melphalan and 5-bromosalicylaldehyde

melphalan has been researched along with 5-bromosalicylaldehyde* in 1 studies

Other Studies

1 other study(ies) available for melphalan and 5-bromosalicylaldehyde

Article	Year
Gallium (III) Complexes with 5-Bromosalicylaldehyde Benzoylhydrazones: In Silico Studies and In Vitro Cytotoxic Activity. Molecules (Basel, Switzerland), 2022, Aug-26, Volume: 27, Issue:17 Gallium (III) complexes with the ligands 5-bromosalicylaldehyde-4-hydroxybenzoylhydrazone and 5-bromosalicylaldehyde isonicotinoylhydrazone were synthesized to receive compounds with improved antiproliferative action. Compounds were characterized by elemental analysis, IR, and NMR spectroscopy. Density functional theory calculations with Becke's 3-parameter hybrid functional and 6-31+G(d,p) basis set were carried out to investigate the structural features of the ligands and Ga(III) complexes. Cytotoxic screening by MTT-dye reduction assay was carried out using cisplatin and melphalan as reference cytotoxic agents. A general formula [Ga(HL) Topics: Aldehydes; Antineoplastic Agents; Cisplatin; Coordination Complexes; Drug Screening Assays, Antitumor; Gallium; Humans; Ligands; Melphalan; Oxygen	2022

Article

Year

Gallium (III) Complexes with 5-Bromosalicylaldehyde Benzoylhydrazones: In Silico Studies and In Vitro Cytotoxic Activity.

Molecules (Basel, Switzerland), 2022, Aug-26, Volume: 27, Issue:17

Gallium (III) complexes with the ligands 5-bromosalicylaldehyde-4-hydroxybenzoylhydrazone and 5-bromosalicylaldehyde isonicotinoylhydrazone were synthesized to receive compounds with improved antiproliferative action. Compounds were characterized by elemental analysis, IR, and NMR spectroscopy. Density functional theory calculations with Becke's 3-parameter hybrid functional and 6-31+G(d,p) basis set were carried out to investigate the structural features of the ligands and Ga(III) complexes. Cytotoxic screening by MTT-dye reduction assay was carried out using cisplatin and melphalan as reference cytotoxic agents. A general formula [Ga(HL)

Topics: Aldehydes; Antineoplastic Agents; Cisplatin; Coordination Complexes; Drug Screening Assays, Antitumor; Gallium; Humans; Ligands; Melphalan; Oxygen

2022