menthol and ag 3-5

menthol has been researched along with ag 3-5 in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.17)	18.7374
1990's	0 (0.00)	18.2507
2000's	20 (43.48)	29.6817
2010's	24 (52.17)	24.3611
2020's	1 (2.17)	2.80

Authors

Authors	Studies
Nilius, B; Owsianik, G; Talavera, K; Voets, T	1
Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D	1
Brown, A; Ellis, D; Favor, DA; Kirkup, T; Klute, W; MacKenny, M; McMurray, G; Stennett, A	1
Seid, DA; Wei, ET	1
Andersson, DA; Bevan, S; Chase, HW	1
Chuang, HH; Julius, D; Neuhausser, WM	1
Babes, A; Reid, G; Zorzon, D	1
Colburn, RW; Flores, CM; Liu, Y; Lubin, ML; Qin, N; Reitz, TL; Wang, Y	1
Bandell, M; Dubin, AE; Hwang, SW; Mathur, J; Orth, A; Patapoutian, A; Petrus, MJ	1
Anderson, H; Cottrell, DF; Fleetwood-Walker, SM; Garry, EM; Mitchell, R; Proudfoot, CJ; Robertson, DC; Rosie, R	1
Barrit, G; Bavencoffe, A; Beck, B; Bidaux, G; Lemonnier, L; Prevarskaya, N; Shuba, Y; Skryma, R; Thebault, S	1
Giesecke, Y; Grötzinger, C; Hosokawa, H; Kaiser, S; Kobayashi, S; Langrehr, J; Mergler, S; Neuhaus, P; Neumann, M; Plath, T; Plöckinger, U; Strowski, MZ; Wiedenmann, B	1
De Petrocellis, L; Di Marzo, V; Moriello, AS; Orlando, P; Starowicz, K; Vivese, M	1
Bödding, M; Flockerzi, V; Wissenbach, U	1
Horie, S; Matsumoto, K; Nakamura, T; Penuelas, A; Tashima, K; Tsuchiya, S; Yano, S	1
Endo, T; Hayashi, S; Kubo, Y; Nakamura, E; Takeuchi, K	1
Hasegawa, Y; Ito, S; Kamiya, K; Kondo, M; Kume, H; Makino, Y; Shiraki, A	1
Ak, VE; G, G; H, H; Jf, D; Ma, S	1
Kühn, C; Kühn, FJ; Lückhoff, A	1
Bettinelli, I; Marconi, C; Pedretti, A; Vistoli, G	1
Jeong, HJ; Vaughan, CW; Wrigley, PJ	2
Ma, S	1
Cahusac, PM	1
Andersson, DA; Bevan, S; Gentry, C; Stoakley, N	1
Kühn, C; Kühn, FJP; Lückhoff, A; Witschas, K	1
Belmonte, C; Morenilla-Palao, C; Valero, M; Viana, F	1
Baylie, RL; Cheng, H; James, AF; Langton, PD	1
Beltrán, C; Darszon, A; De Blas, G; de la Vega-Beltrán, JL; Gibbs, GM; Martínez-López, P; Monroy, E; O'Bryan, MK; Orta, G; Treviño, CL	1
Filippov, IB; Iurkevych, A; Kuliieva, IeM; Prevarskaia, N; Shuba, IaM; Skryma, R; Vladymyrova, IA	1
Ikebe, T; Ohkubo, T; Okamoto, Y; Yamazaki, J	1
Bharate, SB; Bharate, SS	1
Mello de Queiroz, F; Pardo, LA; Stühmer, W; Valero, ML; Viana, F	1
Daimon, T; Imai, Y; Kimura, A; Kurohane, K; Narukawa, M; Sahara, Y; Watanabe, T	1
Dean, S; Doran, O; Drake, MJ; Parsons, BA; Rhodes, A; Vahabi, B	1
Babes, A; Ciobanu, AC; Dobre, C; Reid, G; Selescu, T	1
Bassetto, F; Calcagno, A; De Caro, R; De Stefani, D; Granzotto, M; Macchi, V; Petrelli, L; Porzionato, A; Rizzuto, R; Rossato, M; Silvestrin, V; Vencato, J; Vettor, R	1
Kawaguchi, A; Kuroda, H; Nishiyama, A; Sato, M; Shibukawa, Y; Shimada, M; Sobhan, U; Soya, M; Tazaki, M; Tsumura, M	1
Horie, S; Takayama, H; Terada, Y; Tominaga, M; Uchida, K; Watanabe, T	1
Babes, A; Chiritoiu, G; Cucu, D; Dima, SO; Duda, DG; Horii, A; Petrescu, S; Popescu, I; Stanica, L	1
Davis, C; Gavva, NR; Kerstein, PC; Lehto, SG; Stucky, CL; Wang, J; Wang, W; Weyer, AD; Wild, KD; Youngblood, BD; Zhang, M	1
An, X; He, M; Wang, Q; Zhang, L	1
Ohta, T; Saito, S; Takahashi, K; Tominaga, M; Yamamoto, A	1
Borysova, L; Burdyga, TV; Johnson, CD; Kustov, MV; Melanaphy, D; Watson, CA; Zholos, AV	1
Borgnia, MJ; Hsu, AL; Le, SC; Lee, SY; Yang, H; Yin, Y	1
Borgnia, MJ; Butay, KJ; Feng, S; Im, W; Lee, SY; Yin, Y; Zhang, F	1

Reviews

3 review(s) available for menthol and ag 3-5

Article	Year
Sensing with TRP channels. Nature chemical biology, 2005, Volume: 1, Issue:2 Topics: Animals; Humans; Ligands; Models, Biological; Phylogeny; Temperature; Transient Receptor Potential Channels	2005
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels	2010
Modulation of thermoreceptor TRPM8 by cooling compounds. ACS chemical neuroscience, 2012, Apr-18, Volume: 3, Issue:4 Topics: Animals; Cold Temperature; Humans; Menthol; Pyrimidinones; Thermoreceptors; Thermosensing; TRPM Cation Channels	2012

Other Studies

43 other study(ies) available for menthol and ag 3-5

Article	Year
Serendipity in drug-discovery: a new series of 2-(benzyloxy)benzamides as TRPM8 antagonists. Bioorganic & medicinal chemistry letters, 2013, Nov-15, Volume: 23, Issue:22 Topics: Animals; Benzamides; Drug Design; Drug Discovery; Humans; Rats; Structure-Activity Relationship; TRPM Cation Channels	2013
AG-3-5: a chemical producing sensations of cold. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:2 Topics: Animals; Cold Temperature; Male; Menthol; Mutagens; Pyrimidinones; Rats; Sensation	1983
TRPM8 activation by menthol, icilin, and cold is differentially modulated by intracellular pH. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jun-09, Volume: 24, Issue:23 Topics: Animals; CHO Cells; Cold Temperature; Cricetinae; Cricetulus; Electrophysiology; Fluorescent Dyes; Fura-2; Hydrogen-Ion Concentration; Ion Channels; Menthol; Neoplasm Proteins; Pyrimidinones	2004
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron, 2004, Sep-16, Volume: 43, Issue:6 Topics: Acetylcholine; Animals; Calcium; Calcium Signaling; Cell Line; Cell Membrane; Chelating Agents; Chickens; Cold Temperature; Cyclohexane Monoterpenes; Cytoplasm; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Egtazic Acid; Humans; Ion Channel Gating; Ion Channels; Membrane Potentials; Menthol; Molecular Biology; Molecular Sequence Data; Mutagenesis, Site-Directed; Neoplasm Proteins; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Calcium-Activated; Pyrimidinones; Small-Conductance Calcium-Activated Potassium Channels; Terpenes; Transfection; TRPM Cation Channels; Xenopus laevis	2004
Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor. The European journal of neuroscience, 2004, Volume: 20, Issue:9 Topics: Animals; Ankyrins; Calcium; Calcium Channels; Calcium Signaling; Capsaicin; Cells, Cultured; Cold Temperature; Drug Synergism; Ganglia, Spinal; Ion Channels; Menthol; Mustard Plant; Neoplasm Proteins; Nerve Growth Factor; Neurons, Afferent; Plant Extracts; Plant Oils; Pyrimidinones; Rats; Thermosensing; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels	2004
Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine. European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2 Topics: Action Potentials; Amino Acid Sequence; Animals; Calcium; Cell Line; Cloning, Molecular; Cold Temperature; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Fluorometry; Ganglia, Spinal; Gene Library; Humans; Menthol; Mice; Molecular Sequence Data; Mustard Plant; Oocytes; Patch-Clamp Techniques; Plant Oils; Pyrazines; Pyridines; Pyrimidinones; Rats; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Transfection; TRPM Cation Channels; Xenopus laevis	2006
High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol. Nature neuroscience, 2006, Volume: 9, Issue:4 Topics: Amino Acid Sequence; Animals; CHO Cells; Cold Temperature; Cricetinae; Gene Library; Menthol; Mice; Molecular Sequence Data; Molecular Structure; Mutagenesis; Patch-Clamp Techniques; Protein Structure, Tertiary; Pyrimidinones; TRPM Cation Channels	2006
Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain. Current biology : CB, 2006, Aug-22, Volume: 16, Issue:16 Topics: Acrolein; Amino Acids; Analgesia; Analysis of Variance; Animals; Blotting, Western; Cold Temperature; Dose-Response Relationship, Drug; Electrophysiology; Immunohistochemistry; Male; Menthol; Neuralgia; Oligonucleotides, Antisense; Pyrimidinones; Rats; Rats, Wistar; Receptors, Glutamate; Reflex; TRPM Cation Channels; Xanthenes	2006
Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. Cell calcium, 2007, Volume: 41, Issue:3 Topics: Animals; Antineoplastic Agents; Antipruritics; Biomarkers, Tumor; Cell Line, Tumor; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Ligands; Male; Menthol; Prostatic Neoplasms; Pyrimidinones; TRPM Cation Channels	2007
Transient receptor potential channel TRPM8 agonists stimulate calcium influx and neurotensin secretion in neuroendocrine tumor cells. Neuroendocrinology, 2007, Volume: 85, Issue:2 Topics: Calcium; Humans; Membrane Potentials; Menthol; Models, Biological; Neuroendocrine Tumors; Neurotensin; Pancreatic Neoplasms; Pyrimidinones; TRPM Cation Channels; Tumor Cells, Cultured	2007
Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids. Experimental cell research, 2007, May-15, Volume: 313, Issue:9 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Arachidonic Acids; Benzaldehydes; Cannabinoid Receptor Modulators; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Enzyme Inhibitors; Humans; Ion Channel Gating; Menthol; Polyunsaturated Alkamides; Pyrimidinones; Receptor, Cannabinoid, CB1; Signal Transduction; Transfection; TRPM Cation Channels	2007
Characterisation of TRPM8 as a pharmacophore receptor. Cell calcium, 2007, Volume: 42, Issue:6 Topics: Calcium Signaling; Carboxylic Acids; Cell Line; Cell Line, Tumor; Cytophotometry; Dose-Response Relationship, Drug; Gene Expression; Humans; Membrane Potentials; Menthol; Molecular Structure; Oxides; Patch-Clamp Techniques; Phosphines; Pyrimidinones; Receptors, Cytoplasmic and Nuclear; Transfection; TRPM Cation Channels	2007
Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine. European journal of pharmacology, 2007, Dec-08, Volume: 576, Issue:1-3 Topics: Animals; Capsaicin; Disulfides; Gastrointestinal Motility; In Vitro Techniques; Intestines; Isothiocyanates; Male; Menthol; Mice; Pyrimidinones; RNA, Messenger; Sulfinic Acids; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels	2007
Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer. Inflammopharmacology, 2007, Volume: 15, Issue:5 Topics: Animals; Ankyrins; Calcium Channel Agonists; Calcium Channels; Capsaicin; Cell Line; Epithelial Cells; Gastric Mucosa; Isothiocyanates; Menthol; Pyrimidinones; Rats; Temperature; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels; TRPV Cation Channels; Wound Healing	2007
Inhibition by the cold receptor agonists menthol and icilin of airway smooth muscle contraction. Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:5 Topics: Animals; Calcium; Cold Temperature; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Intracellular Fluid; Male; Menthol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Pyrimidinones; Spectrometry, Fluorescence; Thermoreceptors; Trachea	2008
Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels. Pakistan journal of pharmaceutical sciences, 2008, Volume: 21, Issue:4 Topics: Analgesics; Anilides; Animals; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Gene Transfer Techniques; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Menthol; Mice; Nerve Tissue Proteins; Pyrimidinones; Rats; Tachyphylaxis; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels; Xenopus laevis	2008
Inhibition of TRPM8 by icilin distinct from desensitization induced by menthol and menthol derivatives. The Journal of biological chemistry, 2009, Feb-13, Volume: 284, Issue:7 Topics: Antipruritics; Calcium; Calcium Channels; Cell Line; Cold Temperature; Humans; Menthol; Mutation; Nerve Tissue Proteins; Phosphatidylinositol 4,5-Diphosphate; Pyrimidinones; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels	2009
Comparative modeling of the quaternary structure for the human TRPM8 channel and analysis of its binding features. Biochimica et biophysica acta, 2009, Volume: 1788, Issue:5 Topics: Binding Sites; Biophysical Phenomena; Humans; Ion Channel Gating; Ligands; Menthol; Models, Molecular; Protein Structure, Quaternary; Protein Structure, Tertiary; Pyrimidinones; Static Electricity; TRPM Cation Channels	2009
Primary afferents with TRPM8 and TRPA1 profiles target distinct subpopulations of rat superficial dorsal horn neurones. British journal of pharmacology, 2009, Volume: 157, Issue:3 Topics: Afferent Pathways; Animals; Ankyrins; Calcium Channels; Cold Temperature; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Menthol; Patch-Clamp Techniques; Posterior Horn Cells; Pyrimidinones; Rats; Rats, Sprague-Dawley; Synaptic Transmission; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels	2009
Letter to the editor: "Is menthol- or icilin-induced vasodilation mediated by the activation of TRPM8?". American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:2 Topics: Animals; Humans; Menthol; Pyrimidinones; TRPM Cation Channels; Vasodilation	2009
Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle. Journal of the peripheral nervous system : JPNS, 2009, Volume: 14, Issue:4 Topics: Acrolein; Action Potentials; Animals; Ankyrins; Calcium Channels; Camphor; Capsaicin; Evoked Potentials; Hair Follicle; In Vitro Techniques; Isothiocyanates; Male; Mechanoreceptors; Menthol; Physical Stimulation; Pyrimidinones; Rats; Rats, Wistar; Ruthenium Red; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels	2009
The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity. Molecular pain, 2010, Jan-21, Volume: 6 Topics: Animals; Antipruritics; Cold Temperature; Dose-Response Relationship, Drug; Foot; Group VI Phospholipases A2; Hyperalgesia; Male; Menthol; Mice; Mice, Knockout; Naphthalenes; Nociceptors; Pain Measurement; Pain Threshold; Pyrimidinones; Pyrones; Rats; Rats, Wistar; Sensory Receptor Cells; Thermosensing; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels	2010
Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8. The Journal of biological chemistry, 2010, Aug-27, Volume: 285, Issue:35 Topics: Adenosine Diphosphate Ribose; Antipruritics; Calcium; Cell Line; Cold Temperature; Humans; Hydrogen Peroxide; Ion Channel Gating; Membrane Potentials; Menthol; Oxidants; Protein Structure, Tertiary; Pyrimidinones; Recombinant Fusion Proteins; TRPM Cation Channels	2010
Dissociation of μ- and δ-opioid inhibition of glutamatergic synaptic transmission in superficial dorsal horn. Molecular pain, 2010, Oct-26, Volume: 6 Topics: Animals; Calcium; Calcium Channels; Excitatory Postsynaptic Potentials; Glutamates; In Vitro Techniques; Male; Menthol; Posterior Horn Cells; Presynaptic Terminals; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Synaptic Transmission	2010
Pharmacological and functional properties of TRPM8 channels in prostate tumor cells. Pflugers Archiv : European journal of physiology, 2011, Volume: 461, Issue:1 Topics: Arginine; Calcium; Cell Line; Cell Line, Tumor; Cell Membrane; Clotrimazole; Cold Temperature; Endoplasmic Reticulum; Glycine; Humans; Male; Menthol; Prostate; Prostatic Neoplasms; Pyrazines; Pyridines; Pyrimidinones; TRPM Cation Channels	2011
Inhibition of the cardiac L-type calcium channel current by the TRPM8 agonist, (-)-menthol. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:5 Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Cold Temperature; Heart Ventricles; Male; Membrane Potentials; Menthol; Myocytes, Cardiac; Nimodipine; Patch-Clamp Techniques; Pyrimidinones; Rabbits; TRPM Cation Channels	2010
TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction. Journal of cellular physiology, 2011, Volume: 226, Issue:6 Topics: Acrosome Reaction; Animals; Capsaicin; Humans; Ion Channel Gating; Male; Menthol; Mice; Mice, Knockout; Pyrazines; Pyridines; Pyrimidinones; Spermatozoa; Temperature; Testis; TRPM Cation Channels	2011
[Comparative effects of menthol and icilin on the induced contraction of the smooth muscles of the vas deferens of normal and castrated rats]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2011, Volume: 57, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Epididymis; Male; Menthol; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Orchiectomy; Potassium Chloride; Prostate; Pyrimidinones; Rats; TRPM Cation Channels; Vas Deferens	2011
Blockade of TRPM8 activity reduces the invasion potential of oral squamous carcinoma cell lines. International journal of oncology, 2012, Volume: 40, Issue:5 Topics: Anilides; Antineoplastic Agents; Calcium Signaling; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Immunohistochemistry; Matrix Metalloproteinase 9; Membrane Potentials; Menthol; Neoplasm Invasiveness; Patch-Clamp Techniques; Pyrimidinones; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tongue Neoplasms; TRPM Cation Channels	2012
TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cells. PloS one, 2012, Volume: 7, Issue:12 Topics: Benzamides; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Humans; Ion Channels; Male; Menthol; Prostate; Prostatic Neoplasms; Pyrimidinones; Thiophenes; Transfection; TRPM Cation Channels; Wound Healing	2012
Lack of transient receptor potential melastatin 8 activation by phthalate esters that enhance contact hypersensitivity in mice. Toxicology letters, 2013, Mar-13, Volume: 217, Issue:3 Topics: Acetanilides; Animals; Calcium; CHO Cells; Cricetinae; Dermatitis, Contact; Dose-Response Relationship, Drug; Menthol; Mice; Phthalic Acids; Plasticizers; Purines; Pyrimidinones; TRPM Cation Channels; TRPV Cation Channels	2013
TRPM8 agonists modulate contraction of the pig urinary bladder. Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:7 Topics: Animals; Female; Menthol; Muscle Contraction; Pyrimidinones; Swine; TRPM Cation Channels; Urinary Bladder; Urothelium	2013
Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin. Chemical senses, 2013, Volume: 38, Issue:7 Topics: Animals; Base Sequence; Boron Compounds; Calcium; Camphor; Cells, Cultured; Chickens; Cold Temperature; Dose-Response Relationship, Drug; Electrophysiology; Ganglia, Spinal; HEK293 Cells; Humans; Male; Menthol; Molecular Sequence Data; Pyrimidinones; Rats; Rats, Wistar; Ruthenium Red; TRPM Cation Channels	2013
Human white adipocytes express the cold receptor TRPM8 which activation induces UCP1 expression, mitochondrial activation and heat production. Molecular and cellular endocrinology, 2014, Mar-05, Volume: 383, Issue:1-2 Topics: Adipocytes, White; Body Temperature Regulation; Cold Temperature; Gene Expression Regulation; Glucose; Humans; Intra-Abdominal Fat; Ion Channels; Membrane Potential, Mitochondrial; Menthol; Mitochondria; Mitochondrial Proteins; Primary Cell Culture; Pyrimidinones; Signal Transduction; Subcutaneous Fat; TRPM Cation Channels; Uncoupling Protein 1	2014
Functional expression of TRPM8 and TRPA1 channels in rat odontoblasts. PloS one, 2013, Volume: 8, Issue:12 Topics: Animals; Calcium; Calcium Signaling; Dentin; Male; Menthol; Odontoblasts; Pyrimidinones; Rats; Rats, Wistar; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels	2013
Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree. Journal of natural products, 2014, Feb-28, Volume: 77, Issue:2 Topics: Africa; Alkaloids; Calcium; Capsaicin; Humans; Ibogaine; Menthol; Molecular Structure; Plant Bark; Pyrimidinones; Transient Receptor Potential Channels; Trees; TRPV Cation Channels; Voacanga	2014
Characterization of functional transient receptor potential melastatin 8 channels in human pancreatic ductal adenocarcinoma cells. Pancreas, 2014, Volume: 43, Issue:5 Topics: Adenocarcinoma; Benzamides; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; HEK293 Cells; Humans; Immunohistochemistry; Membrane Potentials; Membrane Proteins; Menthol; Pancreatic Neoplasms; Patch-Clamp Techniques; Pyrimidinones; RNA Interference; Thiophenes; TRPM Cation Channels	2014
AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. Naunyn-Schmiedeberg's archives of pharmacology, 2015, Volume: 388, Issue:4 Topics: Action Potentials; Animals; Behavior, Animal; Blood Pressure; Brain; Calcium; CHO Cells; Cold Temperature; Cricetinae; Cricetulus; Freund's Adjuvant; Humans; Hyperalgesia; Male; Menthol; Mice, Inbred C57BL; Naphthyridines; Pain; Pyrimidinones; Rats; Rats, Sprague-Dawley; Sciatic Nerve; TRPM Cation Channels	2015
Activation of Cold-Sensitive Channels TRPM8 and TRPA1 Inhibits the Proliferative Airway Smooth Muscle Cell Phenotype. Lung, 2016, Volume: 194, Issue:4 Topics: Actins; Airway Remodeling; Animals; Asthma; Bronchi; Calcium Channel Agonists; Cell Movement; Cell Proliferation; Cold Temperature; Disease Models, Animal; Female; Matrix Metalloproteinase 2; Menthol; Microfilament Proteins; Muscle Contraction; Muscle Proteins; Myocytes, Smooth Muscle; p21-Activated Kinases; p38 Mitogen-Activated Protein Kinases; Phenotype; Platelet-Derived Growth Factor; Pyrimidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Trachea; TRPA1 Cation Channel; TRPM Cation Channels	2016
Two different avian cold-sensitive sensory neurons: Transient receptor potential melastatin 8 (TRPM8)-dependent and -independent activation mechanisms. Neuropharmacology, 2016, Volume: 111 Topics: Anilides; Animals; Avian Proteins; Calcium Signaling; Chickens; Cold Temperature; Ganglia, Spinal; HEK293 Cells; Humans; Menthol; Pyrimidinones; Thermoreceptors; Thermosensing; Transient Receptor Potential Channels; TRPM Cation Channels	2016
Ion channel mechanisms of rat tail artery contraction-relaxation by menthol involving, respectively, TRPM8 activation and L-type Ca2+ channel inhibition. American journal of physiology. Heart and circulatory physiology, 2016, 12-01, Volume: 311, Issue:6 Topics: Anilides; Animals; Antipruritics; Arteries; Calcium Channels, L-Type; Calcium Signaling; Immunohistochemistry; Menthol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pyrimidinones; Rats; Tail; TRPM Cation Channels; Vasoconstriction; Vasodilation	2016
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel. Science (New York, N.Y.), 2019, 03-01, Volume: 363, Issue:6430 Topics: Animals; Binding Sites; Calcium; Cold Temperature; Cryoelectron Microscopy; Membrane Lipids; Menthol; Models, Molecular; Phosphatidylinositol 4,5-Diphosphate; Protein Structure, Tertiary; Pyrimidinones; Songbirds; TRPM Cation Channels	2019
Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP Science (New York, N.Y.), 2022, 10-14, Volume: 378, Issue:6616 Topics: Animals; Cold Temperature; Cryoelectron Microscopy; Ion Channel Gating; Ligands; Menthol; Mice; Phosphatidylinositol 4,5-Diphosphate; Protein Conformation; Pyrimidinones; Thermosensing; TRPM Cation Channels	2022