menthol and capsaicin

menthol has been researched along with capsaicin in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (6.14)18.2507
2000's40 (35.09)29.6817
2010's48 (42.11)24.3611
2020's19 (16.67)2.80

Authors

AuthorsStudies
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J1
Nilius, B; Owsianik, G; Talavera, K; Voets, T1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ann, J; Blumberg, PM; Choi, K; Esch, TE; Ha, HJ; Hwang, SW; Kim, H; Kim, HS; Kim, M; Kim, YH; Lee, J; Pearce, LV; Thorat, SA; Turcios, NA1
Erickson, RP; Simon, SA; Wang, Y1
Cliff, MA; Green, BG1
Kuwahara, M; Sekizawa, S; Sugano, S; Tsubone, H1
Grattan, TJ; Laude, EA; Morice, AH; Wright, CE1
Bowen, WP; Grattan, TJ; Morice, AH; Wright, CE1
Kanamaru, A; Kojima, K; Kuwahara, M; Mutoh, T; Nishimura, R; Sasaki, N; Tsubone, H1
Fall, M; Geirsson, G; Lindström, S1
Green, BG; McAuliffe, BL1
Clapham, DE1
Kahl, U1
Lane, HW; Rice, BL; Rose, MS; Vickers, ZM1
Babes, A; Pluteanu, F; Reid, G1
Green, BG; Schullery, MT1
Baccei, ML; Bardoni, R; Fitzgerald, M1
Arsenault, J; Dorion, D; Praud, JP; Reix, P; Roulier, S1
Anand, P1
Jordt, SE; Julius, D; McKemy, DD1
Droogmans, G; Flockerzi, V; Janssens, A; Nilius, B; Voets, T; Wissenbach, U1
Babes, A; Reid, G; Zorzon, D1
Barritt, GJ; Zhang, L1
Hayashi, F; Mizuyachi, K; Niki, T; Tsukimi, Y; Yamasaki, T1
Green, BG1
Akirav, C; Alvarez-Reeves, M; George, P; Green, BG1
Chen, M; Gu, JG; Ling, J; Xing, H1
Brauchi, S; Latorre, R; Orta, G; Rosenmann, E; Salazar, M1
Dubin, AE; Hwang, SW; Macpherson, LJ; Miyamoto, T; Patapoutian, A; Story, GM1
Katsura, H; Noguchi, K; Sakagami, M; Tsuzuki, K1
Kalantzis, A; Loescher, AR; Robinson, PP1
Alqatari, M; Ernfors, P; Hjerling-Leffler, J; Koltzenburg, M1
Albin, KC; Carstens, E; Carstens, MI1
Horie, S; Matsumoto, K; Nakamura, T; Penuelas, A; Tashima, K; Tsuchiya, S; Yano, S1
Endo, T; Hayashi, S; Kubo, Y; Nakamura, E; Takeuchi, K1
Chen, M; Gu, JG; Ling, J; Tan, W; Xing, H1
Dhaka, A; Earley, TJ; Patapoutian, A; Watson, J1
Harada, K; Ikeda, S; Kamikawa, Y; Kawahira, K; Nomoto, Y; Ohwatashi, A; Yoshida, A1
Reilly, CA; Sabnis, AS; Shadid, M; Yost, GS1
Engel, S; Lee, BB; McLachlan, E; Wasner, G1
Alenmyr, L; Greiff, L; Högestätt, ED; Zygmunt, PM1
Flühr, K; Lötsch, J; Neddermeyer, TJ1
Dhaka, A; Mandadi, S; McKemy, DD; Nakanishi, ST; Patapoutian, A; Takashima, Y; Whelan, PJ1
Bautista, DM; Gerhold, KA1
Fernández-Ballester, G; Ferrer-Montiel, A; Malkia, A; Pertusa, M; Viana, F1
Crawford, DC; Gereau, RW; Mennerick, S; Moulder, KL; Story, GM1
Cahusac, PM1
Filippov, IB; Kuliieva, IeM; Prevarskaia, N; Shuba, IaM; Skryma, R; Vladymyrova, IA1
Patel, T; Yosipovitch, G2
Basbaum, AI; Bráz, JM1
Gu, J; Sarria, I1
Ebihara, S; Ebihara, T; Kohzuki, M; Sumi, Y1
Carstens, E; Carstens, MI; Cheung, S; Furrer, S; Ivanov, MA; Klein, AH; Sawyer, CM; Simons, CT; Slack, JP; Zanotto, KL1
Beltrán, C; Darszon, A; De Blas, G; de la Vega-Beltrán, JL; Gibbs, GM; Martínez-López, P; Monroy, E; O'Bryan, MK; Orta, G; Treviño, CL1
About, I; Curtis, TM; El Karim, IA; Irwin, CR; Killough, SA; Linden, GJ; Lundy, FT; McGahon, MK1
Anand, P; Roberts, K; Shenoy, R1
Dong, L; Li, Q; Luo, P; Rong, W; Sun, B; Zhou, Y1
Baggio, CH; Freitas, CS; Iacomini, M; Marcon, R; Marques, MC; Rae, GA; Santos, AR; Sassaki, GL; Smiderle, FR; Werner, MF1
Adams, E; D'Autry, W; Dewever, C; Forier, M; Hoogmartens, J; Pauwels, J; Van den Bossche, L; Van Schepdael, A; Vandenwaeyenberg, S; Wolfs, K1
Isami, K; Kaneko, S; Nakagawa, T; Nakamura, S; Shirakawa, H; Zhao, M1
Hayashi, N; Kashima, H1
Bende, M; Millqvist, E; Ternesten-Hasséus, E1
Baad-Hansen, L; List, T; Lu, S; Svensson, P; Zhang, Z1
Keast, JR; O'Mullane, LM; Osborne, PB1
Gu, JG; Ling, JX; Xu, GY; Zuo, X1
Alpizar, YA; Radwan, A; Radwan, I; Sanchez, A; Talavera, K; Voets, T1
Saito, M1
Horie, S; Takayama, H; Terada, Y; Tominaga, M; Uchida, K; Watanabe, T1
Barkin, RL1
Anderson, EM; Caudle, RM; Jenkins, AC; Neubert, JK1
Carstens, E; Carstens, MI; Davoodi, A; Joe, CL; Klein, AH; Takechi, K1
Ando, T; Baad-Hansen, L; Naganawa, T; Svensson, P1
Andersen, HH; Arendt-Nielsen, L; Gazerani, P; Nikbakht, A; Poulsen, JN; Uchida, Y1
Mahns, DA; Nagi, SS; Samour, MS1
Drummond, PD; Finch, PM1
Baad-Hansen, L; Lu, S; Svensson, P; Zhang, Z1
Aicher, SA; Hegarty, DM; Hermes, SM1
Andrade, VA; Araujo, IG; Barbosa-Filho, JM; Braz, AL; Chaves, CG; Correia, Nde A; Cruz, Jdos S; de Albuquerque, JG; de Almeida, MM; de Medeiros, IA; Gomes, MA; Leite, Mde F; Nunes, XP; Pesquero, JL; Pinho-da-Silva, L; Silva, DF1
Fujita, F; Matsui, H; Shimada, T; Suzuki, Y; Takaishi, M; Tominaga, M; Uchida, K1
Ebihara, S; Ebihara, T; Izukura, H; Miyagi, M; Okuni, I; Sekiya, H1
Metz, M; Staubach, P1
Aicher, SA; Hegarty, DM; Hermes, SM; Yang, K1
Paisley, P; Serpell, M1
Carpenter, GH; Hans, J; Houghton, JW; Ley, JP; Pesaro, M; Proctor, G1
Borad, N; Catich, E; Li, N; McKemy, DD; Ongun, S; Palkar, R; Sarkisian, A1
Cao, T; Tey, HL; Yosipovitch, G1
Alhaddad, M; Boen, M; Goldman, MP; Guiha, I; Wu, DP1
Jankowska, M; Kletkiewicz, H; Maliszewska, J; Rogalska, J; Stankiewicz, M1
Gibson, OR; Hayes, M; Wrightson, JG1
Breza, JM; Chaudhari, N; Leijon, SCM; Neves, AF; Roper, SD; Simon, SA1
Lötsch, J; Weyer-Menkhoff, I1
Fujii, N; Hatta, A; Kurose, M; Meng, ID; Okamoto, K; Sullivan, C; Yamamura, K1
Galli, U; Genazzani, AA; Griglio, A; Pirali, T; Serafini, M; Tron, GC1
Carpenter, GH; Gardner, A1
Ando, H; Hossain, MZ; Kitagawa, J; Unno, S1
Demers, D; Denis, TE; Kalliel, JR; Mecum, NE; Meng, ID; Sullivan, CE1
Bhadada, SK; Bhunia, RK; Bishnoi, M; Kaur, J; Khare, P; Kondepudi, KK; Kuhad, A; Kumar, V; Mahajan, N; Shafi, S1
Courtin, AS; Mouraux, A1
Argôlo, IPR; Parisi, JR; Silva, JRTD; Silva, MLD1
Alvarez-Berdugo, D; Clavé, P; Ortega, O; Rofes, L; Tomsen, N1
Pointer, B; Rainville, P; Yang, J1
Choi, J; Jang, L; Lee, S1
Antunes-Ricardo, M; Cortés-Ferré, HE; Guerrero-Analco, JA; Gutiérrez-Uribe, JA; Martínez-Avila, M; Monribot-Villanueva, JL1
Fossataro, C; Mattei, R; Pafundi, PC; Salerni, A; Savino, G1
Imamura, S; Ishimaru, T; Kido, M; Kimori, K; Matsumoto, K; Nakashima, Y; Nakayasu, A; Okawara, M; Yoshikawa, T1
Bhunia, RK; Bishnoi, M; Kaur, J; Kaur, S; Kondepudi, KK; Kuhad, A; Kumar, V; Singh, DP1
Cai, Y; Chen, J; Li, H; Liu, B; Mei, Y; Shi, Q; Tang, H; Wang, X; Yang, M; Zhao, N1
Heffernan, SM; Jeffries, O; John, K; Page, J; Peel, J; Tallent, J; Waldron, M1
Aisala, H; Hoppu, U; Puputti, S; Roukka, S; Sandell, M; Seppä, L1
Adriaens, N; Bruisten, SM; Pennekamp, AM; van Dam, AP1
Gandini Júnior, LG; Jacob, HB; Kim, KB; Monini, ADC; Schneider, PP1
Morita, Y; Takahashi, M; Yoshikawa, T1

Reviews

14 review(s) available for menthol and capsaicin

ArticleYear
Sensing with TRP channels.
    Nature chemical biology, 2005, Volume: 1, Issue:2

    Topics: Animals; Humans; Ligands; Models, Biological; Phylogeny; Temperature; Transient Receptor Potential Channels

2005
The bladder cooling reflex and the use of cooling as stimulus to the lower urinary tract.
    The Journal of urology, 1999, Volume: 162, Issue:6

    Topics: Adult; Animals; Capsaicin; Child; Cold Temperature; Humans; Infant; Menthol; Muscle, Smooth; Physical Stimulation; Reflex; Urinary Bladder; Urinary Bladder Diseases

1999
Lessons from peppers and peppermint: the molecular logic of thermosensation.
    Current opinion in neurobiology, 2003, Volume: 13, Issue:4

    Topics: Animals; Capsaicin; Capsicum; Humans; Mentha piperita; Menthol; Plant Oils; Thermoreceptors

2003
Molecular and cellular mechanisms of trigeminal chemosensation.
    Annals of the New York Academy of Sciences, 2009, Volume: 1170

    Topics: Amides; Animals; Capsaicin; Humans; Menthol; Mustard Plant; Plant Oils; Somatosensory Cortex; Taste Perception; Trigeminal Nerve

2009
Therapy of pruritus.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:10

    Topics: Adrenal Cortex Hormones; Antidepressive Agents; Antipsychotic Agents; Capsaicin; Emollients; Histamine Antagonists; Humans; Immunologic Factors; Menthol; Pruritus

2010
The management of chronic pruritus in the elderly.
    Skin therapy letter, 2010, Volume: 15, Issue:8

    Topics: Administration, Oral; Administration, Topical; Aged; Antipruritics; Cannabinoids; Capsaicin; Central Nervous System Agents; Chronic Disease; Emollients; Glucocorticoids; Histamine Antagonists; Humans; Immunologic Factors; Menthol; Phototherapy; Pruritus; Salicylic Acid; Skin Aging

2010
Brown adipose tissue as a therapeutic target for human obesity.
    Obesity research & clinical practice, 2013, Volume: 7, Issue:6

    Topics: Adipose Tissue, Brown; Age Factors; Animals; Capsaicin; Capsicum; Cold Temperature; Energy Metabolism; Environmental Exposure; Fluorodeoxyglucose F18; Humans; Ion Channels; Menthol; Mitochondrial Proteins; Obesity; Phytotherapy; Plant Extracts; Positron-Emission Tomography; Radiopharmaceuticals; Thermogenesis; Transient Receptor Potential Channels; Uncoupling Protein 1

2013
The pharmacology of topical analgesics.
    Postgraduate medicine, 2013, Volume: 125, Issue:4 Suppl 1

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Camphor; Capsaicin; Cryotherapy; Cyclooxygenase Inhibitors; Humans; Hyperthermia, Induced; Irritants; Menthol; Pain Management; Salicylates

2013
Topical treatment in pain medicine: from ancient remedies to modern usage.
    Pain management, 2015, Volume: 5, Issue:5

    Topics: Administration, Cutaneous; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Clonidine; Cocaine; Epidermis; History, 18th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Ketamine; Mandragora; Menthol; Nociception; Pain Management; Plant Extracts

2015
Chemical Senses Affecting Cough and Swallowing.
    Current pharmaceutical design, 2016, Volume: 22, Issue:15

    Topics: Acids; Angiotensin-Converting Enzyme Inhibitors; Animals; Capsaicin; Cigarette Smoking; Cough; Deglutition; Humans; Menthol; Nicotine; Theophylline

2016
Itch Management: Topical Agents.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Antipruritics; Camphor; Cannabinoid Receptor Agonists; Capsaicin; Chronic Disease; Dermatologic Agents; Glycerol; Humans; Menthol; Narcotic Antagonists; Pruritus; Skin Care; Sodium Chloride; Urea

2016
The role of topiceuticals in cancer pain.
    Current opinion in supportive and palliative care, 2017, Volume: 11, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Cancer Pain; Capsaicin; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Humans; Lidocaine; Menthol; Neuralgia; Pain Management; Pain Measurement

2017
Chronic Pruritus in the Geriatric Population.
    Dermatologic clinics, 2018, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Antidepressive Agents; Antipruritics; Calcineurin Inhibitors; Capsaicin; Cholestasis; Chronic Disease; Emollients; Histamine; Histamine Antagonists; Humans; Kidney Failure, Chronic; Liver Diseases; Menthol; Nervous System Diseases; Palliative Care; Paraneoplastic Syndromes; Pruritus; Skin Aging; Skin Diseases; Urticaria

2018
Targeting Chemosensory Ion Channels in Peripheral Swallowing-Related Regions for the Management of Oropharyngeal Dysphagia.
    International journal of molecular sciences, 2020, Aug-27, Volume: 21, Issue:17

    Topics: Animals; Capsaicin; Citric Acid; Deglutition Disorders; Humans; Ion Channels; Menthol; Molecular Targeted Therapy; Neuronal Plasticity; Randomized Controlled Trials as Topic; Sensory System Agents

2020

Trials

11 trial(s) available for menthol and capsaicin

ArticleYear
Sensitization and desensitization to capsaicin and menthol in the oral cavity: interactions and individual differences.
    Physiology & behavior, 1996, Volume: 59, Issue:3

    Topics: Adult; Capsaicin; Drug Interactions; Female; Humans; Individuality; Male; Menthol; Mouth; Nerve Fibers; Stimulation, Chemical; Time Factors

1996
Menthol desensitization of capsaicin irritation. Evidence of a short-term anti-nociceptive effect.
    Physiology & behavior, 2000, Volume: 68, Issue:5

    Topics: Administration, Topical; Adult; Antipruritics; Capsaicin; Drug Administration Schedule; Female; Humans; Male; Menthol; Nerve Fibers; Pain Measurement; Reaction Time; Stimulation, Chemical; Time Factors; Tongue

2000
Modulation of oral heat and cold pain by irritant chemicals.
    Chemical senses, 2008, Volume: 33, Issue:1

    Topics: Acrolein; Adolescent; Adult; Capsaicin; Cold Temperature; Female; Hot Temperature; Humans; Irritants; Male; Menthol; Middle Aged; Mustard Plant; Nociceptors; Plant Oils; Temperature; Thermosensing; Tongue; Transient Receptor Potential Channels

2008
Capsaicin or menthol sensitization induces quantitative but no qualitative changes to thermal and mechanical pain thresholds.
    The Clinical journal of pain, 2009, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Antipruritics; Capsaicin; Female; Humans; Hyperalgesia; Male; Menthol; Middle Aged; Pain Measurement; Pain Threshold; Physical Stimulation; Young Adult

2009
Facial skin blood flow responses to irritant stimuli in the oral cavity.
    Autonomic neuroscience : basic & clinical, 2013, Volume: 174, Issue:1-2

    Topics: Adult; Capsaicin; Dose-Response Relationship, Drug; Face; Female; Flavoring Agents; Humans; Irritants; Japan; Kinetics; Male; Menthol; Mouth Mucosa; Pain Measurement; Regional Blood Flow; Sensory System Agents; Skin; Young Adult

2013
Inhalation of menthol reduces capsaicin cough sensitivity and influences inspiratory flows in chronic cough.
    Respiratory medicine, 2013, Volume: 107, Issue:3

    Topics: Administration, Inhalation; Adult; Aged; Antitussive Agents; Capsaicin; Chronic Disease; Cough; Double-Blind Method; Female; Humans; Inhalation; Irritants; Male; Menthol; Middle Aged; Spirometry

2013
Somatosensory profiling of intra-oral capsaicin and menthol in healthy subjects.
    European journal of oral sciences, 2013, Volume: 121, Issue:1

    Topics: Administration, Topical; Adult; Analysis of Variance; Capsaicin; Cross-Over Studies; Double-Blind Method; Facial Pain; Female; Gingiva; Humans; Male; Menthol; Models, Biological; Pain Measurement; Pain Threshold; Statistics, Nonparametric

2013
Spatial and Temporal Effects of Capsaicin and Menthol on Intraoral Somatosensory Sensitivity.
    Journal of oral & facial pain and headache, 2015,Summer, Volume: 29, Issue:3

    Topics: Adult; Capsaicin; Cross-Over Studies; Double-Blind Method; Female; Gingiva; Humans; Male; Menthol; Pain Threshold; Sensation; Sensory System Agents; Spatio-Temporal Analysis

2015
A Single Site, Open Label Clinical Trial, Evaluating the Duration, Efficacy, and Safety of a Novel Lip Plumper.
    Journal of drugs in dermatology : JDD, 2018, Sep-01, Volume: 17, Issue:9

    Topics: Administration, Cutaneous; Adult; Capsaicin; Cinnamomum zeylanicum; Cosmetic Techniques; Dermal Fillers; Drug Compounding; Female; Humans; Lip; Male; Menthol; Middle Aged; Prospective Studies; Skin Aging; Treatment Outcome; Viscoelastic Substances; Young Adult

2018
TRPA1 Sensitization Produces Hyperalgesia to Heat but not to Cold Stimuli in Human Volunteers.
    The Clinical journal of pain, 2019, Volume: 35, Issue:4

    Topics: Acrolein; Adult; Capsaicin; Cold Temperature; Cross-Over Studies; Female; Healthy Volunteers; Hot Temperature; Humans; Hyperalgesia; Male; Menthol; Neuralgia; Pain Threshold; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels; Young Adult

2019
Topical application of isolated menthol and combined menthol-capsaicin creams: Exercise tolerance, thermal perception, pain, attentional focus and thermoregulation in the heat.
    European journal of sport science, 2023, Volume: 23, Issue:10

    Topics: Adult; Body Temperature Regulation; Capsaicin; Cross-Over Studies; Exercise Tolerance; Female; Hot Temperature; Humans; Male; Menthol; Pain; Pain Perception; Thermosensing

2023

Other Studies

89 other study(ies) available for menthol and capsaicin

ArticleYear
Expanding the ChemGPS chemical space with natural products.
    Journal of natural products, 2005, Volume: 68, Issue:7

    Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship

2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic.
    Journal of medicinal chemistry, 2020, 01-09, Volume: 63, Issue:1

    Topics: Analgesics; Animals; Capsaicin; CHO Cells; Cricetulus; Drug Discovery; Hyperalgesia; Mice, Inbred ICR; Neuralgia; Phenylurea Compounds; Swine; Thiazoles; TRPV Cation Channels

2020
Selectivity of lingual nerve fibers to chemical stimuli.
    The Journal of general physiology, 1993, Volume: 101, Issue:6

    Topics: Ammonium Chloride; Animals; Calcium Chloride; Capsaicin; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Lanthanum; Lingual Nerve; Mechanoreceptors; Menthol; Nerve Fibers; Neural Conduction; Nicotine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium Chloride; Temperature; Tongue

1993
Nasal receptors responding to cold and l-menthol airflow in the guinea pig.
    Respiration physiology, 1996, Volume: 103, Issue:3

    Topics: Action Potentials; Animals; Antipruritics; Capsaicin; Cold Temperature; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Male; Menthol; Nasal Cavity; Nerve Fibers; Neurons, Afferent; Thermoreceptors

1996
Capsaicin and neurokinin A-induced bronchoconstriction in the anaesthetised guinea-pig: evidence for a direct action of menthol on isolated bronchial smooth muscle.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Airway Resistance; Anesthesia; Animals; Bronchi; Bronchoconstriction; Calcium; Capsaicin; Guinea Pigs; In Vitro Techniques; Male; Menthol; Muscle, Smooth; Neurokinin A

1997
Identification of the L-menthol binding site in guinea-pig lung membranes.
    British journal of pharmacology, 1998, Volume: 123, Issue:3

    Topics: Animals; Benzazepines; Binding Sites; Camphor; Capsaicin; Cell Membrane; Eugenol; Guinea Pigs; In Vitro Techniques; Lung; Male; Menthol; Radioligand Assay; Tritium

1998
The posterior nasal nerve plays an important role on cardiopulmonary reflexes to nasal application of capsaicin, distilled water and l-menthol in anesthetized dogs.
    The Journal of veterinary medical science, 1999, Volume: 61, Issue:1

    Topics: Administration, Intranasal; Anesthesia; Animals; Antipruritics; Capsaicin; Dogs; Electrophysiology; Female; Heart; Lung; Male; Menthol; Nasal Cavity; Neurons, Afferent; Reflex; Water

1999
Signal transduction. Hot and cold TRP ion channels.
    Science (New York, N.Y.), 2002, Mar-22, Volume: 295, Issue:5563

    Topics: Animals; Calcium Channels; Capsaicin; Cold Temperature; Ganglia, Spinal; Hot Temperature; Ion Channel Gating; Menthol; Mice; Mouth; Signal Transduction; Skin Physiological Phenomena; Taste; Touch; Trigeminal Ganglion; TRPC Cation Channels

2002
[TRP channels--sensitive for heat and cold, capsaicin and menthol].
    Lakartidningen, 2002, May-16, Volume: 99, Issue:20

    Topics: Animals; Calcium Channels; Capsaicin; Capsicum; Cold Temperature; Hot Temperature; Humans; Ion Channels; Menthol; Sensory Receptor Cells; Taste; Thermoreceptors

2002
Simulated microgravity [bed rest] has little influence on taste, odor or trigeminal sensitivity.
    Journal of sensory studies, 2001, Volume: 16, Issue:1

    Topics: Adult; Bed Rest; Butyrates; Capsaicin; Citric Acid; Fluid Shifts; Head-Down Tilt; Humans; Male; Menthol; Odorants; Quinine; Sensory Thresholds; Smell; Sodium Chloride; Sodium Glutamate; Sucrose; Taste Threshold; Terpenes; Weightlessness Simulation

2001
A cold- and menthol-activated current in rat dorsal root ganglion neurones: properties and role in cold transduction.
    The Journal of physiology, 2002, 12-01, Volume: 545, Issue:2

    Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Capsaicin; Cold Temperature; Electrophysiology; Fluorescent Dyes; Ganglia, Spinal; Imidazoles; In Vitro Techniques; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Menthol; Nerve Growth Factor; Organic Chemicals; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium; Stereoisomerism; Thermoreceptors

2002
Stimulation of bitterness by capsaicin and menthol: differences between lingual areas innervated by the glossopharyngeal and chorda tympani nerves.
    Chemical senses, 2003, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Antipruritics; Capsaicin; Chorda Tympani Nerve; Dose-Response Relationship, Drug; Female; Glossopharyngeal Nerve; Humans; Male; Menthol; Middle Aged; Quinine; Sucrose; Taste; Time Factors; Tongue

2003
Development of nociceptive synaptic inputs to the neonatal rat dorsal horn: glutamate release by capsaicin and menthol.
    The Journal of physiology, 2003, May-15, Volume: 549, Issue:Pt 1

    Topics: Action Potentials; Afferent Pathways; Animals; Animals, Newborn; Antipruritics; Calcium; Capsaicin; Excitatory Postsynaptic Potentials; Glutamic Acid; Menthol; Nociceptors; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Drug; Rhizotomy; Synapses

2003
Effects of C fiber blockade on cardiorespiratory responses to laryngeal stimulation in concious lambs.
    Respiratory physiology & neurobiology, 2003, Jun-12, Volume: 136, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antipruritics; Blood Pressure; Capsaicin; Carbon Dioxide; Cardiovascular Physiological Phenomena; Diaphragm; Electrocardiography; Electromyography; Goats; Heart Rate; Laryngeal Nerves; Menthol; Nerve Fibers, Unmyelinated; Reflex; Respiration; Respiratory Function Tests; Songbirds; Wakefulness; Water

2003
Capsaicin and menthol in the treatment of itch and pain: recently cloned receptors provide the key.
    Gut, 2003, Volume: 52, Issue:9

    Topics: Administration, Topical; Animals; Antipruritics; Capsaicin; Humans; Menthol; Pain; Pruritus Ani; Receptors, Drug; Thermoreceptors

2003
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.
    Nature, 2004, Aug-12, Volume: 430, Issue:7001

    Topics: Capsaicin; Cell Line; Cold Temperature; Electric Conductivity; Hot Temperature; Humans; Ion Channel Gating; Ion Channels; Ligands; Membrane Potentials; Menthol; Models, Biological; Neoplasm Proteins; Patch-Clamp Techniques; Receptors, Drug; TRPM Cation Channels

2004
Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor.
    The European journal of neuroscience, 2004, Volume: 20, Issue:9

    Topics: Animals; Ankyrins; Calcium; Calcium Channels; Calcium Signaling; Capsaicin; Cells, Cultured; Cold Temperature; Drug Synergism; Ganglia, Spinal; Ion Channels; Menthol; Mustard Plant; Neoplasm Proteins; Nerve Growth Factor; Neurons, Afferent; Plant Extracts; Plant Oils; Pyrimidinones; Rats; Thermosensing; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels

2004
Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells.
    Cancer research, 2004, Nov-15, Volume: 64, Issue:22

    Topics: Androgens; Apoptosis; Base Sequence; Calcium; Capsaicin; Cell Survival; DNA Primers; Humans; Immunohistochemistry; Ion Channels; Ion Transport; Male; Menthol; Neoplasm Proteins; Prostatic Neoplasms; Sequence Homology, Nucleic Acid; TRPM Cation Channels

2004
Cold response of the bladder in guinea pig: involvement of transient receptor potential channel, TRPM8.
    Urology, 2005, Volume: 65, Issue:2

    Topics: Afferent Pathways; Animals; Capsaicin; Cold Temperature; Female; Ganglia, Spinal; Guinea Pigs; Hexamethonium; Ion Channels; Menthol; Muscle Contraction; Nerve Fibers, Unmyelinated; Reflex; Urinary Bladder; Urination

2005
Lingual heat and cold sensitivity following exposure to capsaicin or menthol.
    Chemical senses, 2005, Volume: 30 Suppl 1

    Topics: Capsaicin; Cold Temperature; Hot Temperature; Humans; Ion Channels; Menthol; Models, Biological; Perception; Taste; Thermoreceptors; Time Factors; Tongue; TRPC Cation Channels

2005
Chemesthesis and taste: evidence of independent processing of sensation intensity.
    Physiology & behavior, 2005, Nov-15, Volume: 86, Issue:4

    Topics: Adolescent; Adult; Capsaicin; Female; Humans; Male; Menthol; Middle Aged; Psychophysics; Sodium Chloride; Stimulation, Chemical; Sucrose; Taste; Taste Buds; Thermosensing

2005
Chemical and cold sensitivity of two distinct populations of TRPM8-expressing somatosensory neurons.
    Journal of neurophysiology, 2006, Volume: 95, Issue:2

    Topics: Animals; Capsaicin; Cells, Cultured; Cold Temperature; Dose-Response Relationship, Drug; Hyperalgesia; Menthol; Neurons, Afferent; Nociceptors; Pain Threshold; Posterior Horn Cells; Rats; Sensitivity and Specificity; Tissue Distribution; TRPM Cation Channels

2006
A hot-sensing cold receptor: C-terminal domain determines thermosensation in transient receptor potential channels.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, May-03, Volume: 26, Issue:18

    Topics: Analysis of Variance; Calcium; Capsaicin; Cell Line, Transformed; Cloning, Molecular; Diagnostic Imaging; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Humans; Immunohistochemistry; Membrane Potentials; Menthol; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Temperature; Thermoreceptors; Thermosensing; Transfection; Transient Receptor Potential Channels; TRPM Cation Channels; TRPV Cation Channels

2006
More than cool: promiscuous relationships of menthol and other sensory compounds.
    Molecular and cellular neurosciences, 2006, Volume: 32, Issue:4

    Topics: Animals; Animals, Newborn; Antipruritics; Calcium; Camphor; Capsaicin; Cells, Cultured; Cricetinae; Cricetulus; Diagnostic Imaging; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Ganglia, Spinal; Keratinocytes; Membrane Potentials; Menthol; Mice; Neurons, Afferent; Patch-Clamp Techniques; Rats; Temperature; Transfection; Transient Receptor Potential Channels

2006
Differential expression of capsaicin-, menthol-, and mustard oil-sensitive receptors in naive rat geniculate ganglion neurons.
    Chemical senses, 2006, Volume: 31, Issue:7

    Topics: Animals; Ankyrins; Calcium Channels; Capsaicin; Geniculate Ganglion; Male; Menthol; Mustard Plant; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neurons; Plant Oils; Rats; Rats, Sprague-Dawley; RNA, Messenger; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels; TRPV Cation Channels

2006
Effects of capsaicin and menthol on oral thermal sensory thresholds.
    Archives of oral biology, 2007, Volume: 52, Issue:2

    Topics: Adult; Analysis of Variance; Capsaicin; Case-Control Studies; Drug Interactions; Female; Humans; Menthol; Mouth; Nerve Fibers; Perception; Sensory Thresholds; Stimulation, Chemical; Thermosensing; Time Factors

2007
Emergence of functional sensory subtypes as defined by transient receptor potential channel expression.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Mar-07, Volume: 27, Issue:10

    Topics: Acrolein; Aging; Animals; Animals, Newborn; Calcium Channels; Capsaicin; Cell Differentiation; Cell Lineage; Cells, Cultured; Cold Temperature; Embryo, Mammalian; Embryonic Development; Ganglia, Spinal; Menthol; Mice; Mice, Inbred C57BL; Neurons, Afferent; Nociceptors; Plant Lectins; RNA, Messenger; Thermoreceptors; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2007
Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine.
    European journal of pharmacology, 2007, Dec-08, Volume: 576, Issue:1-3

    Topics: Animals; Capsaicin; Disulfides; Gastrointestinal Motility; In Vitro Techniques; Intestines; Isothiocyanates; Male; Menthol; Mice; Pyrimidinones; RNA, Messenger; Sulfinic Acids; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2007
Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer.
    Inflammopharmacology, 2007, Volume: 15, Issue:5

    Topics: Animals; Ankyrins; Calcium Channel Agonists; Calcium Channels; Capsaicin; Cell Line; Epithelial Cells; Gastric Mucosa; Isothiocyanates; Menthol; Pyrimidinones; Rats; Temperature; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels; TRPV Cation Channels; Wound Healing

2007
TRPM8 mechanism of cold allodynia after chronic nerve injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Dec-12, Volume: 27, Issue:50

    Topics: Animals; Capsaicin; Cells, Cultured; Chronic Disease; Cold Temperature; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Ligation; Male; Menthol; Neurons, Afferent; Pain Measurement; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Skin; TRPM Cation Channels

2007
Visualizing cold spots: TRPM8-expressing sensory neurons and their projections.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Jan-16, Volume: 28, Issue:3

    Topics: Afferent Pathways; Animals; Antipruritics; Blood Vessels; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cold Temperature; Ganglia, Spinal; Gene Expression Regulation; Green Fluorescent Proteins; Menthol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons, Afferent; Spinal Cord; TRPM Cation Channels; TRPV Cation Channels

2008
Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats.
    Urology, 2008, Volume: 72, Issue:3

    Topics: Animals; Antipruritics; Capsaicin; Carbachol; Female; Menthol; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Temperature; TRPM Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urination

2008
Human lung epithelial cells express a functional cold-sensing TRPM8 variant.
    American journal of respiratory cell and molecular biology, 2008, Volume: 39, Issue:4

    Topics: Amino Acid Sequence; Animals; Bronchi; Capsaicin; Cell Line; Cold Temperature; Cytokines; Endoplasmic Reticulum; Epithelial Cells; Humans; Lung; Menthol; Molecular Sequence Data; Pyrazines; Pyridines; Thapsigargin; Thermoreceptors; Thermosensing; TRPM Cation Channels

2008
Residual spinothalamic tract pathways predict development of central pain after spinal cord injury.
    Brain : a journal of neurology, 2008, Volume: 131, Issue:Pt 9

    Topics: Adult; Capsaicin; Cold Temperature; Female; Histamine; Hot Temperature; Humans; Male; Menthol; Middle Aged; Nerve Fibers; Neuralgia; Nociceptors; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Prognosis; Sensation; Spinal Cord Injuries; Spinothalamic Tracts

2008
TRPV1-mediated itch in seasonal allergic rhinitis.
    Allergy, 2009, Volume: 64, Issue:5

    Topics: Acrolein; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Antipruritics; Arachidonic Acids; Calcium Channel Blockers; Calcium Channels; Capsaicin; Endocannabinoids; Humans; Menthol; Mustard Plant; Nasal Provocation Tests; Nerve Tissue Proteins; Plant Oils; Polyunsaturated Alkamides; Pruritus; Rhinitis, Allergic, Seasonal; Sensory System Agents; Severity of Illness Index; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2009
Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels.
    Neuroscience, 2009, Sep-15, Volume: 162, Issue:4

    Topics: Afferent Pathways; Animals; Animals, Newborn; Capsaicin; Cold Temperature; Hindlimb; In Vitro Techniques; Menthol; Mice; Mice, Knockout; Motor Activity; Motor Neurons; Patch-Clamp Techniques; Periodicity; Sensory System Agents; Spinal Cord; TRPM Cation Channels; TRPV Cation Channels

2009
Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.
    Molecular pain, 2009, Nov-03, Volume: 5

    Topics: Animals; Capsaicin; Clotrimazole; Cold Temperature; Humans; Imidazoles; Ion Channel Gating; Menthol; Mice; Models, Molecular; Molecular Dynamics Simulation; Mutant Proteins; Mutation; Phenotype; Pyrazines; Pyridines; Structure-Activity Relationship; TRPM Cation Channels; Tyrosine

2009
Comparative effects of heterologous TRPV1 and TRPM8 expression in rat hippocampal neurons.
    PloS one, 2009, Dec-04, Volume: 4, Issue:12

    Topics: Animals; Capsaicin; Hippocampus; Ion Channel Gating; Menthol; Neurons; Neurotransmitter Agents; Rats; Ruthenium Red; Synaptic Transmission; Tetrodotoxin; Transfection; TRPM Cation Channels; TRPV Cation Channels

2009
Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle.
    Journal of the peripheral nervous system : JPNS, 2009, Volume: 14, Issue:4

    Topics: Acrolein; Action Potentials; Animals; Ankyrins; Calcium Channels; Camphor; Capsaicin; Evoked Potentials; Hair Follicle; In Vitro Techniques; Isothiocyanates; Male; Mechanoreceptors; Menthol; Physical Stimulation; Pyrimidinones; Rats; Rats, Wistar; Ruthenium Red; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels

2009
[Modulation of the smooth muscle contractions of the rat vas deferens by TRPM8 channel agonist menthol].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2009, Volume: 55, Issue:6

    Topics: Animals; Calcium; Calcium-Transporting ATPases; Capsaicin; Carbachol; Cold Temperature; In Vitro Techniques; Intracellular Membranes; Isotonic Solutions; Male; Menthol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Muscarinic; Sarcoplasmic Reticulum; TRPM Cation Channels; Vas Deferens

2009
Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli.
    Pain, 2010, Volume: 150, Issue:2

    Topics: Activating Transcription Factor 3; Analysis of Variance; Animals; Capsaicin; Cell Count; Formaldehyde; Ganglia, Spinal; Immunohistochemistry; Menthol; Mice; Mice, Knockout; Mustard Plant; Neurons, Afferent; Nociceptors; Pain Measurement; Plant Oils; TRPV Cation Channels

2010
Menthol response and adaptation in nociceptive-like and nonnociceptive-like neurons: role of protein kinases.
    Molecular pain, 2010, Aug-20, Volume: 6

    Topics: Adaptation, Physiological; Animals; Calcium; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Female; Ganglia, Spinal; Isothiocyanates; Male; Menthol; Neurons; Nociceptors; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley

2010
Sensory stimulation to improve swallowing reflex and prevent aspiration pneumonia in elderly dysphagic people.
    Journal of pharmacological sciences, 2011, Volume: 115, Issue:2

    Topics: Activities of Daily Living; Aged; Capsaicin; Cold Temperature; Deglutition; Deglutition Disorders; Hot Temperature; Humans; Menthol; Piper nigrum; Pneumonia, Aspiration; Reflex; Sensory System Agents; Thermoreceptors; Thermosensing

2011
A tingling sanshool derivative excites primary sensory neurons and elicits nocifensive behavior in rats.
    Journal of neurophysiology, 2011, Volume: 105, Issue:4

    Topics: Acrolein; Amides; Animals; Antipruritics; Behavior, Animal; Calcium; Capsaicin; Cells, Cultured; Ganglia, Spinal; Humans; Male; Menthol; Models, Animal; Plant Extracts; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Zanthoxylum

2011
TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction.
    Journal of cellular physiology, 2011, Volume: 226, Issue:6

    Topics: Acrosome Reaction; Animals; Capsaicin; Humans; Ion Channel Gating; Male; Menthol; Mice; Mice, Knockout; Pyrazines; Pyridines; Pyrimidinones; Spermatozoa; Temperature; Testis; TRPM Cation Channels

2011
Human dental pulp fibroblasts express the "cold-sensing" transient receptor potential channels TRPA1 and TRPM8.
    Journal of endodontics, 2011, Volume: 37, Issue:4

    Topics: Acetanilides; Acrolein; Adult; Blotting, Western; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Capsaicin; Cells, Cultured; Cold Temperature; Cytophotometry; Dental Pulp; Fibroblasts; Humans; Immunohistochemistry; Membrane Proteins; Menthol; Nerve Tissue Proteins; Nociceptors; Physical Stimulation; Purines; Reverse Transcriptase Polymerase Chain Reaction; Thermosensing; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; Young Adult

2011
A novel human volunteer pain model using contact heat evoked potentials (CHEP) following topical skin application of transient receptor potential agonists capsaicin, menthol and cinnamaldehyde.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:7

    Topics: Acrolein; Adult; Capsaicin; Electroencephalography; Evoked Potentials; Female; Hot Temperature; Human Experimentation; Humans; Male; Menthol; Middle Aged; Models, Biological; Pain; Pain Measurement; Pain Threshold; Sensory System Agents; Skin; Transient Receptor Potential Channels; Young Adult

2011
Sensitivity of bronchopulmonary receptors to cold and heat mediated by transient receptor potential cation channel subtypes in an ex vivo rat lung preparation.
    Respiratory physiology & neurobiology, 2011, Aug-15, Volume: 177, Issue:3

    Topics: Acetanilides; Acrolein; Animals; Capsaicin; Cold Temperature; Hot Temperature; In Vitro Techniques; Lung; Male; Menthol; Purines; Rats; Rats, Sprague-Dawley; Respiratory System; Sensory System Agents; TRPM Cation Channels

2011
Antinociception of β-D-glucan from Pleurotus pulmonarius is possibly related to protein kinase C inhibition.
    International journal of biological macromolecules, 2012, Apr-01, Volume: 50, Issue:3

    Topics: Acid Sensing Ion Channels; Acrolein; Analgesics; Animals; Capsaicin; Enzyme Activation; Glucans; Male; Menthol; Mice; Nerve Tissue Proteins; Nociception; Pleurotus; Protein Kinase C; Protein Kinase Inhibitors; Sodium Channels; Tetradecanoylphorbol Acetate; TRPV Cation Channels

2012
Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a
    Journal of pharmaceutical and biomedical analysis, 2012, Feb-23, Volume: 60

    Topics: Analgesics, Non-Narcotic; Camphor; Capsaicin; Chromatography, Gas; Chromatography, Liquid; Liquid-Liquid Extraction; Menthol; Ointments; Pharmaceutical Preparations; Salicylates; Salicylic Acid; Sensitivity and Specificity

2012
Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice.
    Molecular pain, 2012, Jul-28, Volume: 8

    Topics: Animals; Behavior, Animal; Calcium Channels; Capsaicin; Cisplatin; Cryopyrin-Associated Periodic Syndromes; Ganglia, Spinal; Hyperalgesia; Isothiocyanates; Male; Menthol; Mice; Mice, Inbred C57BL; Nociception; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Transient Receptor Potential Channels; TRPA1 Cation Channel

2012
Co-cultures provide a new tool to probe communication between adult sensory neurons and urothelium.
    The Journal of urology, 2013, Volume: 190, Issue:2

    Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Capsaicin; Carbazoles; Coculture Techniques; Dronabinol; Female; Fura-2; Ganglia, Spinal; Immunohistochemistry; Indole Alkaloids; Indoles; Menthol; Models, Animal; Nerve Growth Factor; Phalloidine; Polyisoprenyl Phosphates; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sesquiterpenes; TRPV Cation Channels; Urothelium

2013
Operant behavioral responses to orofacial cold stimuli in rats with chronic constrictive trigeminal nerve injury: effects of menthol and capsazepine.
    Molecular pain, 2013, Jun-14, Volume: 9

    Topics: Animals; Behavior, Animal; Capsaicin; Cold Temperature; Conditioning, Operant; Facial Nerve; Facial Pain; Hyperalgesia; Male; Menthol; Neuralgia; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Trigeminal Nerve; Trigeminal Nerve Injuries; TRPM Cation Channels

2013
Lack of correlation between the amplitudes of TRP channel-mediated responses to weak and strong stimuli in intracellular Ca(2+) imaging experiments.
    Cell calcium, 2013, Volume: 54, Issue:5

    Topics: Acrolein; Animals; Calcium; Calcium Signaling; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Flow Cytometry; Fura-2; HEK293 Cells; Humans; Leucine; Menthol; Pregnenolone; Sulfonamides; Transfection; TRPV Cation Channels

2013
Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree.
    Journal of natural products, 2014, Feb-28, Volume: 77, Issue:2

    Topics: Africa; Alkaloids; Calcium; Capsaicin; Humans; Ibogaine; Menthol; Molecular Structure; Plant Bark; Pyrimidinones; Transient Receptor Potential Channels; Trees; TRPV Cation Channels; Voacanga

2014
The effects of a co-application of menthol and capsaicin on nociceptive behaviors of the rat on the operant orofacial pain assessment device.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Analysis of Variance; Animals; Capsaicin; Conditioning, Operant; Facial Pain; Male; Menthol; Nociception; Pain Measurement; Rats; Rats, Sprague-Dawley; Temperature; TRPM Cation Channels; TRPV Cation Channels

2014
Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses.
    Neuroscience, 2014, Jun-20, Volume: 271

    Topics: Acrolein; Action Potentials; Animals; Capsaicin; Cold Temperature; Cymenes; Dose-Response Relationship, Drug; Eugenol; Hot Temperature; Male; Menthol; Monoterpenes; Mustard Plant; Neurons; Neurons, Afferent; Nociceptive Pain; Plant Oils; Rats, Sprague-Dawley; Sensory System Agents; Thermosensing; Tongue; Trigeminal Ganglion; TRPV Cation Channels

2014
Influence of topical application of capsaicin, menthol and local anesthetics on intraoral somatosensory sensitivity in healthy subjects: temporal and spatial aspects.
    Experimental brain research, 2015, Volume: 233, Issue:4

    Topics: Administration, Topical; Adult; Analysis of Variance; Anesthetics, Local; Antipruritics; Capsaicin; Dose-Response Relationship, Drug; Facial Pain; Female; Healthy Volunteers; Humans; Hyperalgesia; Male; Menthol; Pain Threshold; Sensory System Agents; Time Factors; Visual Analog Scale; Young Adult

2015
Cold and L-menthol-induced sensitization in healthy volunteers--a cold hypersensitivity analogue to the heat/capsaicin model.
    Pain, 2015, Volume: 156, Issue:5

    Topics: Administration, Topical; Adult; Capsaicin; Cold Temperature; Female; Hand; Hot Temperature; Humans; Hyperalgesia; Hypersensitivity; Male; Menthol; Pain; Pain Measurement; Pain Threshold; Skin; Skin Temperature; Time Factors

2015
Cav3.2-expressing low-threshold C fibres in human hairy skin contribute to cold allodynia--a non-TRPV1- and non-TRPM8-dependent phenomenon.
    Pain, 2015, Volume: 156, Issue:8

    Topics: Adult; Benzeneacetamides; Capsaicin; Cold Temperature; Female; Humans; Male; Menthol; Myalgia; Nerve Fibers, Unmyelinated; Pain Measurement; Pain Perception; Physical Stimulation; Pyridines; Sensory Thresholds; Skin; Thermosensing; TRPM Cation Channels; TRPV Cation Channels; Young Adult

2015
Denervation of the Lacrimal Gland Leads to Corneal Hypoalgesia in a Novel Rat Model of Aqueous Dry Eye Disease.
    Investigative ophthalmology & visual science, 2015, Volume: 56, Issue:11

    Topics: Animals; Capsaicin; Cornea; Denervation; Disease Models, Animal; Dose-Response Relationship, Drug; Dry Eye Syndromes; Hypesthesia; Lacrimal Apparatus; Male; Menthol; Pain Perception; Rats; Rats, Sprague-Dawley; Tears

2015
TRPM8 Channel Activation Induced by Monoterpenoid Rotundifolone Underlies Mesenteric Artery Relaxation.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Animals; Blotting, Western; Calcium; Calcium Signaling; Capsaicin; Cold Temperature; Cytosol; In Vitro Techniques; Ion Channel Gating; Male; Menthol; Mesenteric Arteries; Monoterpenes; Pyrazines; Pyridines; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Ruthenium Red; TRPM Cation Channels; TRPV Cation Channels; Vasodilation

2015
Reciprocal effects of capsaicin and menthol on thermosensation through regulated activities of TRPV1 and TRPM8.
    The journal of physiological sciences : JPS, 2016, Volume: 66, Issue:2

    Topics: Adult; Analgesics; Capsaicin; Cell Line; Cold Temperature; HEK293 Cells; Humans; Male; Menthol; Pain Measurement; TRPM Cation Channels; TRPV Cation Channels; Young Adult

2016
Select noxious stimuli induce changes on corneal nerve morphology.
    The Journal of comparative neurology, 2017, Jun-01, Volume: 525, Issue:8

    Topics: Animals; Capsaicin; Cornea; Disease Models, Animal; Imaging, Three-Dimensional; Immunohistochemistry; Irritants; Male; Menthol; Microscopy, Confocal; Nociceptors; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic

2017
Sensory effects of transient receptor potential channel agonists on whole mouth saliva extensional rheology.
    Journal of texture studies, 2017, Volume: 48, Issue:4

    Topics: Acrolein; Adult; Capsaicin; Female; Flavoring Agents; Healthy Volunteers; Humans; Male; Menthol; Mouth; Mouthwashes; Rheology; Saliva; Sensory System Agents; Transient Receptor Potential Channels; Young Adult

2017
Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:6

    Topics: Animals; Antipruritics; Behavior, Animal; Capsaicin; Chloroquine; Chronic Disease; Cryotherapy; Disease Models, Animal; Histamine; Humans; Menthol; Mice; Mice, Inbred C57BL; Mice, Knockout; Pruritus; Sensory Receptor Cells; Skin; Treatment Outcome; TRPM Cation Channels

2018
Effect of Capsaicin and Other Thermo-TRP Agonists on Thermoregulatory Processes in the American Cockroach.
    Molecules (Basel, Switzerland), 2018, Dec-18, Volume: 23, Issue:12

    Topics: Animals; Capsaicin; Cockroaches; Isothiocyanates; Menthol; Temperature; Thymol; TRPV Cation Channels

2018
Intermittent sprint performance in the heat is not altered by augmenting thermal perception via L-menthol or capsaicin mouth rinses.
    European journal of applied physiology, 2019, Volume: 119, Issue:3

    Topics: Adult; Capsaicin; Exercise; Hot Temperature; Humans; Male; Menthol; Mouthwashes; Perception; Physical Exertion; Skin Temperature; Thermosensing; Young Adult

2019
Oral thermosensing by murine trigeminal neurons: modulation by capsaicin, menthol and mustard oil.
    The Journal of physiology, 2019, Volume: 597, Issue:7

    Topics: Animals; Calcium-Binding Proteins; Capsaicin; Cold Temperature; Female; Green Fluorescent Proteins; Hot Temperature; Male; Menthol; Mice; Mustard Plant; Neurons; Plant Oils; Thermosensing; Transient Receptor Potential Channels; Trigeminal Nerve

2019
Dry eye sensitizes cool cells to capsaicin-induced changes in activity via TRPV1.
    Journal of neurophysiology, 2019, 06-01, Volume: 121, Issue:6

    Topics: Animals; Capsaicin; Cornea; Dry Eye Syndromes; Electrophysiological Phenomena; Lacrimal Apparatus; Menthol; Neurons, Afferent; Rats; Sensory System Agents; Trigeminal Ganglion; TRPM Cation Channels; TRPV Cation Channels

2019
Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1987

    Topics: Capsaicin; Cyanides; Drug Discovery; Menthol; Molecular Structure; TRPM Cation Channels; TRPV Cation Channels

2019
Anatomical stability of human fungiform papillae and relationship with oral perception measured by salivary response and intensity rating.
    Scientific reports, 2019, 07-05, Volume: 9, Issue:1

    Topics: Adult; Capsaicin; Female; Humans; Male; Menthol; Saliva; Salivary Proteins and Peptides; Sucrose; Taste Buds; Taste Perception; Young Adult

2019
Lacrimal gland excision in male and female mice causes ocular pain and anxiety-like behaviors.
    Scientific reports, 2020, 10-14, Volume: 10, Issue:1

    Topics: Animals; Anxiety; Capsaicin; Dry Eye Syndromes; Eye Pain; Female; Lacrimal Apparatus; Male; Menthol; Mice, Inbred C57BL; Pain Measurement; Sex Characteristics

2020
Combination of TRP channel dietary agonists induces energy expending and glucose utilizing phenotype in HFD-fed mice.
    International journal of obesity (2005), 2022, Volume: 46, Issue:1

    Topics: Acrolein; Animals; Capsaicin; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Menthol; Mice; Mice, Inbred C57BL; Phenotype; Transient Receptor Potential Channels

2022
Combining Topical Agonists With the Recording of Event-Related Brain Potentials to Probe the Functional Involvement of TRPM8, TRPA1 and TRPV1 in Heat and Cold Transduction in the Human Skin.
    The journal of pain, 2022, Volume: 23, Issue:5

    Topics: Animals; Brain; Capsaicin; Cold Temperature; Evoked Potentials; Hot Temperature; Humans; Membrane Proteins; Menthol; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2022
Participation of Potential Transient Receptors in the Antinociceptive Effect of Pharmacopuncture.
    Journal of acupuncture and meridian studies, 2022, Apr-30, Volume: 15, Issue:2

    Topics: Acupuncture; Analgesics; Animals; Capsaicin; Male; Menthol; Neuralgia; Pain Measurement; Rats; Rats, Wistar

2022
A Comparative Study on the Effect of Acute Pharyngeal Stimulation with TRP Agonists on the Biomechanics and Neurophysiology of Swallow Response in Patients with Oropharyngeal Dysphagia.
    International journal of molecular sciences, 2022, Sep-15, Volume: 23, Issue:18

    Topics: Acrolein; Acyclic Monoterpenes; Alkaloids; Benzodioxoles; Biomechanical Phenomena; Capsaicin; Deglutition; Deglutition Disorders; Humans; Menthol; Piperidines; Polyunsaturated Alkamides; Retrospective Studies; Zinc

2022
Separation of Nonivamide and Capsaicin by Ultrahigh-Performance Liquid Chromatography for Routine Analysis of Capsaicinoids in Capsicum Products.
    Journal of AOAC International, 2023, Mar-01, Volume: 106, Issue:2

    Topics: Camphor; Capsaicin; Capsicum; Chromatography, High Pressure Liquid; Chromatography, Liquid; Menthol; Vegetables; Water

2023
Protective effects of Capsicum fruits and their constituents on damage in TNF-α-stimulated human dermal fibroblasts.
    Journal of the science of food and agriculture, 2023, Volume: 103, Issue:7

    Topics: Anti-Inflammatory Agents; Antioxidants; Camphor; Capsaicin; Capsicum; Fruit; Humans; Matrix Metalloproteinase 1; Menthol; Procollagen; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vegetables

2023
In vitro Evaluation of Anti-Inflammatory Activity of "Habanero" Chili Pepper (Capsicum chinense) Seeds Extracts Pretreated with Cellulase.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2023, Volume: 78, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Camphor; Capsaicin; Capsicum; Cellulases; Chromatography, Liquid; Fruit; Menthol; Mice; Phenols; Plant Extracts; Seeds; Tandem Mass Spectrometry

2023
Long-term follow-up of surgical treatment of thyroid-associated orbitopathy restrictive strabismus.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Capsaicin; Diplopia; Follow-Up Studies; Graves Ophthalmopathy; Humans; Menthol; Retrospective Studies; Strabismus; Treatment Outcome

2022
Working hours, side work, and depressive symptoms in physicians: A nationwide cross-sectional study in Japan.
    Journal of occupational health, 2022, Volume: 64, Issue:1

    Topics: Capsaicin; Cross-Sectional Studies; Depression; Employment; Humans; Japan; Menthol; Physicians

2022
Transient Receptor Potential (TRP) based polypharmacological combination stimulates energy expending phenotype to reverse HFD-induced obesity in mice.
    Life sciences, 2023, Jul-01, Volume: 324

    Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Capsaicin; Diet, High-Fat; Energy Metabolism; Menthol; Mice; Mice, Inbred C57BL; Obesity; Phenotype; Quality of Life

2023
Effects of endogenous capsaicin stress and fermentation time on the microbial succession and flavor compounds of chili paste (a Chinese fermented chili pepper).
    Food research international (Ottawa, Ont.), 2023, Volume: 168

    Topics: Camphor; Capsaicin; Capsicum; Fermentation; Menthol

2023
Factors explaining individual differences in the oral perception of capsaicin, l-menthol, and aluminum ammonium sulfate.
    Clinical and translational science, 2023, Volume: 16, Issue:10

    Topics: Capsaicin; Female; Humans; Individuality; Male; Menthol; Perception

2023
Enhanced detection rate of Mycoplasma genitalium in urine overtime by transcription-mediated amplification in comparison to real-time PCR.
    BMC infectious diseases, 2023, Sep-04, Volume: 23, Issue:1

    Topics: Ambulatory Care Facilities; Body Fluids; Capsaicin; Humans; Menthol; Mycoplasma genitalium; Real-Time Polymerase Chain Reaction

2023
Evaluation of maxillary canine and molar movement during the first phase of extraction space closure: a multilevel analysis.
    Dental press journal of orthodontics, 2023, Volume: 28, Issue:4

    Topics: Capsaicin; Cuspid; Humans; Menthol; Molar; Multilevel Analysis

2023
Long working hours and risk of hypertensive intracerebral haemorrhage among Japanese workers claiming compensation for overwork-related intracerebral haemorrhage: an unmatched case-control study.
    BMJ open, 2023, 09-22, Volume: 13, Issue:9

    Topics: Brain; Capsaicin; Case-Control Studies; Cerebral Hemorrhage; East Asian People; Humans; Intracranial Hemorrhage, Hypertensive; Menthol; Occupational Health

2023