melphalan has been researched along with formononetin* in 1 studies
1 other study(ies) available for melphalan and formononetin
Article | Year |
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Synthesis and antitumor activity of formononetin nitrogen mustard derivatives.
A series of formononetin nitrogen mustard derivatives were synthesized and evaluated in vitro for their cytotoxicity against five cancer cell lines (SH-SY5Y, HCT-116, DU-145, Hela and SGC-7901). The pharmacological results showed that many of the new derivatives displayed more potent cytotoxicity than alkeran. Furthermore, compounds 6d and 6n could induce cell cycle arrest at G2/M phase and cell apoptosis. Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Inhibitory Concentration 50; Isoflavones; Mechlorethamine | 2012 |