memantine and naloxone

memantine has been researched along with naloxone in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's6 (42.86)29.6817
2010's6 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Popik, P; Skolnick, P1
Danysz, W; Popik, P1
Bespalov, AY; Blokhina, EA; Sukhotina, IA1
Chizh, BA; Englberger, W; Haase, G; Reissmüller, E; Scheede, M; Schlütz, H1
Bisaga, A; Comer, SD; Fischman, MW; Kleber, HD; Popik, P; Ward, AS1
Aguilar, MA; Cauli, O; Maldonado, C; Miñarro, J; Rodríguez-Arias, M1
Bespalov, A; Danysz, W; Kashkin, V; Malyshkin, A; Neznanova, O; Sukhotina, I; Zakharova, E1
Gewirtz, JC; Harris, AC; Rothwell, PE1
Rachamalla, M; Rehni, AK; Singh, N; Tikoo, K1
Etemad, L; Ghazanfari, S; Hosseinzadeh, H; Imenshahidi, M; Moshiri, M1
DiGirolamo, G; Gonzalez, G; Kolodziej, M; Romero-Gonzalez, M; Smelson, D; Ziedonis, D1
Steenbergen, PJ1

Reviews

1 review(s) available for memantine and naloxone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for memantine and naloxone

ArticleYear
The NMDA antagonist memantine attenuates the expression of opioid physical dependence in humans.
    Psychopharmacology, 2001, Volume: 157, Issue:1

    Topics: Adult; Dextromethorphan; Excitatory Amino Acid Antagonists; Female; Humans; Male; Memantine; Morphine; Naloxone; Opioid-Related Disorders; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome

2001
Memantine improves buprenorphine/naloxone treatment for opioid dependent young adults.
    Drug and alcohol dependence, 2015, Nov-01, Volume: 156

    Topics: Adolescent; Adult; Buprenorphine, Naloxone Drug Combination; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Memantine; Naloxone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Recurrence; Young Adult

2015

Other Studies

11 other study(ies) available for memantine and naloxone

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The NMDA antagonist memantine blocks the expression and maintenance of morphine dependence.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:4

    Topics: Amino Acids; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Male; Memantine; Mice; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Receptors, N-Methyl-D-Aspartate

1996
Inhibition of reinforcing effects of morphine and motivational aspects of naloxone-precipitated opioid withdrawal by N-methyl-D-aspartate receptor antagonist, memantine.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Feeding Behavior; Male; Maze Learning; Memantine; Memory; Morphine; Naloxone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Space Perception; Substance Withdrawal Syndrome; Time Factors

1997
Pretreatment with morphine potentiates naloxone-conditioned place aversion in mice: effects of NMDA receptor antagonists.
    European journal of pharmacology, 2000, Oct-13, Volume: 406, Issue:2

    Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Piperazines; Receptors, N-Methyl-D-Aspartate

2000
Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil.
    Neuropharmacology, 2001, Volume: 40, Issue:2

    Topics: Analgesics; Animals; Decerebrate State; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Male; Memantine; Motor Activity; N-Methylaspartate; Naloxone; Narcotic Antagonists; Pain; Piperidines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord

2001
Memantine presents different effects from MK-801 in motivational and physical signs of morphine withdrawal.
    Behavioural brain research, 2003, Sep-15, Volume: 144, Issue:1-2

    Topics: Animals; Behavior, Animal; Conditioning, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Narcotics; Substance Withdrawal Syndrome; Time Factors

2003
The NMDA receptor channel blocker memantine and opioid receptor antagonist naltrexone inhibit the saccharin deprivation effect in rats.
    Behavioural pharmacology, 2004, Volume: 15, Issue:4

    Topics: Acamprosate; Animals; Choice Behavior; Ethanol; Male; Memantine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taurine

2004
Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia.
    Psychopharmacology, 2008, Volume: 196, Issue:4

    Topics: Analgesics, Opioid; Animals; Hyperalgesia; Male; Memantine; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Substance Withdrawal Syndrome

2008
Modulation of histone deacetylase attenuates naloxone-precipitated opioid withdrawal syndrome.
    Naunyn-Schmiedeberg's archives of pharmacology, 2012, Volume: 385, Issue:6

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain; Cysteine Proteinase Inhibitors; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Ileum; In Vitro Techniques; Male; Memantine; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Oligopeptides; Opioid-Related Disorders; Rats; Serpins; Substance Withdrawal Syndrome; Triglycerides; Viral Proteins

2012
Effect of cyanocobalamin (vitamin B12) in the induction and expression of morphine tolerance and dependence in mice.
    Drug research, 2014, Volume: 64, Issue:3

    Topics: Analgesics, Opioid; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Male; Memantine; Mice; Morphine; Morphine Dependence; Naloxone; Pain; Vitamin B 12

2014
Response of zebrafish larvae to mild electrical stimuli: A 96-well setup for behavioural screening.
    Journal of neuroscience methods, 2018, 05-01, Volume: 301

    Topics: Animals; Buprenorphine; Electric Stimulation; Electrodes; Equipment Design; Habituation, Psychophysiologic; Housing, Animal; Larva; Memantine; Models, Animal; Motor Activity; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Proof of Concept Study; Receptors, N-Methyl-D-Aspartate; Zebrafish

2018