memantine and valproic acid

memantine has been researched along with valproic acid in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.35)18.2507
2000's4 (17.39)29.6817
2010's15 (65.22)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Czuczwar, SJ; Dziki, M; Kleinrok, Z; Turski, WA; Urbańska, E1
e Silva, LL; Fernandes, AF; Kowacs, PA; Lange, MC; Mulinari, RA; Oshinsky, M; Piovesan, EJ; Randunz, V; Sereniki, A; Utiumi, M; Vital, M; Werneck, LC1
Alisky, JM1
Chang, YH; Chen, PS; Chen, SL; Hong, JS; Huang, SY; Lee, IH; Lee, SY; Lu, RB; Tzeng, NS; Wang, LJ; Wang, TY; Wang, YS; Yang, YK; Yeh, TL2
Chang, YH; Chen, PS; Chen, SL; Hong, JS; Huang, SY; Lee, IH; Lee, SY; Lu, RB; Tzeng, NS; Wang, LJ; Wang, YS; Yang, YK; Yeh, TL1
Chang, YH; Chen, SH; Chen, SL; Chu, CH; Hong, JS; Huang, SY; Lee, IH; Lee, SY; Lu, RB; Tzeng, NS; Wang, CL; Wang, LJ; Yang, YK; Yeh, TL1
Ene-Stroescu, V; Nguyen, T; Waiblinger, BE1
Kumar, H; Sharma, B1
Chang, YH; Chen, KC; Chen, PS; Chen, SH; Chen, SL; Chu, CH; Chung, YL; Hong, JS; Hsieh, TH; Huang, SY; Lee, IH; Lee, SY; Li, CL; Lu, RB; Tzeng, NS; Wang, LJ; Wang, TY; Yang, YK1
Chang, HH; Chen, PS; Chen, SL; Hong, JS; Huang, SY; Lee, SY; Lu, RB; Wang, TY; Yang, YK1
Chang, YH; Chen, KC; Chen, PS; Chen, SL; Hong, JS; Huang, SY; Lee, IH; Lee, SY; Lu, RB; Tzeng, NS; Wang, LJ; Wang, TY; Yang, YK1
Gmiro, VE; Serdyuk, SE; Veselkina, OS1
Chang, YH; Chen, KC; Chen, PS; Chen, SL; Hong, JS; Huang, SY; Lee, IH; Lee, SY; Lu, RB; Tsai, TY; Tzeng, NS; Wang, TY; Yang, YK1
Finn, DP; Joshi, A; McClean, PL; Todd, S; Wong-Lin, K1
Aboul-Fotouh, S; El-Salam, MFA; Elayat, WM; Elhossiny, RM; Habib, MZ; Hassan, GAM; Mohamad, MI; Zohny, SM1

Reviews

1 review(s) available for memantine and valproic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

8 trial(s) available for memantine and valproic acid

ArticleYear
Inflammation's Association with Metabolic Profiles before and after a Twelve-Week Clinical Trial in Drug-Naïve Patients with Bipolar II Disorder.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Adult; Biomarkers; Bipolar Disorder; Cytokines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Inflammation; Male; Memantine; Psychiatric Status Rating Scales; Psychotropic Drugs; Treatment Outcome; Valproic Acid

2013
Add-on memantine to valproate treatment increased HDL-C in bipolar II disorder.
    Journal of psychiatric research, 2013, Volume: 47, Issue:10

    Topics: Adult; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lipoproteins, HDL; Male; Memantine; Psychiatric Status Rating Scales; Valproic Acid; Young Adult

2013
Genotype variant associated with add-on memantine in bipolar II disorder.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:2

    Topics: Adult; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Double-Blind Method; Drug Therapy, Combination; Female; Genetic Variation; Humans; Male; Memantine; Polymorphism, Genetic; Valproic Acid; Young Adult

2014
The effects of add-on low-dose memantine on cytokine levels in bipolar II depression: a 12-week double-blind, randomized controlled trial.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:3

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Cytokines; Double-Blind Method; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Humans; Linear Models; Male; Memantine; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Treatment Outcome; Valproic Acid; Young Adult

2014
Comparing clinical responses and the biomarkers of BDNF and cytokines between subthreshold bipolar disorder and bipolar II disorder.
    Scientific reports, 2016, 06-07, Volume: 6

    Topics: Adolescent; Adult; Biomarkers; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Cytokines; Dextromethorphan; Double-Blind Method; Female; Humans; Male; Memantine; Placebos; Treatment Outcome; Valproic Acid; Young Adult

2016
Effect of memantine on C-reactive protein and lipid profiles in bipolar disorder.
    Journal of affective disorders, 2017, 10-15, Volume: 221

    Topics: Adult; Antimanic Agents; Bipolar Disorder; C-Reactive Protein; Female; Humans; Lipids; Male; Memantine; Middle Aged; Valproic Acid

2017
Add-On Memantine Treatment for Bipolar II Disorder Comorbid with Alcohol Dependence: A 12-Week Follow-Up Study.
    Alcoholism, clinical and experimental research, 2018, Volume: 42, Issue:6

    Topics: Alcohol Drinking; Alcoholism; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Comorbidity; Cytokines; Diagnosis, Dual (Psychiatry); Dopamine Agents; Drug Therapy, Combination; Follow-Up Studies; Humans; Memantine; Taiwan; Treatment Outcome; Valproic Acid

2018
Add-on memantine may improve cognitive functions and attenuate inflammation in middle- to old-aged bipolar II disorder patients.
    Journal of affective disorders, 2021, 01-15, Volume: 279

    Topics: Aged; Bipolar Disorder; Cognition; Double-Blind Method; Drug Therapy, Combination; Humans; Inflammation; Memantine; Middle Aged; Valproic Acid

2021

Other Studies

14 other study(ies) available for memantine and valproic acid

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Antiparkinsonian drugs memantine and trihexyphenidyl potentiate the anticonvulsant activity of valproate against maximal electroshock-induced seizures.
    Neuropharmacology, 1992, Volume: 31, Issue:10

    Topics: Animals; Anticonvulsants; Antiparkinson Agents; Avoidance Learning; Drug Synergism; Electroshock; Male; Memantine; Memory; Mice; Psychomotor Performance; Seizures; Trihexyphenidyl; Valproic Acid

1992
Influence of NMDA and non-NMDA antagonists on acute and inflammatory pain in the trigeminal territory: a placebo control study.
    Arquivos de neuro-psiquiatria, 2008, Volume: 66, Issue:4

    Topics: Animals; Exploratory Behavior; Facial Pain; Fructose; Inflammation; Male; Memantine; Motor Activity; Pain Measurement; Placebos; Rats; Receptors, N-Methyl-D-Aspartate; Topiramate; Trigeminal Neuralgia; Valproic Acid

2008
Minimally-responsive head injury survivors may have chronic catatonia reversed years after an accident.
    Singapore medical journal, 2009, Volume: 50, Issue:11

    Topics: Accidents; Benzodiazepines; Brain Injuries; Craniocerebral Trauma; Electroconvulsive Therapy; Fructose; Humans; Male; Memantine; Middle Aged; Pilot Projects; Pyridines; Topiramate; Valproic Acid; Zolpidem

2009
Successful treatment of catatonia in a young man with schizophrenia and progressive diffuse cerebral atrophy.
    The Journal of neuropsychiatry and clinical neurosciences, 2014,Winter, Volume: 26, Issue:1

    Topics: Adolescent; Amantadine; Anticonvulsants; Antiparkinson Agents; Antipsychotic Agents; Atrophy; Catatonia; Cerebral Cortex; Clozapine; Drug Therapy, Combination; Humans; Magnetic Resonance Imaging; Male; Memantine; Schizophrenia; Valproic Acid

2014
Memantine ameliorates autistic behavior, biochemistry & blood brain barrier impairments in rats.
    Brain research bulletin, 2016, Volume: 124

    Topics: Animals; Autistic Disorder; Blood-Brain Barrier; Brain; Disease Models, Animal; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Interpersonal Relations; Locomotion; Male; Maze Learning; Memantine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Valproic Acid

2016
[COMPARISON OF CHRONIC ANTICONVULSANT ACTIVITY AND SAFETY OF IEM-2062, SODIUM VALPROATE AND ME-MANTINE IN THE PENTYLENETETRAZOL KINDLING MODEL IN RATS].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2017, Volume: 103, Issue:3

    Topics: Administration, Oral; Animals; Anticonvulsants; Convulsants; Cyclohexanes; Cyclohexylamines; Drug Administration Schedule; Kindling, Neurologic; Locomotion; Male; Memantine; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Valproic Acid

2017
Multi-dimensional relationships among dementia, depression and prescribed drugs in England and Wales hospitals.
    BMC medical informatics and decision making, 2022, 10-07, Volume: 22, Issue:1

    Topics: Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Depression; Donepezil; Dothiepin; Frontotemporal Dementia; Hospitals; Humans; Lamotrigine; Memantine; Mirtazapine; NAD; Sertraline; Valproic Acid; Venlafaxine Hydrochloride; Wales

2022
Memantine/Aripiprazole Combination Alleviates Cognitive Dysfunction in Valproic Acid Rat Model of Autism: Hippocampal CREB/BDNF Signaling and Glutamate Homeostasis.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2023, Volume: 20, Issue:2

    Topics: Animals; Aripiprazole; Autism Spectrum Disorder; Autistic Disorder; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Homeostasis; Male; Memantine; Pregnancy; Rats; Rats, Wistar; Valproic Acid

2023