memantine and riluzole

memantine has been researched along with riluzole in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (27.78)29.6817
2010's11 (61.11)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Coric, V; Kendell, SF; Krystal, JH; Malison, R; Naungayan, C; Pittenger, C; Sanacora, GS1
Bezprozvanny, I; Tang, T; Wu, J1
Howland, RH1
Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Oishi, R; Okuno, R1
Danesh-Meyer, HV; Levin, LA1
Bowser, R; Hank, N; Levine, TD; Saperstein, D1
Owen, RT1
Arranz-Tagarro, JA; Galán, L; García, AG; Gómez-Pinedo, U; Guerrero, A; Martínez-Vila, E; Matías-Guiu, J; Vela, A; Viña, D; Yáñez, M1
Blakeley, J; Brem, H; Gincel, D; Pardo, AC; Rothstein, JD; Tyler, B; Weaver, KD; Yohay, K1
Cryan, JF; Glennon, J; Moloney, RD; O'Connor, RM; Vlachou, S1
Andres, CR; Blasco, H; Corcia, P; Gordon, PH; Patin, F1
Brozka, H; Janikova, M; Radostova, D; Stuchlik, A; Svoboda, J1
Janikova, M; Mainerova, K; Petrasek, T; Stuchlik, A; Svoboda, J; Vojtechova, I1
Chandran, S; Chataway, J; Colville, S; Dakin, RS; Elliott, E; Gregory, JM; Macleod, MR; Mehta, AR; Newton, J; Pal, S; Parker, RA; Parmar, MKB; Stallard, N; Stavrou, M; Steven, M; Swingler, RJ; Weir, CJ; Williamson, J; Wong, C1

Reviews

5 review(s) available for memantine and riluzole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Glutamate-modulating drugs & the treatment of mental disorders.
    Journal of psychosocial nursing and mental health services, 2007, Volume: 45, Issue:1

    Topics: Acamprosate; Amantadine; Cycloserine; Glutamic Acid; Humans; Ketamine; Lamotrigine; Memantine; Mental Disorders; Psychotropic Drugs; Riluzole; Taurine; Triazines

2007
Neuroprotection: extrapolating from neurologic diseases to the eye.
    American journal of ophthalmology, 2009, Volume: 148, Issue:2

    Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Endpoint Determination; Excitatory Amino Acid Antagonists; Glaucoma, Open-Angle; Humans; Memantine; N-Methylaspartate; Nervous System Diseases; Neuroprotective Agents; Optic Nerve Diseases; Riluzole

2009
Glutamatergic approaches in major depressive disorder: focus on ketamine, memantine and riluzole.
    Drugs of today (Barcelona, Spain : 1998), 2012, Volume: 48, Issue:7

    Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Glutamine; Humans; Ketamine; Memantine; Riluzole; Treatment Outcome

2012
Amyotrophic Lateral Sclerosis, 2016: existing therapies and the ongoing search for neuroprotection.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:12

    Topics: Amyotrophic Lateral Sclerosis; Biomarkers; Clinical Trials as Topic; Frontotemporal Dementia; Humans; Hydroxylamines; Memantine; Neuroprotective Agents; Riluzole; Superoxide Dismutase; Vitamin B 12

2016

Trials

2 trial(s) available for memantine and riluzole

ArticleYear
A pilot trial of memantine and riluzole in ALS: correlation to CSF biomarkers.
    Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2010, Volume: 11, Issue:6

    Topics: Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Disease Progression; Excitatory Amino Acid Antagonists; Humans; Memantine; Neuroprotective Agents; Neuropsychological Tests; Pilot Projects; Quality of Life; Riluzole; tau Proteins; Treatment Outcome

2010
Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease.
    BMJ open, 2022, 07-07, Volume: 12, Issue:7

    Topics: Amyotrophic Lateral Sclerosis; Double-Blind Method; Humans; Memantine; Motor Neuron Disease; Neurodegenerative Diseases; Riluzole; Trazodone; Treatment Outcome

2022

Other Studies

11 other study(ies) available for memantine and riluzole

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Visual hallucinations from the addition of riluzole to memantine and bupropion.
    Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:2

    Topics: Adult; Bupropion; Depressive Disorder, Major; Dopamine Uptake Inhibitors; Drug Interactions; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Hallucinations; Humans; Memantine; Riluzole

2006
Evaluation of clinically relevant glutamate pathway inhibitors in in vitro model of Huntington's disease.
    Neuroscience letters, 2006, Oct-30, Volume: 407, Issue:3

    Topics: Amines; Animals; Apoptosis; Cells, Cultured; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Folic Acid; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Lamotrigine; Male; Memantine; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Riluzole; Triazines

2006
Effects of glutamate-related drugs on marble-burying behavior in mice: implications for obsessive-compulsive disorder.
    European journal of pharmacology, 2008, May-31, Volume: 586, Issue:1-3

    Topics: Acoustic Stimulation; Amantadine; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memantine; Mice; Mice, Inbred ICR; Motor Activity; Obsessive-Compulsive Disorder; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Riluzole

2008
The neuroprotection exerted by memantine, minocycline and lithium, against neurotoxicity of CSF from patients with amyotrophic lateral sclerosis, is antagonized by riluzole.
    Neuro-degenerative diseases, 2014, Volume: 13, Issue:2-3

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Excitatory Amino Acid Antagonists; Humans; Lithium; Memantine; Minocycline; Neurons; Neuroprotective Agents; Rats; Riluzole

2014
Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models.
    Journal of neurosurgery, 2014, Volume: 120, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Excitatory Amino Acid Antagonists; Glioma; Memantine; Mice; Polymers; Rats; Riluzole

2014
Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats.
    Neuropharmacology, 2015, Volume: 99

    Topics: Administration, Intravenous; Aging; Amino Acid Transport System X-AG; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Maternal Deprivation; Memantine; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Riluzole; Self Administration; Stress, Psychological

2015
No effect of riluzole and memantine on learning deficit following quinpirole sensitization - An animal model of obsessive-compulsive disorder.
    Physiology & behavior, 2019, 05-15, Volume: 204

    Topics: Animals; Behavior, Animal; Cognition; Disease Models, Animal; Dopamine Agonists; Excitatory Amino Acid Antagonists; Learning; Male; Memantine; Motor Activity; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Riluzole

2019
Memantine and Riluzole Exacerbate, Rather Than Ameliorate Behavioral Deficits Induced by 8-OH-DPAT Sensitization in a Spatial Task.
    Biomolecules, 2021, 07-09, Volume: 11, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Disease Models, Animal; Male; Memantine; Memory; Obsessive-Compulsive Disorder; Rats; Rats, Long-Evans; Riluzole; Spatial Learning

2021