memantine has been researched along with morphine in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (16.22) | 18.2507 |
| 2000's | 21 (56.76) | 29.6817 |
| 2010's | 10 (27.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Frey, HH; Voits, M | 1 |
| Chaplan, SR; Malmberg, AB; Yaksh, TL | 1 |
| Danysz, W; Popik, P | 1 |
| Belozertseva, IV | 1 |
| Belozertseva, IV; Bespalov, AY; Dravolina, OA; Sukhotina, IA | 1 |
| Bespalov, A; Danysz, W; Semenova, S | 1 |
| Danysz, W; Kozela, E; Popik, P | 1 |
| Belozertseva, IV; Bespalov, AY; Danysz, W; Dravolina, OA; Neznanova, ON | 1 |
| Schmidt, WJ; Tzchentke, TM | 1 |
| Bespalov, AY; Sukhotina, IA | 1 |
| Kozela, E; Pilc, A; Popik, P | 2 |
| Bespalov, AY; Blokhina, EA; Sukhotina, IA | 1 |
| Bisaga, A; Comer, SD; Fischman, MW; Kleber, HD; Popik, P; Ward, AS | 1 |
| Aguilar, MA; Maldonado, C; Miñarro, J; Rodríguez-Arias, M | 1 |
| Bespalov, AY; Bisaga, A; Popik, P; Rygula, R; Wrobel, M | 1 |
| Aguilar, MA; Cauli, O; Maldonado, C; Miñarro, J; Rodríguez-Arias, M | 1 |
| Aguilar, MA; Manzanedo, C; Miñarro, J; Ribeiro Do Couto, B; Rodríguez-Arias, M | 1 |
| Bisaga, A; Popik, P; Wrobel, M | 1 |
| Bespalov, AY; Danysz, W; Malyshkin, AA; Medvedev, IO | 1 |
| Bespalov, AY; Shekunova, EV | 1 |
| Cheevers, CV; Donello, JE; Gil, DW | 1 |
| Mendez, IA; Trujillo, KA | 1 |
| Gewirtz, JC; Harris, AC; Rothwell, PE | 1 |
| Aguilar, MA; Do Couto, BR; Manzanedo, C; Miñarro, J; Rodríguez-Arias, M | 1 |
| Akagi, M; Ishida, T; Kamei, C; Suga, A | 1 |
| Birbaumer, N; Flor, H; Gustin, SM; Larbig, W; Lotze, M; Schmidt, AC; Schwarz, A; Sines, N; Veit, R | 1 |
| Chen, SH; Chen, SL; Chu, CH; Hong, JS; Lu, RB; Tao, PL; Tseng, LF; Wu, HE | 1 |
| Goebel, A | 1 |
| Rachamalla, M; Rehni, AK; Singh, N; Tikoo, K | 1 |
| Chen, Y; Evola, M; Young, AM | 1 |
| Etemad, L; Ghazanfari, S; Hosseinzadeh, H; Imenshahidi, M; Moshiri, M | 1 |
| Chi, H; Eguchi, S; Iwata, H; Kawano, T; Kumagai, N; Takahashi, Y; Tamura, T; Yamazaki, F; Yokoyama, M | 1 |
| Bourgoin, S; Hamon, M; Kayser, V; Masson, J; Melfort, M; Viguier, F | 1 |
| Äyräpää, A; de C Williams, AC; Elomaa, M; Forss, N; Harno, H; Hotta, J; Kalso, E | 1 |
1 review(s) available for memantine and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for memantine and morphine
| Article | Year |
|---|---|
The NMDA antagonist memantine attenuates the expression of opioid physical dependence in humans.
Topics: Adult; Dextromethorphan; Excitatory Amino Acid Antagonists; Female; Humans; Male; Memantine; Morphine; Naloxone; Opioid-Related Disorders; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2001 |
NMDA-receptor antagonist and morphine decrease CRPS-pain and cerebral pain representation.
Topics: Adult; Aged; Analgesics; Analysis of Variance; Brain Mapping; Cerebral Cortex; Double-Blind Method; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Memantine; Middle Aged; Morphine; Oxygen; Pain; Pain Measurement; Reflex Sympathetic Dystrophy; Time Factors | 2010 |
34 other study(ies) available for memantine and morphine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Effect of psychotropic agents on a model of absence epilepsy in rats.
Topics: Animals; Antidepressive Agents; Dextroamphetamine; Electroencephalography; Epilepsy; Female; Levodopa; Male; Memantine; Morphine; N-Methylaspartate; Parasympatholytics; Psychotropic Drugs; Rats; Rats, Inbred Strains | 1991 |
Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Formaldehyde; Hyperalgesia; Injections, Spinal; Ketamine; Male; Memantine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerves; Touch | 1997 |
Inhibition of reinforcing effects of morphine and motivational aspects of naloxone-precipitated opioid withdrawal by N-methyl-D-aspartate receptor antagonist, memantine.
Topics: Animals; Feeding Behavior; Male; Maze Learning; Memantine; Memory; Morphine; Naloxone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Space Perception; Substance Withdrawal Syndrome; Time Factors | 1997 |
Effects of NMDA receptor channel blockers, dizocilpine and memantine, on the development of opiate analgesic tolerance induced by repeated morphine exposures or social defeats in mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Conflict, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Mice, Inbred BALB C; Morphine; Pain Threshold; Reaction Time; Receptors, N-Methyl-D-Aspartate; Reflex | 1998 |
Morphine tolerance and dependence in mice with history of repeated exposures to NMDA receptor channel blockers.
Topics: Analgesics, Opioid; Animals; Cyclopentanes; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; Interpersonal Relations; Male; Memantine; Mice; Morphine; Morphine Dependence; Reaction Time; Receptors, N-Methyl-D-Aspartate | 1999 |
Low-affinity NMDA receptor channel blockers inhibit acquisition of intravenous morphine self-administration in naive mice.
Topics: Analysis of Variance; Animals; Cyclopentanes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Intravenous; Male; Memantine; Mice; Mice, Inbred DBA; Morphine; Narcotics; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Self Administration | 1999 |
Clinically available NMDA receptor antagonists memantine and dextromethorphan reverse existing tolerance to the antinociceptive effects of morphine in mice.
Topics: Analgesics, Opioid; Animals; Cyclopentanes; Dextromethorphan; Drug Tolerance; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Morphine; Receptors, N-Methyl-D-Aspartate; Tail | 2000 |
Antinociceptive activity of combination of morphine and NMDA receptor antagonists depends on the inter-injection interval.
Topics: Analgesics; Animals; Drug Synergism; Drug Therapy, Combination; Drug Tolerance; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memantine; Mice; Morphine; Piperazines; Receptors, N-Methyl-D-Aspartate | 2000 |
Effects of the non-competitive NMDA-receptor antagonist memantine on morphine- and cocaine-induced potentiation of lateral hypothalamic brain stimulation reward.
Topics: Analgesics, Opioid; Animals; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Drug Synergism; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Male; Memantine; Morphine; Rats; Rats, Long-Evans; Reward | 2000 |
Effects of the NMDA receptor channel blockers memantine and MRZ 2/579 on morphine withdrawal-facilitated aggression in mice.
Topics: Aggression; Animals; Cyclopentanes; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Morphine; Narcotics; Receptors, N-Methyl-D-Aspartate; Social Behavior; Substance Withdrawal Syndrome | 2000 |
Selective agonist of group II glutamate metabotropic receptors, LY354740, inhibits tolerance to analgesic effects of morphine in mice.
Topics: Analgesics, Opioid; Animals; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fentanyl; Male; Memantine; Mice; Morphine; Pain; Pain Measurement; Receptors, Metabotropic Glutamate | 2000 |
Pretreatment with morphine potentiates naloxone-conditioned place aversion in mice: effects of NMDA receptor antagonists.
Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Piperazines; Receptors, N-Methyl-D-Aspartate | 2000 |
Memantine does not block antiaggressive effects of morphine in mice.
Topics: Adaptation, Psychological; Aggression; Animals; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Morphine; Narcotics; Receptors, N-Methyl-D-Aspartate | 2002 |
Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Drug Tolerance; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Mice, Inbred C57BL; Morphine; Pain Measurement; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tail; Time Factors | 2003 |
Effects of memantine, an NMDA receptor antagonist, on place preference conditioned with drug and nondrug reinforcers in mice.
Topics: Animals; Conditioning, Psychological; Excitatory Amino Acid Antagonists; Feeding Behavior; Female; Male; Memantine; Mice; Morphine; Narcotics; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Sexual Behavior, Animal | 2003 |
Memantine presents different effects from MK-801 in motivational and physical signs of morphine withdrawal.
Topics: Animals; Behavior, Animal; Conditioning, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Narcotics; Substance Withdrawal Syndrome; Time Factors | 2003 |
Effects of NMDA receptor antagonists (MK-801 and memantine) on the acquisition of morphine-induced conditioned place preference in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Morphine; Narcotics; Receptors, N-Methyl-D-Aspartate | 2004 |
Reinstatement of morphine-conditioned reward is blocked by memantine.
Topics: Animals; Conditioning, Operant; Dizocilpine Maleate; Dopamine Agents; Excitatory Amino Acid Antagonists; Extinction, Psychological; Learning; Male; Memantine; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Narcotic Antagonists; Narcotics; Reward | 2006 |
Anti-allodynic interactions between NMDA receptor channel blockers and morphine or clonidine in neuropathic rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Analgesics, Opioid; Animals; Clonidine; Cyclopentanes; Dose-Response Relationship, Drug; Drug Interactions; Male; Memantine; Morphine; Pain Measurement; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Sciatic Neuropathy | 2005 |
Effects of memantine on estrogen-dependent acute tolerance to the morphine analgesia in female rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Estradiol; Estrogen Antagonists; Estrogens; Estrous Cycle; Excitatory Amino Acid Antagonists; Female; Memantine; Morphine; Ovariectomy; Rats; Rats, Wistar; Tamoxifen | 2006 |
Transient allodynia pain models in mice for early assessment of analgesic activity.
Topics: Adrenergic alpha-Antagonists; Amines; Amitriptyline; Analgesics; Animals; Clonidine; Cyclohexanecarboxylic Acids; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Memantine; Mice; Mice, Inbred C57BL; Morphine; N-Methylaspartate; Pain; Peripheral Nervous System; Phenylephrine; Piperazines; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Reproducibility of Results; Spinal Cord; Spinal Nerves; Time Factors | 2008 |
NMDA receptor antagonists inhibit opiate antinociceptive tolerance and locomotor sensitization in rats.
Topics: Animals; Behavior, Animal; Buprenorphine; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; Isoquinolines; Male; Memantine; Methadone; Morphine; Motor Activity; Narcotics; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2008 |
Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia.
Topics: Analgesics, Opioid; Animals; Hyperalgesia; Male; Memantine; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Substance Withdrawal Syndrome | 2008 |
Memantine blocks sensitization to the rewarding effects of morphine.
Topics: Analysis of Variance; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Memantine; Mice; Morphine; Motivation; Motor Activity; Narcotics; Receptors, N-Methyl-D-Aspartate; Reward | 2009 |
Effects of anti-dementia drugs on morphine-induced somnolence.
Topics: Animals; Dementia; Donepezil; Electroencephalography; Electromyography; Indans; Male; Memantine; Methylphenidate; Morphine; Piperidines; Rats; Rats, Wistar; Sleep Stages | 2009 |
Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Brain; Brain-Derived Neurotrophic Factor; Drug-Seeking Behavior; Enzyme-Linked Immunosorbent Assay; Interleukin-1beta; Interleukin-6; Male; Memantine; Morphine; Morphine Dependence; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2012 |
Morphine and memantine treatment of long-standing complex regional pain syndrome.
Topics: Adult; Analgesics; Clinical Trials as Topic; Complex Regional Pain Syndromes; Female; Humans; Male; Memantine; Middle Aged; Morphine; Sex Characteristics | 2012 |
Modulation of histone deacetylase attenuates naloxone-precipitated opioid withdrawal syndrome.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain; Cysteine Proteinase Inhibitors; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Ileum; In Vitro Techniques; Male; Memantine; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Oligopeptides; Opioid-Related Disorders; Rats; Serpins; Substance Withdrawal Syndrome; Triglycerides; Viral Proteins | 2012 |
Memantine and dizocilpine interactions with antinociceptive or discriminative stimulus effects of morphine in rats after acute or chronic treatment with morphine.
Topics: Analgesics, Opioid; Animals; Discrimination Learning; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Male; Memantine; Morphine; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Reinforcement Schedule | 2013 |
Effect of cyanocobalamin (vitamin B12) in the induction and expression of morphine tolerance and dependence in mice.
Topics: Analgesics, Opioid; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Male; Memantine; Mice; Morphine; Morphine Dependence; Naloxone; Pain; Vitamin B 12 | 2014 |
Postoperative pain impairs subsequent performance on a spatial memory task via effects on N-methyl-D-aspartate receptor in aged rats.
Topics: Age Factors; Amides; Anesthetics; Animals; Hippocampus; Isoflurane; Male; Maze Learning; Memantine; Memory; Morphine; Pain, Postoperative; Protein Subunits; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Ropivacaine | 2013 |
Altered nociception in mice with genetically induced hypoglutamatergic tone.
Topics: Analgesics, Opioid; Animals; Excitatory Amino Acid Antagonists; Glutamates; Glutaminase; Hot Temperature; Male; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Nociception; Phenotype; Physical Stimulation; Receptors, N-Methyl-D-Aspartate | 2015 |
Symptom reduction and improved function in chronic CRPS type 1 after 12-week integrated, interdisciplinary therapy.
Topics: Adult; Ambulatory Care; Analgesics; Chronic Pain; Combined Modality Therapy; Complex Regional Pain Syndromes; Female; Humans; Memantine; Middle Aged; Morphine; Physical Therapy Modalities; Psychotherapy; Quality of Life; Treatment Outcome; Upper Extremity | 2019 |