagonists; Humans; Immunologic Factors; Menthol; Phototherapy; Pruritus; Salicylic Acid; Skin Aging | 2010 |
Brown adipose tissue as a therapeutic target for human obesity.
Topics: Adipose Tissue, Brown; Age Factors; Animals; Capsaicin; Capsicum; Cold Temperature; Energy Metabolism; Environmental Exposure; Fluorodeoxyglucose F18; Humans; Ion Channels; Menthol; Mitochondrial Proteins; Obesity; Phytotherapy; Plant Extracts; Positron-Emission Tomography; Radiopharmaceuticals; Thermogenesis; Transient Receptor Potential Channels; Uncoupling Protein 1 | 2013 |
The pharmacology of topical analgesics.
Topics: Administration, Cutaneous; Administration, Oral; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Camphor; Capsaicin; Cryotherapy; Cyclooxygenase Inhibitors; Humans; Hyperthermia, Induced; Irritants; Menthol; Pain Management; Salicylates | 2013 |
Topical treatment in pain medicine: from ancient remedies to modern usage.
Topics: Administration, Cutaneous; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Clonidine; Cocaine; Epidermis; History, 18th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Ketamine; Mandragora; Menthol; Nociception; Pain Management; Plant Extracts | 2015 |
Chemical Senses Affecting Cough and Swallowing.
Topics: Acids; Angiotensin-Converting Enzyme Inhibitors; Animals; Capsaicin; Cigarette Smoking; Cough; Deglutition; Humans; Menthol; Nicotine; Theophylline | 2016 |
Itch Management: Topical Agents.
Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Antipruritics; Camphor; Cannabinoid Receptor Agonists; Capsaicin; Chronic Disease; Dermatologic Agents; Glycerol; Humans; Menthol; Narcotic Antagonists; Pruritus; Skin Care; Sodium Chloride; Urea | 2016 |
The role of topiceuticals in cancer pain.
Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Cancer Pain; Capsaicin; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Humans; Lidocaine; Menthol; Neuralgia; Pain Management; Pain Measurement | 2017 |
Chronic Pruritus in the Geriatric Population.
Topics: Aged; Aged, 80 and over; Aging; Antidepressive Agents; Antipruritics; Calcineurin Inhibitors; Capsaicin; Cholestasis; Chronic Disease; Emollients; Histamine; Histamine Antagonists; Humans; Kidney Failure, Chronic; Liver Diseases; Menthol; Nervous System Diseases; Palliative Care; Paraneoplastic Syndromes; Pruritus; Skin Aging; Skin Diseases; Urticaria | 2018 |
Targeting Chemosensory Ion Channels in Peripheral Swallowing-Related Regions for the Management of Oropharyngeal Dysphagia.
Topics: Animals; Capsaicin; Citric Acid; Deglutition Disorders; Humans; Ion Channels; Menthol; Molecular Targeted Therapy; Neuronal Plasticity; Randomized Controlled Trials as Topic; Sensory System Agents | 2020 |
11 trial(s) available for menthol and capsaicin
| Article | Year |
|---|---|
Sensitization and desensitization to capsaicin and menthol in the oral cavity: interactions and individual differences.
Topics: Adult; Capsaicin; Drug Interactions; Female; Humans; Individuality; Male; Menthol; Mouth; Nerve Fibers; Stimulation, Chemical; Time Factors | 1996 |
Menthol desensitization of capsaicin irritation. Evidence of a short-term anti-nociceptive effect.
Topics: Administration, Topical; Adult; Antipruritics; Capsaicin; Drug Administration Schedule; Female; Humans; Male; Menthol; Nerve Fibers; Pain Measurement; Reaction Time; Stimulation, Chemical; Time Factors; Tongue | 2000 |
Modulation of oral heat and cold pain by irritant chemicals.
Topics: Acrolein; Adolescent; Adult; Capsaicin; Cold Temperature; Female; Hot Temperature; Humans; Irritants; Male; Menthol; Middle Aged; Mustard Plant; Nociceptors; Plant Oils; Temperature; Thermosensing; Tongue; Transient Receptor Potential Channels | 2008 |
Capsaicin or menthol sensitization induces quantitative but no qualitative changes to thermal and mechanical pain thresholds.
Topics: Adolescent; Adult; Antipruritics; Capsaicin; Female; Humans; Hyperalgesia; Male; Menthol; Middle Aged; Pain Measurement; Pain Threshold; Physical Stimulation; Young Adult | 2009 |
Facial skin blood flow responses to irritant stimuli in the oral cavity.
Topics: Adult; Capsaicin; Dose-Response Relationship, Drug; Face; Female; Flavoring Agents; Humans; Irritants; Japan; Kinetics; Male; Menthol; Mouth Mucosa; Pain Measurement; Regional Blood Flow; Sensory System Agents; Skin; Young Adult | 2013 |
Inhalation of menthol reduces capsaicin cough sensitivity and influences inspiratory flows in chronic cough.
Topics: Administration, Inhalation; Adult; Aged; Antitussive Agents; Capsaicin; Chronic Disease; Cough; Double-Blind Method; Female; Humans; Inhalation; Irritants; Male; Menthol; Middle Aged; Spirometry | 2013 |
Somatosensory profiling of intra-oral capsaicin and menthol in healthy subjects.
Topics: Administration, Topical; Adult; Analysis of Variance; Capsaicin; Cross-Over Studies; Double-Blind Method; Facial Pain; Female; Gingiva; Humans; Male; Menthol; Models, Biological; Pain Measurement; Pain Threshold; Statistics, Nonparametric | 2013 |
Spatial and Temporal Effects of Capsaicin and Menthol on Intraoral Somatosensory Sensitivity.
Topics: Adult; Capsaicin; Cross-Over Studies; Double-Blind Method; Female; Gingiva; Humans; Male; Menthol; Pain Threshold; Sensation; Sensory System Agents; Spatio-Temporal Analysis | 2015 |
A Single Site, Open Label Clinical Trial, Evaluating the Duration, Efficacy, and Safety of a Novel Lip Plumper.
Topics: Administration, Cutaneous; Adult; Capsaicin; Cinnamomum zeylanicum; Cosmetic Techniques; Dermal Fillers; Drug Compounding; Female; Humans; Lip; Male; Menthol; Middle Aged; Prospective Studies; Skin Aging; Treatment Outcome; Viscoelastic Substances; Young Adult | 2018 |
TRPA1 Sensitization Produces Hyperalgesia to Heat but not to Cold Stimuli in Human Volunteers.
Topics: Acrolein; Adult; Capsaicin; Cold Temperature; Cross-Over Studies; Female; Healthy Volunteers; Hot Temperature; Humans; Hyperalgesia; Male; Menthol; Neuralgia; Pain Threshold; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels; Young Adult | 2019 |
Topical application of isolated menthol and combined menthol-capsaicin creams: Exercise tolerance, thermal perception, pain, attentional focus and thermoregulation in the heat.
Topics: Adult; Body Temperature Regulation; Capsaicin; Cross-Over Studies; Exercise Tolerance; Female; Hot Temperature; Humans; Male; Menthol; Pain; Pain Perception; Thermosensing | 2023 |
89 other study(ies) available for menthol and capsaicin
| Article | Year |
|---|---|
Expanding the ChemGPS chemical space with natural products.
Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2005 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic.
Topics: Analgesics; Animals; Capsaicin; CHO Cells; Cricetulus; Drug Discovery; Hyperalgesia; Mice, Inbred ICR; Neuralgia; Phenylurea Compounds; Swine; Thiazoles; TRPV Cation Channels | 2020 |
Selectivity of lingual nerve fibers to chemical stimuli.
Topics: Ammonium Chloride; Animals; Calcium Chloride; Capsaicin; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Lanthanum; Lingual Nerve; Mechanoreceptors; Menthol; Nerve Fibers; Neural Conduction; Nicotine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium Chloride; Temperature; Tongue | 1993 |
Nasal receptors responding to cold and l-menthol airflow in the guinea pig.
Topics: Action Potentials; Animals; Antipruritics; Capsaicin; Cold Temperature; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Male; Menthol; Nasal Cavity; Nerve Fibers; Neurons, Afferent; Thermoreceptors | 1996 |
Capsaicin and neurokinin A-induced bronchoconstriction in the anaesthetised guinea-pig: evidence for a direct action of menthol on isolated bronchial smooth muscle.
Topics: Airway Resistance; Anesthesia; Animals; Bronchi; Bronchoconstriction; Calcium; Capsaicin; Guinea Pigs; In Vitro Techniques; Male; Menthol; Muscle, Smooth; Neurokinin A | 1997 |
Identification of the L-menthol binding site in guinea-pig lung membranes.
Topics: Animals; Benzazepines; Binding Sites; Camphor; Capsaicin; Cell Membrane; Eugenol; Guinea Pigs; In Vitro Techniques; Lung; Male; Menthol; Radioligand Assay; Tritium | 1998 |
The posterior nasal nerve plays an important role on cardiopulmonary reflexes to nasal application of capsaicin, distilled water and l-menthol in anesthetized dogs.
Topics: Administration, Intranasal; Anesthesia; Animals; Antipruritics; Capsaicin; Dogs; Electrophysiology; Female; Heart; Lung; Male; Menthol; Nasal Cavity; Neurons, Afferent; Reflex; Water | 1999 |
Signal transduction. Hot and cold TRP ion channels.
Topics: Animals; Calcium Channels; Capsaicin; Cold Temperature; Ganglia, Spinal; Hot Temperature; Ion Channel Gating; Menthol; Mice; Mouth; Signal Transduction; Skin Physiological Phenomena; Taste; Touch; Trigeminal Ganglion; TRPC Cation Channels | 2002 |
[TRP channels--sensitive for heat and cold, capsaicin and menthol].
Topics: Animals; Calcium Channels; Capsaicin; Capsicum; Cold Temperature; Hot Temperature; Humans; Ion Channels; Menthol; Sensory Receptor Cells; Taste; Thermoreceptors | 2002 |
Simulated microgravity [bed rest] has little influence on taste, odor or trigeminal sensitivity.
Topics: Adult; Bed Rest; Butyrates; Capsaicin; Citric Acid; Fluid Shifts; Head-Down Tilt; Humans; Male; Menthol; Odorants; Quinine; Sensory Thresholds; Smell; Sodium Chloride; Sodium Glutamate; Sucrose; Taste Threshold; Terpenes; Weightlessness Simulation | 2001 |
A cold- and menthol-activated current in rat dorsal root ganglion neurones: properties and role in cold transduction.
Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Capsaicin; Cold Temperature; Electrophysiology; Fluorescent Dyes; Ganglia, Spinal; Imidazoles; In Vitro Techniques; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Menthol; Nerve Growth Factor; Organic Chemicals; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium; Stereoisomerism; Thermoreceptors | 2002 |
Stimulation of bitterness by capsaicin and menthol: differences between lingual areas innervated by the glossopharyngeal and chorda tympani nerves.
Topics: Adolescent; Adult; Antipruritics; Capsaicin; Chorda Tympani Nerve; Dose-Response Relationship, Drug; Female; Glossopharyngeal Nerve; Humans; Male; Menthol; Middle Aged; Quinine; Sucrose; Taste; Time Factors; Tongue | 2003 |
Development of nociceptive synaptic inputs to the neonatal rat dorsal horn: glutamate release by capsaicin and menthol.
Topics: Action Potentials; Afferent Pathways; Animals; Animals, Newborn; Antipruritics; Calcium; Capsaicin; Excitatory Postsynaptic Potentials; Glutamic Acid; Menthol; Nociceptors; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Drug; Rhizotomy; Synapses | 2003 |
Effects of C fiber blockade on cardiorespiratory responses to laryngeal stimulation in concious lambs.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antipruritics; Blood Pressure; Capsaicin; Carbon Dioxide; Cardiovascular Physiological Phenomena; Diaphragm; Electrocardiography; Electromyography; Goats; Heart Rate; Laryngeal Nerves; Menthol; Nerve Fibers, Unmyelinated; Reflex; Respiration; Respiratory Function Tests; Songbirds; Wakefulness; Water | 2003 |
Capsaicin and menthol in the treatment of itch and pain: recently cloned receptors provide the key.
Topics: Administration, Topical; Animals; Antipruritics; Capsaicin; Humans; Menthol; Pain; Pruritus Ani; Receptors, Drug; Thermoreceptors | 2003 |
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.
Topics: Capsaicin; Cell Line; Cold Temperature; Electric Conductivity; Hot Temperature; Humans; Ion Channel Gating; Ion Channels; Ligands; Membrane Potentials; Menthol; Models, Biological; Neoplasm Proteins; Patch-Clamp Techniques; Receptors, Drug; TRPM Cation Channels | 2004 |
Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor.
Topics: Animals; Ankyrins; Calcium; Calcium Channels; Calcium Signaling; Capsaicin; Cells, Cultured; Cold Temperature; Drug Synergism; Ganglia, Spinal; Ion Channels; Menthol; Mustard Plant; Neoplasm Proteins; Nerve Growth Factor; Neurons, Afferent; Plant Extracts; Plant Oils; Pyrimidinones; Rats; Thermosensing; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels | 2004 |
Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells.
Topics: Androgens; Apoptosis; Base Sequence; Calcium; Capsaicin; Cell Survival; DNA Primers; Humans; Immunohistochemistry; Ion Channels; Ion Transport; Male; Menthol; Neoplasm Proteins; Prostatic Neoplasms; Sequence Homology, Nucleic Acid; TRPM Cation Channels | 2004 |
Cold response of the bladder in guinea pig: involvement of transient receptor potential channel, TRPM8.
Topics: Afferent Pathways; Animals; Capsaicin; Cold Temperature; Female; Ganglia, Spinal; Guinea Pigs; Hexamethonium; Ion Channels; Menthol; Muscle Contraction; Nerve Fibers, Unmyelinated; Reflex; Urinary Bladder; Urination | 2005 |
Lingual heat and cold sensitivity following exposure to capsaicin or menthol.
Topics: Capsaicin; Cold Temperature; Hot Temperature; Humans; Ion Channels; Menthol; Models, Biological; Perception; Taste; Thermoreceptors; Time Factors; Tongue; TRPC Cation Channels | 2005 |
Chemesthesis and taste: evidence of independent processing of sensation intensity.
Topics: Adolescent; Adult; Capsaicin; Female; Humans; Male; Menthol; Middle Aged; Psychophysics; Sodium Chloride; Stimulation, Chemical; Sucrose; Taste; Taste Buds; Thermosensing | 2005 |
Chemical and cold sensitivity of two distinct populations of TRPM8-expressing somatosensory neurons.
Topics: Animals; Capsaicin; Cells, Cultured; Cold Temperature; Dose-Response Relationship, Drug; Hyperalgesia; Menthol; Neurons, Afferent; Nociceptors; Pain Threshold; Posterior Horn Cells; Rats; Sensitivity and Specificity; Tissue Distribution; TRPM Cation Channels | 2006 |
A hot-sensing cold receptor: C-terminal domain determines thermosensation in transient receptor potential channels.
Topics: Analysis of Variance; Calcium; Capsaicin; Cell Line, Transformed; Cloning, Molecular; Diagnostic Imaging; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Humans; Immunohistochemistry; Membrane Potentials; Menthol; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Temperature; Thermoreceptors; Thermosensing; Transfection; Transient Receptor Potential Channels; TRPM Cation Channels; TRPV Cation Channels | 2006 |
More than cool: promiscuous relationships of menthol and other sensory compounds.
Topics: Animals; Animals, Newborn; Antipruritics; Calcium; Camphor; Capsaicin; Cells, Cultured; Cricetinae; Cricetulus; Diagnostic Imaging; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Ganglia, Spinal; Keratinocytes; Membrane Potentials; Menthol; Mice; Neurons, Afferent; Patch-Clamp Techniques; Rats; Temperature; Transfection; Transient Receptor Potential Channels | 2006 |
Differential expression of capsaicin-, menthol-, and mustard oil-sensitive receptors in naive rat geniculate ganglion neurons.
Topics: Animals; Ankyrins; Calcium Channels; Capsaicin; Geniculate Ganglion; Male; Menthol; Mustard Plant; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neurons; Plant Oils; Rats; Rats, Sprague-Dawley; RNA, Messenger; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels; TRPV Cation Channels | 2006 |
Effects of capsaicin and menthol on oral thermal sensory thresholds.
Topics: Adult; Analysis of Variance; Capsaicin; Case-Control Studies; Drug Interactions; Female; Humans; Menthol; Mouth; Nerve Fibers; Perception; Sensory Thresholds; Stimulation, Chemical; Thermosensing; Time Factors | 2007 |
Emergence of functional sensory subtypes as defined by transient receptor potential channel expression.
Topics: Acrolein; Aging; Animals; Animals, Newborn; Calcium Channels; Capsaicin; Cell Differentiation; Cell Lineage; Cells, Cultured; Cold Temperature; Embryo, Mammalian; Embryonic Development; Ganglia, Spinal; Menthol; Mice; Mice, Inbred C57BL; Neurons, Afferent; Nociceptors; Plant Lectins; RNA, Messenger; Thermoreceptors; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels | 2007 |
Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine.
Topics: Animals; Capsaicin; Disulfides; Gastrointestinal Motility; In Vitro Techniques; Intestines; Isothiocyanates; Male; Menthol; Mice; Pyrimidinones; RNA, Messenger; Sulfinic Acids; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels | 2007 |
Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer.
Topics: Animals; Ankyrins; Calcium Channel Agonists; Calcium Channels; Capsaicin; Cell Line; Epithelial Cells; Gastric Mucosa; Isothiocyanates; Menthol; Pyrimidinones; Rats; Temperature; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels; TRPV Cation Channels; Wound Healing | 2007 |
TRPM8 mechanism of cold allodynia after chronic nerve injury.
Topics: Animals; Capsaicin; Cells, Cultured; Chronic Disease; Cold Temperature; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Ligation; Male; Menthol; Neurons, Afferent; Pain Measurement; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Skin; TRPM Cation Channels | 2007 |
Visualizing cold spots: TRPM8-expressing sensory neurons and their projections.
Topics: Afferent Pathways; Animals; Antipruritics; Blood Vessels; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cold Temperature; Ganglia, Spinal; Gene Expression Regulation; Green Fluorescent Proteins; Menthol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons, Afferent; Spinal Cord; TRPM Cation Channels; TRPV Cation Channels | 2008 |
Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats.
Topics: Animals; Antipruritics; Capsaicin; Carbachol; Female; Menthol; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Temperature; TRPM Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2008 |
Human lung epithelial cells express a functional cold-sensing TRPM8 variant.
Topics: Amino Acid Sequence; Animals; Bronchi; Capsaicin; Cell Line; Cold Temperature; Cytokines; Endoplasmic Reticulum; Epithelial Cells; Humans; Lung; Menthol; Molecular Sequence Data; Pyrazines; Pyridines; Thapsigargin; Thermoreceptors; Thermosensing; TRPM Cation Channels | 2008 |
Residual spinothalamic tract pathways predict development of central pain after spinal cord injury.
Topics: Adult; Capsaicin; Cold Temperature; Female; Histamine; Hot Temperature; Humans; Male; Menthol; Middle Aged; Nerve Fibers; Neuralgia; Nociceptors; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Prognosis; Sensation; Spinal Cord Injuries; Spinothalamic Tracts | 2008 |
TRPV1-mediated itch in seasonal allergic rhinitis.
Topics: Acrolein; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Antipruritics; Arachidonic Acids; Calcium Channel Blockers; Calcium Channels; Capsaicin; Endocannabinoids; Humans; Menthol; Mustard Plant; Nasal Provocation Tests; Nerve Tissue Proteins; Plant Oils; Polyunsaturated Alkamides; Pruritus; Rhinitis, Allergic, Seasonal; Sensory System Agents; Severity of Illness Index; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels | 2009 |
Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels.
Topics: Afferent Pathways; Animals; Animals, Newborn; Capsaicin; Cold Temperature; Hindlimb; In Vitro Techniques; Menthol; Mice; Mice, Knockout; Motor Activity; Motor Neurons; Patch-Clamp Techniques; Periodicity; Sensory System Agents; Spinal Cord; TRPM Cation Channels; TRPV Cation Channels | 2009 |
Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.
Topics: Animals; Capsaicin; Clotrimazole; Cold Temperature; Humans; Imidazoles; Ion Channel Gating; Menthol; Mice; Models, Molecular; Molecular Dynamics Simulation; Mutant Proteins; Mutation; Phenotype; Pyrazines; Pyridines; Structure-Activity Relationship; TRPM Cation Channels; Tyrosine | 2009 |
Comparative effects of heterologous TRPV1 and TRPM8 expression in rat hippocampal neurons.
Topics: Animals; Capsaicin; Hippocampus; Ion Channel Gating; Menthol; Neurons; Neurotransmitter Agents; Rats; Ruthenium Red; Synaptic Transmission; Tetrodotoxin; Transfection; TRPM Cation Channels; TRPV Cation Channels | 2009 |
Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle.
Topics: Acrolein; Action Potentials; Animals; Ankyrins; Calcium Channels; Camphor; Capsaicin; Evoked Potentials; Hair Follicle; In Vitro Techniques; Isothiocyanates; Male; Mechanoreceptors; Menthol; Physical Stimulation; Pyrimidinones; Rats; Rats, Wistar; Ruthenium Red; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels | 2009 |
[Modulation of the smooth muscle contractions of the rat vas deferens by TRPM8 channel agonist menthol].
Topics: Animals; Calcium; Calcium-Transporting ATPases; Capsaicin; Carbachol; Cold Temperature; In Vitro Techniques; Intracellular Membranes; Isotonic Solutions; Male; Menthol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Muscarinic; Sarcoplasmic Reticulum; TRPM Cation Channels; Vas Deferens | 2009 |
Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli.
Topics: Activating Transcription Factor 3; Analysis of Variance; Animals; Capsaicin; Cell Count; Formaldehyde; Ganglia, Spinal; Immunohistochemistry; Menthol; Mice; Mice, Knockout; Mustard Plant; Neurons, Afferent; Nociceptors; Pain Measurement; Plant Oils; TRPV Cation Channels | 2010 |
Menthol response and adaptation in nociceptive-like and nonnociceptive-like neurons: role of protein kinases.
Topics: Adaptation, Physiological; Animals; Calcium; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Female; Ganglia, Spinal; Isothiocyanates; Male; Menthol; Neurons; Nociceptors; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley | 2010 |
Sensory stimulation to improve swallowing reflex and prevent aspiration pneumonia in elderly dysphagic people.
Topics: Activities of Daily Living; Aged; Capsaicin; Cold Temperature; Deglutition; Deglutition Disorders; Hot Temperature; Humans; Menthol; Piper nigrum; Pneumonia, Aspiration; Reflex; Sensory System Agents; Thermoreceptors; Thermosensing | 2011 |
A tingling sanshool derivative excites primary sensory neurons and elicits nocifensive behavior in rats.
Topics: Acrolein; Amides; Animals; Antipruritics; Behavior, Animal; Calcium; Capsaicin; Cells, Cultured; Ganglia, Spinal; Humans; Male; Menthol; Models, Animal; Plant Extracts; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Zanthoxylum | 2011 |
TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction.
Topics: Acrosome Reaction; Animals; Capsaicin; Humans; Ion Channel Gating; Male; Menthol; Mice; Mice, Knockout; Pyrazines; Pyridines; Pyrimidinones; Spermatozoa; Temperature; Testis; TRPM Cation Channels | 2011 |
Human dental pulp fibroblasts express the "cold-sensing" transient receptor potential channels TRPA1 and TRPM8.
Topics: Acetanilides; Acrolein; Adult; Blotting, Western; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Capsaicin; Cells, Cultured; Cold Temperature; Cytophotometry; Dental Pulp; Fibroblasts; Humans; Immunohistochemistry; Membrane Proteins; Menthol; Nerve Tissue Proteins; Nociceptors; Physical Stimulation; Purines; Reverse Transcriptase Polymerase Chain Reaction; Thermosensing; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; Young Adult | 2011 |
A novel human volunteer pain model using contact heat evoked potentials (CHEP) following topical skin application of transient receptor potential agonists capsaicin, menthol and cinnamaldehyde.
Topics: Acrolein; Adult; Capsaicin; Electroencephalography; Evoked Potentials; Female; Hot Temperature; Human Experimentation; Humans; Male; Menthol; Middle Aged; Models, Biological; Pain; Pain Measurement; Pain Threshold; Sensory System Agents; Skin; Transient Receptor Potential Channels; Young Adult | 2011 |
Sensitivity of bronchopulmonary receptors to cold and heat mediated by transient receptor potential cation channel subtypes in an ex vivo rat lung preparation.
Topics: Acetanilides; Acrolein; Animals; Capsaicin; Cold Temperature; Hot Temperature; In Vitro Techniques; Lung; Male; Menthol; Purines; Rats; Rats, Sprague-Dawley; Respiratory System; Sensory System Agents; TRPM Cation Channels | 2011 |
Antinociception of β-D-glucan from Pleurotus pulmonarius is possibly related to protein kinase C inhibition.
Topics: Acid Sensing Ion Channels; Acrolein; Analgesics; Animals; Capsaicin; Enzyme Activation; Glucans; Male; Menthol; Mice; Nerve Tissue Proteins; Nociception; Pleurotus; Protein Kinase C; Protein Kinase Inhibitors; Sodium Channels; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2012 |
Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a
Topics: Analgesics, Non-Narcotic; Camphor; Capsaicin; Chromatography, Gas; Chromatography, Liquid; Liquid-Liquid Extraction; Menthol; Ointments; Pharmaceutical Preparations; Salicylates; Salicylic Acid; Sensitivity and Specificity | 2012 |
Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice.
Topics: Animals; Behavior, Animal; Calcium Channels; Capsaicin; Cisplatin; Cryopyrin-Associated Periodic Syndromes; Ganglia, Spinal; Hyperalgesia; Isothiocyanates; Male; Menthol; Mice; Mice, Inbred C57BL; Nociception; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2012 |
Co-cultures provide a new tool to probe communication between adult sensory neurons and urothelium.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Capsaicin; Carbazoles; Coculture Techniques; Dronabinol; Female; Fura-2; Ganglia, Spinal; Immunohistochemistry; Indole Alkaloids; Indoles; Menthol; Models, Animal; Nerve Growth Factor; Phalloidine; Polyisoprenyl Phosphates; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sesquiterpenes; TRPV Cation Channels; Urothelium | 2013 |
Operant behavioral responses to orofacial cold stimuli in rats with chronic constrictive trigeminal nerve injury: effects of menthol and capsazepine.
Topics: Animals; Behavior, Animal; Capsaicin; Cold Temperature; Conditioning, Operant; Facial Nerve; Facial Pain; Hyperalgesia; Male; Menthol; Neuralgia; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Trigeminal Nerve; Trigeminal Nerve Injuries; TRPM Cation Channels | 2013 |
Lack of correlation between the amplitudes of TRP channel-mediated responses to weak and strong stimuli in intracellular Ca(2+) imaging experiments.
Topics: Acrolein; Animals; Calcium; Calcium Signaling; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Flow Cytometry; Fura-2; HEK293 Cells; Humans; Leucine; Menthol; Pregnenolone; Sulfonamides; Transfection; TRPV Cation Channels | 2013 |
Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree.
Topics: Africa; Alkaloids; Calcium; Capsaicin; Humans; Ibogaine; Menthol; Molecular Structure; Plant Bark; Pyrimidinones; Transient Receptor Potential Channels; Trees; TRPV Cation Channels; Voacanga | 2014 |
The effects of a co-application of menthol and capsaicin on nociceptive behaviors of the rat on the operant orofacial pain assessment device.
Topics: Analysis of Variance; Animals; Capsaicin; Conditioning, Operant; Facial Pain; Male; Menthol; Nociception; Pain Measurement; Rats; Rats, Sprague-Dawley; Temperature; TRPM Cation Channels; TRPV Cation Channels | 2014 |
Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses.
Topics: Acrolein; Action Potentials; Animals; Capsaicin; Cold Temperature; Cymenes; Dose-Response Relationship, Drug; Eugenol; Hot Temperature; Male; Menthol; Monoterpenes; Mustard Plant; Neurons; Neurons, Afferent; Nociceptive Pain; Plant Oils; Rats, Sprague-Dawley; Sensory System Agents; Thermosensing; Tongue; Trigeminal Ganglion; TRPV Cation Channels | 2014 |
Influence of topical application of capsaicin, menthol and local anesthetics on intraoral somatosensory sensitivity in healthy subjects: temporal and spatial aspects.
Topics: Administration, Topical; Adult; Analysis of Variance; Anesthetics, Local; Antipruritics; Capsaicin; Dose-Response Relationship, Drug; Facial Pain; Female; Healthy Volunteers; Humans; Hyperalgesia; Male; Menthol; Pain Threshold; Sensory System Agents; Time Factors; Visual Analog Scale; Young Adult | 2015 |
Cold and L-menthol-induced sensitization in healthy volunteers--a cold hypersensitivity analogue to the heat/capsaicin model.
Topics: Administration, Topical; Adult; Capsaicin; Cold Temperature; Female; Hand; Hot Temperature; Humans; Hyperalgesia; Hypersensitivity; Male; Menthol; Pain; Pain Measurement; Pain Threshold; Skin; Skin Temperature; Time Factors | 2015 |
Cav3.2-expressing low-threshold C fibres in human hairy skin contribute to cold allodynia--a non-TRPV1- and non-TRPM8-dependent phenomenon.
Topics: Adult; Benzeneacetamides; Capsaicin; Cold Temperature; Female; Humans; Male; Menthol; Myalgia; Nerve Fibers, Unmyelinated; Pain Measurement; Pain Perception; Physical Stimulation; Pyridines; Sensory Thresholds; Skin; Thermosensing; TRPM Cation Channels; TRPV Cation Channels; Young Adult | 2015 |
Denervation of the Lacrimal Gland Leads to Corneal Hypoalgesia in a Novel Rat Model of Aqueous Dry Eye Disease.
Topics: Animals; Capsaicin; Cornea; Denervation; Disease Models, Animal; Dose-Response Relationship, Drug; Dry Eye Syndromes; Hypesthesia; Lacrimal Apparatus; Male; Menthol; Pain Perception; Rats; Rats, Sprague-Dawley; Tears | 2015 |
TRPM8 Channel Activation Induced by Monoterpenoid Rotundifolone Underlies Mesenteric Artery Relaxation.
Topics: Animals; Blotting, Western; Calcium; Calcium Signaling; Capsaicin; Cold Temperature; Cytosol; In Vitro Techniques; Ion Channel Gating; Male; Menthol; Mesenteric Arteries; Monoterpenes; Pyrazines; Pyridines; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Ruthenium Red; TRPM Cation Channels; TRPV Cation Channels; Vasodilation | 2015 |
Reciprocal effects of capsaicin and menthol on thermosensation through regulated activities of TRPV1 and TRPM8.
Topics: Adult; Analgesics; Capsaicin; Cell Line; Cold Temperature; HEK293 Cells; Humans; Male; Menthol; Pain Measurement; TRPM Cation Channels; TRPV Cation Channels; Young Adult | 2016 |
Select noxious stimuli induce changes on corneal nerve morphology.
Topics: Animals; Capsaicin; Cornea; Disease Models, Animal; Imaging, Three-Dimensional; Immunohistochemistry; Irritants; Male; Menthol; Microscopy, Confocal; Nociceptors; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic | 2017 |
Sensory effects of transient receptor potential channel agonists on whole mouth saliva extensional rheology.
Topics: Acrolein; Adult; Capsaicin; Female; Flavoring Agents; Healthy Volunteers; Humans; Male; Menthol; Mouth; Mouthwashes; Rheology; Saliva; Sensory System Agents; Transient Receptor Potential Channels; Young Adult | 2017 |
Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons.
Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Chloroquine; Chronic Disease; Cryotherapy; Disease Models, Animal; Histamine; Humans; Menthol; Mice; Mice, Inbred C57BL; Mice, Knockout; Pruritus; Sensory Receptor Cells; Skin; Treatment Outcome; TRPM Cation Channels | 2018 |
Effect of Capsaicin and Other Thermo-TRP Agonists on Thermoregulatory Processes in the American Cockroach.
Topics: Animals; Capsaicin; Cockroaches; Isothiocyanates; Menthol; Temperature; Thymol; TRPV Cation Channels | 2018 |
Intermittent sprint performance in the heat is not altered by augmenting thermal perception via L-menthol or capsaicin mouth rinses.
Topics: Adult; Capsaicin; Exercise; Hot Temperature; Humans; Male; Menthol; Mouthwashes; Perception; Physical Exertion; Skin Temperature; Thermosensing; Young Adult | 2019 |
Oral thermosensing by murine trigeminal neurons: modulation by capsaicin, menthol and mustard oil.
Topics: Animals; Calcium-Binding Proteins; Capsaicin; Cold Temperature; Female; Green Fluorescent Proteins; Hot Temperature; Male; Menthol; Mice; Mustard Plant; Neurons; Plant Oils; Thermosensing; Transient Receptor Potential Channels; Trigeminal Nerve | 2019 |
Dry eye sensitizes cool cells to capsaicin-induced changes in activity via TRPV1.
Topics: Animals; Capsaicin; Cornea; Dry Eye Syndromes; Electrophysiological Phenomena; Lacrimal Apparatus; Menthol; Neurons, Afferent; Rats; Sensory System Agents; Trigeminal Ganglion; TRPM Cation Channels; TRPV Cation Channels | 2019 |
Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction.
Topics: Capsaicin; Cyanides; Drug Discovery; Menthol; Molecular Structure; TRPM Cation Channels; TRPV Cation Channels | 2019 |
Anatomical stability of human fungiform papillae and relationship with oral perception measured by salivary response and intensity rating.
Topics: Adult; Capsaicin; Female; Humans; Male; Menthol; Saliva; Salivary Proteins and Peptides; Sucrose; Taste Buds; Taste Perception; Young Adult | 2019 |
Lacrimal gland excision in male and female mice causes ocular pain and anxiety-like behaviors.
Topics: Animals; Anxiety; Capsaicin; Dry Eye Syndromes; Eye Pain; Female; Lacrimal Apparatus; Male; Menthol; Mice, Inbred C57BL; Pain Measurement; Sex Characteristics | 2020 |
Combination of TRP channel dietary agonists induces energy expending and glucose utilizing phenotype in HFD-fed mice.
Topics: Acrolein; Animals; Capsaicin; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Menthol; Mice; Mice, Inbred C57BL; Phenotype; Transient Receptor Potential Channels | 2022 |
Combining Topical Agonists With the Recording of Event-Related Brain Potentials to Probe the Functional Involvement of TRPM8, TRPA1 and TRPV1 in Heat and Cold Transduction in the Human Skin.
Topics: Animals; Brain; Capsaicin; Cold Temperature; Evoked Potentials; Hot Temperature; Humans; Membrane Proteins; Menthol; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels | 2022 |
Participation of Potential Transient Receptors in the Antinociceptive Effect of Pharmacopuncture.
Topics: Acupuncture; Analgesics; Animals; Capsaicin; Male; Menthol; Neuralgia; Pain Measurement; Rats; Rats, Wistar | 2022 |
A Comparative Study on the Effect of Acute Pharyngeal Stimulation with TRP Agonists on the Biomechanics and Neurophysiology of Swallow Response in Patients with Oropharyngeal Dysphagia.
Topics: Acrolein; Acyclic Monoterpenes; Alkaloids; Benzodioxoles; Biomechanical Phenomena; Capsaicin; Deglutition; Deglutition Disorders; Humans; Menthol; Piperidines; Polyunsaturated Alkamides; Retrospective Studies; Zinc | 2022 |
Separation of Nonivamide and Capsaicin by Ultrahigh-Performance Liquid Chromatography for Routine Analysis of Capsaicinoids in Capsicum Products.
Topics: Camphor; Capsaicin; Capsicum; Chromatography, High Pressure Liquid; Chromatography, Liquid; Menthol; Vegetables; Water | 2023 |
Protective effects of Capsicum fruits and their constituents on damage in TNF-α-stimulated human dermal fibroblasts.
Topics: Anti-Inflammatory Agents; Antioxidants; Camphor; Capsaicin; Capsicum; Fruit; Humans; Matrix Metalloproteinase 1; Menthol; Procollagen; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vegetables | 2023 |
In vitro Evaluation of Anti-Inflammatory Activity of "Habanero" Chili Pepper (Capsicum chinense) Seeds Extracts Pretreated with Cellulase.
Topics: Animals; Anti-Inflammatory Agents; Camphor; Capsaicin; Capsicum; Cellulases; Chromatography, Liquid; Fruit; Menthol; Mice; Phenols; Plant Extracts; Seeds; Tandem Mass Spectrometry | 2023 |
Long-term follow-up of surgical treatment of thyroid-associated orbitopathy restrictive strabismus.
Topics: Capsaicin; Diplopia; Follow-Up Studies; Graves Ophthalmopathy; Humans; Menthol; Retrospective Studies; Strabismus; Treatment Outcome | 2022 |
Working hours, side work, and depressive symptoms in physicians: A nationwide cross-sectional study in Japan.
Topics: Capsaicin; Cross-Sectional Studies; Depression; Employment; Humans; Japan; Menthol; Physicians | 2022 |
Transient Receptor Potential (TRP) based polypharmacological combination stimulates energy expending phenotype to reverse HFD-induced obesity in mice.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Capsaicin; Diet, High-Fat; Energy Metabolism; Menthol; Mice; Mice, Inbred C57BL; Obesity; Phenotype; Quality of Life | 2023 |
Effects of endogenous capsaicin stress and fermentation time on the microbial succession and flavor compounds of chili paste (a Chinese fermented chili pepper).
Topics: Camphor; Capsaicin; Capsicum; Fermentation; Menthol | 2023 |
Factors explaining individual differences in the oral perception of capsaicin, l-menthol, and aluminum ammonium sulfate.
Topics: Capsaicin; Female; Humans; Individuality; Male; Menthol; Perception | 2023 |
Enhanced detection rate of Mycoplasma genitalium in urine overtime by transcription-mediated amplification in comparison to real-time PCR.
Topics: Ambulatory Care Facilities; Body Fluids; Capsaicin; Humans; Menthol; Mycoplasma genitalium; Real-Time Polymerase Chain Reaction | 2023 |
Evaluation of maxillary canine and molar movement during the first phase of extraction space closure: a multilevel analysis.
Topics: Capsaicin; Cuspid; Humans; Menthol; Molar; Multilevel Analysis | 2023 |
Long working hours and risk of hypertensive intracerebral haemorrhage among Japanese workers claiming compensation for overwork-related intracerebral haemorrhage: an unmatched case-control study.
Topics: Brain; Capsaicin; Case-Control Studies; Cerebral Hemorrhage; East Asian People; Humans; Intracranial Hemorrhage, Hypertensive; Menthol; Occupational Health | 2023 |