melphalan has been researched along with nornitrogen-mustard* in 1 studies
1 other study(ies) available for melphalan and nornitrogen-mustard
Article | Year |
---|---|
Covalent binding of nitrogen mustards to the cysteine-34 residue in human serum albumin.
Covalent binding of various clinically important nitrogen mustards to the cysteine-34 residue of human serum albumin, in vitro and in vivo, is demonstrated. A rapid method for detection of these adducts is presented, based on liquid chromatography-tandem mass spectrometry analysis of the adducted tripeptide Cys*-Pro-Phe after digestion of the protein with Pronase. Topics: Binding Sites; Chlorambucil; Cyclophosphamide; Cysteine; Drug Monitoring; Humans; In Vitro Techniques; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Protein Binding; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2002 |