melphalan and formononetin

melphalan has been researched along with formononetin* in 1 studies

Other Studies

1 other study(ies) available for melphalan and formononetin

Article	Year
Synthesis and antitumor activity of formononetin nitrogen mustard derivatives. European journal of medicinal chemistry, 2012, Volume: 54 A series of formononetin nitrogen mustard derivatives were synthesized and evaluated in vitro for their cytotoxicity against five cancer cell lines (SH-SY5Y, HCT-116, DU-145, Hela and SGC-7901). The pharmacological results showed that many of the new derivatives displayed more potent cytotoxicity than alkeran. Furthermore, compounds 6d and 6n could induce cell cycle arrest at G2/M phase and cell apoptosis. Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Inhibitory Concentration 50; Isoflavones; Mechlorethamine	2012

Article

Year

Synthesis and antitumor activity of formononetin nitrogen mustard derivatives.

European journal of medicinal chemistry, 2012, Volume: 54

A series of formononetin nitrogen mustard derivatives were synthesized and evaluated in vitro for their cytotoxicity against five cancer cell lines (SH-SY5Y, HCT-116, DU-145, Hela and SGC-7901). The pharmacological results showed that many of the new derivatives displayed more potent cytotoxicity than alkeran. Furthermore, compounds 6d and 6n could induce cell cycle arrest at G2/M phase and cell apoptosis.

Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Inhibitory Concentration 50; Isoflavones; Mechlorethamine

2012